公开(公告)号：US20120165651A1

公开(公告)日：2012-06-28

申请号：US13257526

申请日：2009-03-23

申请人： Taiga Yamaya ,  Eiji Yoshida ,  Fumihiko Nishikido ,  Taku Inaniwa ,  Hideo Murayama

发明人： Taiga Yamaya ,  Eiji Yoshida ,  Fumihiko Nishikido ,  Taku Inaniwa ,  Hideo Murayama

IPC分类号： A61B6/00

CPC分类号： A61N5/1049 ,  A61B6/037 ,  A61N2005/1052 ,  A61N2005/1087 ,  G01T1/1603 ,  G01T1/2985

摘要： An imaging device, or a PET device, opposed gamma camera type PET device, or open PET device in particular, that is combined with a radiation therapy device, in which detectors are rotated to reduce incidence of nuclear fragments on the detectors. For example, in an opposed gamma camera type PET device, beam irradiation and detector rotation can be synchronized to prevent the detectors from interfering with the treatment beam and reduce the incidence of nuclear fragments on the detectors. This makes it possible to reduce the incidence of nuclear fragments on the detectors without interfering with a treatment beam, thereby enabling measurement of annihilation radiations and three-dimensional imaging of the irradiation field immediately after irradiation or during irradiation.

摘要翻译： 与成像装置或PET装置相对的γ相机型PET装置或特别是开放的PET装置，其与辐射治疗装置组合，其中检测器被旋转以减少检测器上的核碎片的发生率。 例如，在相对的γ照相机类型的PET装置中，可以同步束照射和检测器旋转，以防止检测器干扰处理束并减少检测器上核碎片的发生。 这使得可以在不干扰处理束的情况下降低检测器上核碎片的发生率，从而能够在照射后或照射期间立即测量湮灭辐射和照射场的三维成像。

公开(公告)号：US20120150018A1

公开(公告)日：2012-06-14

申请号：US13257434

申请日：2009-03-23

申请人： Taiga Yamaya ,  Taku Inaniwa ,  Fumihiko Nishikido ,  Hideo Murayama

发明人： Taiga Yamaya ,  Taku Inaniwa ,  Fumihiko Nishikido ,  Hideo Murayama

IPC分类号： A61B5/055 ,  A61B6/00

CPC分类号： A61N5/1049 ,  A61B6/037 ,  A61N2005/1052 ,  A61N2005/1054 ,  A61N2005/1087 ,  G01T1/2985

摘要： A shielding structure against nuclear fragments (referred to as a shield) is operated according to ON and OFF of beam irradiation so as to reduce incidence of nuclear fragments on detectors during beam irradiation. This enables measurement of annihilation radiations and three-dimensional imaging of the irradiation field immediately after irradiation or even during irradiation.

摘要翻译： 根据光束照射的ON和OFF操作针对核碎片的屏蔽结构（称为屏蔽），以减少光束照射期间检测器上核碎片的发生。 这使得能够在照射之后或甚至在照射期间测量湮灭辐射和照射场的三维成像。

公开(公告)号：US08461539B2

公开(公告)日：2013-06-11

申请号：US12996471

申请日：2008-08-01

申请人： Taiga Yamaya ,  Hideo Murayama ,  Taku Inaniwa

发明人： Taiga Yamaya ,  Hideo Murayama ,  Taku Inaniwa

IPC分类号： G01T1/166

CPC分类号： G01T1/2985 ,  A61B6/037 ,  A61B6/583 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1087

摘要： A combined radiation therapy/PET apparatus includes: an open PET device having multi-ring detector rings that are opposed to each other in the direction of the body axis so as to leave a gap therebetween; and a radiation therapy apparatus for performing radiation therapy through the gap. When imaging the condition of an affected area and a treatment beam for monitoring in radiation therapy of irradiating the affected area with X-rays, gamma rays, or particle beams, the apparatus covers a region of interest in the irradiation field of the radiation therapy with the field-of-view of the open PET device, thereby making possible the positioning of the irradiation field and treatment monitoring using PET images.

