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公开(公告)号：US11130127B2
公开(公告)日：2021-09-28
申请号：US16777795
申请日：2020-01-30
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Ahmed Zobi , Justin Stovner , Hugo Salas , David Duarte , Jered Haun , Alan Widgerow , Derek Banyard
Abstract: Provided herein are devices and methods of processing a sample that include, in several embodiments, rotating one or more microfluidic chips that are mounted on a support plate using a motor driven rotational chuck. By spinning one or more of the microfluidic chips about a common center of rotation in a controlled manner, high flow rates (and high shear forces) are imparted to the sample in a controlled manner. Each microfluidic chip can be rotated 180° on the support plate so that the sample can be run back-and-forth through the microfluidic devices. Because the support plate can be driven at relatively high RPMs, high flow rates are generated within the microfluidic chips. This increases the shear forces on the sample and also decreases the processing time involved as the sample can quickly pass through the shear-inducing features of the microfluidic chip(s).
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Patent Agency Ranking
公开(公告)号：US12201978B2
公开(公告)日：2025-01-21
申请号：US17412841
申请日：2021-08-26
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Ahmed Zobi , Justin Stovner , Hugo Salas , David Duarte , Jered Haun , Alan Widgerow , Derek Banyard
Abstract: Provided herein are devices and methods of processing a sample that include, in several embodiments, rotating one or more microfluidic chips that are mounted on a support plate using a motor driven rotational chuck. By spinning one or more of the microfluidic chips about a common center of rotation in a controlled manner, high flow rates (and high shear forces) are imparted to the sample in a controlled manner. Each microfluidic chip can be rotated 180° on the support plate so that the sample can be run back-and-forth through the microfluidic devices. Because the support plate can be driven at relatively high RPMs, high flow rates are generated within the microfluidic chips. This increases the shear forces on the sample and also decreases the processing time involved as the sample can quickly pass through the shear-inducing features of the microfluidic chip(s).
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公开(公告)号：US20220097050A1
公开(公告)日：2022-03-31
申请号：US17412841
申请日：2021-08-26
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Ahmed Zobi , Justin Stovner , Hugo Salas , David Duarte , Jered Haun , Alan Widgerow , Derek Banyard
Abstract: Provided herein are devices and methods of processing a sample that include, in several embodiments, rotating one or more microfluidic chips that are mounted on a support plate using a motor driven rotational chuck. By spinning one or more of the microfluidic chips about a common center of rotation in a controlled manner, high flow rates (and high shear forces) are imparted to the sample in a controlled manner. Each microfluidic chip can be rotated 180° on the support plate so that the sample can be run back-and-forth through the microfluidic devices. Because the support plate can be driven at relatively high RPMs, high flow rates are generated within the microfluidic chips. This increases the shear forces on the sample and also decreases the processing time involved as the sample can quickly pass through the shear-inducing features of the microfluidic chip(s).
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公开(公告)号：US10589268B2
公开(公告)日：2020-03-17
申请号：US16101254
申请日：2018-08-10
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Ahmed Zobi , Justin Stovner , Hugo Salas , David Duarte , Jered Haun , Alan Widgerow , Derek Banyard
Abstract: Provided herein are devices and methods of processing a sample that include, in several embodiments, rotating one or more microfluidic chips that are mounted on a support plate using a motor driven rotational chuck. By spinning one or more of the microfluidic chips about a common center of rotation in a controlled manner, high flow rates (and high shear forces) are imparted to the sample in a controlled manner. Each microfluidic chip can be rotated 180° on the support plate so that the sample can be run back-and-forth through the microfluidic devices. Because the support plate can be driven at relatively high RPMs, high flow rates are generated within the microfluidic chips. This increases the shear forces on the sample and also decreases the processing time involved as the sample can quickly pass through the shear-inducing features of the microfluidic chip(s).
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公开(公告)号：US20200164374A1
公开(公告)日：2020-05-28
申请号：US16777795
申请日：2020-01-30
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Ahmed Zobi , Justin Stovner , Hugo Salas , David Duarte , Jered Haun , Alan Widgerow , Derek Banyard
Abstract: Provided herein are devices and methods of processing a sample that include, in several embodiments, rotating one or more microfluidic chips that are mounted on a support plate using a motor driven rotational chuck. By spinning one or more of the microfluidic chips about a common center of rotation in a controlled manner, high flow rates (and high shear forces) are imparted to the sample in a controlled manner. Each microfluidic chip can be rotated 180° on the support plate so that the sample can be run back-and-forth through the microfluidic devices. Because the support plate can be driven at relatively high RPMs, high flow rates are generated within the microfluidic chips. This increases the shear forces on the sample and also decreases the processing time involved as the sample can quickly pass through the shear-inducing features of the microfluidic chip(s).
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公开(公告)号：US20180361382A1
公开(公告)日：2018-12-20
申请号：US16101254
申请日：2018-08-10
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Ahmed Zobi , Justin Stovner , Hugo Salas , David Duarte , Jered Haun , Alan Widgerow , Derek Banyard
Abstract: Provided herein are devices and methods of processing a sample that include, in several embodiments, rotating one or more microfluidic chips that are mounted on a support plate using a motor driven rotational chuck. By spinning one or more of the microfluidic chips about a common center of rotation in a controlled manner, high flow rates (and high shear forces) are imparted to the sample in a controlled manner. Each microfluidic chip can be rotated 180° on the support plate so that the sample can be run back-and-forth through the microfluidic devices. Because the support plate can be driven at relatively high RPMs, high flow rates are generated within the microfluidic chips. This increases the shear forces on the sample and also decreases the processing time involved as the sample can quickly pass through the shear-inducing features of the microfluidic chip(s).
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