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1.发明授权Method of preventing or ameliorating psoriasis using pyrroloquinoline quinone compounds 有权使用吡咯喹啉醌化合物预防或改善牛皮癣的方法公开(公告)号：US08575190B2
公开(公告)日：2013-11-05
申请号：US12742351
申请日：2008-11-12
IPC分类号： A61K31/44
CPC分类号： C07D471/04
摘要： The present invention provides a method for preventing or ameliorating skin psoriasis by applying as an active ingredient, a compound represented by general formula (I) or a salt thereof: (wherein R1, R2, and R3 simultaneously or separately represent a lower alkyl, lower alkenyl, lower alkynyl, aralkyl, araryl, or phenyl group, or a hydrogen atom).
摘要翻译： 本发明提供一种通过施用作为活性成分的通式（I）表示的化合物或其盐来预防或改善皮肤银屑病的方法：（其中R1，R2和R3同时或分别代表低级烷基，低级 烯基，低级炔基，芳烷基，芳芳基或苯基，或氢原子）。
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2.发明申请METHOD OF PREVENTING OR AMELIORATING PSORIASIS USING PYRROLOQUINOLINE QUINONE COMPOUNDS 有权使用吡咯啉喹啉化合物防止或增强PSORIASIS的方法公开(公告)号：US20100261749A1
公开(公告)日：2010-10-14
申请号：US12742351
申请日：2008-11-12
IPC分类号： A61K31/475 , A61P17/06
CPC分类号： C07D471/04
摘要： It is an object of the present invention to provide a safe and highly effective preventing or ameliorating agent for skin psoriasis.The present invention provides a preventing or ameliorating agent for skin psoriasis, containing, as an active ingredient, a compound represented by general formula (I) or a salt thereof: (wherein R1, R2, and R3 simultaneously or separately represent a lower alkyl, lower alkenyl, lower alkynyl, aralkyl, araryl, or phenyl group, or a hydrogen atom).
摘要翻译： 本发明的目的是提供一种安全且高效的防止或改善皮肤银屑病的药剂。 本发明提供一种皮肤银屑病的预防或改善剂，其含有通式（I）所示的化合物或其盐作为有效成分：（其中R1，R2和R3同时或分别表示低级烷基， 低级烯基，低级炔基，芳烷基，芳芳基或苯基，或氢原子）。
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公开(公告)号：US20100093780A1
公开(公告)日：2010-04-15
申请号：US12440807
申请日：2007-09-19
IPC分类号： A61K31/437 , A61P3/10
CPC分类号： A61K31/437 , A23G3/364 , A23G4/12 , A23L33/10 , A23V2002/00 , A23V2200/328 , C07D471/04 , Y10S514/866
摘要： An object of the present invention is to provide a safe and highly effective insulin resistance improving agent or therapeutic agent for type II diabetes. According to the present invention, an insulin resistance improving agent or a therapeutic agent for type II diabetes comprising a compound represented by general formula (I) (wherein R1, R2, and R3 are the same as or different from each other, and each represents lower alkyl, lower alkenyl, lower alkynyl, aralkyl, araryl, phenyl, or a hydrogen atom) or a salt thereof as an active ingredient can be provided.
摘要翻译： 本发明的目的是提供一种安全高效的胰岛素抵抗改善剂或II型糖尿病治疗剂。 根据本发明，提供一种胰岛素抵抗性改善剂或II型糖尿病治疗剂，其含有通式（I）表示的化合物（其中，R1，R2和R3彼此相同或不同，表示 低级烷基，低级烯基，低级炔基，芳烷基，芳芳基，苯基或氢原子）或其盐作为有效成分。
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公开(公告)号：US08097635B2
公开(公告)日：2012-01-17
申请号：US12440807
申请日：2007-09-19
IPC分类号： A61K31/44
CPC分类号： A61K31/437 , A23G3/364 , A23G4/12 , A23L33/10 , A23V2002/00 , A23V2200/328 , C07D471/04 , Y10S514/866
摘要： An object of the present invention is to provide a safe and highly effective insulin resistance improving agent or therapeutic agent for type II diabetes. According to the present invention, an insulin resistance improving agent or a therapeutic agent for type II diabetes comprising a compound represented by general formula (I) (wherein R1, R2, and R3 are the same as or different from each other, and each represents lower alkyl, lower alkenyl, lower alkynyl, aralkyl, araryl, phenyl, or a hydrogen atom) or a salt thereof as an active ingredient can be provided.
