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公开(公告)号:US09468381B2
公开(公告)日:2016-10-18
申请号:US13877979
申请日:2011-09-06
申请人: Toru Chiba , Yoshimi Obara , Makoto Hashizume , Takayuki Matsumoto , Kozo Konishi , Morimasa Tomikawa , Masaharu Murata
发明人: Toru Chiba , Yoshimi Obara , Makoto Hashizume , Takayuki Matsumoto , Kozo Konishi , Morimasa Tomikawa , Masaharu Murata
CPC分类号: A61B5/0084 , A61B1/0638 , A61B1/0646 , A61B5/0075 , A61B5/4238 , A61B5/4283 , G06T7/0012 , G06T2207/10024 , G06T2207/10068 , G06T2207/30092 , G06T2207/30096
摘要: A diagnostic system comprises a spectral image shooting means that shoots a spectral image within a predetermined wavelength range in a body cavity and obtains spectral image data, an image processing means that obtains the spectral image data and calculates an indicator indicating an area having a high possibility of a diseased portion from the spectral image data, and a monitor on which the indicator is displayed, and wherein the image processing means calculates, as the indicator, a ratio between an accumulated value of intensity values of all spectral images in the predetermined wavelength range and an intensity value of spectral images in a particular wavelength band, for each coordinate in the spectral image.
摘要翻译: 诊断系统包括:光谱图像拍摄装置,其在体腔内拍摄预定波长范围内的光谱图像并获得光谱图像数据;图像处理装置,其获得光谱图像数据,并计算指示具有高可能性的区域的指示符 从所述光谱图像数据得到的病变部分,以及显示所述指示符的监视器,并且其中,所述图像处理装置计算所述预定波长范围内的所有光谱图像的强度值的累加值之间的比率作为指标, 以及对于频谱图像中的每个坐标的特定波长带中的光谱图像的强度值。
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公开(公告)号:US20130197371A1
公开(公告)日:2013-08-01
申请号:US13877979
申请日:2011-09-06
申请人: Toru Chiba , Yoshimi Obara , Makoto Hashizume , Takayuki Matsumoto , Kozo Konishi , Morimasa Tomikawa , Masaharu Murata
发明人: Toru Chiba , Yoshimi Obara , Makoto Hashizume , Takayuki Matsumoto , Kozo Konishi , Morimasa Tomikawa , Masaharu Murata
IPC分类号: A61B5/00
CPC分类号: A61B5/0084 , A61B1/0638 , A61B1/0646 , A61B5/0075 , A61B5/4238 , A61B5/4283 , G06T7/0012 , G06T2207/10024 , G06T2207/10068 , G06T2207/30092 , G06T2207/30096
摘要: A diagnostic system comprises a spectral image shooting means that shoots a spectral image within a predetermined wavelength range in a body cavity and obtains spectral image data, an image processing means that obtains the spectral image data and calculates an indicator indicating an area having a high possibility of a diseased portion from the spectral image data, and a monitor on which the indicator is displayed, and wherein the image processing means calculates, as the indicator, a ratio between an accumulated value of intensity values of all spectral images in the predetermined wavelength range and an intensity value of spectral images in a particular wavelength band, for each coordinate in the spectral image.
摘要翻译: 诊断系统包括:光谱图像拍摄装置,其在体腔内拍摄预定波长范围内的光谱图像并获得光谱图像数据;图像处理装置,其获得光谱图像数据,并计算指示具有高可能性的区域的指示符 从所述光谱图像数据得到的病变部分,以及显示所述指示符的监视器,并且其中,所述图像处理装置计算所述预定波长范围内的所有光谱图像的强度值的累加值之间的比率作为指标, 以及对于频谱图像中的每个坐标的特定波长带中的光谱图像的强度值。
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公开(公告)号:US20140010424A1
公开(公告)日:2014-01-09
申请号:US14006775
申请日:2012-02-10
申请人: Toru Chiba , Makoto Hashizume , Takayuki Matsumoto , Kozo Konishi , Morimasa Tomikawa , Masaharu Murata , Tomohiko Akahoshi
发明人: Toru Chiba , Makoto Hashizume , Takayuki Matsumoto , Kozo Konishi , Morimasa Tomikawa , Masaharu Murata , Tomohiko Akahoshi
IPC分类号: A61B1/04
CPC分类号: A61B1/043 , A61B1/00009 , A61B1/0638 , A61B1/0646 , A61B5/0075 , A61B5/0084 , A61B5/14551 , A61B5/1459 , A61B5/4238 , G06T7/0012 , G06T2207/10024 , G06T2207/10068 , G06T2207/30092
摘要: A diagnostic system comprises: a spectral imaging means that captures a spectral image within a predetermined wavelength range in a body cavity and obtains spectral image data; an image processing means that receives the spectral image data, determines an index value indicating a region that is highly likely to be a lesion from the spectral image data, and generates and outputs an extracted lesion image based on the index value; and a monitor on which the extracted lesion image is displayed. The image processing means performs multiple regression analysis for each pixel of the spectral image with the spectral image data as a dependent variable and respective light absorption properties of oxyhemoglobin and deoxyhemoglobin as independent variables, and determines the index value based on respective concentrations of the oxyhemoglobin and the deoxyhemoglobin.