摘要翻译： 组合放射治疗/ PET装置包括：开放式PET装置，其具有多个环形探测器环，所述多环检测器环在体轴方向上彼此相对以在其间留有间隙; 以及用于通过间隙进行放射治疗的放射线治疗装置。 当对X射线，γ射线或粒子束照射受影响的区域进行辐射治疗的受影响区域状况和治疗束进行成像时，该装置覆盖放射治疗的照射场中的感兴趣区域， 开放的PET装置的视野，从而可以定位照射场和使用PET图像的处理监视。

公开(公告)号：US20110092814A1

公开(公告)日：2011-04-21

申请号：US12996471

申请日：2008-08-01

申请人： Taiga Yamaya ,  Hideo Murayama ,  Taku Inaniwa

发明人： Taiga Yamaya ,  Hideo Murayama ,  Taku Inaniwa

IPC分类号： A61B6/00

CPC分类号： G01T1/2985 ,  A61B6/037 ,  A61B6/583 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1087

摘要： A combined radiation therapy/PET apparatus includes: an open PET device having multi-ring detector rings that are opposed to each other in the direction of the body axis so as to leave a gap therebetween; and a radiation therapy apparatus for performing radiation therapy through the gap. When imaging the condition of an affected area and a treatment beam for monitoring in radiation therapy of irradiating the affected area with X-rays, gamma rays, or particle beams, the apparatus covers a region of interest in the irradiation field of the radiation therapy with the field-of-view of the open PET device, thereby making possible the positioning of the irradiation field and treatment monitoring using PET images.

摘要翻译： 组合放射治疗/ PET装置包括：开放式PET装置，其具有多个环形探测器环，所述多环检测器环在体轴方向上彼此相对以在其间留有间隙; 以及用于通过间隙进行放射治疗的放射线治疗装置。 当对X射线，γ射线或粒子束照射受影响的区域进行辐射治疗的受影响区域状况和治疗束进行成像时，该装置覆盖放射治疗的照射场中的感兴趣区域， 开放的PET装置的视野，从而可以定位照射场和使用PET图像的处理监视。

公开(公告)号：US08581196B2

公开(公告)日：2013-11-12

申请号：US12996443

申请日：2008-08-01

申请人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara ,  Taku Inaniwa ,  Takuji Furukawa ,  Shinichirou Mori

发明人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara ,  Taku Inaniwa ,  Takuji Furukawa ,  Shinichirou Mori

IPC分类号： G01T1/161

CPC分类号： G01T1/2985 ,  A61B6/037 ,  A61B6/4266 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1087

摘要： In beam monitoring for detecting annihilation radiations produced by radiation irradiation in radiation therapy for cancer which is performed by irradiating the affected area by X-rays, gamma rays, or particle beams, a detector-shift type combined radiation therapy/PET apparatus is provided with an open PET device that includes a plurality of shiftable multi-ring detector rings; and a radiation irradiation device that is capable of irradiation with a radiation beam through between the detector rings. The apparatus changes the positions of the detector rings, performs irradiation with the radiation beam through between the detector rings, and then performs radiation measurement.

摘要翻译： 在通过用X射线，γ射线或粒子束照射受影响区域进行的用于检测通过放射治疗癌症的放射线照射产生的湮灭辐射的光束监测中，提供了检测器移位型组合放射治疗/ PET装置 一种开放的PET装置，包括多个可移动的多环检测器环; 以及能够通过检测器环之间的辐射束照射的放射线照射装置。 该装置改变检测器环的位置，通过检测器环之间的辐射束进行照射，然后执行辐射测量。

公开(公告)号：US20110084211A1

公开(公告)日：2011-04-14

申请号：US12996443

申请日：2008-08-01

申请人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara ,  Taku Inaniwa ,  Takuji Furukawa ,  Shinichirou Mori

发明人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara ,  Taku Inaniwa ,  Takuji Furukawa ,  Shinichirou Mori

IPC分类号： G01T1/161 ,  A61N5/10

CPC分类号： G01T1/2985 ,  A61B6/037 ,  A61B6/4266 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1087

摘要： In beam monitoring for detecting annihilation radiations produced by radiation irradiation in radiation therapy for cancer which is performed by irradiating the affected area by X-rays, gamma rays, or particle beams, a detector-shift type combined radiation therapy/PET apparatus is provided with an open PET device that includes a plurality of shiftable multi-ring detector rings; and a radiation irradiation device that is capable of irradiation with a radiation beam through between the detector rings. The apparatus changes the positions of the detector rings, performs irradiation with the radiation beam through between the detector rings, and then performs radiation measurement.

