公开(公告)号：US5136042A

公开(公告)日：1992-08-04

申请号：US465167

申请日：1990-02-01

申请人： Toshiaki Kuwatsuka ,  Seiichi Watanabe ,  Yoshinori Tanaka ,  Toshiyuki Kouno ,  Katsutoshi Ishikawa

发明人： Toshiaki Kuwatsuka ,  Seiichi Watanabe ,  Yoshinori Tanaka ,  Toshiyuki Kouno ,  Katsutoshi Ishikawa

IPC分类号： C07D277/56

CPC分类号： C07D277/56

摘要： Disclosed herein is a process for the preparation of a thiazolecarboxylic acid chloride represented by the following general formula (II): ##STR1## wherein R.sub.1 represents a hydrogen or halogen atom, a lower alkyl group, a lower alkoxy group, or a lower alkyl group substituted by a halogen atom or lower alkoxy group, and R.sub.2 represents a hydrogen atom, a lower alkyl group, or a lower alkyl group substituted by a halogen atom or lower alkoxy group, which comprises reacting a thiazolecarboxylic acid represented by the following general formula (I): ##STR2## wherein R.sub.1 and R.sub.2 have the same meanings as defined with respect to formula (II), with phosgene or trichloromethyl chloroformate in the presence or absence of a catalyst.

公开(公告)号：US5240951A

公开(公告)日：1993-08-31

申请号：US761217

申请日：1991-09-19

申请人： Hitoshi Shimotori ,  Yuji Yanase ,  Takeshi Sekino ,  Katsutoshi Ishikawa ,  Toshiaki Kuwatsuka ,  Hiroharu Tanikawa ,  Hideo Kawashima ,  Naofumi Tomura ,  Yoshiro Kanemoto

发明人： Hitoshi Shimotori ,  Yuji Yanase ,  Takeshi Sekino ,  Katsutoshi Ishikawa ,  Toshiaki Kuwatsuka ,  Hiroharu Tanikawa ,  Hideo Kawashima ,  Naofumi Tomura ,  Yoshiro Kanemoto

IPC分类号： A01N43/80 ,  C07D275/02 ,  C07D275/03

CPC分类号： C07D275/03 ,  A01N43/80

摘要： Application of a rice blast control agent containing an isothiazolecarboxylic acid derivative of the below-described formula, which shows excellent activity against rice blast (Pyricularia oryzae) in rice cultivation, to the water surface of a paddy rice field results in the absorption of the derivative through roots of rice plants, so that the resistance of the rice plants can be enhanced. ##STR1## wherein R.sup.1 and R.sup.2 independently mean a hydrogen or halogen atom or a particular group, and Y stands for an OR.sub.3 group (R.sup.3 being a hydrogen or alkali metal atom or a particular group), an NHR.sup.4 group (R.sup.4 being a hydrogen atom or a particular group), or a morpholino group.

摘要翻译： 在水稻栽培中将含有对稻瘟病稻瘟病（Pyricularia oryzae）具有优异活性的下述式的异噻唑羧酸衍生物的稻瘟病控制剂施用于水稻田的水面，导致衍生物的吸收 通过水稻根系，可以提高水稻的抗性。 其中R1和R2独立地表示氢或卤素原子或特定基团，Y表示OR3基团（R3表示氢或碱金属原子或特定基团），NHR4基团（R4表示氢原子 或特定组）或吗啉基。

公开(公告)号：US4814337A

公开(公告)日：1989-03-21

申请号：US38895

申请日：1987-04-16

申请人： Katsutoshi Ishikawa ,  Hitoshi Shimotori ,  Noboru Iida ,  Toshiaki Kuwatsuka ,  Junya Fujiwara ,  Yuji Yanase ,  Takeshi Sekino

发明人： Katsutoshi Ishikawa ,  Hitoshi Shimotori ,  Noboru Iida ,  Toshiaki Kuwatsuka ,  Junya Fujiwara ,  Yuji Yanase ,  Takeshi Sekino

IPC分类号： A01N25/30 ,  A01N43/54 ,  A01N47/40 ,  A01P3/00 ,  C07D239/38 ,  C07D239/24

CPC分类号： A01N43/54 ,  C07D239/38

摘要： Disclosed are dihalogenothiocyanopyrimidine derivatives of the general formula ##STR1## wherein X and Y are halogen atoms, a process for preparing such derivatives, as well as agricultural and horticultural fungicidal compositions containing such a derivative as active ingredient.

