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公开(公告)号：US06283955B1
公开(公告)日：2001-09-04
申请号：US08648638
申请日：1996-05-13
IPC分类号： A61F700
CPC分类号： A61B18/24 , A61B2017/00181 , A61B2017/00247 , A61B2017/00703 , A61B2017/22074 , A61B2018/00392
摘要： A controlled advancement laser ablation device is provided for precise ablation of body matter. The laser ablation device includes a laser energy transmission mechanism such as, e.g. a fiber optic fiber mounted for controlled translational longitudinal movement relative to a housing structure. A laser energy generator is optically connected to the laser energy transmission mechanism. A controlled advancement mechanism is provided in engagement with the laser energy transmission mechanism for advancing the mechanism through the housing structure at a controlled rated coordinated with the laser energy generator output to ablate body tissue. Controlled advancement mechanisms include constant and/or variable rate springs, motors, and other mechanisms which can be coordinated with the laser energy generator to advance the laser energy transmission mechanism as the targeted substance is ablated. The device is particularly suitable for use in transmyocardial revascularization (TMR) and angioplasty procedures.
摘要翻译： 提供了一种用于精确消除身体物质的受控进步激光消融装置。 激光烧蚀装置包括例如激光能量传递机构。 安装成相对于壳体结构控制的平移纵向运动的光纤。 激光能量发生器与激光能量传递机构光学连接。 提供了一种与激光能量传递机构接合的受控进步机构，用于通过与激光能量发生器输出协调的受控额定值来推进机构通过壳体结构以烧蚀身体组织。 受控的前进机构包括恒定和/或可变速率弹簧，马达和其他机构，其可以与激光能量发生器配合，以在靶物质被消融时推进激光能量传递机制。 该装置特别适用于经心肌血运重建术（TMR）和血管成形术程序。
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公开(公告)号：US06280437B1
公开(公告)日：2001-08-28
申请号：US09653340
申请日：2000-08-31
IPC分类号： A61F700
CPC分类号： A61B18/24 , A61B2017/00181 , A61B2017/00247 , A61B2017/00703 , A61B2017/22074 , A61B2018/00392
摘要： A controlled advancement laser ablation device is provided for precise ablation of body matter. The laser ablation device includes a laser energy transmission mechanism such as, e.g., a fiber optic fiber mounted for controlled translational longitudinal movement relative to a housing structure. A laser energy generator is optically connected to the laser energy transmission mechanism. A controlled advancement mechanism is provided in engagement with the laser energy transmission mechanism for advancing the mechanism through the housing structure at a controlled rated coordinated with the laser energy generator output to ablate body tissue. Controlled advancement mechanisms include constant and/or variable rate springs, motors, and other mechanisms which can be coordinated with the laser energy generator to advance the laser energy transmission mechanism as the targeted substance is ablated. The device is particularly suitable for use in transmyocardial revascularization (TMR) and angioplasty procedures.
