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Patent Agency Ranking
公开(公告)号：US10779963B2
公开(公告)日：2020-09-22
申请号：US16404343
申请日：2019-05-06
Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Inventor： Cynthia Anne Chestek , Melanie G. Urbanchek , Paul S. Cederna , Richard Brent Gillespie , Nicholas B. Langhals , Zachary Irwin , Daniel C. Ursu
Abstract: The present disclosure provides methods and systems for receiving, with processing circuitry of an implant device, an electrical signal from a free tissue graft attached to a portion of a nerve (e.g., a nerve branch or fascicle) through an electrical conductor in electrical communication with the free tissue graft (e.g., muscle graft), the nerve having reinnervated the free tissue graft. The electrical signal from the free tissue graft has a voltage amplitude of greater than or equal to about 150 microvolts. The processing circuitry stores signal data corresponding to the electrical signal from the free tissue graft in a memory accessible to the processing circuitry.
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公开(公告)号：US20210268277A1
公开(公告)日：2021-09-02
申请号：US17254786
申请日：2019-06-21
Applicant: The Regents of the University of Michigan
Inventor： Cynthia Anne Chestek , Elissa Joy Welle , John Paul Seymour , Lauren Leigh Zimmerman , Zhonghua Ouyang , Paras Rajni Patel , Ahmad Jiman , Timothy Morris Bruns
Abstract: A carbon fiber implantable probe, a method of manufacturing the carbon implantable probe, and a method of implanting the probe in an implantation site, such as a nerve. The carbon fiber implantable probe includes a flexible probe body, a carbon fiber microarray (CFMA) composing one or more carbon fiber electrodes at least partially embedded in the flexible probe body, and a signal conductor connected to the one or more carbon fiber electrodes of the CFMA. In one example, the CFMA includes carbon fiber electrodes having conductive carbon coms partially surrounded by an insulative coating. The combination of the CFMA with the flexible probe body, made of silicone rubber for example, can improve implantation processes.
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公开(公告)号：US11911128B2
公开(公告)日：2024-02-27
申请号：US17173976
申请日：2021-02-11
Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Inventor： David T. Blaauw , Jamie Phillips , Cynthia Anne Chestek , Taekwang Jang , Hun-Seok Kim , Dennis Sylvester , Jongyup Lim , Eunseong Moon , Michael Barrow , Samuel Nason , Julianna Richie , Paras Patel
IPC: A61B5/00 , H04B10/80 , H04B10/114 , A61B5/37 , A61B5/384
CPC classification number: A61B5/0017 , A61B5/0006 , A61B5/0031 , A61B5/37 , A61B5/384 , H04B10/114 , H04B10/80 , A61B2560/0219
Abstract: A mote includes an optical receiver that wirelessly receives a power and data signal in form of NIR light energy within a patient and converts the NIR light energy to an electrical signal having a supply voltage. A control module supplies the supply voltage to power devices of the mote. A clock generation circuit locks onto a target clock frequency based on the power and data signal and generates clock signals. A data recovery circuit sets parameters of one of the devices based on the power and data signal and a first clock signal. An amplifier amplifies a neuron signal detected via an electrode inserted in tissue of the patient. A chip identifier module, based on a second clock signal, generates a recorded data signal based on a mote chip identifier and the neuron signal. A driver transmits the recorded data signal via a LED or a RF transmitter.
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公开(公告)号：US11185344B2
公开(公告)日：2021-11-30
申请号：US15556893
申请日：2016-03-11
Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Inventor： Nicholas B. Langhals , Cynthia Anne Chestek , Paul S. Cederna , Albert Shih , Melanie G. Urbanchek , Grant H. Kruger , Jeffrey Stephen Plott , Jordan T. Kreda
IPC: A61B17/295 , A61B17/3205 , A61B17/34 , A61B17/29 , A61B17/11 , A61B90/00 , A61B17/00
Abstract: The present disclosure provides a mechanically-actuated tool for cutting a tissue graft having a hollow core and methods for use thereof. A portion of a biological structure, such as a nerve, is attached to the hollow core to form an implantable neural graft assembly. The tool has a cutter mechanism and a grasper mechanism. The grasper mechanism has one or more component(s) that open and close via an actuation mechanism, like a handle, and rotate via a controller component, like a rotatable wheel. The cutter mechanism may be a cutting tube component that harvests the tissue graft. The tool may also have an ejector mechanism to remove the tissue graft as part of the implantable neural graft assembly. Such devices and methods are particularly suitable for treating neuromas and other neural regeneration procedures.
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公开(公告)号：US10314725B2
公开(公告)日：2019-06-11
申请号：US14940703
申请日：2015-11-13
Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Inventor： Cynthia Anne Chestek , Melanie G. Urbanchek , Paul S. Cederna , Richard Brent Gillespie , Nicholas B. Langhals , Zachary Irwin , Daniel C. Ursu
Abstract: The present disclosure provides methods and systems for receiving, with processing circuitry of an implant device, an electrical signal from a free tissue graft attached to a portion of a nerve (e.g., a nerve branch or fascicle) through an electrical conductor in electrical communication with the free tissue graft (e.g., muscle graft), the nerve having reinnervated the free tissue graft. The electrical signal from the free tissue graft has a voltage amplitude of greater than or equal to about 150 microvolts. The processing circuitry stores signal data corresponding to the electrical signal from the free tissue graft in a memory accessible to the processing circuitry.
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