公开(公告)号：US08257755B2

公开(公告)日：2012-09-04

申请号：US11795638

申请日：2006-01-20

申请人： Takao Sasaki ,  Masamichi Yano

发明人： Takao Sasaki ,  Masamichi Yano

IPC分类号： A61K36/752 ,  A61K31/235

CPC分类号： A61K36/752 ,  A23L33/105 ,  A61K31/37

摘要： A metabolic syndrome relieving agent that is free from a problem of side effects and can be taken for a long term is provided. Bergamottin is used as an agent for relieving a metabolic syndrome. Since bergamottin has functions of activating PPARα and PPARγ, promoting the secretion of adiponectin in adipocytes and inhibiting the generation of VLDLs in hepatic cells, it is possible to prevent or treat diseases such as insulin resistance, hyperinsulinism, type 2 diabetes, obesity, visceral fat obesity, hypertension, hyperlipemia, arteriosclerosis and the like and thus prevent or treat the metabolic syndrome. Also, as understood from the fact that citrus fruits such as a grapefruit or the like containing bergamottin have been eaten for many years, they have no problems in terms of safety and have a low calorie content, and therefore, they can be taken for a long term. Further, since bergamottin is tasteless and odorless, it does not impair the unique taste of a food when added to this food, so that it can be added to foods and taken.

摘要翻译： 提供了不存在副作用问题并可长期服用的代谢综合征缓解剂。 使用博加莫汀作为缓解代谢综合征的药物。 由于bergamottin具有激活PPARα和PPARγ的功能，促进脂肪细胞中脂联素的分泌和抑制肝细胞中VLDL的产生，可以预防或治疗诸如胰岛素抵抗，胰岛素抵抗，2型糖尿病，肥胖，内脏脂肪 肥胖症，高血压，高脂血症，动脉硬化等，从而预防或治疗代谢综合征。 另外，由于柑橘类水果例如葡萄柚等含有万古霉素已被吃掉多年，因此在安全性方面没有问题，并且卡路里含量低，因此可以将其用于 长期。 此外，由于香柠檬醇是无味无味的，因此当添加到食物中时，它不会损害食物的独特味道，从而可以将其加入到食物中并服用。

公开(公告)号：US20080132566A1

公开(公告)日：2008-06-05

申请号：US11795638

申请日：2006-01-20

申请人： Takao Sasaki ,  Masamichi Yano

发明人： Takao Sasaki ,  Masamichi Yano

IPC分类号： A61K31/352 ,  C07D493/02 ,  A61P3/00

CPC分类号： A61K36/752 ,  A23L33/105 ,  A61K31/37

摘要： A metabolic syndrome relieving agent that is free from a problem of side effects and can be taken for a long term is provided. Bergamottin is used as an agent for relieving a metabolic syndrome. Since bergamottin has functions of activating PPARα and PPARγ, promoting the secretion of adiponectin in adipocytes and inhibiting the generation of VLDLs in hepatic cells, it is possible to prevent or treat diseases such as insulin resistance, hyperinsulinism, type 2 diabetes, obesity, visceral fat obesity, hypertension, hyperlipemia, arteriosclerosis and the like and thus prevent or treat the metabolic syndrome. Also, as understood from the fact that citrus fruits such as a grapefruit or the like containing bergamottin have been eaten for many years, they have no problems in terms of safety and have a low calorie content, and therefore, they can be taken for a long term. Further, since bergamottin is tasteless and odorless, it does not impair the unique taste of a food when added to this food, so that it can be added to foods and taken.

摘要翻译： 提供了不存在副作用问题并可长期服用的代谢综合征缓解剂。 使用博加莫汀作为缓解代谢综合征的药物。 由于bergamottin具有激活PPARα和PPARγ的功能，促进脂肪细胞中脂联素的分泌和抑制肝细胞中VLDL的产生，可以预防或治疗诸如胰岛素抵抗，胰岛素抵抗，2型糖尿病，肥胖，内脏脂肪 肥胖症，高血压，高脂血症，动脉硬化等，从而预防或治疗代谢综合征。 另外，由于柑橘类水果例如葡萄柚等含有万古霉素已被吃掉多年，因此在安全性方面没有问题，并且卡路里含量低，因此可以将其用于 长期。 此外，由于香柠檬醇是无味无味的，因此当添加到食物中时，它不会损害食物的独特味道，从而可以将其加入到食物中并服用。

公开(公告)号：US07373788B2

公开(公告)日：2008-05-20

申请号：US11127218

申请日：2005-05-12

申请人： Kazuto Kobayashi ,  Eiji Fukuda ,  Kazuhiko Watanabe ,  Masamichi Yano ,  Makoto Sudo

