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1.发明授权公开(公告)号：US08961931B2
公开(公告)日：2015-02-24
申请号：US13081604
申请日：2011-04-07
申请人： Ting-Shien Duh , Wuu-Jyh Lin , Jenn-Tzong Chen , Li-Yuan Huang , Hsin-Ell Wang , Chuan-Lin Chen , Wen-Yi Chang , Hao-Wen Kao
发明人： Ting-Shien Duh , Wuu-Jyh Lin , Jenn-Tzong Chen , Li-Yuan Huang , Hsin-Ell Wang , Chuan-Lin Chen , Wen-Yi Chang , Hao-Wen Kao
CPC分类号： C07H15/18
摘要： A 18F-labeled monomeric galactose derivative is provided as a tomography probe. The derivative is a positron emission tomography (PET) probe. The derivative has high affinity and good stability in animal's body. The derivative can be an alternative glucose metabolism imaging agent used in clinic examination and quantification.
摘要翻译： 提供18F标记的单体半乳糖衍生物作为断层摄影探针。 该衍生物是正电子发射断层扫描（PET）探针。 该衍生物在动物体内具有高亲和力和稳定性。 该衍生物可用于临床检查和定量中使用的替代性葡萄糖代谢显像剂。
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2.发明申请公开(公告)号：US20120259102A1
公开(公告)日：2012-10-11
申请号：US13081604
申请日：2011-04-07
申请人： Ting-Shien Duh , Wuu-Jyh Lin , Jenn-Tzong Chen , Li-Yuan Huang , Hsin-Ell Wang , Chuan-Lin Chen , Wen-Yi Chang , Hao-Wen Kao
发明人： Ting-Shien Duh , Wuu-Jyh Lin , Jenn-Tzong Chen , Li-Yuan Huang , Hsin-Ell Wang , Chuan-Lin Chen , Wen-Yi Chang , Hao-Wen Kao
IPC分类号： C07H15/18
CPC分类号： C07H15/18
摘要： A 18F-labeled monomeric galactose derivative is provided as a tomography probe. The derivative is a positron emission tomography (PET) probe. The derivative has high affinity and good stability in animal's body. The derivative can be an alternative glucose metabolism imaging agent used in clinic examination and quantification.
摘要翻译： 提供18F标记的单体半乳糖衍生物作为断层摄影探针。 该衍生物是正电子发射断层扫描（PET）探针。 该衍生物在动物体内具有高亲和力和稳定性。 该衍生物可用于临床检查和定量中使用的替代性葡萄糖代谢显像剂。
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公开(公告)号：US20130072672A1
公开(公告)日：2013-03-21
申请号：US13237067
申请日：2011-09-20
申请人： Li-Yuan Huang , Yen-Hung Tu , Wen-Chin Su , Jenn-Tzong Chen , Ting-Shien Duh , Wuu-Jyh Lin
发明人： Li-Yuan Huang , Yen-Hung Tu , Wen-Chin Su , Jenn-Tzong Chen , Ting-Shien Duh , Wuu-Jyh Lin
IPC分类号： C07H21/00
CPC分类号： C07H19/06
摘要： The present invention establishes a fast and simple [F-18] FLT synthesis process. Solid extraction units are used for purification to achieve an equally high and constant radiochemical yield and purity in a short period of time. By using a separation method, the impurities are reduced successfully while the total synthesis time is shortened. The radiochemical purity and the corrected radiochemical yield are both high.
