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公开(公告)号：US20230030648A1
公开(公告)日：2023-02-02
申请号：US17788687
申请日：2020-12-25
IPC分类号： C01F17/235 , C09K15/02 , C09K15/30 , C02F1/72
摘要： A cerium oxide nanoparticle is produced by mixing a solution of an aromatic heterocyclic compound having no substituent or at least one substituent selected from the group consisting of a methyl group, an ethyl group, an amino group, an aminomethyl group, a monomethylamino group, a dimethylamino group, and a cyano group and containing 2 to 8 carbon atoms and 1 to 4 nitrogen atoms in a ring structure of the aromatic heterocyclic compound, with a solution containing a cerium (III) ion or with a cerium (III) salt, followed by addition of an oxidant.
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公开(公告)号：US20230000906A1
公开(公告)日：2023-01-05
申请号：US17783678
申请日：2020-12-25
IPC分类号： A61K33/244 , A61K47/42 , B82Y30/00 , A61K9/10 , B82Y5/00
摘要： A dispersion solution contains a complex of cerium oxide nanoparticle with protein in which a hydrodynamic diameter and zeta potential of the protein are maintained. The dispersion solution is produced by mixing a solution containing the protein with a solution containing a cerium (III) ion or with a cerium (III) salt followed by adding an oxidizing agent thereto.
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公开(公告)号：US20240058452A1
公开(公告)日：2024-02-22
申请号：US17766660
申请日：2020-10-08
摘要： A pharmaceutical composition includes a drug and a temperature-responsive ionic liquid, wherein an anion in the temperature-responsive ionic liquid includes at least one selected from the group consisting of an aromatic carboxylate ion and an aromatic sulfonate ion, and is an anion represented by formula (I) and/or formula (II):
wherein, in formula (II), R1 represents a hydrogen atom or an acyl group and R2 represents an alkyl group optionally substituted with a halogen atom, a halogen atom or a sulfo group.-
公开(公告)号：US20220030857A1
公开(公告)日：2022-02-03
申请号：US17413714
申请日：2019-12-17
IPC分类号： A01N25/26 , C01F17/235 , C01F17/10 , C09K15/02 , C09K15/30 , A01P3/00 , A01N59/16 , A01P1/00
摘要： A cerium oxide nanoparticle whose surface is covered with a vinyl polymer has a heterocyclic amine skeleton such as piperazine, pyridine, imidazole, or carbazole or with a polyamide having a heterocyclic amine skeleton such as piperazine, pyridine, imidazole, or carbazole; and a decomposition method of a nucleic acid or a polypeptide by using the cerium oxide nanoparticle.
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公开(公告)号：US20160046774A1
公开(公告)日：2016-02-18
申请号：US14779214
申请日：2014-03-20
发明人： Shigeru Aoyama , Gouhei Yamamura , Takahiro Motoshiromizu , Masayuki Hirota , Risa Hamasaki , Masanori Sueoka
IPC分类号： C08J5/18
CPC分类号： C08J5/18 , C08J3/18 , C08J2300/16 , C08J2367/02 , C08J2367/04 , C08J2467/02 , C08J2471/02
摘要： A film is high in water resistance and degradability and formed mainly of biodegradable resin. The film includes a thermoplastic resin (A), and a filler (B) in an amount of 1 to 70 mass % of the total mass, i.e. 100 mass %, of the film, and having a porosity of 80% or less, a tear strength of 200 mN or less in a direction, and a tensile strength of less than 15 MPa in a direction.