发明人： Kazuto Kobayashi ,  Eiji Fukuda ,  Kazuhiko Watanabe ,  Masamichi Yano ,  Makoto Sudo

IPC分类号： F25D19/00 ,  F25B41/06

CPC分类号： F25B41/062 ,  F16K31/002 ,  F25B2341/0683 ,  F25B2500/13 ,  F25B2500/21

摘要： An expansion valve includes a valve body having a valve body hole, a first passage, a bottomed valve chamber, a second passage, a third passage and a guide member disposed in the valve body hole between the first passage and the third passage. The valve body hole has a first valve body hole portion and a second valve body hole portion of different diameters forming a valve body step between the second passage and the first passage. The guide has a first guide portion and a second guide portion of different diameters forming a guide portion step. The guide is sized to be slidably received by the valve body hole in a close-fitting relationship with the first valve body hole portion receiving the first guide portion, the second valve body hole portion receiving the second guide portion and the valve body step and the guide portion step contacting each other.

摘要翻译： 膨胀阀包括具有阀体孔的阀体，设置在第一通道和第三通道之间的阀体孔中的第一通道，有底阀室，第二通道，第三通道和引导构件。 阀体孔具有形成在第二通道和第一通道之间的阀体台阶的不同直径的第一阀体孔部分和第二阀体孔部分。 引导件具有不同直径的第一引导部分和第二引导部分，形成引导部分步骤。 引导件的尺寸设计成可以与容纳第一引导部分的第一阀体孔部分接近的阀体孔可靠地接合，第二阀体孔部分接纳第二引导部分和阀体步骤， 引导部分步骤彼此接触。

公开(公告)号：US06896190B2

公开(公告)日：2005-05-24

申请号：US10689052

申请日：2003-10-21

申请人： Kazuto Kobayashi ,  Kazuhiko Watanabe ,  Masamichi Yano

发明人： Kazuto Kobayashi ,  Kazuhiko Watanabe ,  Masamichi Yano

IPC分类号： F16K31/68 ,  B60H1/32 ,  F25B41/06 ,  F25B41/04

CPC分类号： F25B41/062 ,  F25B2341/0683 ,  F25B2500/01 ,  F25B2500/13 ,  F25B2500/17 ,  F25B2500/21 ,  Y10T137/87917 ,  Y10T137/87925

摘要： An expansion valve 1 includes a square rod-shaped valve body 10. A first path 20 into which refrigerant is introduced, a valve chamber 22 formed near the bottom of the path, a second path 24 for refrigerant heading toward an evaporator and a third path 26 for refrigerant returning from the evaporator are provided to the valve body 10. A valve member 30 provided inside the valve chamber is operated by a power element 70 via an actuating rod 60. In order to assemble the expansion valve, an assembled orifice member 40 and an assembled guide member 100 are press-fitted into an opening provided to the valve body 10.

摘要翻译： 膨胀阀1包括方棒形阀体10。 制冷剂被引入的第一路径20，形成在路径底部附近的阀室22，用于朝向蒸发器的制冷剂的第二路径24和用于从蒸发器返回的制冷剂的第三路径26设置在阀体10上 。 设置在阀室内部的阀构件30由动力元件70经由致动杆60操作。 为了组装膨胀阀，组装的孔元件40和组装的引导构件100被压配合到设置在阀体10上的开口中。

公开(公告)号：US06293472B1

公开(公告)日：2001-09-25

申请号：US09179885

申请日：1998-10-28

申请人： Masamichi Yano

发明人： Masamichi Yano

IPC分类号： F25B4104

CPC分类号： F25B41/062 ,  F25B2341/0683 ,  F25B2500/01

摘要： A power element portion 36′ mounted on the upper portion of an expansion valve body comprises an upper cover 36d and a lower cover 36h, and is divided into an upper pressure chamber 36b and a lower pressure chamber 36c by a diaphragm 36a. A heat sensing drive shaft 101 is formed of a large radius portion 105 and a heat conducting shaft 103 integrally formed thereto. The stopper portion 104 contacting the lower surface of the diaphragm 36a is a member which is formed separately from the heat sensing drive shaft 101, and supported within the lower cover 36h. When the expansion valve is taken apart, the heat sensing drive shaft 101 is pulled out from the inside of the mounting seat 362 of the power element portion 36′, and the refrigerant remaining inside the upper pressure chamber 36b is taken out and collected from the side of the diaphragm.

