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公开(公告)号：US09499826B2
公开(公告)日：2016-11-22
申请号：US13701933
申请日：2011-05-30
申请人： Tiina Pakula , Markku Saloheimo , Mari Hakkinen , Ann Westerholm-Parvinen , Merja Penttila , Marika Vitikainen
发明人： Tiina Pakula , Markku Saloheimo , Mari Hakkinen , Ann Westerholm-Parvinen , Merja Penttila , Marika Vitikainen
CPC分类号： C12N15/80 , C07K14/37 , C12N9/16 , C12N9/2437 , C12N9/2477 , C12P1/02 , C12P21/00 , Y02P20/52
摘要： The present invention relates to a method for genetically modifying a filamentous fungus host for improved protein production. The method comprises that a filamentous fungus host is genetically modified to be deficient or to overexpress specific genes. The invention relates also to the modified hosts. Furthermore, the invention relates to a method for improved production or for producing an improved composition of proteins, such as cellulases, hemicellulases, other proteins involved in the degradation of lignocellulosic material, or other proteins, in a filamentous fungus host.
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公开(公告)号：US20130244276A1
公开(公告)日：2013-09-19
申请号：US13701933
申请日：2011-05-30
申请人： Tiina Pakula , Markku Saloheimo , Mari Hakkinen , Ann Westerholm-Parvinen , Merja Penttila , Marika Vitikainen
发明人： Tiina Pakula , Markku Saloheimo , Mari Hakkinen , Ann Westerholm-Parvinen , Merja Penttila , Marika Vitikainen
CPC分类号： C12N15/80 , C07K14/37 , C12N9/16 , C12N9/2437 , C12N9/2477 , C12P1/02 , C12P21/00 , Y02P20/52
摘要： The present invention relates to a method for genetically modifying a filamentous fungus host for improved protein production. The method comprises that a filamentous fungus host is genetically modified to be deficient or to overexpress specific genes. The invention relates also to the modified hosts. Furthermore, the invention relates to a method for improved production or for producing an improved composition of proteins, such as cellulases, hemicellulases, other proteins involved in the degradation of lignocellulosic material, or other proteins, in a filamentous fungus host.
摘要翻译： 本发明涉及用于遗传修饰丝状真菌宿主以改善蛋白质生产的方法。 该方法包括将丝状真菌宿主遗传修饰为缺陷或过表达特定基因。 本发明还涉及修饰的宿主。 此外，本发明涉及一种用于在丝状真菌宿主中改进生产或用于产生改进的蛋白质组合物的方法，例如纤维素酶，半纤维素酶，参与木质纤维素材料降解的其它蛋白质或其它蛋白质。
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公开(公告)号：US20130078674A1
公开(公告)日：2013-03-28
申请号：US13701894
申请日：2011-05-30
申请人： Tiina Pakula , Markku Saloheimo , Mari Hakkinen , Ann Westerholm-Parvinen , Merja Penttila , Marika Vitikainen
发明人： Tiina Pakula , Markku Saloheimo , Mari Hakkinen , Ann Westerholm-Parvinen , Merja Penttila , Marika Vitikainen
CPC分类号： C12N9/48 , C07K14/37 , C12N9/00 , C12N9/16 , C12N9/2402 , C12N9/2437 , C12N9/244 , C12N9/2477 , C12N15/80 , C12P21/00 , C12Y302/01004 , C12Y302/01006 , C12Y302/01091 , Y02P20/52
摘要： The present invention relates to a method for genetically modifying a filamentous fungus host for improved protein production. The method comprises that a filamentous fungus host is genetically modified to overexpress or to be deficient of specific genes. The invention relates also to the modified hosts. Furthermore, the invention relates to a method for improved production or for producing an improved composition of proteins, such as cellulases, hemicellulases, other proteins involved in the degradation of lignocellulosic material, or other proteins, in a filamentous fungus host.
摘要翻译： 本发明涉及用于遗传修饰丝状真菌宿主以改善蛋白质生产的方法。 该方法包括丝状真菌宿主被遗传修饰以过表达或缺乏特定基因。 本发明还涉及修饰的宿主。 此外，本发明涉及一种用于在丝状真菌宿主中改进生产或用于产生改进的蛋白质组合物的方法，例如纤维素酶，半纤维素酶，参与木质纤维素材料降解的其它蛋白质或其它蛋白质。
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公开(公告)号：US09512415B2
公开(公告)日：2016-12-06
申请号：US13701894
申请日：2011-05-30
申请人： Tiina Pakula , Markku Saloheimo , Mari Hakkinen , Ann Westerholm-Parvinen , Merja Penttila , Marika Vitikainen
发明人： Tiina Pakula , Markku Saloheimo , Mari Hakkinen , Ann Westerholm-Parvinen , Merja Penttila , Marika Vitikainen
IPC分类号： C12P21/02 , C12N9/48 , C07K14/37 , C12N15/80 , C12N9/00 , C12N9/16 , C12N9/24 , C12N9/42 , C12P21/00
CPC分类号： C12N9/48 , C07K14/37 , C12N9/00 , C12N9/16 , C12N9/2402 , C12N9/2437 , C12N9/244 , C12N9/2477 , C12N15/80 , C12P21/00 , C12Y302/01004 , C12Y302/01006 , C12Y302/01091 , Y02P20/52
摘要： The present invention relates to a method for genetically modifying a filamentous fungus host for improved protein production. The method comprises that a filamentous fungus host is genetically modified to overexpress or to be deficient of specific genes. The invention relates also to the modified hosts. Furthermore, the invention relates to a method for improved production or for producing an improved composition of proteins, such as cellulases, hemicellulases, other proteins involved in the degradation of lignocellulosic material, or other proteins, in a filamentous fungus host.
