公开(公告)号：US07283878B2

公开(公告)日：2007-10-16

申请号：US10963184

申请日：2004-10-12

申请人： Thomas D. Brostrom ,  Ryan T. Bauer ,  Douglas S. Hine

发明人： Thomas D. Brostrom ,  Ryan T. Bauer ,  Douglas S. Hine

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N1/057 ,  A61N2001/0578

摘要： A lead stabilization and extension wire that enables the withdrawal of a guide catheter over an electrical medical lead body without dislodging an electrode or sensor from an implantation site or detaching the fixation mechanism and methods of use and a kit are disclosed. The lead stabilizer and retraction wire comprises a wire sheath and an elongated core wire insertable within a sheath lumen. The sheath is insertable within a lead body lumen and includes a movable lead clamp that can engage with a lead connector element and a friction element frictionally engaging the core wire to maintain the extension wire length. The lead stabilizer and retraction wire is insertable into the lead body lumen enabling retraction of the guide catheter over the lead stabilization and extension wire while force is applied through the lead stabilization and extension wire to maintain the distal electrode at the implantation site.

摘要翻译： 公开了一种引线稳定和延伸线，其能够引导导管在电学医疗引线主体上取出，而不会从植入部位移除电极或传感器，或者分离固定机构以及使用方法和试剂盒。 引线稳定器和回缩线包括线鞘和可插入鞘管内的细长芯线。 护套可插入引线体腔内并且包括可移动引线夹，其可与引线连接器元件接合，摩擦元件与芯线摩擦接合以保持延长线长度。 引导稳定器和收回线可插入引线体腔，从而能够使引导导管缩回到引线稳定和延伸线上，同时通过引线稳定和延伸线施加力，以将远端电极保持在植入位置。

公开(公告)号：US20120130466A1

公开(公告)日：2012-05-24

申请号：US13301587

申请日：2011-11-21

申请人： John L. Sommer ,  Douglas S. Hine

发明人： John L. Sommer ,  Douglas S. Hine

IPC分类号： A61N1/04

CPC分类号： H01R31/06 ,  A61N1/3752 ,  H01R13/5224 ,  H01R27/00 ,  H01R2201/12

摘要： A lead connector is terminated proximally by a connector pin and includes a circumferential array of connector pads, each connector pad coupled to an electrode via an elongated insulated conductor. A lumen of an adaptor is adapted to engage the lead connector and includes an electrical contact zone formed therein and positioned for coupling with a one of the array of connector pads, when the connector is engaged within the lumen, in order to facilitate electrical connection of a selected electrode corresponding to the one of the array of connector pads.

摘要翻译： 引线连接器由连接器针靠近端接，并且包括连接器焊盘的圆周阵列，每个连接器焊盘通过细长的绝缘导体耦合到电极。 适配器的内腔适于接合引线连接器并且包括形成在其中的电接触区域，并且当连接器接合在内腔内时，该内部定位成与连接器焊盘阵列中的一个连接，以便于电连接 选择的电极对应于所述连接器焊盘阵列中的一个。

公开(公告)号：US07386351B2

公开(公告)日：2008-06-10

申请号：US10136777

申请日：2002-04-30

申请人： Douglas S. Hine ,  John L. Sommer ,  James H. Vaughan ,  Rick D. McVenes ,  Paulus C Van Venrooij ,  Pierre-Andre Grandjean

发明人： Douglas S. Hine ,  John L. Sommer ,  James H. Vaughan ,  Rick D. McVenes ,  Paulus C Van Venrooij ,  Pierre-Andre Grandjean

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61F2/88 ,  A61F2/958 ,  A61N2001/0585

摘要： A medical electrical lead, which may be useful in coupling an implantable medical device, is comprised of a first and second lead. The first lead has a first electrode coupled adjacent a distal end portion thereof. The distal end portion of the first lead is anchorable in the coronary sinus of a patient. The second lead is coupled with and moveable along the first lead. The second lead has a second electrode located thereon wherein the position of the first and second electrodes may be varied relative to one another by movement of the second lead along the first lead. A rubber tip holds the relative position of each electrode.

