公开(公告)号：US10537721B2

公开(公告)日：2020-01-21

申请号：US15241788

申请日：2016-08-19

Applicant: TOPPAN PRINTING CO., LTD.

Inventor： Hisami Ueno

IPC: A61M37/00

Abstract: A microneedle container includes a housing that houses a microneedle and a cover that covers the microneedle. The microneedle includes a base having a first surface on which a projection is formed and a second surface supported by a supporting portion of the housing. The base has an abutted portion on the first surface where the projection is not formed, and the cover has an abutment portion that faces the abutted portion, and a facing portion that faces the projection. A distance between the abutment portion and the facing portion is larger than that between the abutted portion and a distal end of the projection in a direction in which the projection extends. A distance between the abutment portion and the supporting portion is smaller than a sum of a distance between the abutted portion and the second surface and a distance between the abutted portion and the distal end.

公开(公告)号：US20160082626A1

公开(公告)日：2016-03-24

申请号：US14958691

申请日：2015-12-03

Applicant: TOPPAN PRINTING CO., LTD.

Inventor： Hiroyuki KATO ,  Hanae Tagami ,  Hisami Ueno ,  Seiji Gunjima ,  Hiroshi Matsuzawa ,  Momoko Araki ,  Shigeki Takahata

IPC: B29C43/02 ,  B29C43/36 ,  B29C43/34 ,  B29C43/52

CPC classification number: B29C43/021 ,  A61M37/0015 ,  A61M2037/0046 ,  A61M2037/0053 ,  B29C33/424 ,  B29C39/026 ,  B29C41/045 ,  B29C43/146 ,  B29C43/203 ,  B29C43/34 ,  B29C43/3697 ,  B29C43/52 ,  B29C2043/025 ,  B29C2043/026 ,  B29C2043/3205 ,  B29C2043/3673 ,  B29K2105/0035 ,  B29K2105/0058 ,  B29K2627/12 ,  B29K2683/00 ,  B29K2995/0065 ,  B29L2031/7544 ,  B29L2031/756

Abstract: A method of manufacturing an acicular body including a support substrate and a needle formed on the support substrate, includes: supplying a needle forming solution onto an intaglio plate having a recess that has a shape corresponding to the needle; disposing a film on the needle forming solution; compressing the needle forming solution from above the film such that the needle forming solution is moved into the recess; and removing a liquid component from the needle forming solution inside the recess such that the needle forming solution is solidified and that the needle is formed.

Abstract translation: 一种制造针状体的方法，所述针状体包括支撑基板和形成在所述支撑基板上的针，包括：将针状溶液供应到具有与针相对应的形状的凹部的凹版上; 在成针溶液上涂膜; 从膜上方压制针形成溶液，使得针形溶液移入凹槽中; 并且从所述凹部内的针形成溶液中除去液体成分，使得针状溶液固化并形成针。

公开(公告)号：US10702687B2

公开(公告)日：2020-07-07

申请号：US15416093

申请日：2017-01-26

Applicant: TOPPAN PRINTING CO., LTD.

Inventor： Hisami Ueno

IPC: A61M37/00

Abstract: A microneedle unit including a microneedle including a substrate having a first surface and a second surface opposite to the first surface, the microneedle further including a projection protruding from the first surface of the substrate, an adhesive sheet including a sticking region attached to the second surface, the adhesive sheet further including an adhesive region protruding outside the substrate from the sticking region in a direction parallel to the second surface, and a protective sheet covering a portion of the adhesive region outside of the substrate in the direction parallel to the second surface.

公开(公告)号：US20180126139A1

公开(公告)日：2018-05-10

申请号：US15865925

申请日：2018-01-09

Applicant: TOPPAN PRINTING CO., LTD.

Inventor： Hisami Ueno

IPC: A61M37/00

CPC classification number: A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0046 ,  A61M2037/0053 ,  A61M2037/0061

Abstract: A transdermal administration device includes an administration section which includes a substrate having a first surface and a second surface which is a surface opposite to the first surface, and a projection protruding from the first surface, the administration section having flexibility; and a support body having a support surface that supports the second surface, the support body having flexibility. The support body includes at least one low rigidity region and at least one high rigidity region having flexural rigidity higher than flexural rigidity of the low rigidity region, the support body being configured to satisfy at least one of requirements that the low rigidity region is sandwiched by two high rigidity regions to form a stripe and that the high rigidity region is sandwiched by two low rigidity regions to form a stripe.

公开(公告)号：US20180078513A1

公开(公告)日：2018-03-22

申请号：US15825618

申请日：2017-11-29

Applicant: TOPPAN PRINTING CO., LTD.

Inventor： Hisami Ueno

IPC: A61K9/70

CPC classification number: A61K9/7084 ,  A61K9/0021 ,  A61K9/7038 ,  A61K9/7092 ,  A61M5/14248 ,  A61M37/00 ,  A61M37/0015 ,  A61M2037/0023 ,  A61M2037/003

Abstract: A transdermal administration device includes: a substrate having a first surface and a second surface opposite to the first surface; a plurality of projections protruding from the first surface of the substrate, the plurality of projections being provided for piercing an administration target; and a raised and/or recessed structure composed of a plurality of raised and/or recessed elements. The plurality of raised and/or recessed elements includes at least either of raised elements raised from the second surface or recessed elements recessed from the second surface. The substrate, the projections and the raised and/or recessed structure are made of transparent material, and the plurality of raised and/or recessed elements forms a pattern as viewed in a direction perpendicular to the second surface which is finer than a pattern formed by the plurality of projections as viewed in a direction perpendicular to the first surface.