Hydrophilic copolymer and medical device

    公开(公告)号:US11377512B2

    公开(公告)日:2022-07-05

    申请号:US16282929

    申请日:2019-02-22

    摘要: A hydrophilic copolymer that can form a surface lubricious layer exhibiting superior lubricating property and durability (lubrication retaining property), is provided. A hydrophilic copolymer having a good solvent solubility is provided. A hydrophilic copolymer is provided containing: structural units derived from a polymerizable monomer (A) having a sulfobetaine structure; structural units derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and groups of salts thereof; and structural units derived from a polymerizable monomer (C) having a photoreactive group.

    Medical instrument
    2.
    发明授权

    公开(公告)号:US11872326B2

    公开(公告)日:2024-01-16

    申请号:US16996017

    申请日:2020-08-18

    摘要: Disclosed is a medical device exhibiting superior lubricating property and durability (lubrication retaining property), the medical device comprising a substrate layer, an adhesive layer formed on at least a portion of the substrate layer, comprising a hydrophilic copolymer comprising a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group, sulfuric acid group, sulfurous acid group, and salts thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group, and a surface lubricious layer formed on at least a portion of the adhesive layer, comprising a hydrophilic polymer dissolvable in a solvent capable of dissolving or swelling the hydrophilic copolymer. Also disclosed are methods for producing medical devices exhibiting superior lubricating property and durability (lubrication retaining property).