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公开(公告)号：US20090208584A1
公开(公告)日：2009-08-20
申请号：US11921664
申请日：2006-06-09
IPC分类号： A61K9/14 , A61K47/38 , A61K31/538
CPC分类号： A61K9/2095 , A61K9/1623 , A61K9/1652 , A61K9/2009 , A61K9/2018 , A61K9/2054 , A61K9/2077 , A61K9/2866 , A61K31/536
摘要： The solid preparation of the present invention aims at providing a solid preparation superior in the stability during production and preservation even when a poorly water-soluble substance having a low melting point is contained in a large amount, and also superior in the disintegration property and release property of a poorly water-soluble substance having a low melting point, after oral administration, and is characterized by the following 1) to 3): 1) containing a poorly water-soluble substance having a low melting point, a saccharide, and a cellulose selected from a crystalline cellulose and a low-substituted hydroxypropylcellulose, 2) a saccharide/cellulose weight ratio exceeding 2, and 3) a cellulose content of not less than 5 wt %.
摘要翻译： 本发明的固体制剂的目的在于提供即使在大量含有低熔点的难溶性水溶性物质的情况下，在制造和保存中的稳定性方面也优异的固体制剂，并且还具有优异的崩解性和脱模性 口服后具有低熔点的水溶性差的物质的性质，其特征在于以下1）〜3）：1）含有低熔点的水难溶性物质，糖类和 选自结晶纤维素和低取代羟丙基纤维素的纤维素，2）糖/纤维素重量比超过2，和3）纤维素含量不小于5重量％。
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公开(公告)号：US20080118552A1
公开(公告)日：2008-05-22
申请号：US11795734
申请日：2006-01-27
CPC分类号： A61K9/146 , A23L33/10 , A61K9/145 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K31/405 , A61K31/422 , A61K31/4422 , A61K31/64
摘要： A composition containing a poorly water soluble substance of the present invention is a composition having a median diameter of not more than 1 μm, comprising (i) a poorly water soluble substance and (ii) polyvinylpyrrolidone or a vinylpyrrolidone-vinyl acetate copolymer, and preferably, a composition having a median diameter of not more than 1 μm, comprising (i) a poorly water soluble substance, (ii) polyvinylpyrrolidone or a vinylpyrrolidone-vinyl acetate copolymer and (iii) an auxiliary dispersion stabilizer. By employing such constitution, a poorly water soluble substance is sufficiently micronized and a composition containing a poorly water soluble substance showing good absorbability of the poorly water soluble substance can be provided.A composition containing a poorly water soluble substance of the present invention can be prepared into a solid dosage form for oral administration in various forms such as tablet, powder, granule, capsule and the like. Therefore, using a composition containing a poorly water soluble substance of the present invention, for example, pharmaceutical preparations in various dosage forms showing good absorbability of a drug, which is a poorly water soluble substance, can be realized.
摘要翻译： 含有本发明的水溶性差的物质的组合物是中值粒径不大于1μm的组合物，其包含（i）水难溶性物质和（ii）聚乙烯吡咯烷酮或乙烯基吡咯烷酮 - 乙酸乙烯酯共聚物，优选 （i）水难溶性物质，（ii）聚乙烯吡咯烷酮或乙烯基吡咯烷酮 - 乙酸乙烯酯共聚物的组合物，和（iii）辅助分散稳定剂。 通过采用这种结构，水溶性差的物质被充分微粉化，并且可以提供含有水难溶性物质显示良好吸收性的难溶于水的物质的组合物。 含有本发明的水溶性差的物质的组合物可以制成固体剂型，用于各种形式的口服给药，例如片剂，粉剂，颗粒剂，胶囊剂等。 因此，使用含有本发明的水溶性差的物质的组合物，例如可以实现作为水难溶性物质的药物的吸收性良好的各种剂型的药物制剂。
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公开(公告)号：US08927011B2
公开(公告)日：2015-01-06
申请号：US12601158
申请日：2008-05-20
申请人： Hiroshi Suzuki , Tomohiro Yoshinari
发明人： Hiroshi Suzuki , Tomohiro Yoshinari
IPC分类号： A61K9/20 , A61K31/44 , A61K31/485 , A61K47/12
CPC分类号： A61K9/2013 , A61K9/2077 , A61K31/485 , A61K47/12
摘要： A process for advantageously producing tablets having an improved release property and an excellent stability to change with time is provided. The process is for producing tablets containing a morphinan compound represented by the Formula (I) below or pharmaceutically acceptable acid addition salt thereof and an acidic substance such as fumaric acid, maleic acid or adipic acid, and characterized in that the morphinan compound or a pharmaceutically acceptable acid addition salt thereof is granulated by wet granulation together with (an) excipient(s) prior to adding the acidic substance thereto.