摘要翻译： 可用于联接可植入医疗装置的医用电引线由第一和第二引线组成。 第一引线具有邻近其远端部分耦合的第一电极。 第一引线的远端部分可锚定在患者的冠状窦中。 第二个领先者与第一个领先者相结合并可以移动。 第二引线具有位于其上的第二电极，其中第一和第二电极的位置可以通过第二引线沿着第一引线的移动而相对于彼此变化。 橡胶尖端保持每个电极的相对位置。

公开(公告)号：US06836687B2

公开(公告)日：2004-12-28

申请号：US10131388

申请日：2002-04-25

申请人： James F. Kelley ,  James H. Vaughn ,  Stanten C. Spear ,  Douglas S. Hine ,  Kenneth C. Gardeski ,  Vicki L. Bjorklund ,  Pedro A. Meregotte ,  John L. Sommer ,  John J. Maier

发明人： James F. Kelley ,  James H. Vaughn ,  Stanten C. Spear ,  Douglas S. Hine ,  Kenneth C. Gardeski ,  Vicki L. Bjorklund ,  Pedro A. Meregotte ,  John L. Sommer ,  John J. Maier

IPC分类号： A61N105

CPC分类号： A61M25/0138 ,  A61B18/1492 ,  A61B2017/22038 ,  A61M25/005 ,  A61M25/0054 ,  A61M25/0141 ,  A61M25/0147 ,  A61M25/0668 ,  A61M39/0613 ,  A61M2025/0042 ,  A61M2025/0047 ,  A61M2025/0081 ,  A61M2025/0161 ,  A61M2025/0681 ,  A61M2025/1052 ,  A61M2025/1079 ,  A61N1/05 ,  A61N1/056 ,  A61N2001/0578 ,  A61N2001/0585

摘要： A system for delivering a medical electrical lead within a coronary venous system that includes an introducer kit for establishing venous access to the coronary venous system and a plurality of delivery sheaths, each corresponding to a desired approach to a coronary sinus of the coronary venous system and insertable within the coronary venous system through the navigation pathway. A hemostasis valve is coupled to a delivery sheath of the plurality of delivery sheaths, and a guide wire is inserted within the lead lumen, guiding delivery of the distal tip of the medical electrical lead to a target site within the coronary venous system through the hemostasis valve and the delivery sheath. Subsequent to the distal tip being delivered to the target sight, the hemostasis valve is advanced over the connector of the medical electrical lead to remove the hemostasis valve from the medical electrical lead.

摘要翻译： 一种用于在冠状静脉系统内递送医用电线的系统，其包括用于建立对冠状静脉系统的静脉通路的引导器套件和多个输送护套，每个输送护套对应于冠状静脉系统的冠状窦所需的方法， 通过导航路径插入冠状静脉系统内。 止血阀联接到多个输送护套的输送护套，并且引导线插入引导腔内，通过止血将医用电导线的远端引导到冠状静脉系统内的靶位点 阀门和输送护套。 在远端尖端被传送到目标瞄准器之后，止血阀在医用电线的连接器上前进，以从医用电引线上除去止血阀。

公开(公告)号：US07769451B2

公开(公告)日：2010-08-03

申请号：US11116547

申请日：2005-04-28

申请人： Zhongping Yang ,  Mark A. Hjelle ,  Douglas S. Hine

发明人： Zhongping Yang ,  Mark A. Hjelle ,  Douglas S. Hine

IPC分类号： A61N1/365 ,  A61B5/05

CPC分类号： A61N1/36557 ,  A61N1/056 ,  A61N1/3627 ,  A61N1/36564

摘要： In some embodiments, a method for optimizing cardiac resynchronization therapy (CRT) may include one or more of the following steps: (a) conducting a baseline measurement of a physical parameter of a patient before initiating CRT, (b) performing an implantation process including implanting a pacing device and pacing leads in the patient, the pacing device and pacing leads for providing the CRT, (c) initiating CRT on the patient, (d) measuring the physical parameter of the patient after initiation of the CRT, (e) comparing the measured physical parameter after initiation of the CRT to the baseline measure of the physical parameter to analyze the patient's response to the CRT, (f) adjusting the CRT during the implantation process to try and improve the patient's response to the CRT, and (g) repositioning at least one of the patient leads during the implantation process to try and improve the patient's response to the CRT.

