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公开(公告)号:US11407168B2
公开(公告)日:2022-08-09
申请号:US16437704
申请日:2019-06-11
申请人: Tepha, Inc.
发明人: Skander Limem , Reshad Bin Harun , Matthew Dubois , David P. Martin , Said Rizk
IPC分类号: B29C64/118 , B29C64/321 , B29C64/153 , B29C64/295 , B29C64/209 , B29C64/393 , B29C64/227 , B29C64/268 , A61L27/14 , A61L29/06 , B33Y10/00 , B33Y30/00 , B33Y50/02 , B33Y70/00 , B29K67/00
摘要: Methods to fabricate objects by 3D printing of poly-4-hydroxybutyrate (P4HB) and copolymers thereof have been developed. In one method, these objects are produced by continuous fused filament fabrication using an apparatus and conditions that overcome the problems of poor feeding of the filament resulting from the low softening temperature of the filament and heat creep along the fed filament. Methods using an apparatus including a heat sink, a melt tube, a heating block and nozzle, and a transition zone between the heat sink and heating block, with the melt tube extending through the heat sink, transition zone, and heat block to the nozzle are disclosed. 3D objects are also printed by fused pellet deposition (FPD), melt extrusion deposition (MED), selective laser melting (SLM), printing of slurries and solutions using a coagulation bath, and printing using a binding solution and polymer granules.
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公开(公告)号:US20240149523A1
公开(公告)日:2024-05-09
申请号:US18414218
申请日:2024-01-16
申请人: Tepha, Inc.
发明人: Skander Limem , Reshad Bin Harun , Matthew Dubois , David P. Martin , Said Rizk
IPC分类号: B29C64/118 , A61L27/14 , A61L29/06 , B29C64/153 , B29C64/209 , B29C64/227 , B29C64/268 , B29C64/295 , B29C64/321 , B29C64/393 , B33Y70/00 , B33Y70/10
CPC分类号: B29C64/118 , A61L27/14 , A61L29/06 , B29C64/153 , B29C64/209 , B29C64/227 , B29C64/268 , B29C64/295 , B29C64/321 , B29C64/393 , B33Y70/00 , B33Y70/10 , B33Y10/00
摘要: Methods to fabricate objects by 3D printing of poly-4-hydroxybutyrate (P4HB) and copolymers thereof have been developed. In one method, these objects are produced by continuous fused filament fabrication using an apparatus and conditions that overcome the problems of poor feeding of the filament resulting from the low softening temperature of the filament and heat creep along the fed filament. Methods using an apparatus including a heat sink, a melt tube, a heating block and nozzle, and a transition zone between the heat sink and heating block, with the melt tube extending through the heat sink, transition zone, and heat block to the nozzle are disclosed. 3D objects are also printed by fused pellet deposition (FPD), melt extrusion deposition (MED), selective laser melting (SLM), printing of slurries and solutions using a coagulation bath, and printing using a binding solution and polymer granules.
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公开(公告)号:US11904529B2
公开(公告)日:2024-02-20
申请号:US18187452
申请日:2023-03-21
申请人: Tepha, Inc.
发明人: Skander Limem , Reshad Bin Harun , Matthew Dubois , David P. Martin , Said Rizk
IPC分类号: B33Y70/00 , B29C64/118 , B29C64/321 , B29C64/153 , B29C64/295 , B29C64/209 , B29C64/393 , B29C64/227 , B29C64/268 , A61L27/14 , A61L29/06 , B33Y70/10 , B33Y10/00 , B33Y30/00 , B33Y50/02 , B29K67/00
CPC分类号: B29C64/118 , A61L27/14 , A61L29/06 , B29C64/153 , B29C64/209 , B29C64/227 , B29C64/268 , B29C64/295 , B29C64/321 , B29C64/393 , B33Y70/00 , B33Y70/10 , B29K2067/04 , B33Y10/00 , B33Y30/00 , B33Y50/02
摘要: Methods to fabricate objects by 3D printing of poly-4-hydroxybutyrate (P4HB) and copolymers thereof have been developed. In one method, these objects are produced by continuous fused filament fabrication using an apparatus and conditions that overcome the problems of poor feeding of the filament resulting from the low softening temperature of the filament and heat creep along the fed filament. Methods using an apparatus including a heat sink, a melt tube, a heating block and nozzle, and a transition zone between the heat sink and heating block, with the melt tube extending through the heat sink, transition zone, and heat block to the nozzle are disclosed. 3D objects are also printed by fused pellet deposition (FPD), melt extrusion deposition (MED), selective laser melting (SLM), printing of slurries and solutions using a coagulation bath, and printing using a binding solution and polymer granules.
