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1.发明授权公开(公告)号：US07632679B2
公开(公告)日：2009-12-15
申请号：US10789308
申请日：2004-02-26
申请人： Thomas Jessell , Hynek Wichterle , Sara Wilson
发明人： Thomas Jessell , Hynek Wichterle , Sara Wilson
CPC分类号： C12N5/0619 , A61K35/12 , C12N5/0623 , C12N2501/155 , C12N2501/385 , C12N2501/41 , C12N2501/415 , C12N2503/00 , C12N2503/02 , C12N2506/02 , G01N33/5073 , G01N2333/51 , Y02A50/465
摘要： The present invention provides in vitro systems for use in identifying modulators of neural differentiation. Also provided are modulators identified by these systems. The present invention further provides methods for identifying a modulator of neural differentiation, a modulator of a Wnt signalling pathway, a modulator of Wnt-dependent neural differentiation, a modulator of a BMP signalling pathway, a modulator of BMP-dependent neural differentiation, a modulator of a Hh signalling pathway, and a modulator of Hh-dependent neural differentiation. Also provided are modulators identified by these methods.
摘要翻译： 本发明提供用于鉴定神经分化调节剂的体外系统。 还提供了由这些系统识别的调制器。 本发明还提供用于鉴定神经分化调节剂，Wnt信号通路调节剂，Wnt依赖性神经分化调节剂，BMP信号通路调节剂，BMP依赖性神经分化调节剂，调节剂 的Hh信号通路，以及Hh依赖性神经分化的调节剂。 还提供了通过这些方法鉴定的调节剂。
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2.发明申请公开(公告)号：US20070224650A1
公开(公告)日：2007-09-27
申请号：US11510366
申请日：2006-08-25
申请人： Thomas Jessell , Hynek Wichterle , Sara Wilson , Ivo Lieberam
发明人： Thomas Jessell , Hynek Wichterle , Sara Wilson , Ivo Lieberam
IPC分类号： G01N33/567 , C12N5/06 , C12N5/08
CPC分类号： C12N5/0619 , A61K35/12 , A61K35/545 , C12N2501/155 , C12N2501/385 , C12N2501/41 , C12N2501/415 , C12N2502/13 , C12N2506/02 , G01N33/5073 , G01N33/74 , G01N2333/475 , G01N2333/51
摘要： The present invention provides in vitro systems for use in identifying modulators of neural differentiation. Also provided are modulators identified by these systems. The present invention further provides methods for identifying a modulator of neural differentiation, a modulator of an FGF signalling pathway, a modulator of FGF-dependent neural differentiation, a modulator of a retinoid signalling pathway, and a modulator of retinoid-dependent neural differentiation. Also provided are modulators identified by these methods.
摘要翻译： 本发明提供用于鉴定神经分化调节剂的体外系统。 还提供了由这些系统识别的调制器。 本发明还提供用于鉴定神经分化调节剂，FGF信号通路调节剂，FGF依赖性神经分化调节剂，类视黄醇信号通路调节剂和类视黄醇依赖性神经分化调节剂的方法。 还提供了通过这些方法鉴定的调节剂。
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3.发明申请公开(公告)号：US20070185024A1
公开(公告)日：2007-08-09
申请号：US11510038
申请日：2006-08-25
申请人： Thomas Jessell , Hynek Wichterle , Sara Wilson , Ivo Lieberam
发明人： Thomas Jessell , Hynek Wichterle , Sara Wilson , Ivo Lieberam
IPC分类号： A61K38/17 , G01N33/567 , C12N5/08 , A61K31/203 , A61K31/07
CPC分类号： C12N5/0619 , A61K35/12 , C12N5/0623 , C12N2501/155 , C12N2501/385 , C12N2501/41 , C12N2501/415 , C12N2503/00 , C12N2503/02 , C12N2506/02 , G01N33/5073 , G01N2333/51 , Y02A50/465
摘要： The present invention provides in vitro systems for use in identifying modulators of neural differentiation. Also provided are modulators identified by these systems. The present invention further provides methods for identifying a modulator of neural differentiation, a modulator of a Wnt signalling pathway, a modulator of Wnt-dependent neural differentiation, a modulator of a BMP signalling pathway, a modulator of BMP-dependent neural differentiation, a modulator of a Hh signalling pathway, and a modulator of Hh-dependent neural differentiation. Also provided are modulators identified by these methods.
摘要翻译： 本发明提供用于鉴定神经分化调节剂的体外系统。 还提供了由这些系统识别的调制器。 本发明还提供用于鉴定神经分化调节剂，Wnt信号通路调节剂，Wnt依赖性神经分化调节剂，BMP信号通路调节剂，BMP依赖性神经分化调节剂，调节剂 的Hh信号通路，以及Hh依赖性神经分化的调节剂。 还提供了通过这些方法鉴定的调节剂。
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公开(公告)号：USD632048S1
公开(公告)日：2011-02-08
申请号：US29352755
申请日：2009-12-24
申请人： Warren Wilson , Sara Wilson
设计人： Warren Wilson , Sara Wilson
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公开(公告)号：US20190295163A1
公开(公告)日：2019-09-26
申请号：US16364574
申请日：2019-03-26
申请人： John Zurick , Lee Latimer , Matt Mantia , Mike Foulk , Sara Wilson , Erica Delaney
发明人： John Zurick , Lee Latimer , Matt Mantia , Mike Foulk , Sara Wilson , Erica Delaney
摘要： A system and method for assisting loan borrowers in assessing possible repayment options includes collecting borrower information and classifying borrowers according to campaign groups. Borrowers in each campaign group are contacted in a manner specifically designed for that campaign group to optimize the likelihood of generating a response from the borrower. A chatbot is used to generate a text or voice conversation with the borrower utilizing simple and short questions and answers to obtain information from the borrower and determine the borrower's eligibility for different repayment options. The chatbot then provides the borrower with a list of options which the borrower may select from. The system and method also includes providing a complete transcripts of the conversation to the borrower.
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公开(公告)号：USD648096S1
公开(公告)日：2011-11-08
申请号：US29383782
申请日：2011-01-21
申请人： Warren Wilson , Sara Wilson
设计人： Warren Wilson , Sara Wilson
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公开(公告)号：USD648506S1
公开(公告)日：2011-11-15
申请号：US29383787
申请日：2011-01-21
申请人： Warren Wilson , Sara Wilson
设计人： Warren Wilson , Sara Wilson
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公开(公告)号：USD670066S1
公开(公告)日：2012-11-06
申请号：US29383795
申请日：2011-01-21
申请人： Warren Wilson , Sara Wilson
设计人： Warren Wilson , Sara Wilson
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公开(公告)号：USD648097S1
公开(公告)日：2011-11-08
申请号：US29383793
申请日：2011-01-21
申请人： Warren Wilson , Sara Wilson
设计人： Warren Wilson , Sara Wilson
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公开(公告)号：USD515277S1
公开(公告)日：2006-02-21
申请号：US29214634
申请日：2004-10-07
申请人： Sara Wilson , Warren Wilson
设计人： Sara Wilson , Warren Wilson
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