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公开(公告)号：US5491067A
公开(公告)日：1996-02-13
申请号：US93106
申请日：1993-07-16
IPC分类号： B01L3/14 , G01N33/53 , G01N33/536 , G01N33/537 , G01N33/538 , G01N33/558
CPC分类号： B01L3/5021 , G01N33/5304 , Y10S436/805 , Y10S436/809 , Y10S436/81 , Y10S436/824
摘要： A vessel for conducting blood cell agglutination assays is disclosed. A barrier retains reactants in an upper chamber during incubation, then, in response to a force, permits reagents to enter a lower chamber containing a matrix for separating agglutination.
摘要翻译： 公开了用于进行血细胞凝集测定的血管。 屏障在孵育期间在上室中保留反应物，然后响应于力，允许试剂进入含有用于分离凝集的基质的下室。
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公开(公告)号：US5780248A
公开(公告)日：1998-07-14
申请号：US595719
申请日：1996-02-02
申请人： Walter Milchanoski , Milan Jorik , Kathleen J. Reis , Diane E. Bechtold , Linda Davis , Thomas M. Setcavage , Donald M. Davies
发明人： Walter Milchanoski , Milan Jorik , Kathleen J. Reis , Diane E. Bechtold , Linda Davis , Thomas M. Setcavage , Donald M. Davies
IPC分类号： B01L3/14 , G01N33/53 , G01N35/04 , G01N33/50 , G01N33/558
CPC分类号： G01N33/5304 , B01L3/5021 , G01N35/026 , Y10S435/805 , Y10S435/809 , Y10S435/81 , Y10S435/824 , Y10S436/809 , Y10S436/81
摘要： A vessel for conducting blood cell agglutination assays is disclosed. A barrier retains reactants in an upper chamber during incubation, then, in response to a force, permits reagents to enter a lower chamber containing a matrix for separating agglutination.
摘要翻译： 公开了用于进行血细胞凝集测定的血管。 屏障在孵育期间在上室中保留反应物，然后响应于力，允许试剂进入含有用于分离凝集的基质的下室。
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公开(公告)号：US5650068A
公开(公告)日：1997-07-22
申请号：US632974
申请日：1996-04-16
CPC分类号： B01L3/5021 , B01L3/508 , G01N33/491 , G01N33/5304 , G01N33/80 , B01L2300/0809 , B01L2300/0858 , B01L2400/0409 , B01L3/5082 , Y10T436/25375 , Y10T436/255
摘要： The present invention provides a method and device for detecting the presence of binding ligands, especially blood group antigens or antibodies thereto, which utilize a matrix of substantially noncompressable microparticles, which matrix provides superior performance in allowing movement of nonagglutinated reactants, especially red blood cells, while constraining, preferably in a so-called "band formation" agglutinated reactants, especially red blood cells. The device of the invention further comprises a chamber the transverse cross-sectional shape thereof being an ellipse, or preferably a flattened ellipse with two sides parallel to the longitudinal axis.
摘要翻译： 本发明提供一种用于检测结合配体，特别是血型抗原或其抗体的存在的方法和装置，其利用基本上不可压缩的微粒的基质，该基质在允许非凝集反应物，特别是红血细胞的运动中提供优异的性能， 同时约束，优选地在所谓的“带形成”凝集的反应物，特别是红细胞中。 本发明的装置还包括其横截面形状为椭圆形的腔室，或优选地具有平行于纵向轴线的两侧的扁平椭圆形。
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公开(公告)号：US5552064A
公开(公告)日：1996-09-03
申请号：US112402
申请日：1993-08-26
CPC分类号： B01L3/5021 , B01L3/508 , G01N33/491 , G01N33/5304 , G01N33/80 , B01L2300/0809 , B01L2300/0858 , B01L2400/0409 , B01L3/5082 , Y10T436/25375 , Y10T436/255
摘要： The present invention provides a method and device for detecting the presence of binding ligands, especially blood group antigens or antibodies thereto, which utilize a matrix of substantially noncompressable microparticles, which matrix provides superior performance in allowing movement of nonagglutinated reactants, especially red blood cells, while constraining, preferably in a so-called "band formation" agglutinated reactants, especially red blood cells.
摘要翻译： 本发明提供一种用于检测结合配体，特别是血型抗原或其抗体的存在的方法和装置，其利用基本上不可压缩的微粒的基质，该基质在允许非凝集反应物，特别是红血细胞的运动中提供优异的性能， 同时约束，优选地在所谓的“带形成”凝集的反应物，特别是红细胞中。
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公开(公告)号：US06187583B1
公开(公告)日：2001-02-13
申请号：US09086180
申请日：1998-05-28
申请人： Walter Milchanoski , Milan Jorik , Kathleen J. Reis , Diane E. Bechtold , Linda Davis , Thomas M. Setcavage
发明人： Walter Milchanoski , Milan Jorik , Kathleen J. Reis , Diane E. Bechtold , Linda Davis , Thomas M. Setcavage
IPC分类号： G01N33558
CPC分类号： G01N33/5304 , B01L3/5021 , G01N35/026 , Y10S435/805 , Y10S435/809 , Y10S435/81 , Y10S435/824 , Y10S436/809 , Y10S436/81
摘要： A vessel for conducting blood cell agglutination assays is disclosed. A barrier retains reactants in an upper chamber during incubation, then, in response to a force, permits reagents to enter a lower chamber containing a matrix for separating agglutination.
摘要翻译： 公开了用于进行血细胞凝集测定的血管。 屏障在孵育期间在上室中保留反应物，然后响应于力，允许试剂进入含有用于分离凝集的基质的下室。
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