公开(公告)号：US11913013B2

公开(公告)日：2024-02-27

申请号：US17389421

申请日：2021-07-30

申请人： The Government of the United States of America as Represented by the Secretary of the Department of Health and Human Services ,  Sabin Vaccine Institute

发明人： Nancy J. Sullivan ,  Gary J. Nabel ,  Clement Asiedu ,  Cheng Cheng ,  Alfredo Nicosia ,  Riccardo Cortese ,  Virginia Ammendola ,  Stefano Colloca

IPC分类号： C12N15/86 ,  C12N15/861 ,  C07K14/08 ,  A61K39/12 ,  C07K14/005 ,  A61K39/00 ,  C12N15/863 ,  C12N7/00

CPC分类号： C12N15/86 ,  A61K39/12 ,  C07K14/005 ,  C07K14/08 ,  C12N15/861 ,  A61K2039/5254 ,  A61K2039/5256 ,  A61K2039/545 ,  C12N7/00 ,  C12N15/8636 ,  C12N2710/10341 ,  C12N2710/10343 ,  C12N2710/24111 ,  C12N2710/24141 ,  C12N2760/14111 ,  C12N2760/14134

摘要： This invention provides vaccines for inducing an immune response and protection against filovirus infection for use as a preventative vaccine in humans. In particular, the invention provides chimpanzee adenoviral vectors expressing filovirus proteins from different strains of Ebolavirus (EBOV) or Marburg virus (MARV).

公开(公告)号：US10584355B2

公开(公告)日：2020-03-10

申请号：US15339225

申请日：2016-10-31

申请人： THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES ,  GLAXOSMITHKLINE BIOLOGICALS SA

发明人： Nancy J. Sullivan ,  Gary J Nabel ,  Clement Asiedu ,  Cheng Cheng ,  Alfredo Nicosia ,  Riccardo Cortese ,  Virginia Ammendola ,  Stefano Colloca

IPC分类号： C12N15/86 ,  A61K39/12 ,  C07K14/005 ,  C12N7/00 ,  A61K39/00

摘要： This invention provides vaccines for inducing an immune response and protection against filovirus infection for use as a preventative vaccine in humans. In particular, the invention provides chimpanzee adenoviral vectors expressing filovirus proteins from different strains of Ebolavirus (EBOV) or Marburg virus (MARV).

公开(公告)号：US20220064669A1

公开(公告)日：2022-03-03

申请号：US17389421

申请日：2021-07-30

申请人： The Gov. of the U.S.A as Represented by the Secretary of the Department of Health and Human Services ,  Sabin Vaccine Institute

发明人： Nancy J. Sullivan ,  Gary J. Nabel ,  Clement Asiedu ,  Cheng Cheng ,  Alfredo Nicosia ,  Riccardo Cortese ,  Virginia Ammendola ,  Stefano Colloca

IPC分类号： C12N15/86 ,  C12N15/861 ,  C07K14/005 ,  C12N7/00 ,  C12N15/863 ,  C07K14/08 ,  A61K39/12 ,  A61K39/00

摘要： This invention provides vaccines for inducing an immune response and protection against filovirus infection for use as a preventative vaccine in humans. In particular, the invention provides chimpanzee adenoviral vectors expressing filovirus proteins from different strains of Ebolavirus (EBOV) or Marburg virus (MARV).