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公开(公告)号：US06921526B2
公开(公告)日：2005-07-26
申请号：US10122611
申请日：2002-04-12
IPC分类号： G01N33/566 , A61K38/00 , A61K51/00 , A61K51/08 , A61P35/00 , C07F5/00 , C07F15/00 , C07K7/06 , C07K7/08 , C07K14/575 , A61M36/14
CPC分类号： A61K51/088 , A61K38/00 , C07F5/003 , C07F15/008 , C07K7/086 , C07K14/57572
摘要： A compound for use as a therapeutic or diagnostic radiopharmaceutical includes a group capable of complexing a medically useful metal attached to a moiety which is capable of binding to a gastrin releasing peptide receptor. A method for treating a subject having a neoplastic disease includes administering to the subject an effective amount of a radiopharmaceutical having a metal chelated with a chelating group attached to a moiety capable of binding to a gastrin releasing peptide receptor expressed on tumor cells with subsequent internalization inside of the cell. A method of forming a therapeutic or diagnostic compound includes reacting a metal synthon with a chelating group covalently linked with a moiety capable of binding a gastrin releasing peptide receptor.
摘要翻译： 用作治疗或诊断性放射性药物的化合物包括能够使与能够结合胃泌素释放肽受体的部分连接的医学上有用的金属络合的基团。 用于治疗患有肿瘤疾病的受试者的方法包括向受试者施用有效量的具有与螯合基螯合的金属的放射性药物，所述螯合基团连接到能够结合肿瘤细胞上表达的胃泌素释放肽受体的部分，随后内化 的细胞。 形成治疗或诊断化合物的方法包括使金属合成酶与能够结合胃泌素释放肽受体的部分共价连接的螯合基团反应。
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公开(公告)号：US07147838B2
公开(公告)日：2006-12-12
申请号：US11025636
申请日：2004-12-29
IPC分类号： A61K49/00
CPC分类号： A61K51/088 , A61K38/00 , C07F5/003 , C07F15/008 , C07K7/086 , C07K14/57572
摘要： A compound for use as a therapeutic or diagnostic radiopharmaceutical includes a group capable of complexing a medically useful metal attached to a moiety which is capable of binding to a gastrin releasing peptide receptor. A method for treating a subject having a neoplastic disease includes administering to the subject an effective amount of a radiopharmaceutical having a metal chelated with a chelating group attached to a moiety capable of binding to a gastrin releasing peptide receptor expressed on tumor cells with subsequent internalization inside of the cell. A method of forming a therapeutic or diagnostic compound includes reacting a metal synthon with a chelating group covalently linked with a moiety capable of binding a gastrin releasing peptide receptor.
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公开(公告)号：US06200546B1
公开(公告)日：2001-03-13
申请号：US09064499
申请日：1998-04-22
IPC分类号： A61K4900
CPC分类号： A61K51/088 , A61K38/00 , C07F5/003 , C07F15/008 , C07K7/086 , C07K14/57572
摘要： A compound for use as a therapeutic or diagnostic radiopharmaceutical includes a group capable of complexing a medically useful metal attached to a moiety which is capable of binding to a gastrin releasing peptide receptor. A method for treating a subject having a neoplastic disease includes administering to the subject an effective amount of a radiopharmaceutical having a metal chelated with a chelating group attached to a moiety capable of binding to a gastrin releasing peptide receptor expressed on tumor cells with subsequent internalization inside of the cell. A method of forming a therapeutic or diagnostic compound includes reacting a metal synthon with a chelating group covalently linked with a moiety capable of binding a gastrin releasing peptide receptor.
摘要翻译： 用作治疗或诊断性放射性药物的化合物包括能够使与能够结合胃泌素释放肽受体的部分连接的医学上有用的金属络合的基团。 用于治疗患有肿瘤疾病的受试者的方法包括向受试者施用有效量的具有与螯合基螯合的金属的放射性药物，所述螯合基团连接到能够结合肿瘤细胞上表达的胃泌素释放肽受体的部分，随后内化 的细胞。 形成治疗或诊断化合物的方法包括使金属合成酶与能够结合胃泌素释放肽受体的部分共价连接的螯合基团反应。
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公开(公告)号：US20070065362A1
公开(公告)日：2007-03-22
申请号：US11592864
申请日：2006-11-03
IPC分类号： A61K51/00 , C07K14/575
CPC分类号： A61K51/088 , A61K38/00 , C07F5/003 , C07F15/008 , C07K7/086 , C07K14/57572
摘要： A compound for use as a therapeutic or diagnostic radiopharmaceutical includes a group capable of complexing a medically useful metal attached to a moiety which is capable of binding to a gastrin releasing peptide receptor. A method for treating a subject having a neoplastic disease includes administering to the subject an effective amount of a radiopharmaceutical having a metal chelated with a chelating group attached to a moiety capable of binding to a gastrin releasing peptide receptor expressed on tumor cells with subsequent internalization inside of the cell. A method of forming a therapeutic or diagnostic compound includes reacting a metal synthon with a chelating group covalently linked with a moiety capable of binding a gastrin releasing peptide receptor.
