公开(公告)号：US20180296992A1

公开(公告)日：2018-10-18

申请号：US15767979

申请日：2016-10-07

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Dino Di Carlo ,  Soroush Kahkeshani

IPC: B01F3/08 ,  B01F13/00 ,  A61K9/00

CPC classification number: B01F3/0815 ,  A61K9/0009 ,  A61K9/0021 ,  A61K9/0024 ,  A61K9/0097 ,  A61M2037/0023 ,  B01F13/0059 ,  B01F13/0077 ,  B01L3/502761 ,  B01L3/502784 ,  B01L2200/0668 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2400/043 ,  G01N35/1002 ,  G01N2035/1034

Abstract: A microfluidic device for forming droplets includes at least one ferrofluid reservoir disposed in the microfluidic device and containing a ferrofluid therein. The microfluidic device includes a continuous-phase reservoir disposed in the microfluidic device and containing an oil phase therein and one or more microfluidic channels connecting between the at least one ferrofluid reservoir and the continuous-phase reservoir, the continuous-phase reservoir comprising a step region having an increased height as compared to a height of the one or more microfluidic channels. To form droplets an externally applied magnetic field is applied to the device to pull the ferrofluid into the continuous-phase reservoir, whereby droplets are formed at step region.

公开(公告)号：US20200289995A1

公开(公告)日：2020-09-17

申请号：US16888563

申请日：2020-05-29

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Dino Di Carlo ,  Soroush Kahkeshani

IPC: B01F3/08 ,  A61K9/00 ,  B01F13/00 ,  B01L3/00 ,  G01N35/10

Abstract: A microfluidic device for forming droplets includes at least one ferrofluid reservoir disposed in the microfluidic device and containing a ferrofluid therein. The microfluidic device includes a continuous-phase reservoir disposed in the microfluidic device and containing an oil phase therein and one or more microfluidic channels connecting between the at least one ferrofluid reservoir and the continuous-phase reservoir, the continuous-phase reservoir comprising a step region having an increased height as compared to a height of the one or more microfluidic channels. To form droplets an externally applied magnetic field is applied to the device to pull the ferrofluid into the continuous-phase reservoir, whereby droplets are formed at step region.

公开(公告)号：US11596909B2

公开(公告)日：2023-03-07

申请号：US16888563

申请日：2020-05-29

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Dino Di Carlo ,  Soroush Kahkeshani

IPC: B01F23/411 ,  A61K9/00 ,  B01L3/00 ,  B01F33/30 ,  B01F33/3032 ,  A61M37/00 ,  G01N35/10

Abstract: A microfluidic device for forming droplets includes at least one ferrofluid reservoir disposed in the microfluidic device and containing a ferrofluid therein. The microfluidic device includes a continuous-phase reservoir disposed in the microfluidic device and containing an oil phase therein and one or more microfluidic channels connecting between the at least one ferrofluid reservoir and the continuous-phase reservoir, the continuous-phase reservoir comprising a step region having an increased height as compared to a height of the one or more microfluidic channels. To form droplets an externally applied magnetic field is applied to the device to pull the ferrofluid into the continuous-phase reservoir, whereby droplets are formed at step region.

公开(公告)号：US10688453B2

公开(公告)日：2020-06-23

申请号：US15767979

申请日：2016-10-07

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Dino Di Carlo ,  Soroush Kahkeshani

IPC: B01F13/00 ,  A61K9/00 ,  B01F3/08 ,  G01N35/10 ,  B01L3/00 ,  A61M37/00

Abstract: A microfluidic device for forming droplets includes at least one ferrofluid reservoir disposed in the microfluidic device and containing a ferrofluid therein. The microfluidic device includes a continuous-phase reservoir disposed in the microfluidic device and containing an oil phase therein and one or more microfluidic channels connecting between the at least one ferrofluid reservoir and the continuous-phase reservoir, the continuous-phase reservoir comprising a step region having an increased height as compared to a height of the one or more microfluidic channels. To form droplets an externally applied magnetic field is applied to the device to pull the ferrofluid into the continuous-phase reservoir, whereby droplets are formed at step region.