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    Responsive Electrical Stimulation for Movement Disorders
    1.
    发明申请
    Responsive Electrical Stimulation for Movement Disorders 有权
    运动障碍的反应性电刺激

    公开(公告)号：US20110004268A1

    公开(公告)日：2011-01-06

    申请号：US12881143

    申请日：2010-09-13

    申请人： Thomas K. Tcheng ,  Robert E. Fischell ,  Benjamin D. Pless

    发明人： Thomas K. Tcheng ,  Robert E. Fischell ,  Benjamin D. Pless

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36067 ,  A61N1/36135

    摘要： An implantable neurostimulator system for treating movement disorders includes a sensor, a detection subsystem capable of identifying episodes of a movement disorder by analyzing a signal received from the sensor, and a therapy subsystem capable of supplying therapeutic electrical stimulation to treat the movement disorder. The system treats movement disorders by detecting physiological conditions characteristic of an episode of symptoms of the movement disorder and selectively initiating therapy when such conditions are detected.

    摘要翻译： 用于治疗运动障碍的可植入神经刺激器系统包括传感器，能够通过分析从传感器接收的信号来识别运动障碍发作的检测子系统，以及能够提供治疗性电刺激以治疗运动障碍的治疗子系统。 该系统通过检测运动障碍症状发作特征的生理条件来治疗运动障碍，并且当检测到这种病症时选择性地开始治疗。

    Responsive electrical stimulation for movement disorders
    4.
    发明授权
    Responsive electrical stimulation for movement disorders 有权
    反应性电刺激运动障碍

    公开(公告)号：US07813802B2

    公开(公告)日：2010-10-12

    申请号：US11517783

    申请日：2006-09-08

    申请人： Thomas K. Tcheng ,  Robert E. Fischell ,  Benjamin D. Pless

    发明人： Thomas K. Tcheng ,  Robert E. Fischell ,  Benjamin D. Pless

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36067 ,  A61N1/36135

    摘要： An implantable neurostimulator system for treating movement disorders includes a sensor, a detection subsystem capable of identifying episodes of a movement disorder by analyzing a signal received from the sensor, and a therapy subsystem capable of applying therapeutic electrical stimulation to treat the movement disorder. The system treats movement disorders by detecting physiological conditions characteristic of an episode of symptoms of the movement disorder and selectively initiating therapy when such conditions are detected.

    摘要翻译： 用于治疗运动障碍的可植入神经刺激器系统包括传感器，能够通过分析从传感器接收的信号来识别运动障碍的发作的检测子系统，以及能够施加治疗性电刺激以治疗运动障碍的治疗子系统。 该系统通过检测运动障碍症状发作特征的生理条件来治疗运动障碍，并且当检测到这种病症时选择性地开始治疗。

    Means and method for the intracranial placement of a neurostimulator
    5.
    发明授权
    Means and method for the intracranial placement of a neurostimulator 有权
    用于颅内放置神经刺激器的方法和方法

    公开(公告)号：US06427086B1

    公开(公告)日：2002-07-30

    申请号：US09557168

    申请日：2000-04-21

    申请人： Robert E. Fischell ,  David R. Fischell ,  Adrian R. M. Upton ,  Dennis R. Potts ,  Benjamin D. Pless

    发明人： Robert E. Fischell ,  David R. Fischell ,  Adrian R. M. Upton ,  Dennis R. Potts ,  Benjamin D. Pless

    IPC分类号： A61N136

    CPC分类号： A61B5/6814 ,  A61B5/0476 ,  A61B5/4094 ,  A61N1/36017 ,  A61N1/36025 ,  A61N1/3605 ,  A61N1/36064 ,  A61N1/37235

    摘要： Disclosed is a means and method for placing an implantable neurostimulator control module into a place in the cranium where cranial bone has been removed. The method for accomplishing this cranial implantation is by first removing a patient's hair over the site of the implant, then cutting the scalp at that site and pulling it back to expose the cranium. A neurosurgeon would then remove a portion of the cranial bone to accept a control module to be implanted within that hole. The control module would then be placed into that hole. It is also conceived that the control module would be fixed in place by the use of one or more attachment devices such as a multiplicity of bone screws placed through holes in one or more flanges that extend over the cranium beyond the control module. The implantation could also include a fairing placed around the control module to provide a smooth contour under the patient's scalp. Also described is a spacer shim placed under the flange(s) to adjust the position of the control module so that its bottom surface does not put pressure on the dura mater lying directly over the brain tissue at the bottom of the hole. It is also envisioned that a resorbable disk could be placed under the bottom surface of the control module to further protect the brain and/or to elute an anti-biotic or anti-inflammatory substance to reduce the possibility of infection and/or inflammation.

