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公开(公告)号：US08404823B2
公开(公告)日：2013-03-26
申请号：US12447370
申请日：2007-10-26
申请人： Tomoyuki Sako , Emi Yasuda , Masaki Serata , Satoshi Matsumoto , Kan Shida
发明人： Tomoyuki Sako , Emi Yasuda , Masaki Serata , Satoshi Matsumoto , Kan Shida
CPC分类号： C12N15/52 , A23L33/135 , A61K38/00 , C12N9/1048 , C12P19/04
摘要： The invention provides a gene encoding a protein selected from among the following proteins (a) to (c): (a) a protein having any of the amino acid sequences of SEQ ID NOs: 2, 4, 6, 8, 10, 12, 14, 16, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102, 104, 106, and 108; (b) a protein which has an amino acid sequence equivalent to any of the amino acid sequences of (a), except that one to several amino acid residues are deleted, substituted, or added, and which exhibits cytokine production regulatory activity; and (c) a protein which has an amino acid sequence having 90% or higher identity to any of the amino acid sequences of (a), and which exhibits cytokine production regulatory activity, as well as a gene useful for regulating cytokine production and use of the gene.
摘要翻译： 本发明提供了编码选自以下蛋白质（a）〜（c）的蛋白质的基因：（a）具有SEQ ID NO：2,4,6,8,10,12的任意氨基酸序列的蛋白质 ，14，16，82，84，86，88，90，92，94，96，98，100，102，104，106及108; （b）具有与（a）的任何氨基酸序列相同的氨基酸序列的蛋白质，除了一至数个氨基酸残基被缺失，取代或添加，并且其表现出细胞因子产生调节活性; 和（c）具有与（a）的任何氨基酸序列具有90％或更高同一性并且表现出细胞因子产生调节活性的氨基酸序列的蛋白质，以及可用于调节细胞因子产生和使用的基因 的基因。
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公开(公告)号：US20100144551A1
公开(公告)日：2010-06-10
申请号：US12447370
申请日：2007-10-26
申请人： Tomoyuki Sako , Emi Yasuda , Masaki Serata , Satoshi Matsumoto , Kan Shida
发明人： Tomoyuki Sako , Emi Yasuda , Masaki Serata , Satoshi Matsumoto , Kan Shida
CPC分类号： C12N15/52 , A23L33/135 , A61K38/00 , C12N9/1048 , C12P19/04
摘要： The invention provides a gene encoding a protein selected from among the following proteins (a) to (c): (a) a protein having any of the amino acid sequences of SEQ ID NOs: 2, 4, 6, 8, 10, 12, 14, 16, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102, 104, 106, and 108; (b) a protein which has an amino acid sequence equivalent to any of the amino acid sequences of (a), except that one to several amino acid residues are deleted, substituted, or added, and which exhibits cytokine production regulatory activity; and (c) a protein which has an amino acid sequence having 90% or higher identity to any of the amino acid sequences of (a), and which exhibits cytokine production regulatory activity, as well as a gene useful for regulating cytokine production and use of the gene.
摘要翻译： 本发明提供了编码选自以下蛋白质（a）〜（c）的蛋白质的基因：（a）具有SEQ ID NO：2,4,6,8,10,12的任意氨基酸序列的蛋白质 ，14，16，82，84，86，88，90，92，94，96，98，100，102，104，106及108; （b）具有与（a）的任何氨基酸序列相同的氨基酸序列的蛋白质，除了一至数个氨基酸残基被缺失，取代或添加，并且其表现出细胞因子产生调节活性; 和（c）具有与（a）的任何氨基酸序列具有90％或更高同一性并且表现出细胞因子产生调节活性的氨基酸序列的蛋白质，以及可用于调节细胞因子产生和使用的基因 的基因。
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