摘要翻译： 用作治疗或诊断性放射性药物的化合物包括能够使与能够结合胃泌素释放肽受体的部分连接的医学上有用的金属络合的基团。 用于治疗患有肿瘤疾病的受试者的方法包括向受试者施用有效量的具有与螯合基螯合的金属的放射性药物，所述螯合基团连接到能够结合肿瘤细胞上表达的胃泌素释放肽受体的部分，随后内化 的细胞。 形成治疗或诊断化合物的方法包括使金属合成酶与能够结合胃泌素释放肽受体的部分共价连接的螯合基团反应。
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公开(公告)号：US20050163710A1
公开(公告)日：2005-07-28
申请号：US11025636
申请日：2004-12-29
IPC分类号： G01N33/566 , A61K38/00 , A61K51/00 , A61K51/08 , A61P35/00 , C07F5/00 , C07F15/00 , C07K7/06 , C07K7/08 , C07K14/575 , C07K14/79
CPC分类号： A61K51/088 , A61K38/00 , C07F5/003 , C07F15/008 , C07K7/086 , C07K14/57572
摘要： A compound for use as a therapeutic or diagnostic radiopharmaceutical includes a group capable of complexing a medically useful metal attached to a moiety which is capable of binding to a gastrin releasing peptide receptor. A method for treating a subject having a neoplastic disease includes administering to the subject an effective amount of a radiopharmaceutical having a metal chelated with a chelating group attached to a moiety capable of binding to a gastrin releasing peptide receptor expressed on tumor cells with subsequent internalization inside of the cell. A method of forming a therapeutic or diagnostic compound includes reacting a metal synthon with a chelating group covalently linked with a moiety capable of binding a gastrin releasing peptide receptor.
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公开(公告)号：US10263186B2
公开(公告)日：2019-04-16
申请号：US12843949
申请日：2010-07-27
申请人： Stephen R. Forrest , Ning Li
发明人： Stephen R. Forrest , Ning Li
摘要： A method of making a bulk heterojunction organic photovoltaic cell by glancing angle deposition. As the disclosed method relies on a trajectory of incident vapor flux that is not parallel to the substrate normal, micro and nano-scale columnar structures of thin films can be grown on the substrate. There is also disclosed a method of forming a donor-acceptor heterojunction by depositing at least one additional organic material over the columnar structures.
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公开(公告)号：US09665081B2
公开(公告)日：2017-05-30
申请号：US14369005
申请日：2012-01-29
申请人： Jianming Liu , Jiye Wang , Ning Li , Fengyu Wang , Liang Wu , Aimei Yan
发明人： Jianming Liu , Jiye Wang , Ning Li , Fengyu Wang , Liang Wu , Aimei Yan
CPC分类号： G05B15/02 , G06Q10/00 , G06Q50/06 , H02J3/14 , H02J13/00 , Y02B70/3225 , Y02E40/76 , Y02P80/10 , Y02P80/11 , Y02P80/114 , Y04S10/545 , Y04S20/222
摘要： A system for intelligent electric power utilization of park and a method thereof are provided. The system includes an acquisition system, a data processing system, an application system and a service system through which the acquisition system, the data processing system and the application system are connected to external system. The application system includes an intelligent interaction application subsystem, an electric power utilization monitoring application subsystem, an energy efficiency analysis application subsystem, an orderly electric power utilization application subsystem, a system security application subsystem and a man-machine interaction interface. Enterprise users are leaded to actively carry out requirement response. Energy conservation and emission reduction and peak shaving and valley filling are effectively realized in intelligent park. Capability of intelligent electric power utilization of the park is improved. Accordingly, load balancing capability of region is improved and safe and stable operation of the power grid is ensured.
