公开(公告)号：US09103727B2

公开(公告)日：2015-08-11

申请号：US13729983

申请日：2012-12-28

Applicant: The Regents of the University of Michigan

Inventor： Xudong Fan ,  Karthik Reddy ,  Yunbo Guo

IPC: G01B9/02 ,  G01J3/45 ,  G01N21/27 ,  G01N21/39 ,  G01N30/74

CPC classification number: G01J3/45 ,  G01N21/274 ,  G01N21/39 ,  G01N30/74

Abstract: A self-referencing composite Fabry-Pérot cavity sensor, including methods of use and manufacture. The cavity sensor comprises a substrate defining a first cavity portion juxtaposed to a second cavity portion. The first and second cavity portions are provided having a predetermined depth offset. A polymer or other dielectric material is disposed within the first and second cavity portions. An interference spectrum resulting from a light source of a known wavelength is reflected through the sensor and produces a first refractive index from the first cavity portion offset by a second refractive index from the second cavity portion. The difference in refractive indices can be used to determine various physical parameters. An optical sensor according to the present technology may be used with vapor sensing, pressure sensing, protein detection, photo-acoustic imaging, and the like.

Abstract translation: 自参考复合法布里 - 珀罗腔传感器，包括使用和制造方法。 空腔传感器包括限定与第二空腔部分并置的第一空腔部分的基板。 第一和第二空腔部分具有预定的深度偏移。 聚合物或其它介电材料设置在第一和第二空腔部分内。 由已知波长的光源产生的干涉光谱通过传感器反射，并从第一空腔部分产生偏离第二空腔部分的第二折射率的第一折射率。 折射率的差异可用于确定各种物理参数。 根据本技术的光学传感器可以与蒸气感测，压力感测，蛋白质检测，光声成像等一起使用。

公开(公告)号：US10267763B2

公开(公告)日：2019-04-23

申请号：US15037809

申请日：2014-12-04

Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN

Inventor： Zhaohui Zhong ,  Girish Kulkarni ,  Karthik Reddy ,  Xudong Fan

IPC: B01D53/02 ,  B82Y30/00 ,  G01N27/414

Abstract: An improved sensing method is provided for rapid analyte detection. The method includes: applying an AC excitation signal to the channel region of the transistor; applying an AC drive signal to the transistor; delivering an analyte of interest to a channel region of a transistor; and monitoring a mixing current of the excitation signal and the drive signal through the transistor, where a change in the mixing current is indicative of the concentration of the analyte of interest.

公开(公告)号：US20130169970A1

公开(公告)日：2013-07-04

申请号：US13729983

申请日：2012-12-28

Applicant: The Regents of the University of Michigan

Inventor： Xudong Fan ,  Karthik Reddy ,  Yunbo Guo

IPC: G01J3/45

CPC classification number: G01J3/45 ,  G01N21/274 ,  G01N21/39 ,  G01N30/74

Abstract: A self-referencing composite Fabry-Pérot cavity sensor, including methods of use and manufacture. The cavity sensor comprises a substrate defining a first cavity portion juxtaposed to a second cavity portion. The first and second cavity portions are provided having a predetermined depth offset. A polymer or other dielectric material is disposed within the first and second cavity portions. An interference spectrum resulting from a light source of a known wavelength is reflected through the sensor and produces a first refractive index from the first cavity portion offset by a second refractive index from the second cavity portion. The difference in refractive indices can be used to determine various physical parameters. An optical sensor according to the present technology may be used with vapor sensing, pressure sensing, protein detection, photo-acoustic imaging, and the like.

Abstract translation: 自参考复合法布里 - 珀罗腔传感器，包括使用和制造方法。 空腔传感器包括限定与第二空腔部分并置的第一空腔部分的基板。 第一和第二空腔部分具有预定的深度偏移。 聚合物或其它介电材料设置在第一和第二空腔部分内。 由已知波长的光源产生的干涉光谱通过传感器反射，并从第一空腔部分产生偏离第二空腔部分的第二折射率的第一折射率。 折射率的差异可用于确定各种物理参数。 根据本技术的光学传感器可以与蒸气感测，压力感测，蛋白质检测，光声成像等一起使用。