公开(公告)号：US09778113B2

公开(公告)日：2017-10-03

申请号：US14253250

申请日：2014-04-15

申请人： The Trustees Of Columbia University In The City Of New York

发明人： Dirk R. Englund ,  Chaitanya Rastogi

IPC分类号： G01J3/45 ,  G01J3/26 ,  G01J3/32 ,  G01J3/02 ,  G01J3/28

CPC分类号： G01J3/45 ,  G01J3/0259 ,  G01J3/26 ,  G01J3/2823 ,  G01J3/32 ,  G01J2003/2826 ,  G01J2003/452

摘要： Techniques for hyperspectral imaging, including a device for hyperspectral imaging including at least one tunable interferometer including a thin layer of material disposed between two or more broadband mirrors. Electrodes placed on either side of the tunable interferometer can be coupled to a voltage control circuit, and upon application of a voltage across the tunable interferometer, the distance between the mirrors can be modulated by physically altering the dimensions of the thin layer of material, which can uniformly load the broadband mirrors. Physically altering the dimensions of the thin layer of material can include one or more of deformation of a soft material, piezostrictrive actuation of a piezostrictrive material, or electrostrictive actuation of an electrostrictive material.

公开(公告)号：US20140354999A1

公开(公告)日：2014-12-04

申请号：US14253250

申请日：2014-04-15

申请人： The Trustees of Columbia University In The City of New York

发明人： Dirk R. Englund ,  Chaitanya Rastogi

IPC分类号： G01J3/45 ,  G01J3/28

CPC分类号： G01J3/45 ,  G01J3/0259 ,  G01J3/26 ,  G01J3/2823 ,  G01J3/32 ,  G01J2003/2826 ,  G01J2003/452

摘要： Techniques for hyperspectral imaging, including a device for hyperspectral imaging including at least one tunable interferometer including a thin layer of material disposed between two or more broadband mirrors. Electrodes placed on either side of the tunable interferometer can be coupled to a voltage control circuit, and upon application of a voltage across the tunable interferometer, the distance between the mirrors can be modulated by physically altering the dimensions of the thin layer of material, which can uniformly load the broadband mirrors. Physically altering the dimensions of the thin layer of material can include one or more of deformation of a soft material, piezostrictrive actuation of a piezostrictrive material, or electrostrictive actuation of an electrostrictive material.

摘要翻译： 用于高光谱成像的技术，包括用于高光谱成像的装置，包括至少一个可调谐干涉仪，其包括设置在两个或更多个宽带镜之间的薄层材料。 放置在可调谐干涉仪两侧的电极可以耦合到电压控制电路，并且在可调谐干涉仪上施加电压时，反射镜之间的距离可以通过物理地改变薄层材料的尺寸来调节， 可以均匀地加载宽带镜。 物理上改变材料薄层的尺寸可以包括柔软材料的变形，压电致动材料的压电致动器致动或电致伸缩材料的电致伸缩致动中的一个或多个。

公开(公告)号：US20140100472A1

公开(公告)日：2014-04-10

申请号：US14104931

申请日：2013-12-12

申请人： The Trustees of Columbia University in the City of New York

发明人： Dirk R. Englund ,  Aurel A. Lazar ,  Chaitanya Rastogi ,  Yevgeniy B. Slutskiy

IPC分类号： A61B5/04 ,  A61B5/00

CPC分类号： A61B5/04001 ,  A61B5/7228 ,  G01N33/5058 ,  G01N33/54373 ,  G01N33/582

摘要： Systems for untethered sensing and recording of activity of one or more electrically excitable cells in a target region includes at least one untethered probe. Each untethered probe includes at least one signal detector, configured to electrically couple to the target region, measure the activity of the one or more electrically excitable cells, and produce an electrical signal in response to the activity of the one or more electrically excitable cells, and at least one light source, electrically coupled to the at least one signal detector, to receive the electrical signal and emit a light signal representing the activity of the one or more electrically excitable cells. Methods for untethered sensing and recording of activity of one or more electrically excitable cells in a target region are also provided.

摘要翻译： 用于无目的地感测和记录目标区域中的一个或多个可激发细胞的活性的系统包括至少一个无阻塞探针。 每个无阻抗探针包括至少一个被配置为电耦合到目标区域的信号检测器，测量一个或多个可电激活细胞的活性，并响应于一个或多个可电激活细胞的活性产生电信号， 以及至少一个光源，电耦合到所述至少一个信号检测器，以接收所述电信号并发射表示所述一个或多个可电激活细胞的活性的光信号。 还提供了用于无目的地感测和记录目标区域中一个或多个可电激活细胞的活性的方法。