摘要翻译： 膜的耐水性和降解性高，主要由生物降解性树脂形成。 该膜包括热塑性树脂（A）和填充剂（B），其量为总质量的1至70质量％，即100质量％的膜，并且具有80％或更小的孔隙率 方向的撕裂强度为200mN以下，拉伸强度小于15MPa。
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公开(公告)号：US11795449B2
公开(公告)日：2023-10-24
申请号：US17283624
申请日：2019-10-30
CPC分类号： C12N15/1006 , B01D15/206
摘要： This disclosure relates to a nucleic acid collection column that collects a nucleic acid from a liquid sample containing the nucleic acid. The nucleic acid collection column includes a sample injection portion having an opening into which the liquid sample containing the nucleic acid is injected, a support adsorption portion that houses a support for adsorbing the nucleic acid and in which the nucleic acid is adsorbed on the support, and a discharge portion that discharges a liquid passed through the support adsorption portion. The support includes aluminum oxide having a surface where a water-soluble neutral polymer is adsorbed. A space that houses the support in the support adsorption portion has a cylindrical shape, and has a volume of 0.13 μL or more and 13.5 μL or less. An aspect ratio (d1/d2) of the space satisfies 1.0≤d1/d2
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公开(公告)号：US20230240303A1
公开(公告)日：2023-08-03
申请号：US17927550
申请日：2021-05-24
摘要： A cerium oxide nanoparticle is produced by adding an oxidant to a solution comprising a boron compound represented by formula (I) and a cerium (III) ion:
BRn(OR′)3-n (I)
wherein n represents an integer of 0 to 2, R represents any of an alkyl group having 1 to 4 carbon atoms, a phenyl group, and a tolyl group, and R′ represents any of a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, a phenyl group, and a tolyl group, and when a plurality of Rs or of R's are present, the plurality of Rs or of R's are optionally the same or different.-
公开(公告)号：US20220090165A1
公开(公告)日：2022-03-24
申请号：US17287194
申请日：2019-10-21
IPC分类号： C12Q1/6806 , G01N30/14 , G01N30/88
摘要： A method of collecting a nucleic acid from a sample containing a nucleic acid using a support of aluminum oxide having a surface where a water-soluble neutral polymer is adsorbed, the method including steps a to c: step a: a step of bringing the support into contact with the sample containing a nucleic acid to adsorb the nucleic acid on the support; step b: a step of bringing the support on which the nucleic acid is adsorbed into contact with a solution A containing 1 mM or more and 40 mM or less of a chelating agent; and step c: after the step b, a step of bringing the support on which the nucleic acid is adsorbed into contact with a solution B containing 50 mM or more of a chelating agent to elute the nucleic acid.
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公开(公告)号：US11937598B2
公开(公告)日：2024-03-26
申请号：US17413714
申请日：2019-12-17
IPC分类号： A01N25/26 , A01N59/16 , A01P1/00 , A01P3/00 , C01F17/10 , C01F17/235 , C09K15/02 , C09K15/30
CPC分类号： A01N25/26 , A01N59/16 , A01P1/00 , A01P3/00 , C01F17/10 , C01F17/235 , C09K15/02 , C09K15/30
摘要： A cerium oxide nanoparticle whose surface is covered with a vinyl polymer has a heterocyclic amine skeleton such as piperazine, pyridine, imidazole, or carbazole or with a polyamide having a heterocyclic amine skeleton such as piperazine, pyridine, imidazole, or carbazole; and a decomposition method of a nucleic acid or a polypeptide by using the cerium oxide nanoparticle.
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公开(公告)号：US20210340522A1
公开(公告)日：2021-11-04
申请号：US17283624
申请日：2019-10-30
摘要： A nucleic acid collection column collects a nucleic acid from a liquid sample containing the nucleic acid. The nucleic acid collection column includes a sample injection portion having an opening into which the liquid sample containing the nucleic acid is injected, a support adsorption portion that houses a support for adsorbing the nucleic acid and in which the nucleic acid is adsorbed on the support, and a discharge portion that discharges a liquid passed through the support adsorption portion. The support includes aluminum oxide having a surface where a water-soluble neutral polymer is adsorbed. A space that houses the support in the support adsorption portion has a cylindrical shape, and has a volume of 0.13 μL or more and 13.5 μL or less. An aspect ratio (d1/d2) of the space satisfies 1.0≤d1/d2
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