    摘要翻译： 公开了一种用于将可植入的神经刺激器控制模块放置在颅骨已被移除的头颅中的位置的手段和方法。 完成这种颅骨植入的方法是首先将患者的头发去除植入物的部位，然后在该部位切割头皮并将其拉回以暴露颅骨。 然后，神经外科医生将去除颅骨的一部分以接受待植入该孔内的控制模块。 然后将控制模块放入该孔中。 还可以想到，控制模块将通过使用一个或多个附接装置固定在适当的位置，例如通过一个或多个凸缘中的孔布置的多个骨螺钉，所述多个骨螺钉在颅骨上延伸超过控制模块。 植入还可以包括放置在控制模块周围的整流罩，以在患者的头皮下面提供平滑的轮廓。 还描述了放置在凸缘下方的间隔垫片，以调节控制模块的位置，使得其底部表面不对直接位于孔底部的脑组织的硬脑膜施加压力。 还可以设想，可再吸收的盘可以放置在控制模块的底表面下方以进一步保护大脑和/或洗脱抗生素或抗炎物质以减少感染和/或炎症的可能性。

    Nasal strip having improved characteristics
    7.
    发明授权
    Nasal strip having improved characteristics 有权
    具有改善特征的鼻带

    公开(公告)号：US09204988B1

    公开(公告)日：2015-12-08

    申请号：US14468881

    申请日：2014-08-26

    申请人： Robert E. Fischell

    发明人： Robert E. Fischell

    IPC分类号： A61F5/08

    CPC分类号： A61F5/08

    摘要： A nasal strip having a non-adhesive central portion situated between two adhesive end sections of the nasal strip. In one example, a thin plastic covering over the adhesive surface of the central portion of the nasal strip provides advantages of more torque obtained to open the nasal passageways, less discomfort on removal of the nasal strip, easier placement of the nasal strip onto the nose and less area of the skin on the nose that can be irritated by the adhesive interior surface of the nasal strip.

    摘要翻译： 鼻带，其具有位于鼻带的两个粘合剂端部之间的非粘性中心部分。 在一个示例中，覆盖在鼻带中心部分的粘合剂表面上的薄塑料提供了获得打开鼻通道的更多扭矩的优点，在去除鼻带时较少的不适，更容易将鼻带放置在鼻子上 并且鼻部皮肤的面积可以被鼻带的粘合剂内表面刺激。

    Cardiac event categorization system
    9.
    发明授权
    Cardiac event categorization system 有权
    心脏事件分类系统

    公开(公告)号：US08483812B2

    公开(公告)日：2013-07-09

    申请号：US12059146

    申请日：2008-03-31

    申请人： Robert E. Fischell ,  David R. Fischell ,  Tim A. Fischell ,  Scott J. S. Fischell

    发明人： Robert E. Fischell ,  David R. Fischell ,  Tim A. Fischell ,  Scott J. S. Fischell

    IPC分类号： A61B5/02 ,  A61N1/365

    CPC分类号： A61L27/54 ,  A61L2300/236 ,  A61L2300/254 ,  A61L2300/42

    摘要： Disclosed are methods for detecting an acute myocardial infarction (i.e., a heart attack) at the earliest possible time and promptly warning the patient that he should immediately seek medical care. The present invention includes an implantable electronic system that can sense a change in the patient's electrogram that is indicative of a heart attack. If a heart attack is sensed, the device would then cause an implantable and/or externally located alarm to be actuated to warn the patient of his condition and a medical practitioner at a remote diagnostic center would receive the patient's electrogram for analysis. The patient or a caretaker would then be informed to self-inject medication through a subcutaneous, pass-through drug port that can be a separate device or integrated into the implanted device that is designed for the early detection of a heart attack. The methods of the present invention include determining if a human patient is likely to have a heart attack and, if he is, then implanting within that patient a device that can sense when a heart attack occurs and alarm the patient to take appropriate actions if a heart attack does occur.

    摘要翻译： 公开了在早期检测急性心肌梗塞（即心脏病发作）的方法，并且及时警告患者他应该立即求医。 本发明包括可以感测指示心脏病发作的患者电描记图变化的可植入电子系统。 如果感测到心脏病发作，则该装置然后将致动可植入和/或外部定位的警报器，以警告患者其状况，并且远程诊断中心的医务人员将接收患者的电描记图以进行分析。 然后将患者或看守者通知皮下，通过的药物口，自动注射药物，该药物口可以是单独的装置，也可以集成到设计用于早期发现心脏病发作的植入装置中。 本发明的方法包括确定人类患者是否可能患有心脏病发作，并且如果他是，则在患者体内植入可以感测发生心脏病发作的装置，并且如果 心脏病发作确实发生。