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25 条记录 (耗时 0.017 秒)

    Bone putty and gel systems and methods
    1.
    发明授权
    Bone putty and gel systems and methods 有权

    公开(公告)号：US10549011B2

    公开(公告)日：2020-02-04

    申请号：US14923057

    申请日：2015-10-26

    申请人： Theodore Malinin

    发明人： Theodore Malinin

    IPC分类号： A61L27/36 ,  A61L27/24

    摘要： A collagen-bone composition may include bone collagen and bone particles. The collagen may be in the form of a collagen suspension and the bone particles may be demineralized bone particles retained in collagen suspension. The composition may be prepared from pressure and thermal treatment of dry demineralized bone particles contacted with an aqueous medium to produce a viscous gel-like fluid. The fluid may include the collagen extracted from the demineralized bone particles. Addition of particulate bone may be used to increase the consistency of the composition, which may convert it into a paste or putty. The paste or putty may be suitable for ejection from a syringe. The collagen-bone composition may be preserved by freeze-drying or preferably by hypothermic dehydration. On reconstitution with aqueous medium, the preserved material may resume its original shape and properties.

    Bioactive Implants and Methods of Making and Using
    3.
    发明申请
    Bioactive Implants and Methods of Making and Using 审中-公开

    公开(公告)号：US20170128633A1

    公开(公告)日：2017-05-11

    申请号：US14937206

    申请日：2015-11-10

    申请人： Theodore Malinin

    发明人： Theodore Malinin

    IPC分类号： A61L31/16 ,  A61L31/04

    CPC分类号： A61L27/3608 ,  A61L27/3612 ,  A61L27/50 ,  A61L27/54 ,  A61L2300/106 ,  A61L2300/404 ,  A61L2430/02 ,  A61L2430/06

    摘要： The present application relates to bioactive implants, methods of making bioactive implants, and methods of using bioactive implants to treat or repair a bone defect or a cartilage defect. In an aspect, the present application relates to compositions comprising bone microparticles in a solution, wherein the compositions harden upon desiccation into bioactive implants. In an aspect, the present application relates to compositions comprising cartilage microparticles in a solution, wherein the compositions harden upon desiccation into bioactive implants. In an aspect, disclosed herein are methods of making and using the disclosed compositions comprising bone microparticles and the disclosed composition comprising cartilage microparticles. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

    COMPOSITE BONE GRAFTS, PARTICULATE BONE-CALCIUM SULFATE CONSTRUCTS, AND METHODS OF TREATING JOINT INJURIES
    4.
    发明申请
    COMPOSITE BONE GRAFTS, PARTICULATE BONE-CALCIUM SULFATE CONSTRUCTS, AND METHODS OF TREATING JOINT INJURIES 审中-公开
    复合骨块，粒状硫酸钙结构及治疗关节损伤的方法

    公开(公告)号：US20110208305A1

    公开(公告)日：2011-08-25

    申请号：US13057918

    申请日：2009-08-05

    申请人： Theodore Malinin ,  Temple H. Thomas

    发明人： Theodore Malinin ,  Temple H. Thomas

    IPC分类号： A61F2/08 ,  A61F2/28

    CPC分类号： A61F2/08 ,  A61F2/0811 ,  A61F2002/087 ,  A61F2002/0882 ,  A61F2002/2839 ,  A61F2002/3021 ,  A61F2002/30276 ,  A61F2230/0067 ,  A61F2230/0086

    摘要： A solid implantable bone construct (12) shaped like a cylinder, a cone, or a frustum, for anchoring ligament implants. The bone construct (12) can include a bone component and a biocompatible solid component. The bone component can include particulate bone of between 75 and 600 microns, powdered bone of 75 microns or smaller in size, or both. The biocompatible solid component can include calcium sulfate hemihydrate, a calcium phosphate product, or both. The bone component can be between 5 and 50 wt-% of the construct (12) and the biocompatible solid component can be at least 50 wt-% of the construct (12). Also disclosed is a composite graft (10) comprising a first bone dowel (12) and a ligament (20) and a method of securing one bone to another using the composite graft (10).

    摘要翻译： 固定的可植入骨构件（12），其形状像圆柱体，锥体或截头锥体，用于锚定韧带植入物。 骨构建体（12）可以包括骨组分和生物相容性固体组分。 骨组件可以包括75至600微米之间的颗粒骨，尺寸为75微米或更小的粉末骨，或两者均为。 生物相容的固体组分可以包括半水合硫酸钙，磷酸钙产品，或两者。 骨组分可以是构建体（12）的5至50重量％，并且生物相容性固体组分可以是构建体（12）的至少50重量％。 还公开了包括第一骨榫（12）和韧带（20）的复合移植物（10）和使用复合移植物（10）将一个骨骼固定到另一个骨骼的方法。

    Treatment of distilled alcoholic liquors
    7.
    发明授权
    Treatment of distilled alcoholic liquors 失效
    蒸馏酒精液的处理

    公开(公告)号：US3698913A

    公开(公告)日：1972-10-17

    申请号：US3698913D

    申请日：1970-09-11

    申请人： THEODORE MALININ

    发明人： MALININ THEODORE

    IPC分类号： C12H1/14 ,  C12F1/00 ,  C12G3/12

    CPC分类号： C12H1/14

    摘要： A METHOD FOR IMPROVING AND MELLOWING THE TASTE OF ALCOHOLIC DISTILLED LIQUORS AND FOR BRINGING ABOUT A SHIFT IN THE PH VALUE TOWARD THE NEUTRAL RANGE, BY REDUCING THE TOTAL ESTER CONTENT AND TOTAL FUSEL OIL CONTENT, INVOLVES INTIMATELY CONTACTING THE LIQUOR WITH A GASEOUS MIXTURE OF OXYGEN AND CARBON DIOXIDE IN WHICH THE PERCENT OF CARBON DIOXIDE BY VOLUME IS IN THE RANGE FROM ABOUT 5% TO ABOUT 15%.

    METHOD FOR REGENERATING CARTILAGE
    10.
    发明申请
    METHOD FOR REGENERATING CARTILAGE 有权
    再生培养方法

    公开(公告)号：US20070098759A1

    公开(公告)日：2007-05-03

    申请号：US11564012

    申请日：2006-11-28

    申请人： Theodore Malinin

    发明人： Theodore Malinin

    IPC分类号： A61F2/00

    CPC分类号： A61L27/3654 ,  A61L27/3612 ,  A61L27/3691

    摘要： Disclosed is a method for regenerating articular cartilage in an animal comprising administering a therapeutically effective amount of a non-demineralized particulate articular cartilage having a distribution of particle sizes within the range of from about 60 microns to about 500 microns.

    摘要翻译： 公开了一种用于在动物中再生关节软骨的方法，包括施用治疗有效量的具有约60微米至约500微米范围内的粒度分布的非软化粒状关节软骨。