专利检索 ap:("The Trustees of the University of Pennsylvania" OR "University of Georgia Research Foundation, Inc.") AND inv:"Donald A. HARN, JR." 第 1 页

1.

发明申请
LISTERIA-BASED ADJUVANTS 审中-公开
标题翻译：基于LISTERIA的ADJUVANTS

公开(公告)号：US20160324903A1

公开(公告)日：2016-11-10

申请号：US15220641

申请日：2016-07-27

申请人： ADVAXIS, INC. , THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA , UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.

发明人： John ROTHMAN , Anu WALLECHA , Reshma SINGH , Donald A. HARN, JR. , Yvonne PATERSON

IPC分类号： A61K35/74 , C12N7/00 , A61K39/39 , A61K39/00 , A61K45/06 , A61K39/12

CPC分类号： A61K35/74 , A61K39/0011 , A61K39/0208 , A61K39/12 , A61K39/39 , A61K45/06 , A61K2039/522 , A61K2039/523 , A61K2039/55594 , A61K2039/585 , C12N7/00 , C12N2710/20034

摘要： This invention provides methods and compositions for using Listeria monocytogenes as an adjuvant for enhancing immune responses in a subject.

摘要翻译： 本发明提供了使用单核细胞增生利斯特氏菌作为佐剂以增强受试者的免疫应答的方法和组合物。

2.

发明申请
USE OF LISTERIA VACCINE VECTORS TO REVERSE VACCINE UNRESPONSIVENESS IN PARASITICALLY INFECTED INDIVIDUALS 有权

公开(公告)号：US20160256538A1

公开(公告)日：2016-09-08

申请号：US14877601

申请日：2015-10-07

申请人： The Trustees of the University of Pennsylvania , University of Georgia Research Foundation, Inc.

发明人： Donald A. HARN, JR. , Yvonne Paterson , Lisa McEwen

IPC分类号： A61K39/21 , A61K39/00

CPC分类号： A61K39/21 , A61K39/00 , A61K39/0003 , A61K39/12 , A61K2039/523 , A61K2039/54 , A61K2039/577 , C12N2710/20034 , C12N2740/16034 , Y02A50/41 , Y02A50/412 , Y02A50/423

摘要： This invention relates to methods of using a Listeria vaccine vector to induce a Th1 immune response in subjects having persistent Th2 immune response profiles.