公开(公告)号：US20140306703A1

公开(公告)日：2014-10-16

申请号：US14240171

申请日：2012-07-27

申请人： Toru Shirai ,  Yoshitaka Bito ,  Satoshi Hirata ,  Yoshihisa Soutome

发明人： Toru Shirai ,  Yoshitaka Bito ,  Satoshi Hirata ,  Yoshihisa Soutome

IPC分类号： G01R33/46

CPC分类号： G01R33/4625 ,  A61B5/055 ,  G01R33/485 ,  G01R33/56518

摘要： An object of the present invention is to suppress artifacts generated by correction of spectral distortion induced by eddy currents in MRI devices with a simple method, and thereby improve accuracy of the correction. In the eddy current correction processing for correcting spectral distortion caused by an eddy current using phase values of FID signals of a substance showing higher signal intensities compared with a metabolite as an object of measurement, phase jumps of the phase values used for the correction are corrected beforehand. In the correction of the phase jumps, small phase change amount points are identified by using primary time differential values of the phase values, and the other points are identified as a phase jump generation region. Then, the primary time differential values corresponding to the identified phase jump generation regions are excluded. The phase jump generation regions are identified as regions where the primary time differential value changes in an amount not smaller than a threshold value defined beforehand within a range defined beforehand.

摘要翻译： 本发明的目的是通过简单的方法来抑制由MRI装置中的涡流引起的光谱失真校正而产生的伪影，从而提高校正精度。 在使用与作为测量对象的代谢物相比显示较高信号强度的物质的FID信号的相位值来校正由涡流引起的光谱失真的涡流校正处理中，校正用于校正的相位值的相位跳变 预先。 在相位跳变的校正中，通过使用相位值的一次时间差分值来识别小的相位变化量点，并且将其他点识别为相位跳跃产生区域。 然后，排除与所识别的相位跳跃发生区域对应的主要时间差值。 相位跳变产生区域被识别为主要时间差值在不小于预先定义的范围内预先定义的阈值的量的变化的区域。

公开(公告)号：US20130214785A1

公开(公告)日：2013-08-22

申请号：US13881739

申请日：2011-10-26

申请人： Toru Shirai ,  Yoshitaka Bito ,  Satoshi Hirata ,  Yoshihisa Soutome ,  Yo Taniguchi

发明人： Toru Shirai ,  Yoshitaka Bito ,  Satoshi Hirata ,  Yoshihisa Soutome ,  Yo Taniguchi

IPC分类号： G01R33/36

CPC分类号： G01R33/3621 ,  A61B5/055 ,  G01R33/465 ,  G01R33/4828 ,  G01R33/485 ,  G01R33/5611

摘要： Images of two or more kinds of substances showing different chemical shifts, such as water image and metabolite image, are obtained without extending measurement time. For example, images of two or more kinds of desired substances showing different chemical shifts, such as water image and metabolite image, are obtained by one time of execution of an imaging sequence. In this execution, a pre-pulse is applied so that signals of the substances to be separated shift on the image, and magnetic resonance signals are received with receiver RF coils in a number not smaller than the number of types of the substances to be separated. An image reconstructed from the magnetic resonance signals is separated into images of the individual substances using sensitivity maps of the receiver RF coils. Then, correction is performed for returning the shifted image to the original position. Further, residual signals induced by errors generated in the measurement and the separation processing are eliminated by using spectroscopic images obtained after the separation.

摘要翻译： 在不延长测量时间的情况下，获得显示不同化学位移的两种或更多种物质的图像，例如水图像和代谢物图像。 例如，通过一次执行成像序列，可以获得显示不同化学位移的两种或更多种所需物质的图像，例如水图像和代谢物图像。 在该执行中，施加预脉冲，使得要分离的物质的信号在图像上移动，并且用接收器RF线圈​​接收不少于待分离物质的数量的数量的磁共振信号 。 使用接收机RF线圈的灵敏度图将从磁共振信号重构的图像分离成各个物质的图像。 然后，执行用于将移动的图像返回到原始位置的校正。 此外，通过使用分离后获得的分光图像来消除由测量和分离处理中产生的误差引起的残留信号。

公开(公告)号：US09678187B2

公开(公告)日：2017-06-13

申请号：US14240171

申请日：2012-07-27

申请人： Toru Shirai ,  Yoshitaka Bito ,  Satoshi Hirata ,  Yoshihisa Soutome

发明人： Toru Shirai ,  Yoshitaka Bito ,  Satoshi Hirata ,  Yoshihisa Soutome

IPC分类号： G01R33/46 ,  G01R33/485 ,  G01R33/565 ,  A61B5/055

CPC分类号： G01R33/4625 ,  A61B5/055 ,  G01R33/485 ,  G01R33/56518

摘要： An object of the present invention is to suppress artifacts generated by correction of spectral distortion induced by eddy currents in MRI devices with a simple method, and thereby improve accuracy of the correction.