摘要翻译： 在通过用X射线，γ射线或粒子束照射受影响区域进行的用于检测通过放射治疗癌症的放射线照射产生的湮灭辐射的光束监测中，提供了检测器移位型组合放射治疗/ PET装置 一种开放的PET装置，包括多个可移动的多环检测器环; 以及能够通过检测器环之间的辐射束照射的放射线照射装置。 该装置改变检测器环的位置，通过检测器环之间的辐射束进行照射，然后执行辐射测量。

公开(公告)号：US08487282B2

公开(公告)日：2013-07-16

申请号：US13577509

申请日：2011-02-07

申请人： Yasushi Iseki ,  Katsushi Hanawa ,  Kazunao Maeda ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

发明人： Yasushi Iseki ,  Katsushi Hanawa ,  Kazunao Maeda ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

IPC分类号： A61N5/10

CPC分类号： A61N5/10 ,  A61N5/1043 ,  A61N5/1075 ,  A61N2005/1074 ,  A61N2005/1087 ,  G01T1/2935

摘要： A particle beam irradiation apparatus that can measure and display a dose two-dimensional distribution during scan while reducing degradation of a particle beam shape, including a particle beam generation portion; a particle beam emission control portion; a two-dimensional beam scanning portion; a sensor portion including first linear electrodes arranged in parallel in a first direction and second linear electrodes arranged in parallel in a second direction orthogonal to the first direction; a beam shape calculation portion that calculates a center of gravity of the particle beam from outputs of each the first linear and second linear electrodes and that obtains a two-dimensional beam shape of the particle beam around the center of gravity; a storage portion that accumulates and stores the two-dimensional beam shapes; and a display portion that displays the two-dimensional beam shapes as a two-dimensional distribution of a dose.

摘要翻译： 一种粒子束照射装置，其能够在扫描期间测量并显示剂量二维分布，同时减少包括粒子束产生部分在内的粒子束形状的退化; 粒子束发射控制部分; 二维光束扫描部分; 传感器部分包括沿第一方向平行布置的第一线性电极和沿与第一方向正交的第二方向平行布置的第二线性电极; 束形状计算部，其从所述第一线状电极和所述第二线状电极的输出计算所述粒子束的重心，并且获得所述粒子束围绕所述重心的二维束形状; 存储部，其积存并存储二维光束形状; 以及显示部，其将二维光束形状显示为剂量的二维分布。

公开(公告)号：US20120305790A1

公开(公告)日：2012-12-06

申请号：US13577741

申请日：2011-02-07

申请人： Katsushi Hanawa ,  Yasushi Iseki ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

发明人： Katsushi Hanawa ,  Yasushi Iseki ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

IPC分类号： A61N5/10

CPC分类号： A61N5/1043 ,  A61N5/1071 ,  A61N2005/1074 ,  A61N2005/1087 ,  G21K1/025

摘要： Provided is a particle beam irradiation apparatus capable of highly reliable measurement of a dose of each beam and capable of highly sensitive measurement of a leakage dose caused by momentary beam emission. The particle beam irradiation apparatus according to the present invention includes: an emission control portion that controls emission and termination of a particle beam; a control portion that sequentially changes an irradiation position of the particle beam relative to an affected area; first and second dosimeters that measure dose rates of the particle beam directed to the affected area; and an abnormality determination portion that accumulates the dose rates output from the first and second dosimeters for each of predetermined determination periods to calculate first and second sectional dose measurement values and that performs second abnormality determination of determining that there is an abnormality and outputs an interlock signal for terminating the emission of the particle beam in at least one of a case in which the first sectional dose measurement value exceeds a predetermined first reference range and a case in which the second sectional dose measurement value exceeds a predetermined second reference range.

摘要翻译： 提供一种能够高度可靠地测量每个光束的剂量并且能够高度敏感地测量由瞬时光束发射引起的泄漏剂量的粒子束照射装置。 根据本发明的粒子束照射装置包括：发射控制部分，其控制粒子束的发射和终止; 控制部，其依次改变所述粒子束相对于受影响区域的照射位置; 测量指向受影响区域的粒子束的剂量率的第一和第二剂量计; 以及异常判定部，其对于每个规定的判定期间累积从第一和第二剂量计输出的剂量率，以计算第一和第二截面剂量测量值，并且执行确定存在异常的第二异常判定并输出互锁信号 用于在第一部分剂量测量值超过预定的第一参考范围的情况和第二部分剂量测量值超过预定的第二参考范围的情况中的至少一个中终止粒子束的发射。

公开(公告)号：US08552408B2

公开(公告)日：2013-10-08

申请号：US13577741

申请日：2011-02-07

申请人： Katsushi Hanawa ,  Yasushi Iseki ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

