公开(公告)号：US11311724B2

公开(公告)日：2022-04-26

申请号：US16047535

申请日：2018-07-27

Applicant: The Regents of the University of California

Inventor： Imanuel Lerman ,  Ramesh Rao ,  Donald Kimball ,  Alan Simmons ,  Dewleen Baker ,  Mingxiong Huang ,  Edward Zhong ,  Bryan Davis

IPC: A61B5/00 ,  A61N1/36 ,  A61B5/0205 ,  A61B5/16 ,  A61N1/02 ,  A61N7/00 ,  A61B5/024 ,  A61B5/0533 ,  A61B5/026 ,  A61B5/08 ,  A61B5/11 ,  A61B5/01 ,  A61N1/04 ,  A61B5/291 ,  A61B5/332

Abstract: In an example, physiological signal(s) are received from physiological sensor(s) configured to measure at least one physiological property of a user. An arousal of at least one characteristic of at least one treatment resistant mood disorder is detected through employment of an estimation method based at least in part on at least one of the physiological signal(s). A value for at least one of a plurality of stimulation parameters is selected based at least in part on at least one of the physiological signal(s). An electric field based at least in part on the arousal is produced. The electric field is configured to stimulate at least a portion of a median nerve of the user transcutaneously. The electric field is based at least in part on at least some of the plurality of stimulation parameters.

公开(公告)号：US20250082258A1

公开(公告)日：2025-03-13

申请号：US18292659

申请日：2022-07-25

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Imanuel Lerman ,  Ramesh Rao ,  Ming-Xiong Huang ,  Todd P. Coleman ,  Yifeng Bu

IPC: A61B5/00 ,  A61B5/248 ,  A61B5/388 ,  G16H10/60

Abstract: Disclosed are devices, systems and methods for neural signal detection of immune responses. In some aspects, a system includes a processing unit: a receiving unit configured to receive at least one sensor signal from a wearable sensor, where the wearable sensor is configured to detect at least one neural signal of a patient; and a tangible non-transitory computer readable medium having instructions configured to cause the processing unit to automatically receive a data signal from the receiving unit, automatically detect an immune response based at least in part on the data signal, automatically create a notification based at least in part on the immune response, and automatically present the notification to a user of the system.

公开(公告)号：US20190030334A1

公开(公告)日：2019-01-31

申请号：US16047535

申请日：2018-07-27

Applicant: The Regents of the University of California

Inventor： Imanuel Lerman ,  Ramesh Rao ,  Donald Kimball ,  Alan Simmons ,  Dewleen Baker ,  Mingxiong Huang ,  Edward Zhong ,  Bryan Davis

IPC: A61N1/36 ,  A61N1/04 ,  A61B5/0205 ,  A61B5/16 ,  A61B5/00 ,  A61N1/02 ,  A61N7/00

Abstract: In an example, physiological signal(s) are received from physiological sensor(s) configured to measure at least one physiological property of a user. An arousal of at least one characteristic of at least one treatment resistant mood disorder is detected through employment of an estimation method based at least in part on at least one of the physiological signal(s). A value for at least one of a plurality of stimulation parameters is selected based at least in part on at least one of the physiological signal(s). An electric field based at least in part on the arousal is produced. The electric field is configured to stimulate at least a portion of a median nerve of the user transcutaneously. The electric field is based at least in part on at least some of the plurality of stimulation parameters.