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公开(公告)号:US20230165673A1
公开(公告)日:2023-06-01
申请号:US18075202
申请日:2022-12-05
申请人: Tepha, Inc.
发明人: Skander Limem , Bhavin Shah , Said Rizk , Matthew Dubois , Simon F. Williams
CPC分类号: A61F2/12 , A61F2/0063 , A61K35/35 , A61L27/54 , A61B90/02 , A61B2017/00969
摘要: Expandable absorbable implants have been developed that are suitable for breast reconstruction following mastectomy. The implants can be implanted in the vicinity of a tissue expander, for example, by suturing to the detached edge of the pectoralis major muscle to function as a pectoralis extender, and used to form a sling for a tissue expander. The implants, which permit tissue-ingrowth and slowly degrade, can be expanded in the breast using a tissue expander in order to form a pocket for a permanent breast implant. After expansion, the tissue expander can be removed and replaced with a permanent breast implant. The expandable implants help reduce patient discomfort resulting from tissue expansion, and avoid the need to use allografts or xenografts to create the pocket for the tissue expander. The expandable absorbable implant preferably comprises poly-4-hydroxybutyrate or copolymer thereof.
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公开(公告)号:US20230226749A1
公开(公告)日:2023-07-20
申请号:US18187452
申请日:2023-03-21
申请人: Tepha, Inc.
发明人: Skander Limem , Reshad Bin Harun , Matthew Dubois , David P. Martin , Said Rizk
IPC分类号: B29C64/118 , B29C64/295 , B29C64/268 , A61L29/06 , B29C64/209 , B29C64/153 , A61L27/14 , B33Y70/10 , B29C64/321 , B33Y70/00 , B29C64/393 , B29C64/227 , B33Y10/00 , B33Y30/00 , B33Y50/02 , B29K67/00
CPC分类号: B29C64/118 , B29C64/295 , B29C64/268 , A61L29/06 , B29C64/209 , B29C64/153 , A61L27/14 , B33Y70/10 , B29C64/321 , B33Y70/00 , B29C64/393 , B29C64/227 , B33Y10/00 , B33Y30/00 , B33Y50/02 , B29K2067/04
摘要: Methods to fabricate objects by 3D printing of poly-4-hydroxybutyrate (P4HB) and copolymers thereof have been developed. In one method, these objects are produced by continuous fused filament fabrication using an apparatus and conditions that overcome the problems of poor feeding of the filament resulting from the low softening temperature of the filament and heat creep along the fed filament. Methods using an apparatus including a heat sink, a melt tube, a heating block and nozzle, and a transition zone between the heat sink and heating block, with the melt tube extending through the heat sink, transition zone, and heat block to the nozzle are disclosed. 3D objects are also printed by fused pellet deposition (FPD), melt extrusion deposition (MED), selective laser melting (SLM), printing of slurries and solutions using a coagulation bath, and printing using a binding solution and polymer granules.
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公开(公告)号:US11554007B2
公开(公告)日:2023-01-17
申请号:US16279378
申请日:2019-02-19
申请人: Tepha, Inc.