公开(公告)号：US09389289B2

公开(公告)日：2016-07-12

申请号：US13881739

申请日：2011-10-26

申请人： Toru Shirai ,  Yoshitaka Bito ,  Satoshi Hirata ,  Yoshihisa Soutome ,  Yo Taniguchi

发明人： Toru Shirai ,  Yoshitaka Bito ,  Satoshi Hirata ,  Yoshihisa Soutome ,  Yo Taniguchi

IPC分类号： G01R33/36 ,  A61B5/055 ,  G01R33/465 ,  G01R33/48 ,  G01R33/485 ,  G01R33/561

CPC分类号： G01R33/3621 ,  A61B5/055 ,  G01R33/465 ,  G01R33/4828 ,  G01R33/485 ,  G01R33/5611

摘要： Images of two or more kinds of substances showing different chemical shifts, such as water image and metabolite image, are obtained without extending measurement time. For example, images of two or more kinds of desired substances showing different chemical shifts, such as water image and metabolite image, are obtained by one time of execution of an imaging sequence. In this execution, a pre-pulse is applied so that signals of the substances to be separated shift on the image, and magnetic resonance signals are received with receiver RF coils in a number not smaller than the number of types of the substances to be separated. An image reconstructed from the magnetic resonance signals is separated into images of the individual substances using sensitivity maps of the receiver RF coils. Then, correction is performed for returning the shifted image to the original position. Further, residual signals induced by errors generated in the measurement and the separation processing are eliminated by using spectroscopic images obtained after the separation.

摘要翻译： 在不延长测量时间的情况下，获得显示不同化学位移的两种或更多种物质的图像，例如水图像和代谢物图像。 例如，通过一次执行成像序列，可以获得显示不同化学位移的两种或更多种所需物质的图像，例如水图像和代谢物图像。 在该执行中，施加预脉冲，使得要分离的物质的信号在图像上移动，并且用接收器RF线圈​​接收不少于待分离物质的数量的数量的磁共振信号 。 使用接收机RF线圈的灵敏度图将从磁共振信号重构的图像分离成各个物质的图像。 然后，执行用于将移动的图像返回到原始位置的校正。 此外，通过使用分离后获得的分光图像来消除由测量和分离处理中产生的误差引起的残留信号。

公开(公告)号：US08188739B2

公开(公告)日：2012-05-29

申请号：US12519197

申请日：2007-06-29

申请人： Toru Shirai ,  Yoshitaka Bito ,  Yo Taniguchi ,  Satoshi Hirata

发明人： Toru Shirai ,  Yoshitaka Bito ,  Yo Taniguchi ,  Satoshi Hirata

IPC分类号： G01V3/00

CPC分类号： G01R33/485 ,  G01R33/483 ,  G01R33/5602 ,  G01R33/5607

摘要： A method for obtaining the most appropriate amplitude of signal suppression pulse, which suppresses unnecessary signals from the substance not subjected to measurement, highly accurately, swiftly and stably, and an MRI apparatus that enables the optimization are provided.A pulse amplitude adjusting means equipped in the MRI apparatus acquires signals while changing the amplitude of signal suppression pulse and calculates signal absolute values and phase values, and computes reference signals, which are polarized signal absolute values, based on the changes in signal phase values. This reference signals are subjected to polynomial fitting. A value which makes this fitting curve is 0 or closes to 0 is set as the optimal pulse amplitude.

