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1.发明授权Antibodies that bind human dendritic and epithelial cell 205 (DEC-205) 有权结合人树突状细胞和上皮细胞205（DEC-205）的抗体公开(公告)号：US08236318B2
公开(公告)日：2012-08-07
申请号：US12266745
申请日：2008-11-07
申请人： Tibor Keler , Lizhen He , Venky Ramakrishna , Laura A. Vitale
发明人： Tibor Keler , Lizhen He , Venky Ramakrishna , Laura A. Vitale
IPC分类号： A61K39/00 , A61K39/395
CPC分类号： C07K16/2851 , A61K2039/505 , C07K2317/21 , C07K2317/77 , C07K2317/92 , C07K2319/00
摘要： Isolated monoclonal antibodies which bind to human DEC-205 and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnostic methods for using the antibodies.
摘要翻译： 公开了结合人DEC-205和相关的基于抗体的组合物和分子的分离的单克隆抗体。 还公开了包含抗体的药物组合物，以及使用抗体的治疗和诊断方法。
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公开(公告)号：US08586720B2
公开(公告)日：2013-11-19
申请号：US13542909
申请日：2012-07-06
申请人： Tibor Keler , Lizhen He , Venky Ramakrishna , Laura A. Vitale
发明人： Tibor Keler , Lizhen He , Venky Ramakrishna , Laura A. Vitale
IPC分类号： C07H21/04
CPC分类号： C07K16/2851 , A61K2039/505 , C07K2317/21 , C07K2317/77 , C07K2317/92 , C07K2319/00
摘要： Isolated monoclonal antibodies which bind to human DEC-205 and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnostic methods for using the antibodies.
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3.发明授权Antibodies that bind human dendritic and epithelial cell 205 (DEC-205) 有权结合人树突状细胞和上皮细胞205（DEC-205）的抗体公开(公告)号：US08362214B2
公开(公告)日：2013-01-29
申请号：US12387654
申请日：2009-05-05
申请人： Tibor Keler , Lizhen He , Venky Ramakrishna , Laura A. Vitale
发明人： Tibor Keler , Lizhen He , Venky Ramakrishna , Laura A. Vitale
CPC分类号： C07K16/2851 , A61K2039/505 , C07K2317/21 , C07K2317/77 , C07K2317/92 , C07K2319/00
摘要： Isolated monoclonal antibodies which bind to human DEC-205 and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnostic methods for using the antibodies.
摘要翻译： 公开了结合人DEC-205和相关的基于抗体的组合物和分子的分离的单克隆抗体。 还公开了包含抗体的药物组合物，以及使用抗体的治疗和诊断方法。
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4.发明申请Antibodies that bind human dendritic and epithelial cell 205 (DEC-205) 有权结合人树突状细胞和上皮细胞205（DEC-205）的抗体公开(公告)号：US20100098704A1
公开(公告)日：2010-04-22
申请号：US12387654
申请日：2009-05-05
申请人： Tibor Keler , Lizhen He , Venky Ramakrishna , Laura A. Vitale
发明人： Tibor Keler , Lizhen He , Venky Ramakrishna , Laura A. Vitale
IPC分类号： A61K39/395 , C07K16/28 , C12N15/63 , C07K19/00
CPC分类号： C07K16/2851 , A61K2039/505 , C07K2317/21 , C07K2317/77 , C07K2317/92 , C07K2319/00
摘要： Isolated monoclonal antibodies which bind to human DEC-205 and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnostic methods for using the antibodies.
摘要翻译： 公开了结合人DEC-205和相关的基于抗体的组合物和分子的分离的单克隆抗体。 还公开了包含抗体的药物组合物，以及使用抗体的治疗和诊断方法。
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公开(公告)号：US20050180983A1
公开(公告)日：2005-08-18
申请号：US10903191
申请日：2004-07-30
申请人： Tibor Keler , Michael Endres , Lizhen He , Venky Ramakrishna
发明人： Tibor Keler , Michael Endres , Lizhen He , Venky Ramakrishna
IPC分类号： A61K39/00 , C07K14/59 , C07K16/28 , A61K39/395 , C07K16/46
CPC分类号： C07K16/2851 , A61K39/0006 , A61K39/0011 , A61K2039/5154 , A61K2039/572 , A61K2039/6056 , C07K14/59 , C07K16/28 , C07K2317/21 , C07K2317/33 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/77 , C07K2318/10 , C07K2319/00 , C07K2319/33 , Y02A50/401 , Y02A50/412 , Y02A50/469
摘要： The present invention provides novel antibody vaccine conjugates and methods of using the same to induce a cytotoxic T cell (CTL) response. In a particular, embodiment, the vaccine conjugate includes a human chorionic gonadotropin beta subunit (βhCG) antigen linked to an anti-mannose receptor (MR) antibody.