摘要翻译： 本发明的目的是提供一种安全高效的胰岛素抵抗改善剂或II型糖尿病治疗剂。 根据本发明，提供一种胰岛素抵抗性改善剂或II型糖尿病治疗剂，其含有通式（I）表示的化合物（其中，R1，R2和R3彼此相同或不同，表示 低级烷基，低级烯基，低级炔基，芳烷基，芳芳基，苯基或氢原子）或其盐作为有效成分。
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公开(公告)号：US20100190815A1
公开(公告)日：2010-07-29
申请号：US12440069
申请日：2007-09-07
IPC分类号： A61K31/475
CPC分类号： C07D471/04 , A23K20/137 , A23L33/10 , A23V2002/00 , A61K31/437 , A23V2200/326
摘要： It is an objective of the present invention to provide a safe and highly effective hypertension-ameliorating agent.The present invention provides a hypertension-ameliorating agent, comprising a compound represented by general formula (I) (wherein R1, R2, and R3 are the same as or different from each other, and each represents lower alkyl, lower alkenyl, lower alkynyl, aralkyl, araryl, phenyl, or a hydrogen atom) or a salt thereof as an active ingredient.
摘要翻译： 本发明的目的是提供一种安全有效的高血压改善剂。 本发明提供一种高血压改善剂，其包含通式（I）表示的化合物（其中，R 1，R 2和R 3相同或不同，各自表示低级烷基，低级链烯基，低级炔基， 芳烷基，芳芳基，苯基或氢原子）或其盐作为活性成分。
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6.发明申请Brain Function-Improving Agent, and Functional Food Containing the Improving Agent 审中-公开脑功能改善剂和含改善剂的功能性食品公开(公告)号：US20090192312A1
公开(公告)日：2009-07-30
申请号：US12226222
申请日：2007-03-29
申请人： Kazutoshi Kikkawa , Masahiko Nakano , Shiro Urano
发明人： Kazutoshi Kikkawa , Masahiko Nakano , Shiro Urano
IPC分类号： C07D471/04 , A61P25/00
CPC分类号： C07D471/04 , A23L2/52 , A23L33/10 , A23V2002/00 , A61K31/122 , A61K31/4745 , A61K2300/00 , A23V2200/322 , A23V2250/314 , A23V2250/30
摘要： There are provided a brain function improving agent having an effect of improving learning and memory abilities, and a functional food containing the function improving agent. A preparation comprising a pyrroloquinoline quinone or a salt thereof alone or in combination with coenzyme Q10 and a functional food containing the preparation can improve learning and memory abilities decreased due to brain function disorders caused by various factors.
摘要翻译： 提供了具有提高学习和记忆能力的效果的脑功能改善剂和含有功能改善剂的功能性食品。 包含吡咯并喹啉醌或其盐单独或与辅酶Q10组合的制剂和含有该制剂的功能性食品可以改善由于各种因素引起的脑功能障碍而降低的学习和记忆能力。
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公开(公告)号：US07343738B2
公开(公告)日：2008-03-18
申请号：US11169639
申请日：2005-06-30
申请人： Naoya Tsutsumoto , Junichi Kawashima , Masahiko Nakano , Makoto Ootake , Shouichirou Ueno , Terunori Kondou , Toshimasa Koga
发明人： Naoya Tsutsumoto , Junichi Kawashima , Masahiko Nakano , Makoto Ootake , Shouichirou Ueno , Terunori Kondou , Toshimasa Koga
摘要： An engine controller (20) controls regeneration of a diesel particulate filter (11) deployed along an exhaust passage (3) of a vehicle diesel engine (9). Regeneration terminates in response to a terminating request based on running conditions of the diesel engine (1). When the regeneration elapsed time at the time of termination is shorter than a reference duration, the engine controller (20) adds a time corresponding to a deviation of the regeneration elapsed time from the reference duration to the reference duration for the next regeneration of the DPF (11), thereby completely removing particulate matter accumulated in and around an inlet (18) of the filter (11).
摘要翻译： 发动机控制器（20）控制沿着车辆柴油发动机（9）的排气通道（3）展开的柴油机微粒过滤器（11）的再生。 响应于基于柴油发动机（1）的运行状态的终止请求而终止再生。 当终止时的再生经过时间比参考持续时间短时，发动机控制器（20）将与再生经过时间的偏差相对应的时间从参考持续时间加到DPF的下次再生的参考持续时间 （11），从而完全除去积聚在过滤器（11）的入口（18）内和周围的颗粒物质。
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公开(公告)号：US20060042238A1
公开(公告)日：2006-03-02
申请号：US11210103
申请日：2005-08-24
申请人： Toshimasa Koga , Junichi Kawashima , Makoto Ootake , Masahiko Nakano , Terunori Kondou , Shouichirou Ueno , Naoya Tsutsumoto
发明人： Toshimasa Koga , Junichi Kawashima , Makoto Ootake , Masahiko Nakano , Terunori Kondou , Shouichirou Ueno , Naoya Tsutsumoto
IPC分类号： F01N3/00
CPC分类号： F01N3/023 , F01N9/002 , F02B37/00 , F02D41/1446 , F02D2200/0812 , Y02T10/47
摘要： A particulate matter deposit amount accumulated in a diesel particulate filter (4) is calculated as a first particulate matter deposit amount from a pressure loss of the filter (4) (S33). The particulate matter deposit amount accumulated in the filter (4) is calculated as a second particulate matter deposit amount from another parameter (S34). It is determined whether or not there is front end blockage of the filter (4) based on a comparison between the first particulate matter deposit amount and second particulate matter deposit amount (S36, S43). When there is a front end blockage of the filter (4), the regeneration device is controlled to perform regeneration of the filter (4) for a longer period than the normal regeneration period of the filter (4) (S22).
