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    Polyethylene film for packaging
    1.
    发明授权
    Polyethylene film for packaging 有权
    聚乙烯薄膜包装

    公开(公告)号：US06426384B1

    公开(公告)日：2002-07-30

    申请号：US09744076

    申请日：2001-01-19

    申请人： Toshihiro Nishimura ,  Hiroshi Inoue ,  Michio Takeuchi

    发明人： Toshihiro Nishimura ,  Hiroshi Inoue ,  Michio Takeuchi

    IPC分类号： C08L2300

    CPC分类号： C08L23/06 ,  C08L23/0815 ,  C08L2205/02 ,  C08L2314/06 ,  C08L2666/04

    摘要： The polyethylene film of the present invention is excellent in tear resistance, impact resistance and transparency. The film of the invention is a polyethylene film suitable for packaging formed from a resin composition comprising a low-density polyethylene (A) having specific ranges of the density, melt flow rate and molecular weight distribution(Mw/Mn), and having (i) a thickness of 10 to 30 &mgr;m, (ii) Elmendorf tear strength of at least 20 kg/cm in the longitudinal direction, (iii) dart impact strength of at least 50 g, and (iv) HAZE value of not greater than 8%.

    摘要翻译： 本发明的聚乙烯薄膜的抗撕裂性，耐冲击性和透明性优异。 本发明的薄膜是适用于由包含密度，熔体流动速率和分子量分布（Mw / Mn）特定范围的低密度聚乙烯（A）的树脂组合物形成的包装形成的聚乙烯薄膜，并具有（i ），厚度为10〜30μm，（ii）沿长度方向至少20kg / cm的埃尔门多夫撕裂强度，（iii）落镖冲击强度至少为50g，（iv）HAZE值不大于8 ％。

    Resin compostion and stretched film obtained by using the same
    2.
    发明申请
    Resin compostion and stretched film obtained by using the same 有权
    通过使用它们获得的树脂组合物和拉伸膜

    公开(公告)号：US20070032601A1

    公开(公告)日：2007-02-08

    申请号：US10572385

    申请日：2004-09-17

    申请人： Tsutomu Tasaki ,  Toshihiro Nishimura ,  Hiroshi Inoue

    发明人： Tsutomu Tasaki ,  Toshihiro Nishimura ,  Hiroshi Inoue

    IPC分类号： C08L23/04

    CPC分类号： C08J5/18 ,  C08J2323/06 ,  C08J2323/08 ,  Y10S428/91 ,  Y10T428/31855 ,  Y10T428/31938

    摘要： The present invention relates to a polyethylene-based stretched film having excellent Elmendorf tear strength and uniform stretchability. The invention relates to a polyethylene-based stretched film which is obtained by stretching a polyethylene-based resin, wherein (A-i) Em and Et, which represent the values of Elmendorf tear strength in the MD and TD directions, respectively, as measured in accordance with ASTM D1922, satisfy the following formulas 1, 2 and 3: 20≦Em[N/m]≦3000  (Formula 1) 20≦Et[N/m]≦3000  (Formula 2) 0.1≦(Em/Et)≦3  (Formula 3); (a-ii) the tensile initial modulus TM in the MD direction satisfies the following formula 4: 300≦TM[MPa]≦10000  (Formula 4); and (a-iii) the thickness is in the range of 5 to 150 μm, and is excellent in the stretch uniformity.

