公开(公告)号：US09238384B2

公开(公告)日：2016-01-19

申请号：US13752959

申请日：2013-01-29

Applicant: TOPPAN PRINTING CO., LTD.

Inventor： Kazuhiko Shiomitsu ,  Hiroshi Sugimura ,  Toshiaki Kurosu ,  Gaku Suzuki ,  Takao Tomono

IPC: B44C1/20 ,  B44C1/22 ,  A61M37/00 ,  B29C33/42 ,  B81C1/00

CPC classification number: B44C1/227 ,  A61M37/0015 ,  A61M2037/003 ,  A61M2037/0038 ,  A61M2037/0046 ,  A61M2037/0053 ,  B29C33/42 ,  B81B2201/055 ,  B81C1/00111 ,  B81C2201/0198

Abstract: The invention discloses a method of manufacturing a microneedle including the steps of forming an island etching mask having thickness distribution on a substrate, and processing the substrate into a needle by taking advantage of a difference in etching rates between the etching mask and the substrate. The invention enables to readily control a point angle and height of the manufactured needle.

公开(公告)号：US08876575B2

公开(公告)日：2014-11-04

申请号：US13649687

申请日：2012-10-11

Applicant: Toppan Printing Co., Ltd.

Inventor： Hiroshi Sugimura ,  Gaku Suzuki ,  Masahiro Ueno ,  Yoshihiro Kodama ,  Takao Tomono

IPC: B24B1/00 ,  B24B19/16 ,  B29C33/42 ,  B29C33/38 ,  A61M37/00 ,  B29L31/00

CPC classification number: B29C33/424 ,  A61M37/0015 ,  A61M2037/0053 ,  B09B3/0075 ,  B24B19/16 ,  B29C33/3842 ,  B29C33/3878 ,  B29L2031/7544 ,  B29L2031/756

Abstract: A method of manufacturing a microneedle including forming a plurality of first linear grooves on a substrate in parallel to one another along a first direction using grinding and forming a plurality of second linear grooves on the substrate in parallel to one another in a second direction intersecting the first direction using grinding. At least one of the forming of a plurality of first linear grooves and the forming of a plurality of second linear grooves includes forming first stage grooves using a first dicing blade; and processing the first stage grooves by tracing the first stage grooves using a second dicing blade having a side surface different from that of the first dicing blade to thereby form second stage grooves.

Abstract translation: 一种微针的制造方法，其特征在于，包括在基板上沿着第一方向彼此平行地形成多个第一线状槽，并且在与所述第二方向相交的第二方向上彼此平行地在所述基板上形成多个第二直线槽， 第一方向磨削。 形成多个第一直线槽和形成多个第二直线槽中的至少一个包括使用第一切割刀形成第一级槽; 并且通过使用具有与第一切割刀片的侧表面不同的侧表面的第二切割刀片来跟踪第一级槽来处理第一级槽，从而形成第二级槽。

公开(公告)号：US20130030374A1

公开(公告)日：2013-01-31

申请号：US13649687

申请日：2012-10-11

Applicant: TOPPAN PRINTING CO., LTD.

Inventor： Hiroshi SUGIMURA ,  Gaku Suzuki ,  Masahiro Ueno ,  Yoshihiro Kodama ,  Takao Tomono

IPC: B24B19/16 ,  A61M5/00

CPC classification number: B29C33/424 ,  A61M37/0015 ,  A61M2037/0053 ,  B09B3/0075 ,  B24B19/16 ,  B29C33/3842 ,  B29C33/3878 ,  B29L2031/7544 ,  B29L2031/756

Abstract: A method of manufacturing a microneedle including forming a plurality of first linear grooves on a substrate in parallel to one another along a first direction using grinding and forming a plurality of second linear grooves on the substrate in parallel to one another in a second direction intersecting the first direction using grinding. At least one of the forming of a plurality of first linear grooves and the forming of a plurality of second linear grooves includes forming first stage grooves using a first dicing blade; and processing the first stage grooves by tracing the first stage grooves using a second dicing blade having a side surface different from that of the first dicing blade to thereby form second stage grooves.

Abstract translation: 一种微针的制造方法，其特征在于，包括在基板上沿着第一方向彼此平行地形成多个第一线状槽，并且在与所述第二方向相交的第二方向上彼此平行地在所述基板上形成多个第二直线槽， 第一方向磨削。 形成多个第一直线槽和形成多个第二直线槽中的至少一个包括使用第一切割刀形成第一级槽; 并且通过使用具有与第一切割刀片的侧表面不同的侧表面的第二切割刀片来跟踪第一级槽来处理第一级槽，从而形成第二级槽。