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1.发明公开公开(公告)号：US20240252624A1
公开(公告)日：2024-08-01
申请号：US18000357
申请日：2021-06-16
发明人： Teshome Mebatsion , Aemro Kassa
IPC分类号： A61K39/295 , A61K39/00 , A61K39/12 , A61K39/145 , A61K39/17 , A61K39/255 , A61P31/14 , A61P31/16 , A61P31/22 , C07K14/005 , C12N15/86
CPC分类号： A61K39/295 , A61K39/12 , A61K39/145 , A61K39/17 , A61K39/255 , A61P31/14 , A61P31/16 , A61P31/22 , C07K14/005 , C12N15/86 , A61K2039/5256 , A61K2039/552 , A61K2039/70 , C12N2710/16334 , C12N2710/16343 , C12N2720/10022 , C12N2720/10034 , C12N2760/16122 , C12N2760/16134 , C12N2760/18122 , C12N2760/18134
摘要： Recombinant viral vectors and compositions that include them for use as vehicles to induce an immunological response. Multivalent viral vectors may be used in compositions or vaccines containing one or more recombinant viral vectors for protection against a variety of pathogens. Formation of these viral vectors may include insertion and expression of foreign genes to protect against a variety of pathogens. Further provided are methods of making and using the recombinant viral vectors, as well as immunogenic compositions that include the vectors and/or antigens. In particular, immunogenic compositions may include recombinant viral vectors such as vHVT509, vHVT522, and/or vHVT523.
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2.发明申请公开(公告)号：US20190249196A1
公开(公告)日：2019-08-15
申请号：US16393743
申请日：2019-04-24
发明人： Michel Bublot , Teshome Mebatsion , Joyce Pritchard , Perry Linz , Aemro Kassa
IPC分类号： C12N15/869 , A61K39/155 , A61K39/245 , A61K39/295 , C07K14/03 , C07K14/08 , C12N7/00 , A61K39/12
摘要： The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
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公开(公告)号：US11421249B2
公开(公告)日：2022-08-23
申请号：US17035109
申请日：2020-09-28
发明人： Michel Bublot , Teshome Mebatsion , Joyce Pritchard , Perry Linz , Aemro Kassa
IPC分类号： C12N15/869 , A61K39/12 , A61K39/155 , A61K39/245 , A61K39/295 , C07K14/03 , C07K14/08 , C12N7/00
摘要： The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
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公开(公告)号：US10323257B2
公开(公告)日：2019-06-18
申请号：US15840764
申请日：2017-12-13
发明人： Michel Bublot , Teshome Mebatsion , Joyce Pritchard , Perry Linz , Aemro Kassa
IPC分类号： C12N7/00 , A61K39/12 , C07K14/03 , C07K14/08 , A61K39/155 , A61K39/245 , A61K39/295 , C12N15/869
摘要： The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
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公开(公告)号：US20210010033A1
公开(公告)日：2021-01-14
申请号：US17035109
申请日：2020-09-28
发明人： Michel Bublot , Teshome Mebatsion , Joyce Pritchard , Perry Linz , Aemro Kassa
IPC分类号： C12N15/869 , A61K39/12 , A61K39/155 , A61K39/245 , A61K39/295 , C07K14/03 , C07K14/08 , C12N7/00
摘要： The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
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公开(公告)号：US10822620B2
公开(公告)日：2020-11-03
申请号：US16393743
申请日：2019-04-24
发明人： Michel Bublot , Teshome Mebatsion , Joyce Pritchard , Perry Linz , Aemro Kassa
IPC分类号： C12N15/869 , A61K39/12 , A61K39/155 , A61K39/245 , A61K39/295 , C07K14/03 , C07K14/08 , C12N7/00
摘要： The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
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7.发明授权公开(公告)号：US10751407B2
公开(公告)日：2020-08-25
申请号：US15961635
申请日：2018-04-24
发明人： Teshome Mebatsion , Aemro Kassa , Taejoong Kim
摘要： The present invention encompasses recombinant porcine reproductive and respiratory syndrome virus (PRRSV) vaccines or compositions. In particular, the invention encompasses recombinant adenovirus vectors encoding and expressing PRRSV gp2, gp3, gp4, gp5a, gp5 and/or E antigens, proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals from PRRSV.
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