    摘要翻译： 本发明涉及具有优异的埃尔门多夫撕裂强度和均匀拉伸性的聚乙烯基拉伸膜。 本发明涉及通过拉伸聚乙烯类树脂而获得的聚乙烯基拉伸膜，其中（Ai）Em和Et分别代表根据MD和TD方向的埃尔曼多夫撕裂强度值 与ASTM D1922相符合下列公式1,2和3：<？in-line-formula description =“In-line formula”end =“lead”？> 20 <= Em [N / m] <= 3000 1）<？in-line-formula description =“In-line Formulas”end =“tail”？> <？in-line-formula description =“In-line formula”end =“lead”？> 20 <= Et [N / m] <= 3000（公式2）<？in-line-formula description =“In-line Formulas”end =“tail”？> <？in-line-formula description =“In-line Formulas”end =“铅”？> 0.1 <=（Em / Et）<= 3（式3）; （a-ii）MD方向上的拉伸初始模量TM满足下列公式4：<？在线公式描述=“直线公式”end =“tail” =“在线公式”end =“lead”？> 300 <= TM [MPa] <= 10000（公式4）; <？in-line-formula description =“In-line Formulas”end =“tail”？>和（a-iii）厚度在5至150μm的范围内，并且拉伸均匀性优异。

    Resin composition and stretched film obtained by using the same
    3.
    发明授权
    Resin composition and stretched film obtained by using the same 有权
    树脂组合物和通过使用其获得的拉伸膜

    公开(公告)号：US07722961B2

    公开(公告)日：2010-05-25

    申请号：US10572385

    申请日：2004-09-17

    申请人： Tsutomu Tasaki ,  Toshihiro Nishimura ,  Hiroshi Inoue

    发明人： Tsutomu Tasaki ,  Toshihiro Nishimura ,  Hiroshi Inoue

    IPC分类号： B32B27/32 ,  C08L23/00 ,  C08L23/08

    CPC分类号： C08J5/18 ,  C08J2323/06 ,  C08J2323/08 ,  Y10S428/91 ,  Y10T428/31855 ,  Y10T428/31938

    摘要： A polyethylene-based stretched film with a thickness in the range of 10 to 100 μm, the film comprising components (A) and (B) (the total amount of components (A) and (B) being 100 parts by weight), and has a density in the range of 898 to 960 Kg/m3: (A) 50 to 95 parts by weight of a polyethylene composition which comprises the following components (I) and (II) (the total amount of (I) and (II) being 100 parts by weight), and has a density in the range of 890 to 940 Kg/m3: (I) 5 to 95 parts by weight of an ethylene/alpha-olefin copolymer obtained by copolymerization of ethylene and an alpha-olefin having 4 to 12 carbon atoms with the use of a metallocene catalyst, which has a melt flow rate in the range of 0.01 to 10 g/10 min and a density in the range of 900 to 925 Kg/m3, and, (II) 5 to 95 parts by weight of an ethylene/alpha-olefin copolymer obtained by copolymerization of ethylene and an alpha-olefin having 4 to 12 carbon atoms with the use of a metallocene catalyst, which has melt flow rate in the range of 1 to 100 g/10 min and a density in the range of 926 to 960 Kg/m3; and (B) 5 to 50 parts by weight of a high-pressure low density polyethylene which has a melt flow rate in the range of 0.1 to 10 g/10 min, and a density in the range of 910 to 930 Kg/m3.

    摘要翻译： 厚度为10〜100μm的聚乙烯系拉伸膜，由（A）成分和（B）成分（成分（A）和（B）的总量）为100重量份构成的膜） 具有898至960Kg / m 3范围内的密度：（A）50至95重量份的包含以下组分（I）和（II）（（I）和（II）的总量）的聚乙烯组合物 ）为100重量份，密度为890〜940Kg / m 3：（I）5〜95重量份通过乙烯与α-烯烃的共聚得到的乙烯/α-烯烃共聚物 具有4〜12个碳原子的金属茂催化剂，其熔体流动速率为0.01〜10g / 10min，密度为900〜925Kg / m 3，（II） 通过使用茂金属催化剂通过乙烯和具有4至12个碳原子的α-烯烃共聚得到的乙烯/α-烯烃共聚物5至95重量份，其熔体 流量范围为1〜100g / 10min，密度为926〜960kg / m3; 和（B）5至50重量份的熔体流动速率在0.1至10g / 10分钟范围内，密度在910至930kg / m 3范围内的高压低密度聚乙烯。

    Bag for packaging heavy materials
    4.
    发明授权
    Bag for packaging heavy materials 失效
    袋包装重物料