摘要翻译： 提供了一种用于获得信号抑制脉冲的最适当振幅的方法，其能够高度准确，快速且稳定地抑制不被测量的物质的不必要的信号，并且提供能够进行优化的MRI装置。 装备在MRI装置中的脉冲幅度调整装置在改变信号抑制脉冲的振幅的同时获取信号，并且计算信号绝对值和相位值，并且基于信号相位值的变化来计算作为极化信号绝对值的参考信号。 该参考信号经过多项式拟合。 使该拟合曲线为0或接近0的值被设定为最佳脉冲幅度。

公开(公告)号：US20080009703A1

公开(公告)日：2008-01-10

申请号：US11797878

申请日：2007-05-08

申请人： Yoshitaka Bito ,  Hisaaki Ochi ,  Yo Taniguchi ,  Satoshi Hirata ,  Toru Shirai

发明人： Yoshitaka Bito ,  Hisaaki Ochi ,  Yo Taniguchi ,  Satoshi Hirata ,  Toru Shirai

IPC分类号： A61B5/05

CPC分类号： G01R33/485 ,  G01R33/5608

摘要： A magnetic resonance imaging system capable of conducting spectroscopic imaging with an improved SNR without degrading the spatial resolution includes edge-preserving filter processing means for spectroscopic imaging. The edge-preserving filter processing means executes processing including the steps of calculating spectral similarity in spatial neighborhoods (spatially neighboring voxels) at each voxel in spectroscopic imaging data, calculating a spectral weight according to the spectral similarity, and conducting weighted smoothing for compounding spectra of spatial neighborhoods (spatially neighboring voxels) according to the spectral weight.

摘要翻译： 能够在不降低空间分辨率的情况下以改善的SNR进行光谱成像的磁共振成像系统包括用于分光成像的边缘保留滤波处理装置。 边缘保留滤波处理装置执行处理，其包括以下步骤：计算分光成像数据中的每个体素的空间邻域（空间相邻体素）中的频谱相似度，根据频谱相似度计算频谱权重，以及进行加权平滑化， 根据光谱权重的空间邻域（空间相邻体素）。

公开(公告)号：US20120049845A1

公开(公告)日：2012-03-01

申请号：US13140484

申请日：2010-02-03

申请人： Yoshitaka Bito ,  Satoshi Hirata ,  Hisaaki Ochi ,  Koji Hirata ,  Toru Shirai ,  Yosuke Otake

发明人： Yoshitaka Bito ,  Satoshi Hirata ,  Hisaaki Ochi ,  Koji Hirata ,  Toru Shirai ,  Yosuke Otake

IPC分类号： G01R33/32

CPC分类号： G01R33/485 ,  G01R33/56341

摘要： In the diffusion spectroscopic imaging, in which intensity of molecular diffusion is imaged with separating chemical substances, with suppressing artifacts resulting from object motion of an object, spatial resolution, spectral band and SNR are maintained, and measurement accuracy is enhanced. A measurement for acquiring diffusion SI data is repeated a plurality of times with changing acquisition timing, phase variation of each measurement result is corrected, and a diffusion SI image is reconstructed from the corrected measurement results. In addition, the phase variation is calculated for every point in the space from the diffusion SI data acquired by each measurement or navigation data obtained by each measurement. The phase correction is independently performed for every point in the space.

摘要翻译： 在通过分离化学物质成像分子扩散强度的扩散光谱成像中，通过抑制由物体的物体运动产生的伪影，保持了空间分辨率，光谱带和SNR，并且提高了测量精度。 通过改变获取定时多次重复获取扩散SI数据的测量，校正每个测量结果的相位变化，并从校正的测量结果重建扩散SI图像。 此外，根据通过各测量获得的扩散SI数据或通过每次测量获得的导航数据，计算空间中的每个点的相位变化。 对于空间中的每一个点都独立执行相位校正。

公开(公告)号：US20100097062A1

公开(公告)日：2010-04-22

申请号：US12519197

申请日：2007-06-29

申请人： Toru Shirai ,  Yoshitaka Bito ,  Yo Taniguchi ,  Satoshi Hirata

发明人： Toru Shirai ,  Yoshitaka Bito ,  Yo Taniguchi ,  Satoshi Hirata

IPC分类号： G01V3/14

CPC分类号： G01R33/485 ,  G01R33/483 ,  G01R33/5602 ,  G01R33/5607

摘要： A method for obtaining the most appropriate amplitude of signal suppression pulse, which suppresses unnecessary signals from the substance not subjected to measurement, highly accurately, swiftly and stably, and an MRI apparatus that enables the optimization are provided.A pulse amplitude adjusting means equipped in the MRI apparatus acquires signals while changing the amplitude of signal suppression pulse and calculates signal absolute values and phase values, and computes reference signals, which are polarized signal absolute values, based on the changes in signal phase values. This reference signals are subjected to polynomial fitting. A value which makes this fitting curve is 0 or closes to 0 is set as the optimal pulse amplitude.

