-
公开(公告)号：US08173155B2
公开(公告)日：2012-05-08
申请号：US11141727
申请日：2005-05-31
IPC分类号： A61F13/02
CPC分类号： A61K9/7053 , A61K9/7061 , A61K9/7069 , A61K9/7076
摘要： The present invention relates an adhesive patch comprising a backing layer and an adhesive layer that contains a drug, wherein the adhesive layer contains a mixed adhesive base containing a hydrocarbon rubber and a silicon-containing polymer. The adhesive patch of the invention shows extremely superior skin absorbability of a drug in a preparation, reduced skin irritation, and excellent aging stability of the drug in the preparation, and can achieve easiness of drug-taking methods and improvement in compliance.
摘要翻译： 本发明涉及包含背衬层和含有药物的粘合剂层的粘合贴剂，其中粘合剂层含有含有烃橡胶和含硅聚合物的混合粘合剂基料。 本发明的贴剂在制剂中显示出极好的药物在皮肤吸收性，皮肤刺激性降低，以及药物优良的老化稳定性，并且可以实现药物吸收方法的容易性和依从性的提高。
-
2.发明申请Process for production of pressure-sensitive adhesive moldings comprising crosslinked polymers as the main component 审中-公开用于生产包含交联聚合物作为主要成分的压敏粘合剂模制品的方法公开(公告)号：US20050119385A1
公开(公告)日：2005-06-02
申请号：US10502412
申请日：2003-01-24
CPC分类号： C09J133/04 , A61K9/7061 , A61K47/12 , A61L15/24 , A61L15/58 , C08J5/00 , C08L2312/00 , C08L33/08
摘要： The invention provides a process for production of pressure-sensitive adhesive shaped products which enables proper shaping of a tacky polymer through proper control of the rate of crosslinking thereof, specifically, a process for production of pressure-sensitive adhesive shaped products which comprises mixing a polymer bearing hydroxyl or carboxyl groups with one or more crosslinking agents selected from the group consisting of metal alcoholates and boron compounds in the presence of a lower alcohol and then subjecting the obtained mixture to shaping either accompanied with or followed by thermal crosslinking.
摘要翻译： 本发明提供了一种用于生产压敏粘合剂成型产品的方法，其通过适当地控制其交联速率，特别是生产压敏粘合剂成型产品的方法，使粘性聚合物能够适当地成形，该方法包括将聚合物 在低级醇的存在下，使用一种或多种选自金属醇化物和硼化合物的交联剂负载羟基或羧基，然后使所得混合物在伴随或随后进行热交联的条件下进行成型。
-
公开(公告)号：US20060193900A1
公开(公告)日：2006-08-31
申请号：US11362168
申请日：2006-02-27
CPC分类号： C09J133/08 , C08L33/08 , C08L39/06 , C08L2666/04 , C09J139/06 , C09J2201/606
摘要： The present invention is a pressure sensitive adhesive comprising: an ingredient (A) which is a copolymer of a carboxyl group-containing monomer and (meth)acrylic ester; and an ingredient (B) which is a copolymer of a pyrrolidone group-containing monomer and (meth)acrylic ester, wherein the ingredient (A) is crosslinked by at least one crosslinking agent selected from the group consisting of a metal chelate compound, a metal oxide and a metal hydroxide, and the blending ratio of the ingredient (A) is 70 to 90 weight % based on the total amount of the ingredient (A) and ingredient (B).
摘要翻译： 本发明是一种压敏粘合剂，包括：成分（A），其是含羧基的单体和（甲基）丙烯酸酯的共聚物; 和作为含有吡咯烷酮基的单体与（甲基）丙烯酸酯的共聚物的成分（B），其中成分（A）通过至少一种交联剂交联，所述交联剂选自金属螯合物， 金属氧化物和金属氢氧化物，并且成分（A）的配合比例相对于成分（A）和成分（B）的总量为70〜90重量％。
-
公开(公告)号：US20050053646A1
公开(公告)日：2005-03-10
申请号：US10502474
申请日：2003-01-24
CPC分类号： A61K9/7061
摘要： An adhesive which comprises aqueous and nonaqueous polymers suitable for holding an lipophilic drug, etc., and has tackiness and cohesiveness which are sufficient for the plaster of a patch; and a patch employing the adhesive. The adhesive contains a polymer which comprises one or more kinds of acrylic or methacrylic monomer units, at least one kind of the monomer units having a hydroxy group, and which has been crosslinked with a boron compound.
