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公开(公告)号：US08741884B2
公开(公告)日：2014-06-03
申请号：US13086704
申请日：2011-04-14
申请人： Tao Wang , Zhiwei Yin , Zhongxing Zhang , Annapurna Pendri , Guo Li , Samuel Gerritz , Weixu Zhai , Paul Michael Scola , Li-Qiang Sun , Eric Mull
发明人： Tao Wang , Zhiwei Yin , Zhongxing Zhang , Annapurna Pendri , Guo Li , Samuel Gerritz , Weixu Zhai , Paul Michael Scola , Li-Qiang Sun , Eric Mull
IPC分类号： A61K31/33 , C07D487/00
CPC分类号： C07D498/06
摘要： The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
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公开(公告)号：US20120093767A1
公开(公告)日：2012-04-19
申请号：US13086704
申请日：2011-04-14
申请人： Tao Wang , Zhiwei Yin , Zhongxing Zhang , Annapurna Pendri , Guo Li , Samuel Gerritz , Weixu Zhai , Paul Michael Scola , Li-Qiang Sun , Eric Mull
发明人： Tao Wang , Zhiwei Yin , Zhongxing Zhang , Annapurna Pendri , Guo Li , Samuel Gerritz , Weixu Zhai , Paul Michael Scola , Li-Qiang Sun , Eric Mull
IPC分类号： A61K38/20 , C07D487/08 , A61P31/14 , A61K38/21 , A61K38/13 , C07D498/08 , A61K31/53
CPC分类号： C07D498/06
摘要： The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
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公开(公告)号：US08445490B2
公开(公告)日：2013-05-21
申请号：US13086036
申请日：2011-04-13
申请人： Tao Wang , Annapurna Pendri , Zhongxing Zhang , Weixu Zhai , Guo Li , Samuel Gerritz , Paul Michael Scola , Li-Qiang Sun , Qian Zhao , Eric Mull
发明人： Tao Wang , Annapurna Pendri , Zhongxing Zhang , Weixu Zhai , Guo Li , Samuel Gerritz , Paul Michael Scola , Li-Qiang Sun , Qian Zhao , Eric Mull
IPC分类号： A61K31/53 , C07D251/18
CPC分类号： C07D487/08 , C07D498/08
摘要： The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
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公开(公告)号：US08586584B2
公开(公告)日：2013-11-19
申请号：US12904264
申请日：2010-10-14
申请人： Tao Wang , Annapurna Pendri , Zhongxing Zhang , Weixu Zhai , Guo Li , Samuel Gerritz , Paul Michael Scola , Li-Qiang Sun , Qian Zhao , Eric Mull
发明人： Tao Wang , Annapurna Pendri , Zhongxing Zhang , Weixu Zhai , Guo Li , Samuel Gerritz , Paul Michael Scola , Li-Qiang Sun , Qian Zhao , Eric Mull
IPC分类号： A61K31/53 , C07D251/72 , C07D487/00
CPC分类号： C07D487/08 , C07D498/08
摘要： The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
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公开(公告)号：US20120093766A1
公开(公告)日：2012-04-19
申请号：US13086036
申请日：2011-04-13
申请人： Tao Wang , Annapurna Pendri , Zhongxing Zhang , Weixu Zhai , Guo Li , Samuel Gerritz , Paul Michael Scola , Li-Qiang Sun , Qian Zhao , Eric Mull
发明人： Tao Wang , Annapurna Pendri , Zhongxing Zhang , Weixu Zhai , Guo Li , Samuel Gerritz , Paul Michael Scola , Li-Qiang Sun , Qian Zhao , Eric Mull
IPC分类号： A61K31/53 , C07D498/08 , A61K38/13 , A61K38/20 , A61P31/14 , C07D487/08 , A61K38/21
CPC分类号： C07D487/08 , C07D498/08
摘要： The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
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公开(公告)号：US20110086858A1
公开(公告)日：2011-04-14
申请号：US12904264
申请日：2010-10-14
申请人： Tao Wang , Annapurna Pendri , Zhongxing Zhang , Weixu Zhai , Guo Li , Samuel Gerritz , Paul Michael Scola , Li-Qiang Sun , Qian Zhao , Eric Mull
