Method of judging inflammatory disease
    2.
    发明授权
    Method of judging inflammatory disease 失效
    炎症性疾病的诊断方法

    公开(公告)号:US07754422B2

    公开(公告)日:2010-07-13

    申请号:US10523723

    申请日:2003-08-08

    IPC分类号: C12Q1/68

    摘要: The object of the present invention is to determine inflammatory diseases such as myocardial infarction by identifying single nucleotide polymorphisms (SNPs) associated with myocardial infarction and utilizing these SNPs. The present invention provides a method for determining an inflammatory disease, which comprises detecting at least one gene polymorphism existing in at least one gene selected from the group consisting of a lymphotoxin-α (LT-α) gene, an I Kappa B-like (IKBL) gene, and a BAT1 gene; an oligonucleotide used in said method; a kit for diagnosing an inflammatory disease which comprises said oligonucleotide; and use thereof. The present invention further provides a method for treating an inflammatory disease; and a method for screening for a therapeutic agent for an inflammatory disease.

    摘要翻译: 本发明的目的是通过鉴定与心肌梗塞相关的单核苷酸多态性(SNP)和利用这些SNP来确定诸如心肌梗死的炎性疾病。 本发明提供了一种测定炎性疾病的方法,该方法包括检测至少一种存在于选自淋巴毒素-α(LT-α)基因,IκB样(LT-α) IKBL)基因和BAT1基因; 所述方法中使用的寡核苷酸; 用于诊断包含所述寡核苷酸的炎性疾病的试剂盒; 及其用途。 本发明还提供一种治疗炎性疾病的方法; 以及筛选炎性疾病治疗剂的方法。

    Method of judging inflammatory disease
    3.
    发明申请
    Method of judging inflammatory disease 失效
    炎症性疾病的诊断方法

    公开(公告)号:US20060147920A1

    公开(公告)日:2006-07-06

    申请号:US10523723

    申请日:2003-08-08

    IPC分类号: C12Q1/68

    摘要: The object of the present invention is to determine inflammatory diseases such as myocardial infarction by identifying single nucleotide polymorphisms (SNPs) associated with myocardial infarction and utilizing these SNPs. The present invention provides a method for determining an inflammatory disease, which comprises detecting at least one gene polymorphism existing in at least one gene selected from the group consisting of a lymphotoxin-α (LT-α) gene, an I Kappa B-like (IKBL) gene, and a BAT1 gene; an oligonucleotide used in said method; a kit for diagnosing an inflammatory disease which comprises said oligonucleotide; and use thereof. The present invention further provides a method for treating an inflammatory disease; and a method for screening for a therapeutic agent for an inflammatory disease.

    摘要翻译: 本发明的目的是通过鉴定与心肌梗塞相关的单核苷酸多态性(SNPs)和利用这些SNP来确定诸如心肌梗死的炎性疾病。 本发明提供了一种测定炎症性疾病的方法,该方法包括检测存在于选自淋巴毒素-α(LT-α)基因,IκB样(LT-α) IKBL)基因和BAT1基因; 所述方法中使用的寡核苷酸; 用于诊断包含所述寡核苷酸的炎性疾病的试剂盒; 及其用途。 本发明还提供一种治疗炎性疾病的方法; 以及筛选炎性疾病治疗剂的方法。