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1.
公开(公告)号:US20190085324A1
公开(公告)日:2019-03-21
申请号:US15965192
申请日:2018-04-27
申请人: The Broad Institute Inc. , Massachusetts Institute of Technology , The Regents of the University of California
发明人: Aviv Regev , Brittany Adamson , Brian Cleary , Le Cong , Atray Dixit , Jellert Gaublomme , Eric S. Lander , Thomas Norman , Oren Parnas , Orit Rozenblatt-Rosen , Alexander K. Shalek , Jonathan Weissman
IPC分类号: C12N15/10 , C12N15/11 , C12N9/22 , C12N15/113 , C12Q1/6886
摘要: The present invention provides tools and methods for the systematic analysis of genetic interactions, including higher order interactions. The present invention provides tools and methods for combinatorial probing of cellular circuits, for dissecting cellular circuitry, for delineating molecular pathways, and/or for identifying relevant targets for therapeutics development.
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2.
公开(公告)号:US11214797B2
公开(公告)日:2022-01-04
申请号:US15965192
申请日:2018-04-27
申请人: The Broad Institute, Inc. , Massachusetts Institute of Technology , The Regents of the University of California
发明人: Aviv Regev , Brittany Adamson , Brian Cleary , Le Cong , Atray Dixit , Jellert Gaublomme , Eric S. Lander , Thomas Norman , Oren Parnas , Orit Rozenblatt-Rosen , Alexander K. Shalek , Jonathan Weissman
IPC分类号: C12N15/10 , G16B5/00 , C12N9/22 , C12N15/11 , C12N15/113 , C12Q1/6886
摘要: The present invention provides tools and methods for the systematic analysis of genetic interactions, including higher order interactions. The present invention provides tools and methods for combinatorial probing of cellular circuits, for dissecting cellular circuitry, for delineating molecular pathways, and/or for identifying relevant targets for therapeutics development.
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