摘要翻译: 诊断系统包括:光谱成像装置,其捕获体腔内的预定波长范围内的光谱图像,并获得光谱图像数据; 接收所述光谱图像数据的图像处理装置,从所述光谱图像数据中确定表示高度可能为病变的区域的指标值,并且基于所述指标值生成并输出所提取的损伤图像; 以及显示提取的病变图像的监视器。 图像处理装置对光谱图像的每个像素执行多个回归分析,其中,将光谱图像数据作为因变量,并将氧合血红蛋白和脱氧血红蛋白的各自的光吸收特性作为独立变量,并且基于氧合血红蛋白的相应浓度和 脱氧血红蛋白。
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公开(公告)号:US09636426B2
公开(公告)日:2017-05-02
申请号:US14342879
申请日:2012-09-05
申请人: Hiroshi Maeda , Makoto Hashizume , Jun Fang , Hideaki Nakamura , Haibo Qin , Steffen Hackbarth , Masaharu Murata
发明人: Hiroshi Maeda , Makoto Hashizume , Jun Fang , Hideaki Nakamura , Haibo Qin , Steffen Hackbarth , Masaharu Murata
IPC分类号: A61Q5/12 , A61K49/00 , A61B1/04 , A61B1/313 , G01N33/574 , G01N33/58 , A61K41/00 , G01N21/33 , G01N21/64 , A61K47/48
CPC分类号: A61K49/0082 , A61B1/043 , A61B1/313 , A61K41/0057 , A61K41/0071 , A61K47/58 , A61K49/0017 , A61K49/0034 , A61K49/005 , A61K49/0054 , G01N21/33 , G01N21/6447 , G01N33/574 , G01N33/582 , G01N33/585
摘要: The present invention provides a fluorescent molecular probe for efficient fluorescent detection (visualization) of tumors or for implementing fluorescent detection and photodynamic treatment, more specifically, the present invention provides a macromolecular fluorescent molecular probe for fluorescent detection of tumor, comprising a complex comprising a fluorescent molecule and a biocompatibie macromolecule.
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公开(公告)号:US20140294735A1
公开(公告)日:2014-10-02
申请号:US14342879
申请日:2012-09-05
申请人: Hiroshi Maeda , Makoto Hashizume , Jun Fang , Hideaki Nakamura , Haibo Qin , Steffen Hackbarth , Masaharu Murata
发明人: Hiroshi Maeda , Makoto Hashizume , Jun Fang , Hideaki Nakamura , Haibo Qin , Steffen Hackbarth , Masaharu Murata
IPC分类号: A61K49/00
CPC分类号: A61K49/0082 , A61B1/043 , A61B1/313 , A61K41/0057 , A61K41/0071 , A61K47/58 , A61K49/0017 , A61K49/0034 , A61K49/005 , A61K49/0054 , G01N21/33 , G01N21/6447 , G01N33/574 , G01N33/582 , G01N33/585
摘要: The present invention provides a fluorescent molecular probe for efficient fluorescent detection (visualization) of tumors or for implementing fluorescent detection and photodynamic treatment, more specifically, the present invention provides a macromolecular fluorescent molecular probe for fluorescent detection of tumor, comprising a complex comprising a fluorescent molecule and a biocompatibie macromolecule.
摘要翻译: 本发明提供了一种用于有效荧光检测(可视化)肿瘤或用于实现荧光检测和光动力学治疗的荧光分子探针,更具体地,本发明提供了用于肿瘤荧光检测的大分子荧光分子探针,其包含荧光 分子和生物相容性大分子。
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