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公开(公告)号：US10053694B2
公开(公告)日：2018-08-21
申请号：US15171883
申请日：2016-06-02
IPC分类号： C12N15/11 , C12N15/113 , C12Q1/6881 , C12Q1/6886 , A61K9/127 , A61K31/713 , C12Q1/6876
CPC分类号： C12N15/1137 , A61K9/1271 , A61K31/713 , C12N15/113 , C12N15/1135 , C12N15/1136 , C12N2310/113 , C12N2310/14 , C12N2310/141 , C12N2310/314 , C12N2310/315 , C12N2310/3181 , C12N2310/321 , C12N2310/3231 , C12N2310/3233 , C12N2310/346 , C12N2320/30 , C12N2320/32 , C12N2330/31 , C12Q1/6876 , C12Q1/6881 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , C12Q2600/178 , C12Y201/01043
摘要： This invention relates to long non-coding RNAs (lncRNAs), libraries of those ncRNAs that bind chromatin modifiers, such as Polycomb Repressive Complex 2, inhibitory nucleic acids and methods and compositions for targeting lncRNAs.
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公开(公告)号：US09816094B2
公开(公告)日：2017-11-14
申请号：US15171706
申请日：2016-06-02
IPC分类号： C12N15/11 , C12N15/113 , C12Q1/68 , A61K9/127 , A61K31/713
CPC分类号： C12N15/1137 , A61K9/1271 , A61K31/713 , C12N15/113 , C12N15/1135 , C12N15/1136 , C12N2310/113 , C12N2310/14 , C12N2310/141 , C12N2310/314 , C12N2310/315 , C12N2310/3181 , C12N2310/321 , C12N2310/3231 , C12N2310/3233 , C12N2310/346 , C12N2320/30 , C12N2320/32 , C12N2330/31 , C12Q1/6876 , C12Q1/6881 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , C12Q2600/178 , C12Y201/01043
摘要： This invention relates to long non-coding RNAs (lncRNAs), libraries of those ncRNAs that bind chromatin modifiers, such as Polycomb Repressive Complex 2, inhibitory nucleic acids and methods and compositions for targeting lncRNAs.
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公开(公告)号：US11066673B2
公开(公告)日：2021-07-20
申请号：US15265104
申请日：2016-09-14
IPC分类号： C12N15/11 , C12N15/113 , C12Q1/6881 , C12Q1/6886 , A61K9/127 , A61K31/713 , C12Q1/6876
摘要： This invention relates to long non-coding RNAs (lncRNAs), libraries of those lncRNAs that bind chromatin modifiers, such as Polycomb Repressive Complex 2, inhibitory nucleic acids and methods and compositions for targeting lncRNAs.
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公开(公告)号：US10119144B2
公开(公告)日：2018-11-06
申请号：US15050273
申请日：2016-02-22
IPC分类号： C12N15/11 , C12N15/113 , C12Q1/6881 , C12Q1/6886 , A61K9/127 , A61K31/713 , C12Q1/6876
摘要： This invention relates to long non-coding RNAs (lncRNAs), libraries of those ncRNAs that bind chromatin modifiers, such as Polycomb Repressive Complex 2, inhibitory nucleic acids and methods and compositions for targeting lncRNAs.
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公开(公告)号：US20170022504A1
公开(公告)日：2017-01-26
申请号：US15171860
申请日：2016-06-02
IPC分类号： C12N15/113 , A61K9/127 , A61K31/713
CPC分类号： C12N15/1137 , A61K9/1271 , A61K31/713 , C12N15/113 , C12N15/1135 , C12N15/1136 , C12N2310/113 , C12N2310/14 , C12N2310/141 , C12N2310/314 , C12N2310/315 , C12N2310/3181 , C12N2310/321 , C12N2310/3231 , C12N2310/3233 , C12N2310/346 , C12N2320/30 , C12N2320/32 , C12N2330/31 , C12Q1/6876 , C12Q1/6881 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , C12Q2600/178 , C12Y201/01043
摘要： This invention relates to long non-coding RNAs (lncRNAs), libraries of those ncRNAs that bind chromatin modifiers, such as Polycomb Repressive Complex 2, inhibitory nucleic acids and methods and compositions for targeting lncRNAs.
摘要翻译： 本发明涉及长非编码RNA（lncRNA），结合染色质修饰剂的那些ncRNA的文库，例如Polycomb Repressive Complex 2，抑制性核酸以及用于靶向lncRNA的方法和组合物。
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公开(公告)号：US09920317B2
公开(公告)日：2018-03-20
申请号：US13921738
申请日：2013-06-19
IPC分类号： C07H21/02 , C07H21/04 , C12N15/113
CPC分类号： C12N15/113 , C12N2310/11 , C12N2310/113 , C12N2310/3231
摘要： This invention relates to polycomb-associated long non-coding RNAs (lncRNAs), libraries and fragments of those ncRNAs, inhibitory nucleic acids and methods and compositions for targeting lncRNAs.
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公开(公告)号：US20170335317A1
公开(公告)日：2017-11-23
申请号：US15522171
申请日：2015-10-30
发明人： Jeannie T. Lee , Kavitha Sarma
CPC分类号： C12N15/1093 , A61K31/713 , A61K39/395 , C12N5/00 , C12N15/11 , C12N2310/113 , C12N2310/1241 , C12N2310/14 , C12N2310/15 , C12N2310/531 , C12N2320/11 , C12N2330/31 , C12P19/34 , C40B20/08 , C40B50/06 , G01N2333/914 , G01N2500/02
摘要： Methods and compositions for modulation of the activity of alpha thalassemia/mental retardation syndrome X-linked (ATRX), e.g., modulation of DNA-ATRX or RNA-ATRX interactions, and methods for identifying and using compounds that modulate DNA-ATRX or RNA-ATRX interactions, as well as the compounds themselves.
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公开(公告)号：US20170037396A1
公开(公告)日：2017-02-09
申请号：US13921738
申请日：2013-06-19
IPC分类号： C12N15/113
CPC分类号： C12N15/113 , C12N2310/11 , C12N2310/113 , C12N2310/3231
摘要： This invention relates to polycomb-associated long non-coding RNAs (lncRNAs), libraries and fragments of those ncRNAs, inhibitory nucleic acids and methods and compositions for targeting lncRNAs.
摘要翻译： 本发明涉及多梳相关长的非编码RNA（lncRNA），这些ncRNA的文库和片段，抑制性核酸和用于靶向lncRNA的方法和组合物。
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公开(公告)号：US20220119817A1
公开(公告)日：2022-04-21
申请号：US17350018
申请日：2021-06-17
IPC分类号： C12N15/113 , C12Q1/6881 , C12Q1/6886 , A61K9/127 , A61K31/713 , C12Q1/6876
摘要： This invention relates to long non-coding RNAs (lncRNAs), libraries of those lncRNAs that bind chromatin modifiers, such as Polycomb Repressive Complex 2, inhibitory nucleic acids and methods and compositions for targeting lncRNAs.
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公开(公告)号：US10358644B2
公开(公告)日：2019-07-23
申请号：US15821039
申请日：2017-11-22
IPC分类号： C07H21/02 , C07H21/04 , C12N15/113
摘要： This invention relates to polycomb-associated long non-coding RNAs (lncRNAs), libraries and fragments of those ncRNAs, inhibitory nucleic acids and methods and compositions for targeting lncRNAs.
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