Percutaneous absorption preparation containing palonosetron
    1.
    发明申请
    Percutaneous absorption preparation containing palonosetron 审中-公开
    含帕洛诺司琼的经皮吸收制剂

    公开(公告)号:US20090285877A1

    公开(公告)日:2009-11-19

    申请号:US12453566

    申请日:2009-05-14

    IPC分类号: A61K9/70 A61K31/473

    摘要: There is provided a percutaneous absorption preparation that has a simple laminated structure and a long shelf life, while maintaining excellent percutaneous absorption for palonosetron. The percutaneous absorption preparation comprises a support and a drug-containing pressure-sensitive adhesive layer formed on at least one side of the support, wherein the drug-containing pressure-sensitive adhesive layer comprises, as essential constituent components, an adhesive base, palonosetron or a pharmaceutically acceptable acid addition salt thereof, and at least one type of fatty alcohol selected from the group consisting of C6-12 straight-chain saturated alcohols, C10-22 straight-chain unsaturated alcohols, C10-22 branched alcohols and C10-15 cyclic alcohols, and the constituent components other than palonosetron or its pharmaceutically acceptable acid addition salt are carboxyl group-free components.

    摘要翻译: 提供了具有简单的层压结构和长的保存期限的经皮吸收制剂,同时保持帕洛诺司琼的优异的经皮吸收。 经皮吸收制剂包括在载体的至少一侧上形成的载体和含药物的压敏粘合剂层,其中药物压敏粘合剂层包含作为必要组分的组分的粘合剂基质,帕洛诺司琼或 其药学上可接受的酸加成盐和至少一种选自C 6-12直链饱和醇,C10-22直链不饱和醇,C10-22支链醇和C10-15环状脂肪醇的脂肪醇 醇,除了帕洛诺司琼或其药学上可接受的酸加成盐以外的组成成分是无羧基组分。

    Electronic device and image forming apparatus
    2.
    发明授权
    Electronic device and image forming apparatus 有权
    电子设备和图像形成装置

    公开(公告)号:US09527321B2

    公开(公告)日:2016-12-27

    申请号:US14728045

    申请日:2015-06-02

    IPC分类号: B41J29/10

    CPC分类号: B41J29/10

    摘要: An electronic device comprises: a shielding object that is arranged at least in a plurality of directions and shields noise; and a Helmholtz silencer that is arranged in a direction where the shielding object does not exist, the shielding object and the silencer being arranged with respect to a noise source causing noise such as a driving source that is arranged inside an apparatus body, wherein a neck portion of the Helmholtz silencer is directed to the noise source, a plurality of such Helmholtz silencers are provided to correspond to at least two kinds of frequencies, and installed number of the Helmholtz silencers corresponding to at least two kinds of the frequencies respectively, is made different depending on a distance from the noise source.

    摘要翻译: 电子设备包括:至少布置在多个方向上并屏蔽噪声的屏蔽物体; 以及亥姆霍兹消声器,其被布置在不存在屏蔽物体的方向上,所述屏蔽物体和所述消声器相对于噪声源被布置,所述噪声源引起设置在设备主体内部的驱动源等噪声,其中颈部 亥姆霍兹消声器的一部分被引导到噪声源,提供多个这样的亥姆霍兹消声器以对应于至少两种频率,并且分别安装与至少两种频率对应的亥姆霍兹消音器的安装数量 根据与噪声源的距离而不同。

    Image forming apparatus
    3.
    发明授权

    公开(公告)号:US11209771B2

    公开(公告)日:2021-12-28

    申请号:US17062844

    申请日:2020-10-05

    IPC分类号: G03G15/00 G03G21/16

    摘要: An image forming apparatus includes an image forming device, a sheet feeder, and a housing. The image forming device forms an image on a recording medium. The sheet feeder stores the recording medium and conveys the recording medium toward the image forming device. The housing accommodates an electrical device in the housing. The housing includes a housing body and a drawer that is drawn out from the housing body. The drawer includes a bottom plate on which the electrical device is placeable and a partition above the bottom plate on which the electrical device is placeable.

    Lock lever structure, unit, and image forming apparatus

    公开(公告)号:US10594880B2

    公开(公告)日:2020-03-17

    申请号:US15369452

    申请日:2016-12-05

    IPC分类号: H04N1/00 E05B65/00

    摘要: A lock lever structure includes a shaft; a cam attached to the shaft to fit a different-shaped portion of the shaft to prevent rotation of the cam in a circumferential direction of the shaft, the different-shaped portion having a different shape in cross section from a round portion of the shaft; a lever having an inner hollow cylindrical portion larger than an outline of the shaft and attached to the shaft to be rotatable in the circumferential direction of the shaft; a spring attached to the shaft to press the cam and the lever in an axial direction of the shaft; and a retainer attached to the shaft to retain the spring, the cam, and the lever to the shaft. The cam has at least two valley portions. The lever has a contact portion to contact the cam. The contact portion has a base shape.

    GPR119 agonist
    7.
    发明授权
    GPR119 agonist 失效
    GPR119激动剂

    公开(公告)号:US08536176B2

    公开(公告)日:2013-09-17

    申请号:US13056673

    申请日:2009-07-31

    IPC分类号: A61K31/50 A61K31/501

    摘要: A cyclic amine derivative represented by the formula (II) is a GPR119 agonist, and is used as an agent for treating diabetes. wherein Ar0 is phenyl or phenyl having a substituent such as C1-8 alkylsulfonyl or the like, pyridyl, or pyridyl having a substituent such as C1-8 alkylsulfonyl; A0 is (CH2)p, O, or the like; B0 is (CH2)q, or the like, provided that B0 is neither O nor NR25 when A0 is O or NR24; one of U0 and V0 is N, and the other is N or CR26; each of X0 and Y0 is C1-3 alkylene or C1-3 alkylene having a substituent; R23 is a C1-8 alkyl group or the like; each of R21 and R22 is hydrogen, a halogen atom, or the like.

    摘要翻译: 由式(II)表示的环胺衍生物是GPR119激动剂,用作治疗糖尿病的药剂。 其中Ar 0是苯基或具有取代基的苯基,例如C1-8烷基磺酰基等,吡啶基或具有取代基的吡啶基,例如C1-8烷基磺酰基; A 0为(CH 2)p,O等; B0为(CH2)q等,条件是当A0为O或NR24时,B0既不为O也不为NR25; U0和V0之一是N,另一个是N或CR26; X0和Y0各自为C1-3亚烷基或具有取代基的C1-3亚烷基; R 23是C 1-8烷基等; R 21和R 22各自为氢,卤素原子等。

    Vinblastine synthesis
    9.
    发明授权
    Vinblastine synthesis 失效
    长春碱合成

    公开(公告)号:US5034320A

    公开(公告)日:1991-07-23

    申请号:US32459

    申请日:1987-03-31

    申请人: Tsuyoshi Endo

    发明人: Tsuyoshi Endo

    IPC分类号: C12N9/02 C12P17/18

    CPC分类号: C12P17/182

    摘要: The reaction of 3',4'-anhydrovinblastine with a Catharanthus roseus-derived protein fraction to form vinblastine is improved by conducting the reaction in the presence of a reducing agent such as the enzyme cofactor NADH. A cationic species such as manganous ion may also be added to the reaction. Vinblastine yields are enhanced.

    摘要翻译: 通过在还原剂如酶辅因子NADH的存在下进行反应来改善3',4'-脱氢长春花碱与长春花长春花衍生的蛋白质级分以形成长春花碱的反应。 还可以向反应中加入阳离子种类如二价锰离子。 长春花碱产量提高。