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    METHOD FOR REGENERATING CARTILAGE
    3.
    发明申请
    METHOD FOR REGENERATING CARTILAGE 有权
    再生培养方法

    公开(公告)号：US20070098759A1

    公开(公告)日：2007-05-03

    申请号：US11564012

    申请日：2006-11-28

    申请人： Theodore Malinin

    发明人： Theodore Malinin

    IPC分类号： A61F2/00

    CPC分类号： A61L27/3654 ,  A61L27/3612 ,  A61L27/3691

    摘要： Disclosed is a method for regenerating articular cartilage in an animal comprising administering a therapeutically effective amount of a non-demineralized particulate articular cartilage having a distribution of particle sizes within the range of from about 60 microns to about 500 microns.

    摘要翻译： 公开了一种用于在动物中再生关节软骨的方法，包括施用治疗有效量的具有约60微米至约500微米范围内的粒度分布的非软化粒状关节软骨。

    BONE PUTTY AND GEL SYSTEMS AND METHODS
    4.
    发明申请
    BONE PUTTY AND GEL SYSTEMS AND METHODS 审中-公开

    公开(公告)号：US20170112963A1

    公开(公告)日：2017-04-27

    申请号：US14923057

    申请日：2015-10-26

    申请人： Theodore Malinin

    发明人： Theodore Malinin

    IPC分类号： A61L27/36 ,  A61L27/24

    摘要： A collagen-bone composition may include bone collagen and bone particles. The collagen may be in the form of a collagen suspension and the bone particles may be demineralized bone particles retained in collagen suspension. The composition may be prepared from pressure and thermal treatment of dry demineralized bone particles contacted with an aqueous medium to produce a viscous gel-like fluid. The fluid may include the collagen extracted from the demineralized bone particles. Addition of particulate bone may be used to increase the consistency of the composition, which may convert it into a paste or putty. The paste or putty may be suitable for ejection from a syringe. The collagen-bone composition may be preserved by freeze-drying or preferably by hypothermic dehydration. On reconstitution with aqueous medium, the preserved material may resume its original shape and properties.

    Thin bendable bone plate for bone deficit repair and method of preparation
    5.
    发明授权
    Thin bendable bone plate for bone deficit repair and method of preparation 有权
    用于骨缺损修复的薄弯骨骨板及其制备方法

    公开(公告)号：US08888823B1

    公开(公告)日：2014-11-18

    申请号：US14173495

    申请日：2014-02-05

    申请人： Theodore Malinin

    发明人： Theodore Malinin

    IPC分类号： A61B17/80

    CPC分类号： A61B17/8085 ,  A61B2017/00526 ,  A61L31/005 ,  A61L31/146 ,  A61L2430/02 ,  Y10T83/0405

    摘要： A flexible, bendable organic decalcified or partially decalcified bone, cortical or cancellous, adapted for use in augmentation or repair of animal skeletal structures comprising a continuous plate or sheet of natural bone, as well as dermis is described. The thickness, flexibility and tensile strength of the construct is such as to allow it to be shaped and contoured without damage to it. The composition is ultimately remodeled by the body, thus obviating the need for additional surgical intervention. The clinical indications for the use of the invented construct are many, but are particularly prominent in dentistry, oral and maxillofacial surgery and implantology. It is particularly useful in the maxillary sinus augmentation. A unique new method, different from previously described methods for the preparation of the disclosed constructs, is described.

    摘要翻译： 描述适用于增强或修复包括天然骨的连续板或片的动物骨骼结构以及真皮的柔性的，可弯曲的有机脱钙或部分脱钙的骨，皮层或松质骨。 构造物的厚度，柔韧性和拉伸强度使得其可以成形和成型而不损坏其。 组合物最终被身体重塑，从而避免了额外的手术干预的需要。 使用本发明构造物的临床适应症很多，但在牙科，口腔和颌面外科学和种植学中尤为突出。 它在上颌窦扩大中特别有用。 描述了与用于制备所公开的构建体的先前描述的方法不同的独特的新方法。

    Method for regenerating cartilage
    6.
    发明授权
    Method for regenerating cartilage 有权
    软骨再生方法

    公开(公告)号：US07838040B2

    公开(公告)日：2010-11-23

    申请号：US11564012

    申请日：2006-11-28

    申请人： Theodore Malinin

    发明人： Theodore Malinin

    IPC分类号： A61K35/34

    CPC分类号： A61L27/3654 ,  A61L27/3612 ,  A61L27/3691

    摘要： Disclosed is a method for regenerating articular cartilage in an animal comprising administering a therapeutically effective amount of a non-demineralized particulate articular cartilage having a distribution of particle sizes within the range of from about 60 microns to about 500 microns.

    摘要翻译： 公开了一种用于在动物中再生关节软骨的方法，包括施用治疗有效量的具有约60微米至约500微米范围内的粒度分布的非软化粒状关节软骨。

    TREATED OSSEOUS PARTICULATE FLUFF COMPOSITION
    7.
    发明申请
    TREATED OSSEOUS PARTICULATE FLUFF COMPOSITION 有权

    公开(公告)号：US20220008614A1

    公开(公告)日：2022-01-13

    申请号：US16922422

    申请日：2020-07-07

    申请人： Theodore Malinin

    发明人： Theodore Malinin

    IPC分类号： A61L27/36

    摘要： A method of making a bone graft composition is described wherein material including decalcified bone elongated particulate bone is dried in a constraining device or under pressure to produce a solid construct having dimensions corresponding to the constraining device or space to which the material occupied under pressure.

    Thin bendable bone plate for bone deficit repair and method of preparation
    8.
    发明授权
    Thin bendable bone plate for bone deficit repair and method of preparation 有权
    用于骨缺损修复的薄弯骨骨板及其制备方法

    公开(公告)号：US09101424B1

    公开(公告)日：2015-08-11

    申请号：US14543234

    申请日：2014-11-17

    申请人： Theodore Malinin

    发明人： Theodore Malinin

    IPC分类号： A61B17/80

    CPC分类号： A61B17/8085 ,  A61B2017/00526 ,  A61L31/005 ,  A61L31/146 ,  A61L2430/02 ,  Y10T83/0405

    摘要： A flexible, bendable organic decalcified or partially decalcified bone, cortical or cancellous, adapted for use in augmentation or repair of animal skeletal structures comprising a continuous plate or sheet of natural bone, as well as dermis is described. The thickness, flexibility and tensile strength of the construct is such as to allow it to be shaped and contoured without damage to it. The composition is ultimately remodeled by the body, thus obviating the need for additional surgical intervention. The clinical indications for the use of the invented construct are many, but are particularly prominent in dentistry, oral and maxillofacial surgery and implantology. It is particularly useful in the maxillary sinus augmentation. A unique new method, different from previously described methods for the preparation of the disclosed constructs, is described.

    摘要翻译： 描述适用于增强或修复包括天然骨的连续板或片的动物骨骼结构以及真皮的柔性的，可弯曲的有机脱钙或部分脱钙的骨，皮层或松质骨。 构造物的厚度，柔韧性和拉伸强度使得其可以成形和成型而不损坏其。 组合物最终被身体重塑，从而避免了额外的手术干预的需要。 使用本发明构造物的临床适应症很多，但在牙科，口腔和颌面外科学和种植学中尤为突出。 它在上颌窦扩大中特别有用。 描述了与用于制备所公开的构建体的先前描述的方法不同的独特的新方法。