摘要翻译： 一种粘合剂，其包含适于保持亲脂性药物的水性和非水性聚合物等，并且具有足够的贴剂粘贴性和粘性; 和使用粘合剂的贴剂。 粘合剂含有包含一种或多种丙烯酸或甲基丙烯酸单体单元，至少一种具有羟基的单体单元并且已经与硼化合物交联的聚合物。
-
5.发明申请Pressure-Sensitive Adhesive Base and Medical Adhesive Patch Including the Pressure-Sensitive Adhesive Base 审中-公开压敏粘合剂基体和包括压敏粘合剂基底的医用胶粘剂公开(公告)号：US20090274747A1
公开(公告)日：2009-11-05
申请号：US11816869
申请日：2006-02-27
IPC分类号： A61K9/70
CPC分类号： A61K9/7061
摘要： A pressure-sensitive adhesive base which contains the liquid organic ingredient and which, despite this, has moderate pressure-sensitive adhesion properties (tackiness and cohesive force) and causes no bleeding. It hardly injures the keratin of the skin and is inhibited from irritating the skin. The pressure-sensitive adhesive base comprises the following ingredients (A) to (C): (A) a copolymer comprising units of a monomer containing a carboxy group and units of a (meth) acrylic ester; (B) one or more, liquid or semisolid organic compounds which are compatible with the copolymer of the ingredient (A); and (C) at least one member selected among polyvalent-metal oxides and polyvalent-metal hydroxides, the total content of the ingredient (C) being 0.001-5 mass % based on the whole pressure-sensitive adhesive base. The adhesive base contains substantially no water.
摘要翻译： 含有液体有机成分的压敏粘合剂基质，尽管如此，它具有适度的压敏粘合性（粘性和内聚力），并且不引起渗色。 它几乎不会伤害皮肤的角质，并且可以抑制皮肤刺激。 压敏粘合剂基底包含以下成分（A）〜（C）：（A）包含含有羧基的单体和（甲基）丙烯酸酯单元的单元的共聚物; （B）与成分（A）的共聚物相容的一种或多种液体或半固体有机化合物; 和（C）选自多价金属氧化物和多价金属氢氧化物中的至少一种，成分（C）的总含量相对于整个压敏粘合剂基质为0.001-5质量％。 胶粘剂基本上不含水。
-
公开(公告)号：US07034083B2
公开(公告)日：2006-04-25
申请号：US10502474
申请日：2003-01-24
IPC分类号： C08F8/00
CPC分类号： A61K9/7061
摘要： An adhesive which comprises aqueous and nonaqueous polymers suitable for holding an lipophilic drug, etc., and has tackiness and cohesiveness which are sufficient for the plaster of a patch; and a patch employing the adhesive. The adhesive contains a polymer which comprises one or more kinds of acrylic or methacrylic monomer units, at least one kind of the monomer units having a hydroxy group, and which has been crosslinked with a boron compound.
摘要翻译： 一种粘合剂，其包含适于保持亲脂性药物的水性和非水性聚合物等，并且具有足够的贴剂粘贴性和粘性; 和使用粘合剂的贴剂。 粘合剂含有包含一种或多种丙烯酸或甲基丙烯酸单体单元，至少一种具有羟基的单体单元并且已经与硼化合物交联的聚合物。
-
公开(公告)号：US4482416A
公开(公告)日：1984-11-13
申请号：US410834
申请日：1982-08-23
IPC分类号： B29D30/00 , B29C67/00 , B29D30/24 , B29D30/32 , B29D30/34 , B29D30/42 , B29D30/70 , B29H17/00
CPC分类号： B29D30/243 , B29D30/32 , B29D2030/3228 , B29D2030/3235 , Y10T156/101 , Y10T156/1015 , Y10T156/1033 , Y10T156/1038 , Y10T156/1044 , Y10T156/1049
摘要： For folding an annular resilient band about a circumferential fold line, the band is first wrapped on a generally cylindrical, radially collapsible drum structure having a cylindrical external contour about the center axis of the drum and an annular zone radially inward of the contour with an inflatable annular first bladder positioned in such a manner as to have a folded-over axial end portion axially protruding into the aforesaid annular zone and with an inflatable annular second bladder positioned radially inwardly of the first bladder and in such a manner that the first and second bladders have axial portions overlapping each other, whereupon the first bladder is inflated to a medium expanded state so that an axial end portion of the band on the drum structure is contacted by the bladder and displaced radially outwardly and thereafter the first bladder is moved axially away from the drum structure for forming an annular gap between the first bladder and the axial end portion of the band, the second bladder being thereafter inflated to a fully expanded state for deforming the first bladder axially between the band and the second bladder so that the axial end portion of the band is caused to further turn about the aforesaid fold line until the axial end portion of the band is received on an adjacent axial portion of the band.