摘要翻译： 在一些实施例中，用于优化心脏再同步治疗（CRT）的方法可以包括以下步骤中的一个或多个：（a）在开始CRT之前对患者的物理参数进行基线测量，（b）执行植入过程，包括 将起搏装置和起搏引线植入患者体内，起搏装置和起搏引线用于提供CRT，（c）在患者身上启动CRT，（d）在CRT开始后测量患者的物理参数，（e） 将CRT开始后的测量物理参数与物理参数的基线测量进行比较，以分析患者对CRT的反应，（f）在植入过程中调整CRT以尝试改善患者对CRT的反应，和 g）在植入过程期间重新定位至少一个患者导线，以试图改善患者对CRT的反应。

公开(公告)号：US07736198B2

公开(公告)日：2010-06-15

申请号：US11468910

申请日：2006-08-31

申请人： Vicki L. Bjorklund ,  John L. Sommer ,  Douglas S. Hine ,  Charles J. Love ,  Douglas N. Hess ,  Nicolaas M. Lokhoff

发明人： Vicki L. Bjorklund ,  John L. Sommer ,  Douglas S. Hine ,  Charles J. Love ,  Douglas N. Hess ,  Nicolaas M. Lokhoff

IPC分类号： H01R13/24

CPC分类号： A61N1/056 ,  A61N1/057 ,  A61N2001/058

摘要： An improved medical lead assembly and method of use is provided. The lead assembly includes a lead body, and a spring member positioned adjacent to the lead body. The spring member may be deployed a selectable amount to maintain the lead body in a fixed location within a patient's body. The spring member may be an expandable coil, a mesh structure that is similar to a stent, or any other similar device that may be positioned in a low-profile state during a lead implant procedure. After the lead is positioned at a target destination, the spring member may be deployed an amount that is selected based on the characteristics of the surrounding tissue, including vessel size. According to one aspect of the invention, the lead assembly may provide means for facilitating chronic lead extraction.

摘要翻译： 提供了一种改进的医疗引线组件和使用方法。 引线组件包括引线体和邻近引线体定位的弹簧部件。 弹簧构件可以部署可选择的量以将引线体保持在患者体内的固定位置。 弹簧构件可以是可扩张线圈，类似于支架的网状结构或者在引线植入过程期间可以被定位在低轮廓状态的任何其它类似的装置。 在引线定位在目标目的地之后，弹簧构件可以展开一定量，该量基于包括容器尺寸的周围组织的特性来选择。 根据本发明的一个方面，引线组件可以提供用于促进慢性铅提取的装置。

公开(公告)号：US06705900B2

公开(公告)日：2004-03-16

申请号：US09838814

申请日：2001-04-19

申请人： John L. Sommer ,  Douglas S. Hine ,  Vicki L. Bjorklund ,  Elisabeth Lacy Belden ,  William J. Clemens ,  Andrew J. Ries ,  Jordon D. Honeck ,  Harry Schroder

发明人： John L. Sommer ,  Douglas S. Hine ,  Vicki L. Bjorklund ,  Elisabeth Lacy Belden ,  William J. Clemens ,  Andrew J. Ries ,  Jordon D. Honeck ,  Harry Schroder

IPC分类号： H01R2404

CPC分类号： H01R31/06 ,  A61N1/3752 ,  H01R13/5224 ,  H01R2201/12

摘要： An improved connection system for coupling a device such as a pacemaker, cardioverter, defibrillator, nerve stimulator, muscle stimulator, implantable monitor or other medical device to a medical lead is disclosed. The connection system includes a coupling member designed to couple to the proximal end of the lead. This coupling member, which includes an inner lumen sized to form a press fit around the proximal end of the lead body, may be of a generally tubular construction. This coupling member includes connector means to enable a connector pin at the proximal end of the lead to mechanically and electrically couple to a device. The connector means may further include means for coupling both mechanically and electrically to a ring connector on the proximal end of a multi-polar lead. An insertion member may also be provided to allow the lead to be more easily inserted within the inner lumen of the coupling member.

摘要翻译： 公开了一种用于将诸如起搏器，心律转换器，除颤器，神经刺激器，肌肉刺激器，可植入监视器或其他医疗装置的装置耦合到医疗引线的改进的连接系统。 连接系统包括设计成耦合到引线的近端的耦合构件。 该联接构件包括尺寸适于形成围绕引线主体的近端的压配合的内腔，其可以是大致管状的结构。 该联接构件包括连接器装置，以使引线的近端处的连接器销能够机械地和电气地耦合到装置。 连接器装置还可以包括用于将机械和电耦合到多极引线的近端上的环形连接器的装置。 还可以设置插入构件以允许引线更容易地插入到联接构件的内腔内。