摘要翻译： 本发明提供新的抗体疫苗缀合物及其使用方法诱导细胞毒性T细胞（CTL）应答。 在具体的实施方案中，疫苗缀合物包括与抗甘露糖受体（MR）抗体连接的人绒毛膜促性腺激素β亚基（betahCG）抗原。
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公开(公告)号：US09259459B2
公开(公告)日：2016-02-16
申请号：US10903191
申请日：2004-07-30
申请人： Tibor Keler , Michael Endres , Lizhen He , Venky Ramakrishna
发明人： Tibor Keler , Michael Endres , Lizhen He , Venky Ramakrishna
CPC分类号： C07K16/2851 , A61K39/0006 , A61K39/0011 , A61K2039/5154 , A61K2039/572 , A61K2039/6056 , C07K14/59 , C07K16/28 , C07K2317/21 , C07K2317/33 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/77 , C07K2318/10 , C07K2319/00 , C07K2319/33 , Y02A50/401 , Y02A50/412 , Y02A50/469
摘要： The present invention provides novel antibody vaccine conjugates and methods of using the same to induce a cytotoxic T cell (CTL) response. In a particular, embodiment, the vaccine conjugate includes a human chorionic gonadotropin beta subunit (βhCG) antigen linked to an anti-mannose receptor (MR) antibody.
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公开(公告)号：US09243064B2
公开(公告)日：2016-01-26
申请号：US10769144
申请日：2004-01-30
申请人： Tibor Keler , Michael Endres , Lizhen He , Venky Ramakrishna
发明人： Tibor Keler , Michael Endres , Lizhen He , Venky Ramakrishna
CPC分类号： C07K16/2851 , A61K39/0006 , A61K39/0011 , A61K47/646 , A61K47/6811 , A61K47/6849 , A61K2039/5154 , A61K2039/6056 , C07K14/59 , C07K16/28 , C07K2317/622 , C07K2317/77 , C07K2319/00 , Y02A50/412
摘要： The present invention provides novel antibody vaccine conjugates and methods of using the same to induce a cytotoxic T cell (CTL) response. In a particular, embodiment, the vaccine conjugate includes a human chorionic gonadotropin beta subunit (βhCG) antigen linked to an anti-mannose receptor (MR) antibody.
摘要翻译： 本发明提供新的抗体疫苗缀合物及其使用方法诱导细胞毒性T细胞（CTL）应答。 在具体的实施方案中，疫苗缀合物包括与抗甘露糖受体（MR）抗体连接的人绒毛膜促性腺激素β亚基（＆bgr; hCG）抗原。
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8.发明授权公开(公告)号：US07083789B2
公开(公告)日：2006-08-01
申请号：US10006177
申请日：2001-12-04
申请人： Venky Ramakrishna , Mark M. Ross , Ramila Philip
发明人： Venky Ramakrishna , Mark M. Ross , Ramila Philip
IPC分类号： A61K39/00
CPC分类号： C07K14/705 , A61K39/00 , A61K2039/5158 , C07K14/47 , C07K14/4738 , C07K14/4748 , C07K14/485 , C07K14/70546 , C07K14/71
摘要： The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of cancer, especially carcinomas, such as ovarian carcinoma. The invention discloses peptides, polypeptides, and polynucleotides that can be used to stimulate a CTL response against cancer.
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9.发明授权Cytotoxic T-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer 有权用于癌症预防，治疗和诊断的细胞毒性T淋巴细胞诱导免疫原公开(公告)号：US07919467B2
公开(公告)日：2011-04-05
申请号：US11426161
申请日：2006-06-23
CPC分类号： A61K39/0011 , A61K9/127 , A61K38/18 , A61K38/19 , A61K39/00 , A61K2039/5154 , A61K2039/5158 , A61K2039/522 , A61K2039/53 , C07K14/47 , C07K14/4738 , C07K14/4748 , C07K14/485 , C07K14/705 , C07K14/70546 , C07K14/71 , C12N5/0636 , G01N33/57484 , A61K2300/00
摘要： The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of cancer, especially carcinomas, such as ovarian carcinoma. The invention discloses peptides, polypeptides, and polynucleotides that can be used to stimulate a CTL response against cancer.
摘要翻译： 本发明涉及用于预防，治疗和诊断癌症，特别是诸如卵巢癌的癌症的组合物和方法。 本发明公开了可用于刺激针对癌症的CTL应答的肽，多肽和多核苷酸。
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10.发明申请CYTOTOXIC T-LYMPHOCYTE-INDUCING IMMUNOGENS FOR PREVENTION, TREATMENT, AND DIAGNOSIS OF CANCER 有权CYTOTOXIC T淋巴细胞诱导免疫调节因子预防，治疗和诊断癌症公开(公告)号：US20080207497A1
公开(公告)日：2008-08-28
申请号：US11426161
申请日：2006-06-23
CPC分类号： A61K39/0011 , A61K9/127 , A61K38/18 , A61K38/19 , A61K39/00 , A61K2039/5154 , A61K2039/5158 , A61K2039/522 , A61K2039/53 , C07K14/47 , C07K14/4738 , C07K14/4748 , C07K14/485 , C07K14/705 , C07K14/70546 , C07K14/71 , C12N5/0636 , G01N33/57484 , A61K2300/00
摘要： The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of cancer, especially carcinomas, such as ovarian carcinoma. The invention discloses peptides, polypeptides, and polynucleotides that can be used to stimulate a CTL response against cancer.
摘要翻译： 本发明涉及用于预防，治疗和诊断癌症，特别是诸如卵巢癌的癌症的组合物和方法。 本发明公开了可用于刺激针对癌症的CTL应答的肽，多肽和多核苷酸。
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