摘要翻译： 安装在膨胀阀体的上部的动力元件部分36'包括上盖36d和下盖36h，并通过隔膜36a分成上压力室36b和下压力室36c。 热传感驱动轴101由与其一体形成的大径部105和导热轴103形成。 与隔膜36a的下表面接触的止动部104是与感热驱动轴101分开形成并支承在下罩36h内的部件。 当膨胀阀分离时，热传感驱动轴101从动力元件部分36'的安装座362的内部被拉出，并且从上压力室36b内残留的制冷剂从 隔膜的一侧

公开(公告)号：US6164624A

公开(公告)日：2000-12-26

申请号：US554718

申请日：1995-11-07

申请人： Kazuhiko Watanabe ,  Masamichi Yano

发明人： Kazuhiko Watanabe ,  Masamichi Yano

IPC分类号： F16K31/68 ,  F16K1/42 ,  F16K25/04 ,  F25B1/00 ,  F25B41/06 ,  F16K31/00 ,  G05D27/00

CPC分类号： F25B41/062 ,  F16K1/422 ,  F16K25/04 ,  F25B2341/0683 ,  F25B2500/01

摘要： An expansion valve comprises an orifice formed in a valve body and a valve member fixed to a movable member. Movement of a diaphragm is transmitted to an actuating rod via a member and the actuating rod actuated the movable member to control the opening amount of the path between the valve member and the orifice. An orifice member affixed to the orifice is made of a material harder than the valve body, and free from erosion or other damage by a refrigerant, which will otherwise occur at the valve opening portion.

摘要翻译： 膨胀阀包括形成在阀体中的孔口和固定到可动构件的阀构件。 隔膜的运动经由构件传递到致动杆，并且致动杆致动可动构件以控制阀构件和孔口之间的路径的打开量。 固定在孔口上的孔口部件由比阀体更硬的材料制成，并且不受制冷剂的侵蚀或其它损坏，否则会在阀开口部分产生。

公开(公告)号：US5799499A

公开(公告)日：1998-09-01

申请号：US651538

申请日：1996-05-22

申请人： Masamichi Yano ,  Takuji Furuta

发明人： Masamichi Yano ,  Takuji Furuta

IPC分类号： F25B1/00 ,  F25B41/06 ,  F25B43/00 ,  F25B41/04

CPC分类号： F25B41/062 ,  F25B43/006 ,  F25B2341/0683 ,  F25B2500/18 ,  F25B2500/21 ,  F25B43/003

摘要： A unit incorporating a reservoir tank and an expansion valve into a single built-in structure comprises a reservoir tank 10 sealed by a cover 20, and an expansion valve 30 fixed on the cover 20. A refrigerant pipe 40 extending through the cover 20 introduces a refrigerant from a compressor through a condenser into the reservoir tank 10. The refrigerant introduced into the expansion valve 30 through a pipe 50 increases in volume, and then enters an evaporator. After passing the evaporator, the refrigerant in the gaseous phase flows through pipe 62 into the expansion valve 30, then delivers thermal information of the refrigerant to a heat sensitive member of the expansion valve, and travels in a pipe 70 extending into and from the reservoir tank 10. While traveling along the pipe 70, the gaseous refrigerant exchanges heat with the liquid refrigerant stored in the reservoir tank, and then returns to the compressor.

摘要翻译： 将储罐和膨胀阀结合到单个内置结构中的单元包括由盖20密封的储存罐10和固定在盖20上的膨胀阀30.延伸穿过盖20的制冷剂管40引入 制冷剂从压缩机通过冷凝器进入储存罐10.通过管道50引入膨胀阀30的制冷剂体积增加，然后进入蒸发器。 在通过蒸发器之后，气相中的制冷剂通过管62流入膨胀阀30，然后将制冷剂的热信息传递到膨胀阀的热敏元件，并且在延伸进入和从储存器的管道70中行进 在沿着管70行进的同时，气体制冷剂与储存在储液罐中的液体制冷剂进行热交换，然后返回压缩机。

公开(公告)号：US07299995B2

公开(公告)日：2007-11-27

申请号：US10797106

申请日：2004-03-11

申请人： Daisuke Watari ,  Masamichi Yano

发明人： Daisuke Watari ,  Masamichi Yano

IPC分类号： F25B41/04

CPC分类号： F25B41/062 ,  F25B2500/12

摘要： The body of a valve has an orifice that internally connects a high-pressure passage through which a refrigerant flows in and a low-pressure passage through which the refrigerant flows out. The valve includes a valve plug for adjusting the flow rate of the refrigerant flowing in the orifice, an operating rod for moving the valve plug in a valve opening direction, and a temperature sensing drive unit for driving the operating rod. A support ring for constraining the spherical valve plug is located on the upper-stream side of the high-pressure passage with respect to the orifice. The support ring is formed of a circular annular portion capable of elastic deformation and vibration-proof springs. The springs support the valve plug.