摘要翻译： 提供了一种有利地制备具有改善的释放性能和优异的随时间变化的稳定性的片剂的方法。 该方法用于制备含有由下式（I）表示的吗啡喃化合物或其药学上可接受的酸加成盐和酸性物质如富马酸，马来酸或己二酸的片剂，其特征在于吗啡喃化合物或药学上可接受的盐 在将酸性物质加入其中之前，其可接受的酸加成盐与（a）赋形剂一起通过湿法制粒造粒。
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公开(公告)号：US08623405B2
公开(公告)日：2014-01-07
申请号：US11795734
申请日：2006-01-27
CPC分类号： A61K9/146 , A23L33/10 , A61K9/145 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K31/405 , A61K31/422 , A61K31/4422 , A61K31/64
摘要： The disclosed method involves preparation of a composition containing a poorly water soluble substance. The composition has a median diameter of not more than 1 μm, and includes (i) a poorly water soluble substance, (ii) polyvinylpyrrolidone or a vinylpyrrolidone-vinyl acetate copolymer, and (iii) an auxiliary dispersion stabilizer. By employing such constitution, a poorly water soluble substance is sufficiently micronized and a composition containing a poorly water soluble substance showing good absorbability of the poorly water soluble substance can be provided.
摘要翻译： 所公开的方法涉及制备含有水难溶性物质的组合物。 该组合物的中值粒径不大于1um，并且包括（i）水难溶性物质，（ii）聚乙烯吡咯烷酮或乙烯基吡咯烷酮 - 乙酸乙烯酯共聚物，和（iii）辅助分散稳定剂。 通过采用这种结构，水溶性差的物质被充分微粉化，并且可以提供含有水难溶性物质显示良好吸收性的难溶于水的物质的组合物。
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公开(公告)号：US4645688A
公开(公告)日：1987-02-24
申请号：US679460
申请日：1984-12-07
CPC分类号： C08G77/54 , C08G73/1042 , C08G73/106 , H01B3/303 , H01B3/46 , H01L23/296 , H01L2924/0002
摘要： There are disclosed a composition for protective coating material, preferably for a protective coating material of a semiconductor device which is constituted of principal elements of a semiconductor memory element, an encapsulating layer containing an inorganic material for encapsulating said element and a layer of a cured protective coating material arranged between said memory element and said encapsulating layer, which is composed of a polyamide acid obtained by the reaction of a diaminosiloxane, an organic diamine containing no silicon and an organic tetrabasic acid dianhydride, and a semiconductor device having a layer of a cured protective coating material composed of a polyimide-silicone copolymer obtained by dehydrating ring closure of the above-mentioned polyamide acid.
摘要翻译： 公开了一种用于保护涂层材料的组合物，优选用于半导体器件的保护涂层材料，其由半导体存储元件的主要元件，包含用于封装所述元件的无机材料的封装层和固化保护层 布置在所述存储元件和所述封装层之间的涂料，其由通过二氨基硅氧烷，不含硅的有机二胺和有机四元酸二酐反应获得的聚酰胺酸和具有固化的层的半导体器件 由通过上述聚酰胺酸脱水闭环得到的聚酰亚胺 - 硅氧烷共聚物构成的保护涂料。
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公开(公告)号：US4511705A
公开(公告)日：1985-04-16
申请号：US568284
申请日：1984-01-05
CPC分类号： C08G77/54 , C08G73/1042 , C08G73/106 , H01B3/303 , H01B3/46 , H01L23/296 , H01L2924/0002
摘要： There are disclosed a composition for protective coating material, preferably for a protective coating material of a semiconductor device which is constituted of principal elements of a semiconductor memory element, an encapsulating layer containing an inorganic material for encapsulating said element and a layer of a cured protective coating material arranged between said memory element and said encapsulating layer, which is composed of a polyamide acid obtained by the reaction of a diaminosiloxane, an organic diamine containing no silicon and an organic tetrabasic acid dianhydride, and a semiconductor device having a layer of a cured protective coating material composed of a polyimide-silicone copolymer obtained by dehydrating ring closure of the above-mentioned polyamide acid.
