公开(公告)号：US5338433A

公开(公告)日：1994-08-16

申请号：US77272

申请日：1993-06-17

申请人： George W. Maybee ,  Timothy E. Taylor ,  Elmer L. Field ,  Clyde Riley ,  William R. Lacefield, Jr. ,  Harold D. Coble ,  Harini Dasarathy

发明人： George W. Maybee ,  Timothy E. Taylor ,  Elmer L. Field ,  Clyde Riley ,  William R. Lacefield, Jr. ,  Harold D. Coble ,  Harini Dasarathy

IPC分类号： A61F2/00 ,  A61L27/30 ,  A61L27/32 ,  C25D3/56 ,  C25D15/02 ,  C25D13/02

CPC分类号： A61L27/306 ,  A61L27/32 ,  C25D15/02 ,  C25D3/562 ,  A61F2310/00796

摘要： Process for simultaneous electrodeposition of at least a two component alloy system of cobalt and chromium on a substrate, by providing an aqueous solution of divalent cobalt and trivalent chromium ions and containing ethylenediaminetetraacetic acid, at a pH of about 3 to about 5, electrolyzing the solution in an electrolyte cell containing an anode and a cathode, and codepositing cobalt and chromium on the cathode, e.g. titanium, as substrate. According to a preferred embodiment molybdenum-containing ions are also added to the electrolyte, resulting in codeposition of an alloy of cobalt, chromium and molybdenum. In another embodiment, a calcium phosphate ceramic such as hydroxyapatite (HA)is added to the above electrolyte solution, resulting, e.g. , in a codeposit of the calcium phosphate material, e.g. HA, and an alloy of cobalt, chromium and molybdenum. In still another embodiment, a calcium phosphate material such as HA, which has been previously attached to a substrate by sintering, is fixated by simultaneous electrodeposition of cobalt-chromium-molybdenum alloy, such codeposits having utility for improvement of medical implants.

摘要翻译： 通过在约3至约5的pH下提供二价钴和三价铬离子并含有乙二胺四乙酸的水溶液，同时在基底上同时电沉积钴和铬的至少两种组分合金体系，电解溶液 在含有阳极和阴极的电解质电池中，并且在阴极上共沉积钴和铬，例如， 钛作为底物。 根据优选实施方案，还将钼含离子加入到电解质中，导致钴，铬和钼的合金的共沉积。 在另一个实施方案中，将磷酸钙陶瓷如羟基磷灰石（HA）加入到上述电解质溶液中， 在磷酸钙材料的共沉积物中，例如， HA和钴，铬和钼的合金。 在另一个实施方案中，通过同时电沉积钴 - 铬 - 钼合金，已经预先通过烧结附着到基底上的磷酸钙材料如HA来固定，这种共沉积可用于医疗植入物的改进。

公开(公告)号：US5330826A

公开(公告)日：1994-07-19

申请号：US565936

申请日：1990-08-13

申请人： Timothy E. Taylor ,  Clyde Riley ,  William R. Lacefield, Jr. ,  Harold D. Coble ,  George W. Maybee

发明人： Timothy E. Taylor ,  Clyde Riley ,  William R. Lacefield, Jr. ,  Harold D. Coble ,  George W. Maybee

IPC分类号： A61F2/00 ,  A61F2/30 ,  A61F2/32 ,  A61L27/30 ,  A61L27/32 ,  C25D15/02 ,  B32B5/32

CPC分类号： A61L27/32 ,  A61F2/30767 ,  A61L27/306 ,  C25D15/02 ,  A61F2/32 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00796 ,  Y10S623/92 ,  Y10T428/12535 ,  Y10T428/12611 ,  Y10T428/12771 ,  Y10T428/12806 ,  Y10T428/24975 ,  Y10T428/265

摘要： A metal substrate, e.g. titanium, having a calcium phosphate coating, particularly hydroxylapatite, and containing a metal such as cobalt, codeposited on the substrate by electrolyzing a cobalt salt, particularly cobalt sulfate, liquid electrolyte having a calcium phosphate material, particularly hydroxylapatite, suspended therein, employing a cobalt anode and the metal substrate as cathode. The particles of cobalt so codeposited with the particles of calcium phosphate material, e.g. hydroxylapatite, hold the latter particles strongly on the substrate metal. If desired, a second coating of the pure calcium phosphate material, e.g. "hydroxylapatite", optionally can be applied over the codeposited hydroxylapatite-cobalt coating. The calcium phosphate coated metal substrate of the invention, particularly the codeposited "hydroxylapatite"-cobalt coating, on a titanium or cobalt-chromium substrate, has particular value for application as medical implants, e.g. as hip prosthetics, and for high temperature high stressed applications.

摘要翻译： 金属基材，例如 钛，具有磷酸钙涂层，特别是羟基磷灰石，并且含有金属如钴，通过电解钴盐，特别是硫酸钴，共沉积在基材上，悬浮在其中的具有磷酸钙材料的电解质，特别是羟基磷灰石，使用钴 阳极和金属基板作为阴极。 这样的钴颗粒与磷酸钙材料的颗粒例如共沉积。 羟基磷灰石，将后者颗粒牢固地保留在基底金属上。 如果需要，可以将纯磷酸钙材料的第二次涂层，例如， “羟基磷灰石”，任选地可以施加在共沉积的羟基磷灰石钴涂层上。 本发明的磷酸钙涂覆的金属基底，特别是在钛或钴 - 铬基底上共沉积的“羟基磷灰石”钴涂层对于作为医疗植入物的应用具有特别的价值。 作为髋关节假体，以及用于高温高应力的应用。

公开(公告)号：US6045683A

公开(公告)日：2000-04-04

申请号：US980839

申请日：1997-12-01

申请人： Clyde Riley ,  Mukesh Kumar

发明人： Clyde Riley ,  Mukesh Kumar

IPC分类号： C25D9/08 ,  C25D9/02

CPC分类号： C25D9/08

摘要： The invention provides a brushite coating that is easily convertible to hydroxyapatite at mild conditions. The brushite coating is rapidly electrodeposited from an aqueous electrolyte solution of calcium phosphate, monobasic and salts having cations of ammonium, alkali metals and alkaline earth metals. About 1 to 5 percent of the calcium ions in the brushite coating are substituted with ammonium, alkali metals or alkaline earth metal cations. Hydroxyapatite can be formed by immersing the brushite coating in an animal or human body fluid or a simulated body fluid at from about 20 to 37.degree. C. Substantially stoichiometric calcium hydroxyapatite is formed.

摘要翻译： 本发明提供了一种在温和条件下易于转化为羟基磷灰石的白云石涂层。 从含磷酸钙，一元碱和含有铵，碱金属和碱土金属阳离子的盐的电解质水溶液中快速电沉积。 褐煤涂层中约1至5％的钙离子被铵，碱金属或碱土金属阳离子取代。 羟基磷灰石可以通过在约20至37℃下将挥发性涂层浸入动物或人体液或模拟体液中形成。形成基本化学计量的羟基磷灰石钙。