    公开(公告)号：US5609930A

    公开(公告)日：1997-03-11

    申请号：US418376

    申请日：1995-04-07

    申请人： Takashi Matsunaga ,  Toshihiro Nishimura ,  Hiroshi Inoue

    发明人： Takashi Matsunaga ,  Toshihiro Nishimura ,  Hiroshi Inoue

    IPC分类号： B32B27/20 ,  B32B27/32 ,  B65D33/02

    CPC分类号： B32B27/32 ,  Y10T428/1334 ,  Y10T428/1352 ,  Y10T428/24372 ,  Y10T428/24942 ,  Y10T428/2495 ,  Y10T428/24975 ,  Y10T428/258 ,  Y10T428/259 ,  Y10T428/31913

    摘要： A bag for packaging heavy materials, exhibiting excellent strength, content packaging performance, stacking performance on the pallets, and anti-collapsing performance. The bag is made of a multi-layer laminated film which comprises an outermost layer of a polyethylene film containing an inorganic filler in an amount of from 20 to 80% by weight and an innermost layer of a polyethylene film containing an inorganic filler in an amount of from 10 to 40% by weight, the outermost layer having on the surface thereof a coefficient of static friction of not smaller than 0.5 (ASTM D 1894), a coefficient of dynamic friction of not larger than 0.5 (ASTM D 1894) and a gloss of not larger than 50% (JIS Z 8741, at a measuring angle of 60.degree.), and the content of the inorganic filler in the innermost layer being from 1/2 to 1/6 of the content of the inorganic filler in the outermost layer.

    摘要翻译： 用于包装重材料的袋子，具有优异的强度，包装性能，托盘上的堆叠性能以及抗折叠性能。 该袋由多层层压膜制成，该多层层压膜包括含有20至80重量％的无机填料的聚乙烯膜的最外层，并且含有一定量的无机填料的聚乙烯膜的最内层 为10〜40重量％，最外层的表面的静摩擦系数为0.5以上（ASTM D 1894），动摩擦系数为0.5以下（ASTM D 1894）和 光泽度不大于50％（JIS Z 8741，测量角度为60度），最内层的无机填料的含量为+ E，fra 1/2 + EE至+ E， 6 + EE的最外层无机填料的含量。

    Liner film for bulk container and container liner
    6.
    发明授权
    Liner film for bulk container and container liner 失效
    散装集装箱和集装箱内衬的衬板

    公开(公告)号：US06194533B1

    公开(公告)日：2001-02-27

    申请号：US09049909

    申请日：1998-03-30

    申请人： Toshihiro Nishimura ,  Hiroshi Inoue ,  Yoichiro Tsuji ,  Takashi Hiraoka

    发明人： Toshihiro Nishimura ,  Hiroshi Inoue ,  Yoichiro Tsuji ,  Takashi Hiraoka

    IPC分类号： C08F21016

    CPC分类号： C08J5/18 ,  B65D90/046 ,  B65D2590/046 ,  C08J2323/08 ,  Y10S493/934

    摘要： Disclosed is a liner film for bulk container, which comprises a polyethylene (A) prepared by the use of a single site olefin polymerization catalyst such as a metallocene catalyst, said polyethylene (A) having a density of 0.920 to 0.940 g/cm3, MFR of 0.1 to 3.0 g/10 min and a melting point of 115 to 135° C. When the film is heat-sealed, its sealed portion preferably has a tensile strength at break (Ts) of 2.0 to 4.0 kg/15 mm and a tensile elongation at break (EL) of 150 to 600%. The liner film for bulk container has the advantages: the film can be made lightweight by decreasing the film thickness; the film shows such a high heat-sealing strength that the heat-sealed portion is not broken even if no adhesive tape is attached thereto; and a bulk container liner formed from the film can be filled with a content of a higher temperature than the conventional temperature. Also disclosed is a bulk container liner shaping the above film into a bag.