摘要翻译： 公开了通式为其中X和Y为卤素原子的二卤代硫代氰基嘧啶衍生物，制备该衍生物的方法，以及含有这种衍生物作为活性成分的农业和园艺杀真菌组合物。

公开(公告)号：US4980363A

公开(公告)日：1990-12-25

申请号：US259817

申请日：1988-10-19

申请人： Hitoshi Shimotori ,  Yoshiro Kanemoto ,  Hideo Yamazaki ,  Tsutomu Ishii ,  Shuji Ozawa ,  Yuji Yanase ,  Toshiaki Kuwatsuka ,  Yoshinori Tanaka ,  Takeshi Sekine ,  Keiko Shinada

发明人： Hitoshi Shimotori ,  Yoshiro Kanemoto ,  Hideo Yamazaki ,  Tsutomu Ishii ,  Shuji Ozawa ,  Yuji Yanase ,  Toshiaki Kuwatsuka ,  Yoshinori Tanaka ,  Takeshi Sekine ,  Keiko Shinada

IPC分类号： A01N43/74 ,  A01N43/78 ,  A01N43/80 ,  C07D275/02 ,  C07D275/03 ,  C07D277/56 ,  C07D417/12 ,  C07D521/00

CPC分类号： C07D275/03 ,  A01N43/74 ,  A01N43/78 ,  A01N43/80 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D277/56 ,  C07D417/12

摘要： An amide derivative represented by the following general formula (I) ##STR1## wherein one of X and Y represents a sulfur atom and the other represents a carbon atom, Z represents a nitrile or thioamide group, each of R.sup.1 and R.sup.2 represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 6 carbon atoms, a halomethyl group or a phenyl group, and R.sup.3 represents an alkenyl group having 2 to 6 carbon atoms, a haloalkenyl group having 2 to 4 carbon atoms, a furyl group, a thienyl group, an alkoxy group having 1 to 4 carbon atoms, an alkylthio group having 1 to 4 carbon atoms, an alkynyloxy group having 3 to 5 carbon atoms, an alkynylthio group having 3 to 5 carbon atoms, a pyrazolyl group, or an unsubstituted or halo-substituted phenyl group; processes for producing the amide derivative; an agricultural-horicultural fungicide comprising the amide derivative as an active ingredient; and to an agricultural-horicultural fungicidal composition comprising the amide derivative of general formula (I) as an active ingredient.

公开(公告)号：US5104886A

公开(公告)日：1992-04-14

申请号：US545026

申请日：1990-06-28

申请人： Hitoshi Shimotori ,  Yoshiro Kanemoto ,  Hideo Yamazaki ,  Tsutomu Ishii ,  Shuji Ozawa ,  Yuji Yanase ,  Toshiaki Kuwatsuka ,  Yoshinori Tanaka ,  Takeshi Sekine ,  Keiko Shinada

发明人： Hitoshi Shimotori ,  Yoshiro Kanemoto ,  Hideo Yamazaki ,  Tsutomu Ishii ,  Shuji Ozawa ,  Yuji Yanase ,  Toshiaki Kuwatsuka ,  Yoshinori Tanaka ,  Takeshi Sekine ,  Keiko Shinada

