公开(公告)号：US20180071545A1

公开(公告)日：2018-03-15

申请号：US15563705

申请日：2016-04-01

Applicant: The University of Tokyo ,  OSAKA UNIVERSITY

Inventor： Youichi SAITOH ,  Masaki SEKINO ,  Yu MIYAWAKI ,  Keita YAMAMOTO

IPC: A61N2/02 ,  A61N2/00

CPC classification number: A61N2/02 ,  A61N1/40 ,  A61N2/006 ,  A61N2/008

Abstract: A coil apparatus for use in a transcranial magnetic stimulation apparatus is provided in which the coil apparatus includes a coil arranged to oppose a surface of a head of a human to generate a current by an induced electric field in a magnetic stimulation-target region in a brain by electromagnetic induction, and to stimulate neurons. The coil apparatus includes the coil configured by winding a conductive wire along a predetermined reference surface; and a magnetic body arranged between the head and the coil to oppose the coil, and arranged at a position at an opposite side of the head. The magnetic body is provided for flowing a current therein by an induced electric field when the coil is driven, and for increasing the current flowing by the induced electric field in a magnetic stimulation-target region of the brain as compared with that with no magnetic body.

公开(公告)号：US20170049387A1

公开(公告)日：2017-02-23

申请号：US15118704

申请日：2015-02-06

Applicant: The University of Tokyo ,  OSAKA UNIVERSITY

Inventor： Youichi SAITOH ,  Masaki SEKINO ,  Yoshihiro TAKIYAMA ,  Keita YAMAMOTO

IPC: A61B5/00 ,  A61B5/055 ,  G06T15/08 ,  A61N2/02

CPC classification number: A61B5/4848 ,  A61B5/055 ,  A61B5/4064 ,  A61B5/742 ,  A61B34/10 ,  A61N2/006 ,  A61N2/02 ,  G06F19/00 ,  G06T15/08 ,  G06T2210/41 ,  G16H50/50

Abstract: An intracerebral current simulation method including a first step of providing head image data; a second step of forming a three-dimensional brain model including micro-polyhedron units; a third step of providing first information which includes conditions under which a coil is placed on a patient's head, an electric current is applied to the coil, and the patient's reaction to the magnetic stimulation is observed, the conditions including a position and orientation of the coil, an electric current applied to the coil, and a structure relating to a generated magnetic field of the coil; and a fourth step of calculating an eddy current or electric field induced inside each of the micro-polyhedron units on the basis of the first information provided in the third step and second information which includes conductivity assigned to each micro-polyhedron unit. Also disclosed is a transcranial magnetic stimulation device and system.

Abstract translation: 一种脑内电流模拟方法，包括提供头部图像数据的第一步骤; 形成包括微​​多面体单元的三维脑模型的第二步骤; 提供第一信息的第三步骤，其包括将线圈放置在患者头部上的条件，向线圈施加电流，并且观察患者对磁刺激的反应，条件包括位置和方位 线圈，施加到线圈的电流，以及与线圈的产生的磁场有关的结构; 以及第四步骤，基于第三步骤中提供的第一信息和包括分配给每个微多面体单元的电导率的第二信息来计算在每个微多面体单元内感应的涡流或电场。 还公开了经颅磁刺激装置和系统。

公开(公告)号：US20180369601A1

公开(公告)日：2018-12-27

申请号：US15563044

申请日：2016-03-30

Applicant: The University of Tokyo ,  OSAKA UNIVERSITY

Inventor： Youichi SAITOH ,  Masaki SEKINO ,  Keita YAMAMOTO

IPC: A61N2/02 ,  A61N2/00 ,  A61N1/40 ,  A61B5/00

Abstract: A coil apparatus for use in a transcranial magnetic stimulation apparatus is provided to further increase an electric field intensity on a head surface. The coil apparatus includes a wound-wire coil disposed on or near a head surface so as to generate a current by an induced electric field through electromagnetic induction in a magnetic stimulation-target region of a brain for stimulating neurons. The wound-wire coil includes a near-head-surface conductive wire portion disposed on or near the head surface, and a far-head-surface conductive wire portion disposed farther from the head surface than the near-head-surface conductive wire portion. A distance between the near-head-surface conductive wire portion and the far-head-surface conductive wire portion is set to be changed so that an intensity of the induced electric field becomes larger than that of a surrounding region of the magnetic stimulation-target region.