    摘要翻译： 公开了一种用于散装容器的衬里膜，其包括通过使用单位点烯烃聚合催化剂如茂金属催化剂制备的聚乙烯（A），所述聚乙烯（A）的密度为0.920至0.940g / cm3，MFR 为0.1〜3.0g / 10分钟，熔点为115〜135℃。当热封时，其密封部分的断裂强度（Ts）优选为2.0〜4.0kg / 15mm， 拉伸断裂伸长率（EL）为150〜600％。 用于散装容器的衬里膜具有以下优点：通过减小膜厚可以使膜重量轻; 该膜显示出如此高的热封强度，即使没有粘合带也不会损坏热密封部分; 并且由膜形成的散装容器衬垫可以填充比常规温度更高的温度的内容物。 还公开了将上述胶片成型为袋子的散装容器衬里。

    GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND USE THEREOF IN MEDICINES
    8.
    发明申请
    GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND USE THEREOF IN MEDICINES 有权
    葡萄糖醛酰氧基吡唑衍生物及其在药物中的应用

    公开(公告)号：US20090093419A1

    公开(公告)日：2009-04-09

    申请号：US12169882

    申请日：2008-07-09

    申请人： Hideki Fujikura ,  Nobuhiko Fushimi ,  Toshihiro Nishimura ,  Takeshi Nakabayashi ,  Masayuki Isaji

    发明人： Hideki Fujikura ,  Nobuhiko Fushimi ,  Toshihiro Nishimura ,  Takeshi Nakabayashi ,  Masayuki Isaji

    IPC分类号： A61K31/7056

    CPC分类号： A61K45/06 ,  A61K31/7056 ,  C07H17/02 ,  A61K2300/00

    摘要： The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: wherein R represents a hydrogen atom, a lower alkyl group or a group forming a prodrug; one of Q and T represents a group represented by the general formula: (wherein P represents a hydrogen atom or a group forming a prodrug), while the other represents a lower alkyl group or a halo(lower alkyl) group; R2 represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a halo(lower alkyl) group or a halogen atom; and with the proviso that P does not represent a hydrogen atom when R represents a hydrogen atom or a lower alkyl group, or pharmaceutically acceptable salts thereof, which exert an inhibitory activity in human SGLT2 and have an improved oral absorption, and therefore are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, diabetic complications or obesity, and pharmaceutically acceptable salts thereof, and pharmaceutical uses thereof.

    摘要翻译： 本发明提供由以下通式表示的吡喃葡萄糖氧吡唑衍生物：其中R表示氢原子，低级烷基或形成前药的基团; Q和T之一表示由通式表示的基团：（其中P表示氢原子或形成前药的基团），而另一个表示低级烷基或卤代（低级烷基）基团; R2表示氢原子，低级烷基，低级烷氧基，低级烷硫基，卤代（低级烷基）或卤素原子; 并且条件是当R表示氢原子或低级烷基时，P不表示氢原子，或其药学上可接受的盐，其在人SGLT2中具有抑制活性并具有改善的口服吸收，因此可用作 用于预防或治疗与高血糖相关的疾病如糖尿病，糖尿病并发症或肥胖症的药剂及其药学上可接受的盐及其药学用途。

    Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof
    9.
    发明授权
    Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof 失效
    吡喃葡萄糖氧基苄基苯衍生物，含有它们的药物组合物及其制备中间体

    公开(公告)号：US07053060B2

    公开(公告)日：2006-05-30

    申请号：US10432905

    申请日：2001-11-20

    申请人： Hideki Fujikura ,  Toshihiro Nishimura ,  Nobuhiko Fushimi ,  Kazuya Tatani ,  Norihiko Kikuchi ,  Kenji Katsuno ,  Masayuki Isaji

    发明人： Hideki Fujikura ,  Toshihiro Nishimura ,  Nobuhiko Fushimi ,  Kazuya Tatani ,  Norihiko Kikuchi ,  Kenji Katsuno ,  Masayuki Isaji