摘要翻译： 提供了一种用于精确消除身体物质的受控进步激光消融装置。 激光烧蚀装置包括激光能量传递机构，例如安装成相对于壳体结构控制的平移纵向移动的光纤纤维。 激光能量发生器与激光能量传递机构光学连接。 提供了一种与激光能量传递机构接合的受控进步机构，用于通过与激光能量发生器输出协调的受控额定值来推进机构通过壳体结构以烧蚀身体组织。 受控的前进机构包括恒定和/或可变速率弹簧，马达和其他机构，其可以与激光能量发生器配合，以在靶物质被消融时推进激光能量传递机制。 该装置特别适用于经心肌血运重建术（TMR）和血管成形术程序。
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公开(公告)号：US6135996A
公开(公告)日：2000-10-24
申请号：US62527
申请日：1998-04-17
CPC分类号： A61B18/22 , A61B2017/00973
摘要： A controlled advancement laser ablation device is provided for precise ablation of body matter. The laser ablation device includes a handle portion having proximal and distal openings and a fiber advancing device having a stationary member and a movable member. The movable member is movable towards and away from the stationary member. A fiber casing is included having proximal and distal ends. The distal end is secured to the proximal end of the handle portion and the proximal end is secured to the stationary member. At least one optical fiber is included having proximal and distal ends. The distal end is extendible through the handle portion and a portion of the fiber, defined between the proximal and distal ends, is secured to the movable member. A laser energy generator is optically connected to the proximal end of the optical fiber. The handle portion includes a self-biasing advancing mechanism. The self-biasing advancing mechanism includes a guide member positioned within at least a portion of a channel extending within the handle portion. At least one biasing member is operatively connected to the guide member to guide the guide member proximally as a proximal force is applied to the distal end of the optical fiber and to guide the guide member distally when laser energy is transmitted to the optical fiber by the laser energy generator. Controlled advancement mechanisms include constant and/or variable rate springs, motors, and other mechanisms which can be coordinated with the laser energy generator to advance the laser energy transmission mechanism as the targeted substance is ablated. The device is suitable for use in transmyocardial revascularization (TMR) and angioplasty procedures.
摘要翻译： 提供了一种用于精确消除身体物质的受控进步激光消融装置。 激光烧蚀装置包括具有近端和远端开口的把手部分和具有静止部件和可移动部件的纤维推进装置。 可移动构件可朝向和远离固定构件移动。 包括具有近端和远端的纤维套管。 远端固定到把手部分的近端并且近端固定到固定构件。 包括具有近端和远端的至少一根光纤。 远端可延伸通过手柄部分，并且限定在近端和远端之间的纤维的一部分固定到可动构件。 激光能量发生器光学连接到光纤的近端。 手柄部分包括自偏压推进机构。 自偏压推进机构包括定位在在手柄部分内延伸的通道的至少一部分内的引导构件。 至少一个偏置构件可操作地连接到引导构件，以在近侧力施加到光纤的远端时向近侧引导引导构件，并且当激光能量通过光纤被传送到光纤时将引导构件向远侧引导 激光能量发生器。 受控的前进机构包括恒定和/或可变速率弹簧，马达和其他机构，其可以与激光能量发生器配合，以在靶物质被消融时推进激光能量传递机制。 该装置适用于经心肌血运重建术（TMR）和血管成形术程序。
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公开(公告)号：US5980545A
公开(公告)日：1999-11-09
申请号：US650485
申请日：1996-05-13
申请人： Thomas J. Pacala , James Correia , Oleg Shikhman
发明人： Thomas J. Pacala , James Correia , Oleg Shikhman
CPC分类号： A61B17/32002 , A61B18/14 , A61B18/1482 , A61B10/02 , A61B17/32 , A61B17/320068 , A61B17/32053 , A61B17/3211 , A61B2017/00243 , A61B2017/00247 , A61B2018/00196 , A61B2018/00208 , A61B2018/00392 , A61B2018/0091 , A61B2018/00916 , A61B2018/126 , A61B2018/1861 , A61B2217/005 , A61B2217/007
摘要： A coring device for coring body tissue to define reproducible patent channels in the body tissue is provided. The coring device utilizes a coring member that is rotatable and linearly advanceable at coordinated predetermined rates to core body tissue. The device can include a suction assembly suitable for use during biopsy procedures and a cautery assembly to cauterize the cored body tissue. The coring member can also be oscillated along its longitudinal axis to effect cauterization and/or coring. The coring device is particularly suited for Transmyocardial Revascularization (TMR).