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公开(公告)号：US09487791B2
公开(公告)日：2016-11-08
申请号：US13701919
申请日：2011-05-30
申请人： Tiina Pakula , Markku Saloheimo , Mari Hakkinen , Ann Westerholm-Parvinen , Merja Penttila , Marika Vitikainen
发明人： Tiina Pakula , Markku Saloheimo , Mari Hakkinen , Ann Westerholm-Parvinen , Merja Penttila , Marika Vitikainen
CPC分类号： C12N15/80 , C12N9/2437 , C12N9/244 , C12N9/2445 , C12N9/2477 , C12N9/248 , C12N15/52 , C12Y302/01004 , C12Y302/01006 , C12Y302/01021 , C12Y302/01091
摘要： The present invention relates to a method for genetically modifying a filamentous fungus host for improved protein production. The method comprises that a filamentous fungus host is genetically modified to overexpress or to be deficient of specific genes. The invention relates also to the modified hosts. Furthermore, the invention relates to a method for improved production or for producing an improved composition of proteins, such as cellulases, hemicellulases, other proteins involved in the degradation of lignocellulosic material, or other proteins, in a filamentous fungus host.
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公开(公告)号：US20130084604A1
公开(公告)日：2013-04-04
申请号：US13701919
申请日：2011-05-30
申请人： Tiina Pakula , Markku Saloheimo , Mari Hakkinen , Ann Westerholm-Parvinen , Merja Penttila , Marika Vitikainen
发明人： Tiina Pakula , Markku Saloheimo , Mari Hakkinen , Ann Westerholm-Parvinen , Merja Penttila , Marika Vitikainen
IPC分类号： C12N15/52
CPC分类号： C12N15/80 , C12N9/2437 , C12N9/244 , C12N9/2445 , C12N9/2477 , C12N9/248 , C12N15/52 , C12Y302/01004 , C12Y302/01006 , C12Y302/01021 , C12Y302/01091
摘要： The present invention relates to a method for genetically modifying a filamentous fungus host for improved protein production. The method comprises that a filamentous fungus host is genetically modified to overexpress or to be deficient of specific genes. The invention relates also to the modified hosts. Furthermore, the invention relates to a method for improved production or for producing an improved composition of proteins, such as cellulases, hemicellulases, other proteins involved in the degradation of lignocellulosic material, or other proteins, in a filamentous fungus host.
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公开(公告)号：US08546115B2
公开(公告)日：2013-10-01
申请号：US12668313
申请日：2008-07-08
申请人： Johanna Buchert , Tiina Nakari-Setälä , Pasi Halonen , Hanna Kontkanen , Ann Westerholm-Parvinen , Marjaana Rättö
发明人： Johanna Buchert , Tiina Nakari-Setälä , Pasi Halonen , Hanna Kontkanen , Ann Westerholm-Parvinen , Marjaana Rättö
IPC分类号： C12N9/18
CPC分类号： C12N9/18 , A23L5/25 , C11D3/386 , C12Y301/01 , C12Y301/01074 , D06M16/003 , D06M2101/32
摘要： The present invention relates to polyesterases having cutinase and/or suberinase activity obtainable from Coprinus and Trichoderma. The invention further relates to a method for producing the polyesterases, and to polynucleotides, vectors and host cells used therein. The enzymes are useful in hydrolysing cutin, suberin and other polyesters for example in treating agricultural or food raw materials, or wood raw materials, pulp and paper products and waste, and in modifying polyester fibers, or in laundry and dish applications.
摘要翻译： 本发明涉及具有从鬼伞属和木霉属获得的角质酶和/或辛草林酶活性的聚酯酶。 本发明还涉及生产聚酯酶的方法，以及其中使用的多核苷酸，载体和宿主细胞。 酶可用于水解角质，桧木和其他聚酯，例如用于处理农业或食品原料，或木材原料，纸浆和纸制品和废物，以及改性聚酯纤维，或在洗衣和盘子应用中。
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公开(公告)号：US20100209985A1
公开(公告)日：2010-08-19
申请号：US12668313
申请日：2007-07-08
申请人： Johanna Buchert , Tiina Nakari-Setälä , Pasi Halonen , Hanna Kontkanen , Ann Westerholm-Parvinen , Marjaana Rättö
发明人： Johanna Buchert , Tiina Nakari-Setälä , Pasi Halonen , Hanna Kontkanen , Ann Westerholm-Parvinen , Marjaana Rättö
IPC分类号： C12N9/18 , C12N9/20 , C07H21/04 , C12N15/63 , C12N1/15 , C12P7/40 , C12S3/00 , C12S11/00 , C12S9/00
CPC分类号： C12N9/18 , A23L5/25 , C11D3/386 , C12Y301/01 , C12Y301/01074 , D06M16/003 , D06M2101/32
摘要： The present invention relates to polyesterases having cutinase and/or suberinase activity obtainable from Coprinus and Trichoderma. The invention further relates to a method for producing the polyesterases, and to polynucleotides, vectors and host cells used therein. The enzymes are useful in hydrolysing cutin, suberin and other polyesters for example in treating agricultural or food raw materials, or wood raw materials, pulp and paper products and waste, and in modifying polyester fibers, or in laundry and dish applications.
摘要翻译： 本发明涉及具有从鬼伞属和木霉属获得的角质酶和/或辛草林酶活性的聚酯酶。 本发明还涉及生产聚酯酶的方法，以及其中使用的多核苷酸，载体和宿主细胞。 酶可用于水解角质，桧木和其他聚酯，例如用于处理农业或食品原料，或木材原料，纸浆和纸制品和废物，以及改性聚酯纤维，或在洗衣和盘子应用中。
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