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公开(公告)号：US07806029B2
公开(公告)日：2010-10-05
申请号：US11454555
申请日：2006-06-16
申请人： Thierry Rozot , Kenneth W. Wright
发明人： Thierry Rozot , Kenneth W. Wright
CPC分类号： B23K26/032 , B22D11/1265 , B23K7/003 , B23K7/10 , B23K7/102 , B23K26/03 , B23K26/38 , B23K37/08 , B24B9/04 , Y10T83/04 , Y10T83/0524 , Y10T83/088 , Y10T83/364 , Y10T83/505 , Y10T83/533 , Y10T83/828 , Y10T83/849 , Y10T83/929 , Y10T83/9372
摘要： A slab shaping system includes a slab shaping device. The slab shaping device includes a cutting device and de-burring device, wherein the cutting device and the de-burring device, respectively cut and de-burr a slab. According to an embodiment, the slab shaping system may include a plurality of spaced apart slab support beams that form at least one slot therebetween. According to an embodiment, the cutting device and de-burring device may be axially-aligned. A method for operating a slab shaping system is disclosed. The method includes the steps of positioning a plurality of slab support beams on a table to form at least one slot; positioning a slab over the slab support beams; positioning a cutting device and de-burring device of a slab shaping device in axial-alignment; and cutting and de-burring the cut in the slab along a length of the at least one slot.
摘要翻译： 板坯成型系统包括板坯成形装置。 板坯成型装置包括切割装置和去毛刺装置，其中切割装置和去毛刺装置分别切割和去毛刺板坯。 根据一个实施例，板坯成形系统可以包括多个间隔开的平板支撑梁，其在它们之间形成至少一个槽。 根据实施例，切割装置和去毛刺装置可以是轴向对准的。 公开了一种操作板坯成型系统的方法。 该方法包括以下步骤：将多个平板支撑梁定位在台上以形成至少一个槽; 将板坯定位在板坯支撑梁上; 将板坯成形装置的切割装置和去毛刺装置定位在轴向对准中; 以及沿所述至少一个槽的长度切割和去除所述板坯中的切口。
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公开(公告)号：US20100263507A1
公开(公告)日：2010-10-21
申请号：US12794973
申请日：2010-06-07
申请人： Thierry Rozot , Kenneth W. Wright
发明人： Thierry Rozot , Kenneth W. Wright
CPC分类号： B23K26/032 , B22D11/1265 , B23K7/003 , B23K7/10 , B23K7/102 , B23K26/03 , B23K26/38 , B23K37/08 , B24B9/04 , Y10T83/04 , Y10T83/0524 , Y10T83/088 , Y10T83/364 , Y10T83/505 , Y10T83/533 , Y10T83/828 , Y10T83/849 , Y10T83/929 , Y10T83/9372
摘要： A slab shaping system includes a slab shaping device. The slab shaping device includes a cutting device and de-burring device, wherein the cutting device and the de-burring device, respectively cut and de-burr a slab. According to an embodiment, the slab shaping system may include a plurality of spaced apart slab support beams that form at least one slot therebetween. According to an embodiment, the cutting device and de-burring device may be axially-aligned. A method for operating a slab shaping system is disclosed. The method includes the steps of positioning a plurality of slab support beams on a table to form at least one slot; positioning a slab over the slab support beams; positioning a cutting device and de-burring device of a slab shaping device in axial-alignment; and cutting and de-burring the cut in the slab along a length of the at least one slot.
摘要翻译： 板坯成型系统包括板坯成形装置。 板坯成型装置包括切割装置和去毛刺装置，其中切割装置和去毛刺装置分别切割和去毛刺板坯。 根据一个实施例，板坯成形系统可以包括多个间隔开的平板支撑梁，其在它们之间形成至少一个槽。 根据实施例，切割装置和去毛刺装置可以是轴向对准的。 公开了一种操作板坯成型系统的方法。 该方法包括以下步骤：将多个平板支撑梁定位在台上以形成至少一个槽; 将板坯定位在板坯支撑梁上; 将板坯成形装置的切割装置和去毛刺装置定位在轴向对准中; 以及沿所述至少一个槽的长度切割和去除所述板坯中的切口。
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公开(公告)号：US08974814B2
公开(公告)日：2015-03-10
申请号：US12269838
申请日：2008-11-12
IPC分类号： A61K9/70 , A01N25/34 , A61K31/155 , A61K9/00 , A61K31/4164 , A61K31/496 , A61K31/505 , A61K31/5365 , A61K31/56 , A61K31/65 , A61K31/7008 , A61K31/7052 , A61K38/00
CPC分类号： A61K31/155 , A61K9/0051 , A61K9/70 , A61K31/4164 , A61K31/496 , A61K31/505 , A61K31/5365 , A61K31/56 , A61K31/65 , A61K31/7008 , A61K31/7052 , A61K38/00
摘要： The present invention is directed generally to a layered polymeric monofilament fiber drug delivery device, where each layer of the device can contain a different polymer, drug, additive, or any combination or mixture thereof. The layered nature of the current monofilament polymeric monofilament device provides the capability to modulate the release of one or more drugs and/or the mechanical properties of the fiber so that drug release and device failure can be separately tuned to provide for the tailored introduction of therapeutically effective drugs or agents to a target tissue. Moreover, the fiber may comprise more than one distinct segments along its length, each segment itself having different combinations and/or numbers of layers thereby providing even greater freedom in the design of the therapeutic delivery device. The invention is also directed to a method of manufacturing such a layered polymeric monofilament fiber drug delivery device, and methods of treatment using such devices.