摘要翻译： 本发明建立了快速简单的[F-18] FLT合成方法。 固体提取单元用于纯化，以在短时间内实现同样高且恒定的放射化学产率和纯度。 通过使用分离方法，在总合成时间缩短的同时成功地降低杂质。 放射化学纯度和校正放射化学产率都很高。
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公开(公告)号：US09163054B2
公开(公告)日：2015-10-20
申请号：US13237067
申请日：2011-09-20
申请人： Li-Yuan Huang , Yen-Hung Tu , Wen-Chin Su , Jenn-Tzong Chen , Ting-Shien Duh , Wuu-Jyh Lin
发明人： Li-Yuan Huang , Yen-Hung Tu , Wen-Chin Su , Jenn-Tzong Chen , Ting-Shien Duh , Wuu-Jyh Lin
CPC分类号： C07H19/06
摘要： The present invention establishes a fast and simple [F-18] FLT synthesis process. Solid extraction units are used for purification to achieve an equally high and constant radiochemical yield and purity in a short period of time. By using a separation method, the impurities are reduced successfully while the total synthesis time is shortened. The radiochemical purity and the corrected radiochemical yield are both high.
摘要翻译： 本发明建立了快速简单的[F-18] FLT合成方法。 固体提取单元用于纯化，以在短时间内实现同样高且恒定的放射化学产率和纯度。 通过使用分离方法，在总合成时间缩短的同时成功地降低杂质。 放射化学纯度和校正放射化学产率都很高。
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公开(公告)号：US20080041719A1
公开(公告)日：2008-02-21
申请号：US11500936
申请日：2006-08-09
申请人： Wuu-Jyh Lin , Mao-Hsung Chang , Ping-Yen Huang , Jenn-Tzong Chen , Ting-Shien Duh , Dow-Che Chen , Kuo-Yuan Chu
发明人： Wuu-Jyh Lin , Mao-Hsung Chang , Ping-Yen Huang , Jenn-Tzong Chen , Ting-Shien Duh , Dow-Che Chen , Kuo-Yuan Chu
IPC分类号： C23C14/00
CPC分类号： H01J37/3497 , H01J37/3435
摘要： A liquid and a gas is constantly filled into a target chamber of a target. Then the liquid and the gas flow around the chamber and are flown out. By doing so, the target is effectively cooled down.
摘要翻译： 液体和气体不断地被填充到目标的靶室中。 然后液体和气体流过室并流出。 通过这样做，目标被有效地冷却下来。
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公开(公告)号：US07678248B2
公开(公告)日：2010-03-16
申请号：US11500936
申请日：2006-08-09
申请人： Wuu-Jyh Lin , Mao-Hsung Chang , Ping-Yen Huang , Jenn-Tzong Chen , Ting-Shien Duh , Dow-Che Chen , Kuo-Yuan Chu
发明人： Wuu-Jyh Lin , Mao-Hsung Chang , Ping-Yen Huang , Jenn-Tzong Chen , Ting-Shien Duh , Dow-Che Chen , Kuo-Yuan Chu
IPC分类号： C23C14/00
CPC分类号： H01J37/3497 , H01J37/3435
摘要： A liquid and a gas is constantly filled into a target chamber of a target. Then the liquid and the gas flow around the chamber and are flown out. By doing so, the target is effectively cooled down.
摘要翻译： 液体和气体不断地被填充到目标的靶室中。 然后液体和气体流过室并流出。 通过这样做，目标被有效地冷却下来。
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公开(公告)号：US20090211917A1
公开(公告)日：2009-08-27
申请号：US11500931
申请日：2006-08-09
申请人： Wuu-Jyh Lin , Ting-Shien Duh , Ying-Ming Tsai , Sun-Rong Huang , Chien-Hsin Lu , Mao-Hsung Chang , Jenn-Tzong Chen
发明人： Wuu-Jyh Lin , Ting-Shien Duh , Ying-Ming Tsai , Sun-Rong Huang , Chien-Hsin Lu , Mao-Hsung Chang , Jenn-Tzong Chen
IPC分类号： C25B1/24
CPC分类号： G21G1/10 , G21G1/001 , G21G2001/0078
摘要： A radioisotope Tl-201 is produced. The process includes electroplating, irradiating, dissolving precipitating, ion exchanging, decaying and filtering. The Tl-201 obtained is a liquid having a high purity.