摘要翻译： 由过滤器（4）的压力损失计算在柴油机微粒过滤器（4）中累积的颗粒物质沉积量作为第一颗粒物质沉积量（S33）。 累积在过滤器（4）中的颗粒物质沉积量根据另一个参数计算为第二颗粒物质沉积量（S34）。 基于第一颗粒物质沉积量和第二颗粒物质沉积量之间的比较，确定过滤器（4）是否存在前端堵塞（S36，S43）。 当过滤器（4）存在前端堵塞时，控制再生装置比过滤器（4）的正常再生期间更长的时间进行过滤器（4）的再生（S22）。
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公开(公告)号：US20060016177A1
公开(公告)日：2006-01-26
申请号：US11169639
申请日：2005-06-30
申请人： Naoya Tsutsumoto , Junichi Kawashima , Masahiko Nakano , Makoto Ootake , Shouichirou Ueno , Terunori Kondou , Toshimasa Koga
发明人： Naoya Tsutsumoto , Junichi Kawashima , Masahiko Nakano , Makoto Ootake , Shouichirou Ueno , Terunori Kondou , Toshimasa Koga
IPC分类号： F01N3/00
摘要： An engine controller (20) controls regeneration of a diesel particulate filter (11) deployed along an exhaust passage (3) of a vehicle diesel engine (9). Regeneration terminates in response to a terminating request based on running conditions of the diesel engine (1). When the regeneration elapsed time at the time of termination is shorter than a reference duration, the engine controller (20) adds a time corresponding to a deviation of the regeneration elapsed time from the reference duration to the reference duration for the next regeneration of the DPF (11), thereby completely removing particulate matter accumulated in and around an inlet (18) of the filter (11).
摘要翻译： 发动机控制器（20）控制沿着车辆柴油发动机（9）的排气通道（3）展开的柴油机微粒过滤器（11）的再生。 响应于基于柴油发动机（1）的运行状态的终止请求而终止再生。 当终止时的再生经过时间比参考持续时间短时，发动机控制器（20）将与再生经过时间的偏差相对应的时间从参考持续时间加到DPF的下次再生的参考持续时间 （11），从而完全除去积聚在过滤器（11）的入口（18）内和周围的颗粒物质。
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10.发明授权
公开(公告)号：US5945211A
公开(公告)日：1999-08-31
申请号：US797625
申请日：1997-02-07
IPC分类号： A61L2/16 , C04B41/50 , C04B41/87 , D06M11/44 , D06M16/00 , D06M23/06 , D21H17/64 , D21H17/65 , D21H17/70 , B32B3/26
CPC分类号： C04B41/009 , A61L2/16 , C04B41/5049 , C04B41/87 , D06M11/44 , D06M16/00 , D06M23/06 , D21H17/70 , C04B2111/20 , D21H17/64 , D21H17/65 , Y10T428/252 , Y10T428/2958
摘要： A zinc oxide fine particle-adhered composite material consists essentially of a substrate and zinc oxide fine particles adhered thereto. The composite material is characterized in that the zinc oxide fine particles deposited, from an aqueous medium, on the surface of the substrate are firmly adhered to the surface without using any binder and the zinc oxide fine particles are substantially exposed on the surface. The composite material is prepared by, for instance, a method which comprises the step of coming an aqueous suspension of zinc oxide fine particle in contact with a substrate to thus deposit the zinc oxide fine particles on the surface of the substrate. The composite material allows for the zinc oxide particles to sufficiently show their antibacterial, deodorizing, UV absorbing, photocatalytic, stain-proofing and purifying activities without any delay.
摘要翻译： 氧化锌微粒子附着复合材料基本上由基材和附着于其上的氧化锌微粒构成。 复合材料的特征在于，从水性介质沉积在基材表面上的氧化锌细颗粒牢固地粘附到表面上而不使用任何粘合剂，并且氧化锌微粒基本上暴露在表面上。 复合材料通过例如包括将氧化锌微粒的水性悬浮液与基材接触从而将氧化锌微粒沉积在基材表面上的方法来制备。 复合材料允许氧化锌颗粒充分显示其抗菌，除臭，紫外线吸收，光催化，防污和净化活性，没有任何延迟。
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