摘要翻译： 阀体具有内部连接制冷剂所流过的高压通道和制冷剂流过的低压通道的孔口。 阀包括用于调节在孔中流动的制冷剂的流量的阀塞，用于沿阀打开方向移动阀塞的操作杆和用于驱动操作杆的温度感测驱动单元。 用于约束球形阀塞的支撑环位于高压通道相对于孔口的上游侧。 支撑环由能够弹性变形和防振弹簧的圆形环形部分形成。 弹簧支撑阀塞。

公开(公告)号：US06895993B2

公开(公告)日：2005-05-24

申请号：US10152821

申请日：2002-05-23

申请人： Kazuto Kobayashi ,  Masamichi Yano

发明人： Kazuto Kobayashi ,  Masamichi Yano

IPC分类号： B60H1/32 ,  F16K31/68 ,  F25B41/06 ,  G05D23/02 ,  F16K31/365

CPC分类号： F25B41/062 ,  F25B2341/0683 ,  Y10T137/7504 ,  Y10T137/7668 ,  Y10T137/7737

摘要： An expansion valve 1 comprises a piping member 10 equipped with passages to which refrigerant pipes are connected, and a cassette unit 100, the two members being formed as separate units. The cassette unit 100 comprises a tube member 110 having a flange portion 111, and at the interior of the tube member 110 are fixed a guide member 170, an orifice member 180, and a plate member 166. The pressure of the gas filled in a gas charge chamber 122 defined by a lid 120 and a diaphragm 130 displaces the diaphragm 130, the displacement being transmitted through a stopper member 140 to a shaft member 150. The shaft member 150 is guided by a guide member 170 and controls the valve means 160 inside a valve chamber 161. The cassette unit 100 is inserted to the piping member 10 and fixed to position by a ring 50. Seal members 62, 64, and 66 are equipped to appropriate areas between the cassette unit and the piping member.

摘要翻译： 膨胀阀1包括配备有与制冷剂管连接的通道的管道构件10和两个构件形成为分离单元的盒单元100。 盒单元100包括具有凸缘部分111的管构件110，并且在管构件110的内部固定有引导构件170，孔构件180和板构件166.填充在 由盖120和隔膜130限定的气体充电室122使隔膜130移位，该位移通过止动构件140传递到轴构件150.轴构件150由引导构件170引导并且控制阀装置160 盒单元100插入到管道构件10中并通过环50固定到位置。密封构件62,64和66被配备到盒单元和管道构件之间的适当区域。

公开(公告)号：US06889909B2

公开(公告)日：2005-05-10

申请号：US10614086

申请日：2003-07-08

申请人： Kazuto Kobayashi ,  Masamichi Yano ,  Kazuhiko Watanabe

发明人： Kazuto Kobayashi ,  Masamichi Yano ,  Kazuhiko Watanabe

IPC分类号： F16K31/68 ,  F25B41/06 ,  G05D23/12 ,  F25B41/04

CPC分类号： F25B41/062 ,  F25B2341/0683

摘要： An expansion valve 1 comprises a piping member 10 having passages to which pipes for a refrigerant are connected, and a cassette unit 100, which are formed as separate components. The cassette unit 100 comprises a tube member 110 accommodating a guide member 170, an orifice member 180 and a plate member 166. A diaphragm 130 sandwiched between a rising portion 121 of a lid 120 and an end 110′c of the tube member 110 and defining a gas charge chamber 122 is displaced, the movement of which is transmitted to a shaft member 150. The shaft member 150 is guided by a guide member 170 and drives a valve member 160 disposed within a valve chamber 161. The cassette unit 100 is inserted to the piping member 10 and fixed by a ring 50. Seal members 62, 64, 66 are disposed to necessary areas.

摘要翻译： 膨胀阀1包括管道构件10，管道构件10具有连接用于制冷剂的管道的通道和形成为分离部件的盒单元100。 盒单元100包括容纳引导构件170的管构件110，孔构件180和板构件166。 夹在盖120的上升部分121和管构件110的端部110'c之间并限定气体充注室122的隔膜130移动，其运动被传递到轴构件150。 轴构件150由引导构件170引导并且驱动设置在阀室161内的阀构件160。 盒单元100插入到管道构件10中并通过环50固定。 密封构件62,64,66设置在必要区域。