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公开(公告)号：US09374646B2
公开(公告)日：2016-06-21
申请号：US13601573
申请日：2012-08-31
申请人： Ning Li
发明人： Ning Li
IPC分类号： H04R25/00 , G10L21/0332 , G10L21/0364 , G10L25/90
CPC分类号： H04R25/50 , G10L21/0332 , G10L21/0364 , G10L25/90 , H04R25/552
摘要： Disclosed herein, among other things, are methods and apparatus for binaural enhancement of tone language for hearing assistance devices. One aspect of the present subject matter includes a method for enhancing pitch in a hearing assistance system having a first and second hearing assistance device. A signal is received using a microphone of the first hearing assistance device. Pitch detection is performed on the signal to obtain a pitch value. The pitch value is wirelessly transmitted from the first hearing assistance device to the second hearing assistance device. In various embodiments, the pitch value of the first hearing assistance device is combined with a pitch value of the second hearing assistance device. The gain is adjusted based on the combined pitch value, in various embodiments.
摘要翻译： 这里公开的是用于听力辅助装置的双音增强语音的方法和装置。 本主题的一个方面包括一种用于在具有第一和第二听力辅助装置的助听系统中增强俯仰的方法。 使用第一听力辅助装置的麦克风接收信号。 对信号进行间距检测以获得音调值。 音调值从第一听力辅助装置无线地发送到第二听力辅助装置。 在各种实施例中，第一助听装置的音调值与第二听力辅助装置的音调值组合。 在各种实施例中，基于组合的音调值来调整增益。
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公开(公告)号：US20140351285A1
公开(公告)日：2014-11-27
申请号：US14369082
申请日：2012-01-18
申请人： Jianming Liu , Jiye Wang , Ning Li , Pengzhan Fan , Fengyu Wang , Houlei Lv , Xiaozhen Li
发明人： Jianming Liu , Jiye Wang , Ning Li , Pengzhan Fan , Fengyu Wang , Houlei Lv , Xiaozhen Li
CPC分类号： G06F16/2471 , G06N20/00 , G06Q30/0202 , G06Q50/06
摘要： Disclosed are a platform and method for analyzing electric power system data. The platform uses a cloud-distributed database to store data to be processed, performs, based on a received operating command, immediate inquiry and/or multi-dimensional analysis and/or machine learning and the like on the data to be processed so as to analyze said data, and achieves knowledge mining of said data through machine learning algorithm analysis. Through the platform and method for analyzing electric power system data disclosed in the present invention, unknown and valuable data can be extracted using a machine learning algorithm, thereby providing advantageous support for enterprise decisions.
摘要翻译： 公开了用于分析电力系统数据的平台和方法。 平台使用云分布数据库来存储要处理的数据，基于接收到的操作命令，立即询问和/或多维分析和/或机器学习等对待处理的数据进行处理，以便 分析所述数据，通过机器学习算法分析实现所述数据的知识挖掘。 通过本发明公开的用于分析电力系统数据的平台和方法，可以使用机器学习算法提取未知且有价值的数据，从而为企业决策提供有利的支持。
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公开(公告)号：US08892650B2
公开(公告)日：2014-11-18
申请号：US13539399
申请日：2012-06-30
CPC分类号： G06Q30/0269 , G06Q30/0241 , G06Q50/01
摘要： To provide a sponsored story unit, the social networking system receives a story request from an advertiser. The story request specifies properties of content used to generate the sponsored story. When the social networking system stores an object or an action performed on an object, properties associated with, and describing, the object or the action are also stored. For example, properties of an object include an object type, an object identifier, metadata describing the object or other suitable information. The social networking system identifies actions or objects associated with users connected to a viewing user having one or more properties included in a story request. A sponsored story is generated from the identified actions or objects and presented to a viewing user.
摘要翻译： 为了提供一个赞助的故事单元，社交网络系统收到广告商的故事请求。 故事要求指定用于生成赞助故事的内容的属性。 当社交网络系统存储对象或对对象执行的动作时，还存储与对象或动作相关联并描述对象或动作的属性。 例如，对象的属性包括对象类型，对象标识符，描述对象的元数据或其他合适的信息。 社交网络系统识别与连接到具有包括在故事请求中的一个或多个属性的观看用户的用户相关联的动作或对象。 从所识别的动作或对象产生赞助故事并呈现给观看用户。
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