发明人: Skander Limem , Bhavin Shah , Said Rizk , Matthew Dubois , Simon F. Williams
摘要: Expandable absorbable implants have been developed that are suitable for breast reconstruction following mastectomy. The implants can be implanted in the vicinity of a tissue expander, for example, by suturing to the detached edge of the pectoralis major muscle to function as a pectoralis extender, and used to form a sling for a tissue expander. The implants, which permit tissue-ingrowth and slowly degrade, can be expanded in the breast using a tissue expander in order to form a pocket for a permanent breast implant. After expansion, the tissue expander can be removed and replaced with a permanent breast implant. The expandable implants help reduce patient discomfort resulting from tissue expansion, and avoid the need to use allografts or xenografts to create the pocket for the tissue expander. The expandable absorbable implant preferably comprises poly-4-hydroxybutyrate or copolymer thereof.
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公开(公告)号:US11639024B2
公开(公告)日:2023-05-02
申请号:US17852127
申请日:2022-06-28
申请人: Tepha, Inc.
发明人: Skander Limem , Reshad Bin Harun , Matthew Dubois , David P. Martin , Said Rizk
IPC分类号: B29C64/118 , B33Y70/00 , B29C64/321 , B29C64/153 , B29C64/295 , B29C64/209 , B29C64/393 , B29C64/227 , B29C64/268 , A61L27/14 , A61L29/06 , B33Y70/10 , B33Y10/00 , B33Y30/00 , B33Y50/02 , B29K67/00
摘要: Methods to fabricate objects by 3D printing of poly-4-hydroxybutyrate (P4HB) and copolymers thereof have been developed. In one method, these objects are produced by continuous fused filament fabrication using an apparatus and conditions that overcome the problems of poor feeding of the filament resulting from the low softening temperature of the filament and heat creep along the fed filament. Methods using an apparatus including a heat sink, a melt tube, a heating block and nozzle, and a transition zone between the heat sink and heating block, with the melt tube extending through the heat sink, transition zone, and heat block to the nozzle are disclosed. 3D objects are also printed by fused pellet deposition (FPD), melt extrusion deposition (MED), selective laser melting (SLM), printing of slurries and solutions using a coagulation bath, and printing using a binding solution and polymer granules.
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公开(公告)号:US20220324162A1
公开(公告)日:2022-10-13
申请号:US17852127
申请日:2022-06-28
申请人: Tepha, Inc.
发明人: Skander Limem , Reshad Bin Harun , Matthew Dubois , David P. Martin , Said Rizk
IPC分类号: B29C64/118 , B29C64/321 , B29C64/153 , B29C64/295 , B29C64/209 , B29C64/393 , B29C64/227 , B29C64/268 , A61L27/14 , A61L29/06
摘要: Methods to fabricate objects by 3D printing of poly-4-hydroxybutyrate (P4HB) and copolymers thereof have been developed. In one method, these objects are produced by continuous fused filament fabrication using an apparatus and conditions that overcome the problems of poor feeding of the filament resulting from the low softening temperature of the filament and heat creep along the fed filament. Methods using an apparatus including a heat sink, a melt tube, a heating block and nozzle, and a transition zone between the heat sink and heating block, with the melt tube extending through the heat sink, transition zone, and heat block to the nozzle are disclosed. 3D objects are also printed by fused pellet deposition (FPD), melt extrusion deposition (MED), selective laser melting (SLM), printing of slurries and solutions using a coagulation bath, and printing using a binding solution and polymer granules.
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公开(公告)号:US20190254807A1
公开(公告)日:2019-08-22
申请号:US16279378
申请日:2019-02-19
申请人: Tepha, Inc.
发明人: Skander Limem , Bhavin Shah , Said Rizk , Matthew Dubois , Simon F. Williams
摘要: Expandable absorbable implants have been developed that are suitable for breast reconstruction following mastectomy. The implants can be implanted in the vicinity of a tissue expander, for example, by suturing to the detached edge of the pectoralis major muscle to function as a pectoralis extender, and used to form a sling for a tissue expander. The implants, which permit tissue-ingrowth and slowly degrade, can be expanded in the breast using a tissue expander in order to form a pocket for a permanent breast implant. After expansion, the tissue expander can be removed and replaced with a permanent breast implant. The expandable implants help reduce patient discomfort resulting from tissue expansion, and avoid the need to use allografts or xenografts to create the pocket for the tissue expander. The expandable absorbable implant preferably comprises poly-4-hydroxybutyrate or copolymer thereof.
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