摘要翻译： 提供了一种用于获得信号抑制脉冲的最适当振幅的方法，其能够高度准确，快速且稳定地抑制不被测量的物质的不必要的信号，并且提供能够进行优化的MRI装置。 装备在MRI装置中的脉冲幅度调整装置在改变信号抑制脉冲的振幅的同时获取信号，并且计算信号绝对值和相位值，并且基于信号相位值的变化来计算作为极化信号绝对值的参考信号。 该参考信号经过多项式拟合。 使该拟合曲线为0或接近0的值被设定为最佳脉冲幅度。

公开(公告)号：US20100272337A1

公开(公告)日：2010-10-28

申请号：US12741086

申请日：2008-07-07

申请人： Toru Shirai ,  Yoshitaka Bito ,  Yukari Yamamoto ,  Satoshi Hirata

发明人： Toru Shirai ,  Yoshitaka Bito ,  Yukari Yamamoto ,  Satoshi Hirata

IPC分类号： G06K9/00

CPC分类号： G01R33/56518 ,  G01R33/485 ,  G01R33/5618

摘要： While removing signals unnecessary for measuring signals from a metabolite, data required for eddy current correction are obtained in a short period of time. Signals from an unnecessary substance which is not an object of the measurement are removed, and phase data for correcting spectral distortion caused by an eddy current are obtained by a single measurement. Two kinds of frequency-selective pulses of which intensities are adjusted so that the signals from the unnecessary substance should have the same absolute values of intensities and opposite polarities are applied with changing intensities for every phase encoding for at least one axis, and the obtained signals are arranged in a k-space. By removing aliasing of image data obtained from the k-space data, signals from an unnecessary substance are removed, and phase data for eddy current correction are calculated by using a part of the k-space data.

摘要翻译： 在消除从代谢物测量信号所不必要的信号的同时，在短时间内获得涡流校正所需的数据。 除去不是测量对象的不必要物质的信号，并且通过单次测量获得用于校正由涡流引起的光谱失真的相位数据。 调整强度的两种频率选择脉冲，使得来自不需要的物质的信号应具有相同的强度绝对值和相反的极性，对于至少一个轴的每个相位编码的变化强度，并且获得的信号 被布置在k空间中。 通过去除从k空间数据获得的图像数据的混叠，去除来自不需要的物质的信号，并且通过使用k空间数据的一部分来计算用于涡流校正的相位数据。

公开(公告)号：US09097778B2

公开(公告)日：2015-08-04

申请号：US13140484

申请日：2010-02-03

申请人： Yoshitaka Bito ,  Satoshi Hirata ,  Hisaaki Ochi ,  Koji Hirata ,  Toru Shirai ,  Yosuke Otake

发明人： Yoshitaka Bito ,  Satoshi Hirata ,  Hisaaki Ochi ,  Koji Hirata ,  Toru Shirai ,  Yosuke Otake

IPC分类号： G01R33/485 ,  G01R33/563

CPC分类号： G01R33/485 ,  G01R33/56341

摘要： In the diffusion spectroscopic imaging, in which intensity of molecular diffusion is imaged with separating chemical substances, with suppressing artifacts resulting from object motion of an object, spatial resolution, spectral band and SNR are maintained, and measurement accuracy is enhanced. A measurement for acquiring diffusion SI data is repeated a plurality of times with changing acquisition timing, phase variation of each measurement result is corrected, and a diffusion SI image is reconstructed from the corrected measurement results. In addition, the phase variation is calculated for every point in the space from the diffusion SI data acquired by each measurement or navigation data obtained by each measurement. The phase correction is independently performed for every point in the space.

摘要翻译： 在通过分离化学物质成像分子扩散强度的扩散光谱成像中，通过抑制由物体的物体运动产生的伪影，保持了空间分辨率，光谱带和SNR，并且提高了测量精度。 通过改变获取定时多次重复获取扩散SI数据的测量，校正每个测量结果的相位变化，并从校正的测量结果重建扩散SI图像。 此外，根据通过各测量获得的扩散SI数据或通过每次测量获得的导航数据，计算空间中每个点的相位变化。 对于空间中的每一个点都独立执行相位校正。