IPC分类号： A01N43/74 ,  A01N43/78 ,  A01N43/80 ,  C07D275/02 ,  C07D275/03 ,  C07D277/56 ,  C07D417/12 ,  C07D521/00

CPC分类号： C07D275/03 ,  A01N43/74 ,  A01N43/78 ,  A01N43/80 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D277/56 ,  C07D417/12

摘要： An amide derivative represented by the following general formula (I) ##STR1## wherein one of X and Y represents a sulfur atom and the other represents a carbon atom, Z represents a nitrile or thioamide group, each of R.sup.1 and R.sup.2 represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 6 carbon atoms, a halomethyl group or a phenyl group, and R.sup.3 represents an alkenyl group having 2 to 6 carbon atoms, a haloalkenyl group having 2 to 4 carbon atoms, a furyl group, a thienyl group, an alkoxy group having 1 to 4 carbon atoms, an alkylthio group having 1 to 4 carbon atoms, an alkynyloxy group having 3 to 5 carbon atoms, an alkynylthio group having 3 to 5 carbon atoms, a pyrazolyl group, or an unsubstituted or halo-substituted phenyl group;processes for producing the amide derivative; an agricultural-horticultural fungicide comprising the amide derivative as an active ingredient; and to an agricultural-horticultural fungicidal composition comprising the amide derivative of general formula (I) as an active ingredient.

公开(公告)号：US4792565A

公开(公告)日：1988-12-20

申请号：US38971

申请日：1987-04-16

申请人： Hitoshi Shimotori ,  Tutomu Ishii ,  Hideo Yamazaki ,  Toshiaki Kuwatsuka ,  Yuji Yanase ,  Yoshinori Tanaka

发明人： Hitoshi Shimotori ,  Tutomu Ishii ,  Hideo Yamazaki ,  Toshiaki Kuwatsuka ,  Yuji Yanase ,  Yoshinori Tanaka

IPC分类号： C07D231/12 ,  A01N25/02 ,  A01N43/56 ,  C07D231/14 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C07D231/16

CPC分类号： C07D403/12 ,  A01N43/56 ,  C07D231/14 ,  C07D405/12 ,  C07D409/12

摘要： Novel pyrazole derivatives of the general formula (I) ##STR1## wherein R.sup.1 represents an alkyl, haloalkyl, alkenyl, haloalkenyl or phenyl group, R.sup.2 and R.sup.3 each represent a hydrogen or halogen atom, or an alkyl, haloalkyl, alkoxy, alkoxyalkyl or phenyl group, and R.sup.4 represents an alkyl, alkenyl, haloalkenyl or phenyl group, or a heterocyclic aromatic group which contains at least one of oxygen, nitrogen and sulfur atoms and may be unsubstituted or substituted,which are useful as agricultural and horticultural fungicides. The pyrazole derivatives can be produced by reacting compounds of the general formula (III) ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are as defined above, and X represents a halogen atom,with aminoacetonitriles of the general formula (IV) ##STR3## wherein R.sup.4 is as defined above, or salts thereof.

摘要翻译： 通式（I）的新型吡唑衍生物其中R 1表示烷基，卤代烷基，烯基，卤代烯基或苯基，R 2和R 3各自表示氢或卤素原子，或烷基，卤代烷基，烷氧基， 烷氧基烷基或苯基，R4表示烷基，链烯基，卤代烯基或苯基，或含有氧，氮和硫原子中的至少一个的杂环芳基，可以是未取代或取代的，可用作农业和园艺杀真菌剂 。 吡唑衍生物可以通过使通式（III）的化合物（III）（其中R1，R2和R3如上定义，X​​代表卤素原子）与通式（IV）的氨基乙腈反应， （IV）其中R 4如上所定义，或其盐。

公开(公告)号：US5183927A

公开(公告)日：1993-02-02

申请号：US868577

申请日：1992-04-15

申请人： Atsushi Utsunomiya ,  Mitsuo Nakamura ,  Toshiaki Kuwatsuka ,  Yoshinori Tanaka