摘要翻译： 生产放射性同位素Tl-201。 该方法包括电镀，照射，溶解沉淀，离子交换，腐蚀和过滤。 得到的T1-201是纯度高的液体。
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公开(公告)号：US20100243082A1
公开(公告)日：2010-09-30
申请号：US11980743
申请日：2007-10-31
申请人： Wuu-Jyh Lin , Mao-Hsung Chang , Kuo-Yuan Chu , Dow-chi Chen , Ping-Yen Huang , Jenn-Tzong Chen , Ting-shien Duh
发明人： Wuu-Jyh Lin , Mao-Hsung Chang , Kuo-Yuan Chu , Dow-chi Chen , Ping-Yen Huang , Jenn-Tzong Chen , Ting-shien Duh
IPC分类号： F16K15/00
CPC分类号： B01J4/008 , Y10T137/7838
摘要： A liquid isotope delivery system includes a pressure-controlling unit, an input unit, a target chamber, a proton-radiating unit and a storage unit. The pressure-controlling unit includes a first regulating valve, a second regulating valve connected to the first regulating valve and a third regulating valve connected to the first regulating valve. The input unit is connected to the second regulating valve. The target chamber is connected to the third regulating valve and the input unit. The proton-radiating unit is located near the target chamber. The storage unit is connected to the target chamber.
摘要翻译： 液体同位素输送系统包括压力控制单元，输入单元，目标室，质子辐射单元和存储单元。 压力控制单元包括第一调节阀，连接到第一调节阀的第二调节阀和连接到第一调节阀的第三调节阀。 输入单元连接到第二调节阀。 目标腔室连接到第三调节阀和输入单元。 质子辐射单元位于目标室附近。 存储单元连接到目标室。
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公开(公告)号：US20080063571A1
公开(公告)日：2008-03-13
申请号：US11518411
申请日：2006-09-11
申请人： Wuu-Jyh Lin , Ting-Shien Duh , Ying-Ming Tsai , Sun-Rong Huang , Chien-Hsin Lu , Mao-Hsung Chang , Jenn-Tzong Chen
发明人： Wuu-Jyh Lin , Ting-Shien Duh , Ying-Ming Tsai , Sun-Rong Huang , Chien-Hsin Lu , Mao-Hsung Chang , Jenn-Tzong Chen
IPC分类号： B01L11/00
CPC分类号： G21G4/08
摘要： A device to rapidly obtain a solution of Pb(lead)-201 from a solution of a solid target material of Tl(thallium)-203. The solution of Pb-201 is then processed through a degeneration and an ion exchange to obtain in Tl-201 radioisotope.
摘要翻译： 从Tl（铊）-203的固体靶材的溶液中快速获得Pb（铅）-201溶液的装置。 然后通过退化和离子交换处理Pb-201的溶液，以获得Tl-201放射性同位素。
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公开(公告)号：US07578982B1
公开(公告)日：2009-08-25
申请号：US11500931
申请日：2006-08-09
申请人： Wuu-Jyh Lin , Ting-Shien Duh , Ying-Ming Tsai , Sun-Rong Huang , Chien-Hsin Lu , Mao-Hsung Chang , Jenn-Tzong Chen
发明人： Wuu-Jyh Lin , Ting-Shien Duh , Ying-Ming Tsai , Sun-Rong Huang , Chien-Hsin Lu , Mao-Hsung Chang , Jenn-Tzong Chen
CPC分类号： G21G1/10 , G21G1/001 , G21G2001/0078
摘要： A radioisotope TI-201 is produced. The process includes electroplating, irradiating, dissolving, precipitating, ion exchanging, decaying and filtering. The TI-201 obtained is a liquid having a high purity.
摘要翻译： 生产放射性同位素TI-201。 该方法包括电镀，照射，溶解，沉淀，离子交换，腐蚀和过滤。 获得的TI-201是具有高纯度的液体。
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