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公开(公告)号：US09871933B2
公开(公告)日：2018-01-16
申请号：US15370061
申请日：2016-12-06
申请人： Hiroshi Suzuki , Takao Suzuki
发明人： Hiroshi Suzuki , Takao Suzuki
CPC分类号： H04N1/0044 , G06F3/1208 , G06F3/1256 , G06F3/1294 , G06K15/1813 , G06K15/1822 , H04N1/00204 , H04N1/00344 , H04N2201/0039 , H04N2201/0094
摘要： An information processing apparatus is for generating image data by using drawing information for drawing an image. The information processing apparatus includes a print data acquirer configured to acquire print data including the drawing information from outside; a request acceptor configured to accept a request to display the image data of any page in the print data; a reader configured to read specific drawing information of pages in the print data up to a page before the any page accepted by the request acceptor, from a drawing information storage storing the specific drawing information, which is the drawing information that may be applied to the image data of pages after a page in which the drawing information is described, among the drawing information included in the print data; and a generator configured to generate the image data of the any page by applying the read specific drawing information.
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公开(公告)号：US09870185B2
公开(公告)日：2018-01-16
申请号：US15237560
申请日：2016-08-15
申请人： Hiroshi Suzuki , Toshiyuki Haginoya
发明人： Hiroshi Suzuki , Toshiyuki Haginoya
IPC分类号： G06F3/12
CPC分类号： G06F3/1288 , G06F3/1211 , G06F3/1219 , G06F3/1256 , G06F3/1286
摘要： A disclosed print manager server includes one or more processors and a memory configured to store a print management program. The processors execute the print management program to perform a process including analyzing an attribute of print data introduced, predicting a page of a preview image to be generated based on the analyzed attribute, a preview history of previous print jobs, and a preview prediction condition, generating the preview image of the predicted page, and providing the generated preview image in response to a request to display a preview.
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公开(公告)号：US09850913B2
公开(公告)日：2017-12-26
申请号：US14414856
申请日：2012-08-24
申请人： Byeongil An , Hiroshi Suzuki
发明人： Byeongil An , Hiroshi Suzuki
CPC分类号： F04D29/441 , F02M35/10157 , F02M35/10262 , F04D17/10 , F04D29/4213 , F04D29/444 , F04D29/685 , F05D2220/40 , F05D2250/51 , Y02T10/144 , Y02T10/146
摘要： An object is to position a plurality of guide vanes for generating swirl flow at a housing inner circumferential side in front of an impeller wheel to improve a surge margin and to restrict the decrease in a choke flow rate, thereby increasing an operation range of a compressor. A compressor 19 includes a compressor housing 15, an impeller wheel 7 which compresses intake gas flowing in from an intake-air inlet 23, a swirl-flow generating part including a plurality of guide vanes 55 disposed circumferentially along an inner circumferential wall of the intake-air channel 21 between the intake-air inlet 23 and the impeller wheel 7 and which swirls the intake gas from the intake-air inlet 23 around the rotational axis, and a central intake-air flow path 59 formed inside the guide vanes 55 to allow intake gas to flow to the impeller wheel 7 without passing through the guide vanes 55.
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公开(公告)号：US09581046B2
公开(公告)日：2017-02-28
申请号：US13813172
申请日：2011-12-22
申请人： Toru Hoshi , Isao Tomita , Motoki Ebisu , Hiroshi Suzuki , Takashi Shiraishi
发明人： Toru Hoshi , Isao Tomita , Motoki Ebisu , Hiroshi Suzuki , Takashi Shiraishi
CPC分类号： F01D25/24 , F04D29/441 , F04D29/681 , F05D2250/52
摘要： In a scroll structure of a centrifugal compressor, there are provided a radius increase arc portion E in which a radius from the center of a scroll 12 to a scroll centroid P of the cross section of the scroll 12 is gradually increased in any range in a circumferential direction from the start of winding of the scroll, and a radius decrease arc portion F in which the radius is gradually decreased toward a scroll end point Z.
摘要翻译： 在离心式压缩机的涡旋结构中，设置有半径增大圆弧部E，其中，涡旋件12的横截面的涡旋件12的中心部与涡形重心P的半径在 从涡卷的卷绕开始的圆周方向，半径减小圆弧部F朝向涡旋端点Z逐渐减小。
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