摘要:
The present invention relates to an information input system and method using an extension key. The information input system comprises: an input unit including a plurality of divided regions, for detecting a user selected divided region among the plurality of divided regions; and an input analysis unit for allocating corresponding information to the plurality of divided regions, and analyzing, if the input unit detects a user selected divided region among the plurality of divided regions, whether or not information allocated to the divided region is input. The input analysis unit allocates an extension key to at least one divided region out of the plurality of divided regions; and once the extension key is selected, the input analysis unit allocates new information to an extended region which is a divided region determined according to the extension key.
摘要:
The present invention brings the easiness in the input of non-vocabulary phrase and sentence by applying the disambiguation input method used as a predictive input method for words in English-speaking countries to non-vocabulary phrases and sentences including not only characters but also ‘space’ and symbols.
摘要:
A virtual keyboard input system using a pointing device in a digital device. The virtual keyboard input system includes: a sensor unit sensing a contact and a two-dimensional contact position; a switch unit; and a control unit dividing a contact sensitive region of the sensor unit into multiple division regions according to XY coordinates, assigning virtual keys of a virtual keyboard to the division regions, and when the switch unit is turned on, controlling an input of information for a virtual key assigned to a division region which is contacted among the division regions.
摘要:
Provided are a hybrid of a poorly soluble basic drug and a layered silicate, including a water-soluble basic polymer, and a method of preparing the same. The water-soluble basic polymer may be an aminoalkylmethacrylate copolymer (e.g., Eudragit E 100: a copolymer composed of 1:2:1 ratio of butyl methacrylate, (2,2-dimethylaminoethyl)methacrylate, and methyl methacrylate, Degussa) or polyvinylacetal diethylaminoacetate (AEA). In an oral formulation including the hybrid, a short-term dissolution of the poorly soluble drug can be increased to 90%, thereby increasing drug bioavailability.
摘要翻译:提供了一种难溶性碱性药物和层状硅酸盐,包括水溶性碱性聚合物的混合物及其制备方法。 水溶性碱性聚合物可以是甲基丙烯酸氨基烷基酯共聚物(例如,Eudragit E 100:由甲基丙烯酸丁酯,(2,2-二甲基氨基乙基)甲基丙烯酸酯和甲基丙烯酸甲酯,Degussa的比例为1:2:1的聚合物)或聚乙烯醇缩二乙基氨基乙酸酯 (AEA)。 在包含杂交体的口服制剂中,难溶性药物的短期溶解可以提高到90%,从而提高药物生物利用度。
摘要:
The present invention provides the hybrids wherein itraconazole, cyclosporine or carvedilol are intercalated into the interlayers and/or absorbed onto the surfaces of layered silicates. The hybrids according to the present invention enable the maximization of bioavailability of drugs by dissolving the drugs from the layered silicates. Furthermore, the present invention provides the preparing methods of the hybrids. The process comprises: (1) dispersing a layered silicate in an aqueous solution to form an aqueous solution containing the layered silicate; (2) dissolving a drug in a organic solvent to form an organic solution containing the drug, the organic solvent having a solubility higher than that in the aqueous solution; and (3) mixing and hybridizing in the inerrface of the aqueous solution containing the layered silicate and the organic phase solution containing the drug in order to intercalate the drug into the interlayers of the layered silicate and/or to absorb the drug onto the surface of the layered silicate.
摘要:
Provided is an injectable drug carrier including a non-toxic Layered Double Hydroxide (LDH) and pharmaceutically acceptable excipients. Provided is also a method of preparing the injectable drug carrier, the method including: synthesizing LDH with various compositions and controlling the size and shape of the LDH at a level that the LDH has no adverse effect in vivo. A solution obtained by dispersing the LDH in a solvent is injected in vivo. According to the method, nano-size LDH that does not affect a blood vessel in vivo can be synthesized. The LDH thus synthesized has no adverse effect in vivo even at a concentration of 400 mg/kg, and thus can contribute to establishment of a drug delivery system capable of improving the delivery efficiency of a specific drug.
摘要:
Provided is an injectable drug carrier including a non-toxic Layered Double Hydroxide (LDH) and pharmaceutically acceptable excipients. Provided is also a method of preparing the injectable drug carrier, the method including: synthesizing LDH with various compositions and controlling the size and shape of the LDH at a level that the LDH has no adverse effect in vivo. A solution obtained by dispersing the LDH in a solvent is injected in vivo. According to the method, nano-size LDH that does not affect a blood vessel in vivo can be synthesized. The LDH thus synthesized has no adverse effect in vivo even at a concentration of 400 mg/kg, and thus can contribute to establishment of a drug delivery system capable of improving the delivery efficiency of a specific drug.
摘要:
Provided is a pharmaceutical composition for the treatment of liver cancer, including a layered metal hydroxide-retinoic acid (LMH-RA) hybrid as a novel drug delivery system which shows few side effects of retinoic acid, good drug stability, sustained drug release, and improved drug delivery efficiency.