摘要翻译： 提供了用于取芯身体组织以确定身体组织中可再现的专利通道的取芯装置。 取芯装置利用可以以协调的预定速率旋转并线性前进到芯体组织的取芯构件。 该装置可以包括适于在活组织检查过程中使用的抽吸组件和用于烧结芯体组织的烧灼组件。 取芯构件也可以沿其纵向轴线振荡以实现烧灼和/或取芯。 取芯装置特别适用于经心肌血运重建术（TMR）。
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公开(公告)号：US5911729A
公开(公告)日：1999-06-15
申请号：US910713
申请日：1997-08-13
申请人： Oleg Shikhman , James Correia , Thomas J. Pacala
发明人： Oleg Shikhman , James Correia , Thomas J. Pacala
CPC分类号： A61B18/1402 , A61B18/14 , A61B2017/00247 , A61B2018/00392 , A61B2018/0091
摘要： The present disclosure relates to a method apparatus for transmyocardial revascularization. The apparatus includes an incision needle for creating an incision within a patient's heart to define a channel, and an electrocautery assembly operatively associated with the incision needle for transferring thermal energy to an inner surface of the channel to reduce bleeding therefrom and to prevent the channel from closing. Preferably, thermal energy is not transferred to the epicardium to create a flap or channel cap after the cylindrical incision needle is removed from relevant tissue to reduce bleeding from the channel.
摘要翻译： 本公开涉及一种用于经心肌血运重建的方法装置。 该装置包括用于在患者心脏内创建切口以限定通道的切口针，以及与切口针可操作地相关联的电烙术组件，用于将热能传递到通道的内表面以减少从其中渗出并防止通道 关闭。 优选地，在将圆柱形切口针从相关组织移除以减少从通道出血之后，热能不转移到心外膜以产生瓣或通道帽。
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公开(公告)号：US5807383A
公开(公告)日：1998-09-15
申请号：US720934
申请日：1996-10-04
CPC分类号： A61B18/24 , A61B2017/00181 , A61B2017/00247 , A61B2017/00703 , A61B2017/22074 , A61B2018/00392
摘要： A controlled advancement laser ablation device is provided for precise ablation of body matter. The laser ablation device includes a laser energy transmission mechanism such as, e.g. a fiber optic fiber mounted for controlled translational longitudinal movement relative to a housing structure. A laser energy generator is optically connected to the laser energy transmission mechanism. A controlled advancement mechanism is provided in engagement with the laser energy transmission mechanism for advancing the mechanism through the housing structure at a controlled rated coordinated with the laser energy generator output to ablate body tissue. Controlled advancement mechanisms include constant and/or variable rate springs, motors, and other mechanisms which can be coordinated with the laser energy generator to advance the laser energy transmission mechanism as the targeted substance is ablated. The device is particularly suitable for use in transmyocardial revascularization (TMR) and angioplasty procedures.
摘要翻译： 提供了一种用于精确消除身体物质的受控进步激光消融装置。 激光烧蚀装置包括例如激光能量传递机构。 安装成相对于壳体结构控制的平移纵向运动的光纤。 激光能量发生器与激光能量传递机构光学连接。 提供了一种与激光能量传递机构接合的受控进步机构，用于通过与激光能量发生器输出协调的受控额定值来推进机构通过壳体结构以烧蚀身体组织。 受控的前进机构包括恒定和/或可变速率弹簧，马达和其他机构，其可以与激光能量发生器配合，以在靶物质被消融时推进激光能量传递机制。 该装置特别适用于经心肌血运重建术（TMR）和血管成形术程序。
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公开(公告)号：US5947989A
公开(公告)日：1999-09-07
申请号：US764417
申请日：1996-12-12
申请人： Oleg Shikhman , James Correia
发明人： Oleg Shikhman , James Correia
CPC分类号： A61B18/24 , A61B17/32053 , A61B2017/00247 , A61B2018/00392
摘要： A method for performing transmyocardial revascularization (TMR) comprises the steps of creating an incision in an outer portion of heart tissue of a patient and creating a channel in the patient's myocardium through the incision by advancing a channel creating device into the myocardium beyond the depth of the incision to remove myocardial tissue without removing all outer portion heart tissue coinciding with the channel. As a result, the remaining outer portion tissue acts as a cap to reduce bleeding from the channel subsequent to removal of the channel creating device. The cap may be in the form of an annular flap of myocardial/epicardial tissue. The channel creating device used to create the channel with the method can be either a mechanical coring device or an advancing lasing device.
