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公开(公告)号：US07187980B2
公开(公告)日：2007-03-06
申请号：US10282203
申请日：2002-10-28
IPC分类号： A61N1/00
CPC分类号： A61N1/057 , A61N1/0568 , A61N1/0575
摘要： A cardiac lead is disclosed which includes an elongated lead body having opposed proximal and distal ends, a tip electrode operatively associated with the distal end of the elongated lead body, a connector operatively associated with the proximal end of the elongated lead body and electrically connected to the tip electrode, and a cylindrical eluting ring disposed proximate the tip electrode and formed from a compound including an elastomer and about 15% to 25% by weight medicament.
摘要翻译： 公开了一种心脏引线，其包括具有相对的近端和远端的细长引线体，与细长引线主体的远端可操作地相关联的尖端电极，可操作地与细长引线体的近端相连并且电连接到 末端电极和圆柱形洗脱环，其设置在尖端电极附近并由包含弹性体和约15重量％至25重量％的药物的化合物形成。
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公开(公告)号：US06671562B2
公开(公告)日：2003-12-30
申请号：US10281744
申请日：2002-10-28
IPC分类号： A61N100
CPC分类号： A61N1/057 , A61N1/0568 , A61N1/0575
摘要： A high impedance bipolar cardiac lead is disclosed that includes a lead body with a distal electrode assembly that includes an anodic ring electrode and a coaxially disposed cathodic tip electrode, wherein the anodic ring electrode and the cathodic tip electrode are separated from one another by a drug eluting insulating member.
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公开(公告)号：US09061120B2
公开(公告)日：2015-06-23
申请号：US12603584
申请日：2009-10-21
CPC分类号： A61M25/0147 , A61B5/0422 , A61M25/0136 , A61M25/0141
摘要： A steerable multi-polar lead shaft assembly includes a core member extending longitudinally through the shaft assembly, a plurality electrically conductive elements disposed within the core member, a plurality of steering wires circumferentially distributed about the core member. A control mechanism for a steerable catheter, such as the steerable multi-polar lead assembly, includes a mounting portion adapted to engage a steerable shaft, a stem extending from the mounting portion, a swivel joint arranged at a proximal end of the stem, a control yoke rotatably mounted on the swivel joint, adapted to engage a plurality of steering wires of the steerable catheter, and a handle connected with the yoke, adapted for direct manipulation by a user.
摘要翻译： 可操纵的多极引导轴组件包括纵向延伸穿过轴组件的芯构件，设置在芯构件内的多个导电元件，围绕芯构件周向分布的多个操纵线。 用于可转向导管（例如可转向多极引线组件）的控制机构包括适于接合可转向轴的安装部分，从安装部分延伸的杆，设置在杆的近端的旋转接头， 控制轭可旋转地安装在旋转接头上，适于接合可转向导管的多个操纵线，以及与轭相连接的手柄，适于用户直接操纵。
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4.发明授权公开(公告)号：US08150536B2
公开(公告)日：2012-04-03
申请号：US11811376
申请日：2007-06-08
申请人： Thomas P. Osypka
发明人： Thomas P. Osypka
IPC分类号： A61N1/05
CPC分类号： A61N1/0573
摘要： An active fixation cardiac lead is disclosed that includes an elongated lead body having opposed proximal and distal end portions and an interior lumen that extends therethrough. A rotatable fixation element is operatively associated with the distal end portion of the lead body and a tubular torque-transmitting member extends through the interior lumen of the lead body. The tubular torque-transmitting member has a distal end connected to the fixation element and a proximal end connected to a rotatable actuator operatively associated with the proximal end portion of the lead body. Preferably, the rotatable actuator is part of a connector assembly that is operatively associated with the proximal end portion of the lead body.
摘要翻译： 公开了一种主动定位心脏引线，其包括具有相对的近端部分和远端部分的细长引线体以及从其延伸穿过的内部腔体。 可旋转的固定元件与引线体的远端部分可操作地相关联，并且管状的扭矩传递部件延伸穿过引线体的内腔。 管状扭矩传递构件具有连接到固定元件的远端和连接到可操作地与引线主体的近端部分相关联的可旋转致动器的近端。 优选地，可旋转致动器是与引线主体的近端部分可操作地相关联的连接器组件的一部分。
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公开(公告)号：US08116875B2
公开(公告)日：2012-02-14
申请号：US11818728
申请日：2007-06-15
申请人： Thomas P. Osypka , Hyoung-Ihl Kim , Yong-Il Shin
发明人： Thomas P. Osypka , Hyoung-Ihl Kim , Yong-Il Shin
IPC分类号： A61N1/05
CPC分类号： A61N1/0531 , A61N1/0539
摘要： New and useful neurostimulation systems are provided that include an implantable pulse generator dimensioned and configured for implantation in the skull of a patient. The implantable pulse generator has an electrode operatively associated with a distal end portion thereof and can be provided with adjustment means, such as an adjustable biasing member or spring arranged between the electrode to the distal end portion of the pulse generator. Also provided are systems involving networked neurostimulators that are configured and adapted to work jointly in accordance with prescribed treatment protocol to effect a desired recovery from brain injury. Such networked neurostimulation systems are particularly advantageous for effecting relatively large and/or relatively distant regions of the brain. Additionally, systems and methods for motor-evoked potential (MEP)-based neuromodulation are provided. Further, AC and/or DC stimulation can be utilized, depending on the precise implementation.