发明人： Tao Wang , Annapurna Pendri , Zhongxing Zhang , Weixu Zhai , Guo Li , Samuel Gerritz , Paul Michael Scola , Li-Qiang Sun , Qian Zhao , Eric Mull
IPC分类号： A61K31/53 , C07D245/00 , C07D267/00 , A61P31/14
CPC分类号： C07D487/08 , C07D498/08
摘要： The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
摘要翻译： 本公开提供式I化合物，包括药学上可接受的盐，以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒（HCV）的活性，可用于治疗HCV感染者。
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公开(公告)号：US08765944B2
公开(公告)日：2014-07-01
申请号：US13210776
申请日：2011-08-16
申请人： Li-Qiang Sun , Eric Mull , Qian Zhao , Tao Wang , Zhongxing Zhang , Paul Michael Scola
发明人： Li-Qiang Sun , Eric Mull , Qian Zhao , Tao Wang , Zhongxing Zhang , Paul Michael Scola
IPC分类号： C07D251/52 , A61K31/53 , A61P31/12
CPC分类号： C07D251/52 , A61K31/53 , A61K45/06 , C07D401/04 , C07D401/12 , C07D403/12 , A61K2300/00
摘要： The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
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公开(公告)号：US20120213729A1
公开(公告)日：2012-08-23
申请号：US13210776
申请日：2011-08-16
申请人： Li-Qiang Sun , Eric Mull , Qian Zhao , Tao Wang , Zhongxing Zhang , Paul Michael Scola
发明人： Li-Qiang Sun , Eric Mull , Qian Zhao , Tao Wang , Zhongxing Zhang , Paul Michael Scola
IPC分类号： A61K31/53 , A61K38/21 , A61K38/13 , A61K31/541 , A61K31/5377 , C07D403/04 , C07D413/12 , C07D251/52 , C07D403/12 , C07D401/14 , C07D401/12 , A61P31/14 , A61K38/20 , C07D417/12
CPC分类号： C07D251/52 , A61K31/53 , A61K45/06 , C07D401/04 , C07D401/12 , C07D403/12 , A61K2300/00
摘要： The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
摘要翻译： 本公开提供式I化合物，包括药学上可接受的盐，以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒（HCV）的活性，可用于治疗HCV感染者。
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公开(公告)号：US08957203B2
公开(公告)日：2015-02-17
申请号：US13459403
申请日：2012-04-30
申请人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
发明人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
IPC分类号： C07D225/00 , C07D295/00 , C07D245/00 , C07D225/04 , C07D487/00 , C07D487/04 , C07K5/083 , C07K5/08 , A61K38/20 , A61K38/21 , A61K45/06 , A61K31/13 , A61K31/4745 , A61K31/7056 , A61K38/00
CPC分类号： C07K5/0823 , A61K31/13 , A61K31/4745 , A61K31/7056 , A61K38/00 , A61K38/06 , A61K38/2013 , A61K38/204 , A61K38/2053 , A61K38/21 , A61K38/212 , A61K45/06 , C07D487/04 , C07K5/0804 , C07K5/0827 , A61K2300/00
摘要： Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
摘要翻译： 公开了具有通式（I）的丙型肝炎病毒抑制剂。 还公开了包含化合物的组合物和使用该化合物抑制HCV的方法。
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公开(公告)号：US20130115190A1
公开(公告)日：2013-05-09
申请号：US13459403
申请日：2012-04-30
申请人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
发明人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
CPC分类号： C07K5/0823 , A61K31/13 , A61K31/4745 , A61K31/7056 , A61K38/00 , A61K38/06 , A61K38/2013 , A61K38/204 , A61K38/2053 , A61K38/21 , A61K38/212 , A61K45/06 , C07D487/04 , C07K5/0804 , C07K5/0827 , A61K2300/00
摘要： Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
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