发明人： Atsushi Utsunomiya ,  Mitsuo Nakamura ,  Toshiaki Kuwatsuka ,  Yoshinori Tanaka

IPC分类号： C07C269/06 ,  C07C271/12 ,  C07C271/24

CPC分类号： C07C271/24 ,  C07C269/06 ,  C07C271/12 ,  C07C2101/14

摘要： In preparing an iodoalkynyl carbamate by iodinating an alkynyl carbamate with iodine monochloride in water or a solvent mixture composed of water and an organic solvent in the presence of a base, the iodoalkynyl carbamate can be obtained in a yield of as high as 96 to 98% by using the alkynyl carbamate in a concentration of 5 to 20% by weight, dissolving the iodine monochloride in an aqueous solution of hydrochloric acid or an aqueous solution of an alkali metal chloride (the amount of iodine monochloride used being within the range of 1.0 to 1.2 moles per mole of the alkynyl carbamate and the amount of base used being within the range of 0.95 to 2.00 gram equivalents per mole of iodine monochloride), and carrying out the reaction at a temperature of 10.degree. to 40.degree. C. for a period of 1 to 4 hours.According to this process, highly pure iodoalkynyl carbamates which are useful as industrial germicides can be prepared with good selectivity and in high yield.

公开(公告)号：US06710151B2

公开(公告)日：2004-03-23

申请号：US10275901

申请日：2002-11-12

申请人： Toshiaki Kuwatsuka ,  Hideaki Ogata ,  Manabu Shimoda ,  Ryuuji Haseyama ,  Izumi Mega

发明人： Toshiaki Kuwatsuka ,  Hideaki Ogata ,  Manabu Shimoda ,  Ryuuji Haseyama ,  Izumi Mega

IPC分类号： C08G1879

CPC分类号： C08G18/79 ,  C08G18/7887 ,  C08G18/8016 ,  C08G18/8064 ,  C08G2150/20

摘要： The end-blocked isocyanate prepolymer having an oxadiazine ring according to the present invention is characterized in that at least one of isocyanate groups of a NCO-terminated isocyanate prepolymer, which has NCO groups at the ends and comprises units derived from an oxadiazinetrione compound (A) represented by the following formula (1) and units derived from an active hydrogen compound (B) represented by the following formula (2), is blocked with a unit derived from an end-blocking agent (C) having at least one active hydrogen in one molecule, and that the end-blocked isocyanate prepolymer has a softening point of not lower than 50° C., wherein R1 is a group selected from the group consisting of an aliphatic hydrocarbon group of 2 to 20 carbon atoms, an aliphatic hydrocarbon group having an aromatic group and an alicyclic hydrocarbon group, and n is an integer of 1 or greater, H—A—R2—A—H  (2) wherein R2 is a straight-chain, branched or cyclic alkylene group of 2 to 12 carbon atoms, and A is any one of an oxygen atom, a sulfur atom, a N—R′ group (R′ is a hydrogen atom, an alkyl group, an aryl group or an aralkyl group) and a COO group.

摘要翻译： 根据本发明的具有恶二嗪环的封端异氰酸酯预聚物的特征在于，末端具有NCO基团的NCO封端的异氰酸酯预聚物的异氰酸酯基团中的至少一个并且包含衍生自恶二嗪三酮化合物（A ）和由下式（2）表示的活性氢化合物（B）衍生的单元被源自具有至少一个活性氢的封端剂（C）的单元封闭 并且封端的异氰酸酯预聚物的软化点不低于50℃，其中R 1是选自2至20个碳原子的脂族烃基，脂族烃 具有芳基和脂环族烃基的基团，n为1以上的整数，其中，R 2为2〜12个碳原子的直链状，支链状或环状的亚烷基，A为任意的 的氧原子，硫原子，N-R'基（R'是氢原子，烷基，芳基或芳烷基）和COO基。