摘要翻译： 提供了新的和有用的神经刺激系统，其包括可植入脉冲发生器，其尺寸和构造用于植入患者的头骨中。 可植入脉冲发生器具有与其远端部分可操作地相关联的电极，并且可以设置有调节装置，例如布置在电极与脉冲发生器的远端部分之间的可调偏压部件或弹簧。 还提供了涉及网络神经刺激器的系统，其被配置和适应于根据规定的治疗方案共同工作以实现从脑损伤的期望恢复。 这种联网神经刺激系统对于实现大脑相对较大和/或相对较远的区域特别有利。 此外，提供了基于运动诱发电位（MEP）的神经调节的系统和方法。 此外，根据精确实现，可以利用AC和/或DC刺激。
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6.发明授权公开(公告)号：US07904161B2
公开(公告)日：2011-03-08
申请号：US11179304
申请日：2005-07-12
申请人： Thomas P. Osypka
发明人： Thomas P. Osypka
IPC分类号： A61N1/00
CPC分类号： H01R31/06 , A61N1/056 , H01R24/58 , H01R27/02 , H01R31/02 , H01R2107/00 , H01R2201/12
摘要： An implantable lead adaptor is disclosed that includes an encapsulated thermoplastic housing defining a proximal end portion and a distal end portion. The proximal end portion has a first receptacle configured to receive a first type of connector assembly associated with a first implantable cardiac lead, and a second receptacle configured to receive a second type of connector assembly associated with a second implantable cardiac lead. An elongated flexible lead portion extends from the distal end portion of the adaptor housing. A connector assembly is operatively associated with a distal end section of the flexible lead portion of the adaptor for connection to an implantable pulse-generating device, such as, for example, an implantable pacemaker or defibrillator. Low resistance conductor wires electrically connect the connector assembly associated with the distal end section of the lead portion with the first and second receptacles of the adaptor housing.
摘要翻译： 公开了一种可植入引线适配器，其包括限定近端部分和远端部分的封装的热塑性壳体。 近端部分具有被配置为接收与第一可植入心脏引线相关联的第一类型的连接器组件的第一插座和被配置为接收与第二可植入心脏引线相关联的第二类型的连接器组件的第二插座。 细长的柔性引线部分从适配器壳体的远端部分延伸。 连接器组件可操作地与适配器的柔性引线部分的远端部分相连，用于连接到可植入的脉冲产生装置，例如可植入起搏器或去纤颤器。 低电阻导线将与引线部分的远端部分相关联的连接器组件与适配器壳体的第一和第二插座电连接。
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7.发明申请公开(公告)号：US20100137956A1
公开(公告)日：2010-06-03
申请号：US12590866
申请日：2009-11-16
申请人： Thomas P. Osypka
发明人： Thomas P. Osypka
IPC分类号： A61N1/00
CPC分类号： H01R31/06 , A61N1/056 , H01R24/58 , H01R27/02 , H01R31/02 , H01R2107/00 , H01R2201/12
摘要： An implantable lead adaptor is disclosed that includes an encapsulated thermoplastic housing defining a proximal end portion and a distal end portion. The proximal end portion has a first receptacle configured to receive a first type of connector assembly associated with a first implantable cardiac lead, and a second receptacle configured to receive a second type of connector assembly associated with a second implantable cardiac lead. An elongated flexible lead portion extends from the distal end portion of the adaptor housing. A connector assembly is operatively associated with a distal end section of the flexible lead portion of the adaptor for connection to an implantable pulse-generating device, such as, for example, an implantable pacemaker or defibrillator. Low resistance conductor wires electrically connect the connector assembly associated with the distal end section of the lead portion with the first and second receptacles of the adaptor housing.
摘要翻译： 公开了一种可植入引线适配器，其包括限定近端部分和远端部分的封装的热塑性壳体。 近端部分具有被配置为接收与第一可植入心脏引线相关联的第一类型的连接器组件的第一插座和被配置为接收与第二可植入心脏引线相关联的第二类型的连接器组件的第二插座。 细长的柔性引线部分从适配器壳体的远端部分延伸。 连接器组件可操作地与适配器的柔性引线部分的远端部分相连，用于连接到可植入的脉冲产生装置，例如可植入起搏器或去纤颤器。 低电阻导线将与引线部分的远端部分相关联的连接器组件与适配器壳体的第一和第二插座电连接。
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公开(公告)号：US20090076566A1
公开(公告)日：2009-03-19
申请号：US12172211
申请日：2008-07-11
申请人： Thomas P. Osypka , Hyoung-Ihl Kim , Yong-Il Shin , Hyo-Joon Kim
发明人： Thomas P. Osypka , Hyoung-Ihl Kim , Yong-Il Shin , Hyo-Joon Kim
CPC分类号： A61N1/0531
摘要： An epidural cortical stimulation system includes a stimulation body and a connecting lead. The stimulation body has a core formed of a shape-memory material, insulation provided around the core, defining an outer surface of the stimulation body, and at least one electrode arranged on the outer surface of the stimulation body, adapted and configured to contact the dura of a patient. The connecting lead extends from a proximal end of the body, and is adapted and configured for electrical communication with a control unit for providing power to the body electrical cortical stimulation.
摘要翻译： 硬膜外皮质刺激系统包括刺激体和连接引线。 刺激体具有由形状记忆材料形成的芯，设置在芯周围的绝缘体，限定刺激体的外表面，以及布置在刺激体的外表面上的至少一个电极，适于并构造成接触 患者的硬脑膜 连接引线从主体的近端延伸，并且被适配和配置为与用于向身体电皮质刺激提供动力的控制单元电连通。
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公开(公告)号：USD582555S1
公开(公告)日：2008-12-09
申请号：US29292935
申请日：2007-11-01
申请人： Thomas P. Osypka
设计人： Thomas P. Osypka
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公开(公告)号：USD576276S1
公开(公告)日：2008-09-02
申请号：US29292120
申请日：2007-09-28
申请人： Thomas P. Osypka
设计人： Thomas P. Osypka
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