    IPC分类号： A01N43/04 ,  A61K31/70 ,  C07H15/00 ,  C07H17/00

    CPC分类号： C07H15/203

    摘要： The present invention relates to glucopyranosyloxybenzylbenzene derivatives represented by the general formula: wherein R1 represents a hydrogen atom, a hydroxy group, a substituted or unsubstituted amino group, a carbamoyl group, a substituted or unsubstituted (lower alkyl) group, a substituted or unsubstituted (lower alkoxy) group etc.; R2 represents a hydrogen atom or a lower alkyl group; and R3 represents a substituted or unsubstituted (lower alkyl) group, a substituted or unsubstituted (lower alkoxy) group, a substituted or unsubstituted (lower alkylthio) group etc., or pharmaceutically acceptable salts thereof, which have an inhibitory activity in human SGLT2 and are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, diabetic complication or obesity, pharmaceutical compositions comprising the same and intermediates thereof.

    摘要翻译： 本发明涉及由以下通式表示的吡喃葡萄糖氧基苄基苯衍生物：其中R 1表示氢原子，羟基，取代或未取代的氨基，氨基甲酰基，取代或未取代的（低级烷基 ）基团，取代或未取代的（低级烷氧基）基团等; R 2表示氢原子或低级烷基; 和R 3表示取代或未取代的（低级烷基）基团，取代或未取代的（低级烷氧基）基团，取代或未取代的（低级烷硫基）等，或其药学上可接受的盐，其中 在人SGLT2中具有抑制活性，并且可用作预防或治疗与高血糖相关的疾病如糖尿病，糖尿病并发症或肥胖症的药剂，包含其的药物组合物及其中间体。

    Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof
    10.
    发明申请
    Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof 失效
    吡喃葡萄糖氧基苄基苯衍生物，含有它们的药物组合物及其制备中间体

    公开(公告)号：US20050059614A1

    公开(公告)日：2005-03-17

    申请号：US10978413

    申请日：2004-11-02

    申请人： Hideki Fujikura ,  Toshihiro Nishimura ,  Nobuhiko Fushimi ,  Kazuya Tatani ,  Norihiko Kikuchi ,  Kenji Katsuno ,  Masayuki Isaji

    发明人： Hideki Fujikura ,  Toshihiro Nishimura ,  Nobuhiko Fushimi ,  Kazuya Tatani ,  Norihiko Kikuchi ,  Kenji Katsuno ,  Masayuki Isaji

    IPC分类号： A61P3/04 ,  A61P3/10 ,  A61P43/00 ,  C07H15/203 ,  A61K31/70 ,  C07H5/04 ,  C07H5/06

    CPC分类号： C07H15/203

    摘要： The present invention relates to glucopyranosyl-oxybenzylbenzene derivatives represented by the general formula: wherein R1 represents a hydrogen atom, a hydroxy group, a substituted or unsubstituted amino group, a carbamoyl group, a substituted or unsubstituted(lower alkyl) group, a substituted or unsubstituted(lower alkoxy) group etc.; R2 represents a hydrogen atom or a lower alkyl group; and R3 represents a substituted or unsubstituted(lower alkyl) group, a substituted or unsubstituted(lower alkoxy) group, a substituted or unsubstituted(lower alkylthio) group etc., or pharmaceutically acceptable salts thereof, which have an inhibitory activity in human SGLT2 and are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, diabetic complication or obesity, pharmaceutical compositions comprising the same and intermediates thereof.

    摘要翻译： 本发明涉及由以下通式表示的吡喃葡萄糖基 - 氧苄基苯衍生物：其中R 1表示氢原子，羟基，取代或未取代的氨基，氨基甲酰基，取代或未取代的（低级烷基） 取代或未取代的（低级烷氧基）等。 R 2表示氢原子或低级烷基; 和R 3表示具有抑制活性的取代或未取代的（低级烷基）基团，取代或未取代的（低级烷氧基）基团，取代或未取代的（低级烷硫基）等，或其药学上可接受的盐 人SGLT2，并且可用作预防或治疗与高血糖相关的疾病（如糖尿病，糖尿病并发症或肥胖症）的药剂，包含其的药物组合物及其中间体。