ORAL PREPARATION FOR PROMOTING SYNTHESIS OF TISSUE COLLAGEN
    1.
    发明申请
    ORAL PREPARATION FOR PROMOTING SYNTHESIS OF TISSUE COLLAGEN 审中-公开
    促进组织胶原合成的口服制剂

    公开(公告)号:US20090062371A1

    公开(公告)日:2009-03-05

    申请号:US12280846

    申请日:2007-03-23

    IPC分类号: A61K31/4015 A61P17/02

    摘要: An object of the present invention is to provide an oral preparation for promoting synthesis of tissue collagen, an oral preparation for promoting healing of skin wounds or an oral preparation for preventing or improving skin wrinkles or sagging, which is safe and has an excellent effect. The present invention can provide an oral preparation for promoting synthesis of tissue collagen, an oral preparation for promoting healing of skin wounds or an oral preparation for preventing or improving skin wrinkles or sagging, which comprises hydroxyproline or a salt thereof as an active ingredient.

    摘要翻译: 本发明的目的是提供促进组织胶原合成的口服制剂,用于促进皮肤伤口愈合的口服制剂或用于预防或改善皮肤皱纹或下垂的口服制剂,其是安全的并且具有优异的效果。 本发明可以提供一种用于促进组织胶原的口服制剂,用于促进皮肤伤口愈合的口服制剂或用于预防或改善皮肤皱纹或下垂的口服制剂,其包括羟脯氨酸或其盐作为活性成分。

    METHOD OF PREVENTING OR AMELIORATING PSORIASIS USING PYRROLOQUINOLINE QUINONE COMPOUNDS
    4.
    发明申请
    METHOD OF PREVENTING OR AMELIORATING PSORIASIS USING PYRROLOQUINOLINE QUINONE COMPOUNDS 有权
    使用吡咯啉喹啉化合物防止或增强PSORIASIS的方法

    公开(公告)号:US20100261749A1

    公开(公告)日:2010-10-14

    申请号:US12742351

    申请日:2008-11-12

    IPC分类号: A61K31/475 A61P17/06

    CPC分类号: C07D471/04

    摘要: It is an object of the present invention to provide a safe and highly effective preventing or ameliorating agent for skin psoriasis.The present invention provides a preventing or ameliorating agent for skin psoriasis, containing, as an active ingredient, a compound represented by general formula (I) or a salt thereof: (wherein R1, R2, and R3 simultaneously or separately represent a lower alkyl, lower alkenyl, lower alkynyl, aralkyl, araryl, or phenyl group, or a hydrogen atom).

    摘要翻译: 本发明的目的是提供一种安全且高效的防止或改善皮肤银屑病的药剂。 本发明提供一种皮肤银屑病的预防或改善剂,其含有通式(I)所示的化合物或其盐作为有效成分:(其中R1,R2和R3同时或分别表示低级烷基, 低级烯基,低级炔基,芳烷基,芳芳基或苯基,或氢原子)。

    Hair-growing agent
    6.
    发明授权
    Hair-growing agent 失效
    发丝剂

    公开(公告)号:US07015209B2

    公开(公告)日:2006-03-21

    申请号:US10895322

    申请日:2004-07-21

    IPC分类号: A61K31/66

    摘要: A hair-growing agent comprising, as active ingredients, one or more members selected from the group consisting of lysophosphatidic acids, and phosphatidic acids wherein the fatty acid residue moiety consists only of straight-chain fatty acid residues having an even number of carbon atoms.

    摘要翻译: 毛发生长剂包含作为活性成分的一种或多种选自溶血磷脂酸和磷脂酸的成员,其中脂肪酸残基部分仅由具有偶数碳原子的直链脂肪酸残基组成。

    Process for purification of proanthocyanidin oligomer
    7.
    发明授权
    Process for purification of proanthocyanidin oligomer 失效
    纯化原花青素低聚物的方法