摘要翻译： 本发明一般涉及层状聚合物单丝纤维药物递送装置，其中该装置的各层可包含不同的聚合物，药物，添加剂或其任何组合或混合物。 当前单丝聚合单丝装置的分层性质提供了调节纤维的一种或多种药物释放和/或机械性能的能力，使得药物释放和装置故障可以被单独调节以提供定制的治疗引入 有效的药物或药剂到目标组织。 此外，纤维可以沿其长度包括多于一个不同的片段，每个片段本身具有不同的组合和/或层数，从而在治疗递送装置的设计中提供更大的自由度。 本发明还涉及制造这种层状聚合物单丝纤维药物递送装置的方法，以及使用这种装置的处理方法。
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公开(公告)号：USD535744S1
公开(公告)日：2007-01-23
申请号：US29234314
申请日：2005-07-18
申请人： Kenneth W. Wright
设计人： Kenneth W. Wright
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5.发明授权Apparatus and methods for marking the visual center of the cornea of a human eye 失效用于标记人眼角膜视觉中心的装置和方法
公开(公告)号：US4875767A
公开(公告)日：1989-10-24
申请号：US163799
申请日：1988-03-03
申请人： Kenneth W. Wright
发明人： Kenneth W. Wright
CPC分类号： A61B3/15 , A61F9/0136 , A61B2090/3937
摘要： An apparatus for identifying and marking the visual center of the cornea of a human eye includes a cylindrical tube for placement over the cornea of a human eye. The tube is open at one end and includes, inside the tube, a disk-shaped member having a central pinhole-sized opening near the open end of the tube. Farther from the open end of the tube are one or more illuminated disks having central pinhole-sized opacities, one in the shape of a ring, another in the shape of a dot. While a viewer focuses through the pinhole on these opacities, a movable member mounted coaxially with the tube is moved to engage and mark the central visual axis of the cornea.
摘要翻译： 用于识别和标记人眼角膜的视觉中心的装置包括用于放置在人眼角膜上的圆柱形管。 该管在一端开口并且在管内部包括在管的开口端附近具有中心针孔尺寸的开口的盘形构件。 距离管的开口端更远的是具有中心针孔大小不透明度的一个或多个照明盘，一个呈环状，另一个为点状。 当观察者通过针孔聚焦在这些不透明度上时，与管同轴安装的可移动构件被移动以接合并标记角膜的中心视轴。
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公开(公告)号：US20100287293A1
公开(公告)日：2010-11-11
申请号：US12463127
申请日：2009-05-08
申请人： Kenneth W. Wright , John S. Lear , John E. Stem , Robert Harrover , Julian Zottl
发明人： Kenneth W. Wright , John S. Lear , John E. Stem , Robert Harrover , Julian Zottl
CPC分类号： G06F17/30548
摘要： According to particular embodiments, a system for outputting prerecorded communications includes a central server that receives playback instructions, retrieves event data from a database according to the playback instructions, and outputs events from the event data to an agent server according to the timing characteristics associated with the events, and the agent server that deploys playback agents into the target group communication service to submit events to the target group communication service.
摘要翻译： 根据特定实施例，用于输出预先记录的通信的系统包括接收回放指令的中央服务器，根据回放指令从数据库检索事件数据，并且根据与...相关的定时特性从事件数据向代理服务器输出事件 事件和将回放代理部署到目标组通信服务中以将事件提交给目标组通信服务的代理服务器。
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公开(公告)号：US07717363B2
公开(公告)日：2010-05-18
申请号：US12151659
申请日：2008-05-08
申请人： Mark E. Davis , Kenneth W. Wright , Ryan K. Zeidan
发明人： Mark E. Davis , Kenneth W. Wright , Ryan K. Zeidan
CPC分类号： A61L27/14 , A61K6/08 , A61L17/10 , A61L17/145 , A61L27/34 , A61L27/50 , A61L27/58 , A61L31/10 , A61L31/148 , C08G63/68 , C08G63/688 , C08L101/16
摘要： The present invention provides polymers which substantially degrade in the presence of one or more triggers, preferably light energy or hydrogen peroxide, but does not substantially degrade in the absence of one or more triggers.