摘要翻译： 一种执行经心肌血运重建（TMR）的方法包括以下步骤：在患者的心脏组织的外部部分中产生切口，并且通过将切口形成通道，使得通道产生装置进入心肌超过深度 切除去除心肌组织而不去除与通道重合的所有外部部分心脏组织。 结果，剩余的外部组织用作帽，以在去除通道产生装置之后减少从通道的渗出。 帽可以是心肌/心外膜组织的环形瓣的形式。 用于通过该方法创建通道的通道创建装置可以是机械取芯装置或推进的激光装置。
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公开(公告)号：US06350227B1
公开(公告)日：2002-02-26
申请号：US09509253
申请日：2000-06-12
IPC分类号： A61N500
CPC分类号： A61N5/1007 , A61N2005/1008
摘要： There is provided a manually operable afterloader (100) for use during radiation therapy treatment of a patient. The afterloader (100) includes a sourcewire reel (112) having a circumferential groove, dual sized or stepped (188), for receipt of a non-radioactive portion of a sourcewire (130) and a shield capsule (154) having a passageway therethrough for receipt of a radioactive portion of a source wire (130). A cranking mechanism (163) is provided to rotate the sourcewire reel (112) and drive the radioactive sourcewire (130) out of the shield capsule (154).
摘要翻译： 提供了一种可手动操作的后加载器（100），用于在患者的放射治疗期间使用。 后加载器（100）包括源线卷轴（112），其具有双重尺寸或台阶（188）的周向凹槽，用于接收源线（130）的非放射性部分和具有穿过其中的通道的屏蔽胶囊（154） 用于接收源极线（130）的放射性部分。 提供起动机构（163）以旋转源线卷轴（112）并将放射源线（130）驱动出屏蔽胶囊（154）。
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公开(公告)号：US11097062B2
公开(公告)日：2021-08-24
申请号：US16728212
申请日：2019-12-27
申请人： Gennady Kleyman , Alexander Merson , Oleg Shikhman
发明人： Gennady Kleyman , Alexander Merson , Oleg Shikhman
摘要： A fluid dispensing device having a barrel having a lumen for containing a fluid therein and a flexible structure extending from the barrel. A plunger is axially slidable within the lumen to dispense fluid from the barrel, the plunger having a first set of grooves spaced apart a first distance and a second set of grooves spaced apart a second distance. The flexible structure includes a flexible arm extending transversely with respect to the barrel and configured to engage the grooves.
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公开(公告)号：US09833250B2
公开(公告)日：2017-12-05
申请号：US13716184
申请日：2012-12-16
申请人： Gregory Piskun , Patrick Gutelius , Oleg Shikhman
发明人： Gregory Piskun , Patrick Gutelius , Oleg Shikhman
IPC分类号： A61B17/3205 , A61B17/22 , A61B17/34 , A61B1/06 , A61B17/122 , A61B17/128 , A61B90/30 , A61B17/02 , A61B17/12 , A61B18/18 , A61B18/14 , A61B18/00 , A61B90/00
CPC分类号： A61B17/22031 , A61B1/06 , A61B17/02 , A61B17/12013 , A61B17/122 , A61B17/1285 , A61B17/3205 , A61B17/3421 , A61B18/1485 , A61B18/18 , A61B90/30 , A61B2017/3452 , A61B2018/005 , A61B2090/032
摘要： An apparatus for treating hemorrhoids including a first member having a proximal portion, a distal portion and a window formed therein to receive tissue. A third member is operably connected to the second member and movable between a first position and a second position, the third member having a clamping surface movable to the second position to provide a clamping force on tissue received through the window. Movement of the second member in a distal direction moves the third member in the distal direction toward the second position, the third member movable in a distal direction until such movement is limited due to contact and compression of tissue within the window, the second member continuing movement in the distal direction after movement of the third member in the distal direction has been limited.
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