    公开(公告)号:US06800433B1

    公开(公告)日:2004-10-05

    申请号:US09959274

    申请日:2001-10-19

    IPC分类号: C12Q100

    CPC分类号: C07D311/62 C07D311/60

    摘要: The present invention relates to a process for purifying dimeric to pentameric proanthocyanidin oligomers which comprises extracting the proanthocyanidin oligomers from raw materials containing the proanthocyanidin oligomers or crude purification products therefrom by solid-liquid extraction using methyl acetate as a liquid phase; a process for purifying dimeric to pentameric proanthocyanidin oligomers which comprises pretreating with an enzyme for hydrolysis raw materials containing the proanthocyanidin oligomers, crude purification products therefrom, or a solution containing one of these; and a process for purifying dimeric to pentameric proanthocyanidin oligomers with a uniform polymerization degree which comprises separating and purifying the proanthocyanidin oligomers by polymerization degree from raw materials containing the proanthocyanidin oligomers or crude purification products there from by normal phase silica gel liquid chromatography using as a mobile phase a single solvent or a mixed solvent of two or more solvents selected from the group consisting of an ester solvent, a ketone solvent, a hydrocarbon solvent, an ether solvent and an alcohol solvent.

    摘要翻译: 本发明涉及一种纯化二聚至五聚原花青素低聚物的方法,该方法包括通过使用乙酸甲酯作为液相通过固液萃取从原料中提取原花青素低聚物或粗提纯产物; 用于纯化二聚体至五聚原花青素低聚物的方法,其包括用酶预处理含有原花青素低聚物的水解原料,其粗提纯产物或含有这些之一的溶液; 以及具有均匀聚合度的二聚至五聚原花青素低聚物的纯化方法,该方法包括通过使用作为流动相的正相硅胶液相色谱法从含有原花青素低聚物或粗纯化产物的原料中分离纯化原花青素低聚物 将溶剂选自酯溶剂,酮溶剂,烃溶剂,醚溶剂和醇溶剂中的两种或更多种溶剂的单一溶剂或混合溶剂。

    Hair-growing agent
    8.
    发明授权
    Hair-growing agent 失效
    发丝剂

    公开(公告)号:US06562804B2

    公开(公告)日:2003-05-13

    申请号:US10073113

    申请日:2002-02-12

    IPC分类号: A61K3166

    摘要: The present invention provides a hair-growing agent comprising, as an active ingredient, a phosphatidic acid represented by formula (I): (wherein R1 represents alkyl, alkenyl, alkanoyl or alkenoyl; and when R1 represents alkyl or alkenyl, R2 represents alkyl, alkenyl, alkanoyl or alkenoyl, and when R1 represents alkanoyl or alkenoyl, R2 represents alkyl or alkenyl).

    摘要翻译: 本发明提供一种毛发生长剂,其包含作为活性成分的由式(I)表示的磷脂酸:(其中R 1表示烷基,烯基,烷酰基或烯酰基;当R 1表示烷基或烯基时,R 2表示烷基, 烯基,烷酰基或烯酰基,当R 1表示烷酰基或烯酰基时,R 2表示烷基或链烯基)。

    Citrulline-containing beverage
    9.
    发明授权
    Citrulline-containing beverage 有权
    含瓜氨酸的饮料

    公开(公告)号:US08679568B2

    公开(公告)日:2014-03-25

    申请号:US12743172

    申请日:2008-11-17

    IPC分类号: B23K20/233

    摘要: The invention provides an easy-to-drink beverage that contains citrulline, wherein the generation of bad odors due to storage or heating is suppressed. In particular, the invention provides a beverage that contains citrulline and citric acid, as well as sodium citrate or disodium hydrogen phosphate.

    摘要翻译: 本发明提供一种含有瓜氨酸的容易饮用饮料,其中抑制由储存或加热引起的不良气味的产生。 特别地,本发明提供含有瓜氨酸和柠檬酸以及柠檬酸钠或磷酸氢二钠的饮料。

    Hair-growing agent
    10.
    发明授权
    Hair-growing agent 失效
    发丝剂

    公开(公告)号:US06562803B2

    公开(公告)日:2003-05-13

    申请号:US10073107

    申请日:2002-02-12

    IPC分类号: A61K3166

    CPC分类号: A61K8/553 A61Q7/00

    摘要: The present invention provides a hair-growing agent comprising, as an active ingredient, a phosphatidic acid represented by formula (I): (wherein R1 represents straight-chain alkyl having an odd number of carbon atoms, straight-chain alkenyl having an odd number of carbon atoms, or straight-chain alkynyl having an odd number of carbon atoms).

    摘要翻译: 本发明提供一种毛发生长剂,其包含作为活性成分的由式(I)表示的磷脂酸:(其中R1表示具有奇数个碳原子的直链烷基,具有奇数的直链烯基) 的碳原子或具有奇数个碳原子的直链炔基)。