公开(公告)号：US20160346562A1

公开(公告)日：2016-12-01

申请号：US15117377

申请日：2015-02-13

Applicant: OSAKA UNIVERSITY ,  THE UNIVERSITY OF TOKYO

Inventor： Youichi SAITOH ,  Masaki SEKINO ,  Momoko SUYAMA ,  Keita YAMAMOTO

IPC: A61N2/02 ,  A61N2/00

CPC classification number: A61N2/02 ,  A61N2/006

Abstract: A coil device for transcranial magnetic stimulation treatment, that generates an overcurrent uniformly across a wide range inside the head of a patient. The coil device includes a winding frame and a coil. A cylindrical surface of the winding frame has: an inner surface section arranged near the cranial surface during use; and an outer surface section forming a convex curved surface protruding towards the outside of the cylindrical surface, relative to a first direction parallel to a neutral axis and a second direction orthogonal to the first direction. The neutral axis draws a convex curve.

Abstract translation: 一种用于经颅磁刺激治疗的线圈装置，其在患者头部内部的宽范围内均匀地产生过电流。 线圈装置包括绕组框架和线圈。 卷绕框架的圆柱形表面具有：在使用期间布置在颅表面附近的内表面部分; 以及外表面部分，形成相对于平行于中立轴线的第一方向和与第一方向正交的第二方向朝向圆柱形表面的外侧突出的凸曲面。 中性轴绘制凸曲线。

公开(公告)号：US20200230431A1

公开(公告)日：2020-07-23

申请号：US16842124

申请日：2020-04-07

Applicant: THE UNIVERSITY OF TOKYO ,  OSAKA UNIVERSITY

Inventor： Youichi SAITOH ,  Masaki SEKINO ,  Keita YAMAMOTO

IPC: A61N2/02 ,  A61N1/40 ,  A61N2/00 ,  A61F2/04 ,  A61B5/00

Abstract: A coil apparatus for use in a transcranial magnetic stimulation apparatus is provided to further increase an electric field intensity on a head surface. The coil apparatus includes a wound-wire coil disposed on or near a head surface so as to generate a current by an induced electric field through electromagnetic induction in a magnetic stimulation-target region of a brain for stimulating neurons. The wound-wire coil includes a near-head-surface conductive wire portion disposed on or near the head surface, and a far-head-surface conductive wire portion disposed farther from the head surface than the near-head-surface conductive wire portion. A distance between the near-head-surface conductive wire portion and the far-head-surface conductive wire portion is set to be changed so that an intensity of the induced electric field becomes larger than that of a surrounding region of the magnetic stimulation-target region.

公开(公告)号：US20180280711A1

公开(公告)日：2018-10-04

申请号：US15763917

申请日：2017-02-28

Applicant: THE UNIVERSITY OF TOKYO

Inventor： Masaki SEKINO ,  Keita YAMAMOTO ,  Yuta KAWASAKI

IPC: A61N2/00 ,  A61N2/02

Abstract: A coil 31 has 1st to Nth turns 311 to 31N. The 1st to Nth turns 311 to 31N are respectively provided with actuation parts 311a for current in one direction to flow, and connection parts 311b for current in the opposite direction to the one direction to flow. The plurality of actuation parts 311a are arranged substantially parallel to each other, and are arranged along a surface of an object 1 or a surface that approximates to the surface of the object 1. A plurality of connection parts 311b are arranged within a space in which the connection parts do not face the surface of the object 1 over the actuation parts 311a of the 1st to Nth turns, and the connection parts are positioned at the sides with respect to the extension direction of the actuation parts 311a.