公开(公告)号：US06567704B2

公开(公告)日：2003-05-20

申请号：US09833518

申请日：2001-04-12

申请人： Steven Sundquist ,  Douglas S. Hine ,  John L. Sommer

发明人： Steven Sundquist ,  Douglas S. Hine ,  John L. Sommer

IPC分类号： A61N105

CPC分类号： A61N1/0568 ,  A61N1/057

摘要： A medical electrical lead is disclosed having an inner lumen adapted to receive a stiffening member, and which is further adapted to deliver fluoro-visible media while the stiffening member is located within the inner lumen. According to one aspect of the invention, the stiffening member is a guide wire having an inner lumen. The inner lumen of the guide wire is used to deliver the contrast medium while the guide wire is in place within the lumen of the lead. In another embodiment, a stiffening member that is sized to occupy only a portion of the lumen of the lead is utilized. The non-occupied portion of the lumen is sized to be large enough to allow for the passage of fluoro-visible medium from an injection port at the proximal end of the lead to a delivery port at the distal end of the lead. According to one aspect of the invention, the lead includes a sealable member located at the distal end of the lumen of the lead to prevent the ingress of bodily fluids within this lead lumen. The sealable member includes an opening to allow the stiffening member to be advanced outside of the lead lumen. In one embodiment, the sealable member is a flexible membrane including at least one opening to allow for passage of the stiffening member. In another embodiment, the sealable member includes multiple flap-like structures that seal around a stiffening member advanced distally of the lead body. In yet another embodiment, a sealable member is located within an electrode at the distal tip of the lead. The electrode of this configuration is provided with diametrically opposed openings to allow the electrode to expand to allow for passage of the stiffening member. The lead of the current invention may further include an inflatable member that may be inflated prior to delivery of the contrast media to prevent the media from being flushed from a vessel before a venogram is obtained.

公开(公告)号：US06192280B1

公开(公告)日：2001-02-20

申请号：US09324460

申请日：1999-06-02

申请人： John L. Sommer ,  Douglas S. Hine

发明人： John L. Sommer ,  Douglas S. Hine

IPC分类号： A61N105

CPC分类号： A61N1/0565

摘要： A guidewire placed lead employing a seal at its distal end in order to prevent entry of body fluid into the lead. The seal is particularly designed to allow radial expansion of the outer circumference of the seal due to passage of the guidewire through the seal, reducing the force required to pass the guidewire through the seal, while retaining a good sealing characteristics. The seal may extend a distance distally from the tip electrode, and include a hollow, resilient, cup-shaped seal member, configured so that the seal can readily expand radially as the guidewire passes through it. Alternatively, the seal may be located within the body of the electrode and the electrode configured so that it may be radially or laterally expanded, also allowing radial expansion of the seal during passage of the guidewire. In this case, the electrode may be rendered expandable by means of one or more slits arranged along the electrode body, extending from a point proximal to the guidewire seal.

摘要翻译： 引导线在其远端放置铅使用密封，以防止体液进入铅。 密封件特别设计成允许由于导丝通过密封件而使密封件的外周径向膨胀，从而减小了使导丝通过密封件所需的力，同时保持良好的密封特性。 密封件可以从尖端电极向远侧延伸一段距离，并且包括中空弹性的杯形密封件，其构造成使得当导丝穿过密封件时，密封件可以容易地径向膨胀。 或者，密封件可以位于电极的主体内，并且电极构造成使得其可以径向或横向膨胀，并且还允许密封件在导丝通过期间径向膨胀。 在这种情况下，电极可以通过沿着电极体布置的一个或多个狭缝来扩展，从靠近导丝密封的点延伸。

公开(公告)号：US08639340B2

公开(公告)日：2014-01-28

申请号：US10635166

申请日：2003-08-06

申请人： John L. Sommer ,  Douglas S. Hine ,  Douglas N. Hess

发明人： John L. Sommer ,  Douglas S. Hine ,  Douglas N. Hess

IPC分类号： A61N1/375

CPC分类号： A61N1/3752

摘要： A connector sleeve includes a lumen adapted to receive a medical lead connector wherein a retention element engages a retention edge formed at a distal end of a connector element included on the lead connector. The connector sleeve further includes a contact element adapted to electrically engage the lead connector element within the lumen and an external conductive surface electrically coupled to the contact element and adapted for electrical engagement within the connector bore of an implantable medical device.

摘要翻译： 连接器套管包括适于接收医疗引线连接器的内腔，其中保持元件接合形成在包括在引线连接器上的连接器元件的远端处的保持边缘。 连接器套筒还包括适于电连接腔内的引线连接器元件的接触元件和电耦合到接触元件的外部导电表面，并且适于电连接在可植入医疗器械的连接器孔内。