摘要翻译： 本发明提供了在一种或多种触发剂，优选光能或过氧化氢的存在下基本上降解但在不存在一种或多种触发剂的情况下基本上不降解的聚合物。
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公开(公告)号：US5474258A
公开(公告)日：1995-12-12
申请号：US244252
申请日：1994-05-20
CPC分类号： B64D27/26 , B64D2027/266
摘要： A gas turbine engine 10 is suspended via a casing 15 from a pylon 12 by a front mount 20 and a rear mount 40. The front mount 20 comprises a bracket 22, having a plurality of pins 26,28 and 30 integral therewith, which is bolted to the underside 11 of the pylon 12. The first pin 26 engages an annular flange 16 around the casing 15 to support the engine 10 in a vertical plane. Any vertical loads act peripherally of the casing 15 through the annular flange 16 to minimise the distortion of the casing 15. The second pin 28 engages with the casing 15 directly to prevent axial and lateral movement of the engine 10 relative to the pylon 12. The third pin 30 is provided as a failsafe. In normal operation the third pin 30 carries no load, however if the first pin 26 should break the third pin 30 then supports the engine 10 in a vertical plane. Any vertical loads then act peripherally of the engine casing 15 through an annular flange 18.
摘要翻译： PCT No.PCT / GB92 / 01576 Sec。 371日期1994年5月20日 102（e）日期1994年5月20日PCT提交1992年8月28日PCT公布。 公开号WO93 / 11041 日期：1993年6月10日。燃气涡轮发动机10经由外壳15通过前安装件20和后安装件40从吊架12悬挂。前安装件20包括托架22，托架22具有多个销26,28 30与螺栓连接到塔架12的下侧11。第一销26接合围绕壳体15的环形凸缘16，以将发动机10支撑在垂直平面内。 任何垂直的载荷通过环形凸缘16作用在壳体15周围，以最小化壳体15的变形。第二销28直接与壳体15接合，以防止发动机10相对于塔架12的轴向和横向运动。 第三销30被设置为故障保护。 在正常操作中，第三销30没有载荷，但是如果第一销26应该打破第三销30，则在垂直平面上支撑发动机10。 任何垂直载荷然后通过环形凸缘18作用于发动机壳体15的周边。
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公开(公告)号：US4662869A
公开(公告)日：1987-05-05
申请号：US672930
申请日：1984-11-19
申请人： Kenneth W. Wright
发明人： Kenneth W. Wright
CPC分类号： A61F9/00763 , A61B2017/00544
摘要： A precision intraocular surgical tool for removal or severing and removal of tissue from the eyeball of a patient includes a first tube of very small diameter having a port near one end, with the port including a tissue-shearing portion and, towards the closed end of the tube, a portion of substantially smaller size than the tissue-shearing portion, and a second tube concentric with the first tube. The first and second tubes fit snugly together, and one of the tubes is slidable with respect to the other. The end of the second tube adjacent to the port has a sharp cutting edge portion, and may also include a second smooth portion. The tool includes a mechanism for drawing tissue into the port for moving one of the tubes so that the sharp cutting edge portion can cross the port and cut tissue sucked into the port or, alternatively, so that the opening in the port can be restricted to the smaller-sized portion for aspirating tissue from the eyeball of a patient without cutting such tissue.
摘要翻译： 用于从患者眼球去除或切除和去除组织的精密眼内窥镜工具包括具有近端的近端直径非常小的第一管，端口包括组织剪切部分，并且朝向封闭端 所述管是比组织剪切部分小得多的部分，以及与第一管同心的第二管。 第一和第二管子紧密地配合在一起，其中一个管子可以相对于另一个管子滑动。 邻近端口的第二管的端部具有尖锐的切削刃部分，并且还可以包括第二平滑部分。 该工具包括用于将组织抽出到端口中以移动管中的一个的机构，使得锋利的切割边缘部分可以穿过端口并切割被吸入端口中的组织，或者替代地使得端口中的开口可以被限制到 较小尺寸的部分用于从患者的眼球吸出组织而不切割这种组织。
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公开(公告)号：US20170224774A1
公开(公告)日：2017-08-10
申请号：US15425872
申请日：2017-02-06
申请人： Kenneth W. Wright
发明人： Kenneth W. Wright
CPC分类号： A61K38/1866 , A61B3/12 , A61B3/14 , A61K9/0019
摘要： Disclosed herein is a method for administering systemic (e.g., by intravenous injection) supplemental vascular endothelial growth factor (VEGF) to premature infants to prevent the disease sequelae and complications including but not limited to retinopathy of prematurity (ROP) and/or paraventricular leukomalacia (PVL) and/or bronchopulmonary dysplasia (BPD) associated with premature births. The VEGF is administered to the premature infant to produce a physiologic serum VEGF level that is substantially similar to the VEGF level found in a normally developing fetus in the utero. By way of one example, the retinal blood vessel growth of the premature infant is monitored, and the administration of VEGF is terminated when the infant's retinal blood vessels are substantially fully grown to ROP Zone 3. By virtue of the method herein disclosed, normal vessel growth occurs, and lung disease, ROP with blindness, brain damage and other diseases associated with premature birth are substantially avoided.
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