发明人： Katsushi Hanawa ,  Yasushi Iseki ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

IPC分类号： A61N5/10

CPC分类号： A61N5/1043 ,  A61N5/1071 ,  A61N2005/1074 ,  A61N2005/1087 ,  G21K1/025

摘要： Provided is a particle beam irradiation apparatus capable of highly reliable measurement of a dose of each beam and capable of highly sensitive measurement of a leakage dose caused by momentary beam emission. The particle beam irradiation apparatus according to the present invention includes: an emission control portion that controls emission and termination of a particle beam; a control portion that sequentially changes an irradiation position of the particle beam relative to an affected area; first and second dosimeters that measure dose rates of the particle beam directed to the affected area; and an abnormality determination portion that accumulates the dose rates output from the first and second dosimeters for each of predetermined determination periods to calculate first and second sectional dose measurement values and that performs second abnormality determination of determining that there is an abnormality and outputs an interlock signal for terminating the emission of the particle beam in at least one of a case in which the first sectional dose measurement value exceeds a predetermined first reference range and a case in which the second sectional dose measurement value exceeds a predetermined second reference range.

摘要翻译： 提供一种能够高度可靠地测量每个光束的剂量并且能够高度敏感地测量由瞬时光束发射引起的泄漏剂量的粒子束照射装置。 根据本发明的粒子束照射装置包括：发射控制部分，其控制粒子束的发射和终止; 控制部，其依次改变所述粒子束相对于受影响区域的照射位置; 测量指向受影响区域的粒子束的剂量率的第一和第二剂量计; 以及异常判定部，其对于每个规定的判定期间累积从第一和第二剂量计输出的剂量率，以计算第一和第二截面剂量测量值，并且执行确定存在异常的第二异常判定并输出互锁信号 用于在第一部分剂量测量值超过预定的第一参考范围的情况和第二部分剂量测量值超过预定的第二参考范围的情况中的至少一个中终止粒子束的发射。

公开(公告)号：US20120305796A1

公开(公告)日：2012-12-06

申请号：US13577509

申请日：2011-02-07

申请人： Yasushi Iseki ,  Katsushi Hanawa ,  Kazunao Maeda ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

发明人： Yasushi Iseki ,  Katsushi Hanawa ,  Kazunao Maeda ,  Nobukazu Kakutani ,  Takuji Furukawa ,  Taku Inaniwa ,  Shinji Sato ,  Kouji Noda

IPC分类号： A61N5/10 ,  G21K5/04

CPC分类号： A61N5/10 ,  A61N5/1043 ,  A61N5/1075 ,  A61N2005/1074 ,  A61N2005/1087 ,  G01T1/2935

摘要： Provided is a particle beam irradiation apparatus that can measure and display a dose two-dimensional distribution during scan with a simple configuration, while reducing degradation of a particle beam shape. The particle beam irradiation apparatus according to the present invention includes: a beam generation portion that generates a particle beam; a beam emission control portion that controls emission of the particle beam; a beam scanning portion that two-dimensionally scans the particle beam; a sensor portion including a plurality of first linear electrodes arranged in parallel in a first direction and a plurality of second linear electrodes arranged in parallel in a second direction orthogonal to the first direction; a beam shape calculation portion that calculates a center of gravity of the particle beam from a first signal output from each of the first linear electrodes and a second signal output from each of the second linear electrodes and that obtains a two-dimensional beam shape of the particle beam around the center of gravity; a storage portion that accumulates and stores the two-dimensional beam shapes; and a display portion that displays the two-dimensional beam shapes as a two-dimensional distribution of a dose.

摘要翻译： 提供一种粒子束照射装置，其能够以简单的构造在扫描期间测量和显示剂量二维分布，同时减少粒子束形状的劣化。 根据本发明的粒子束照射装置包括：产生粒子束的光束产生部; 控制粒子束发射的光束发射控制部分; 二维地扫描粒子束的光束扫描部; 传感器部分，包括沿第一方向平行布置的多个第一线性电极和沿与第一方向正交的第二方向平行设置的多个第二线性电极; 光束形状计算部分，其根据从每个第一线性电极输出的第一信号和从每个第二线性电极输出的第二信号计算粒子束的重心，并且获得二维波束形状 颗粒束围绕重心; 存储部，其积存并存储二维光束形状; 以及显示部，其将二维光束形状显示为剂量的二维分布。