摘要翻译： 为了围绕圆周折叠线折叠环形弹性带，该带首先被缠绕在大致圆柱形的径向可折叠的滚筒结构上，该滚筒结构具有围绕滚筒的中心轴线的圆柱形外部轮廓和具有可膨胀的轮廓的径向向内的环形区域 环形第一囊被定位成使得折叠的轴向端部轴向地突出到上述环形区域中，并且具有位于第一囊的径向内侧的可膨胀的环形第二囊，并且使得第一和第二囊 具有轴向部分彼此重叠，于是第一气囊膨胀至中等膨胀状态，使得鼓结构上的带的轴向端部与气囊接触并径向向外移动，此后第一气囊轴向移动 用于在第一气囊和轴向端部之间形成环形间隙的鼓结构 之后，第二囊被充气到完全膨胀状态，以使第一囊在带和第二囊之间轴向变形，使得带的轴向端部进一步转动围绕上述折叠线直到轴向端部 带被接收在带的相邻轴向部分上。
-
公开(公告)号：US20110008398A1
公开(公告)日：2011-01-13
申请号：US12919723
申请日：2009-02-09
CPC分类号： A61K31/4985 , A61K9/7061
摘要： Provided is a medicated patch containing a medicinal agent and an adhesive base material and having an acid value of no greater than 28, where the medicinal agent is varenicline or a pharmaceutically acceptable salt of varenicline.
摘要翻译： 本发明提供含有药剂和粘合剂基材并且酸值不大于28的药膏，其中药剂为伐伦克林或伐尼克兰的药学上可接受的盐。
-
公开(公告)号：US20050266063A1
公开(公告)日：2005-12-01
申请号：US11141727
申请日：2005-05-31
IPC分类号： A61K9/70
CPC分类号： A61K9/7053 , A61K9/7061 , A61K9/7069 , A61K9/7076
摘要： The present invention relates an adhesive patch comprising a backing layer and an adhesive layer that contains a drug, wherein the adhesive layer contains a mixed adhesive base containing a hydrocarbon rubber and a silicon-containing polymer. The adhesive patch of the invention shows extremely superior skin absorbability of a drug in a preparation, reduced skin irritation, and excellent aging stability of the drug in the preparation, and can achieve easiness of drug-taking methods and improvement in compliance.
摘要翻译： 本发明涉及包含背衬层和含有药物的粘合剂层的粘合贴剂，其中粘合剂层含有含有烃橡胶和含硅聚合物的混合粘合剂基料。 本发明的贴剂在制剂中显示出极好的药物在皮肤吸收性，皮肤刺激性降低，以及药物优良的老化稳定性，并且可以实现药物吸收方法的容易性和依从性的提高。
-
公开(公告)号：USRE45936E1
公开(公告)日：2016-03-22
申请号：US12108934
申请日：2008-04-24
CPC分类号： A61K9/7061 , A61K9/7069
摘要： An adhesive which comprises aqueous and nonaqueous polymers suitable for holding an lipophilic drug, etc., and has tackiness and cohesiveness which are sufficient for the plaster of a patch; and a patch employing the adhesive. The adhesive contains a polymer which comprises one or more kinds of acrylic or methacrylic monomer units, at least one kind of the monomer units having a hydroxy group, and which has been crosslinked with a boron compound.
-
-
-
-
-
-
-
-
-
搜索结果
12 条记录 (耗时 0.012 秒)
