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    Amyloid-β binding peptides
    2.
    发明授权
    Amyloid-β binding peptides 有权
    淀粉样蛋白-β结合肽

    公开(公告)号：US08492341B2

    公开(公告)日：2013-07-23

    申请号：US12514738

    申请日：2007-11-15

    申请人： Ralph Martins ,  Trevor Payne

    发明人： Ralph Martins ,  Trevor Payne

    IPC分类号： A61K38/08 ,  A61P25/28 ,  C07K7/06 ,  C07K1/06 ,  A61K51/12

    CPC分类号： C07K7/06 ,  A61K38/00 ,  G01N2800/2821

    摘要： A peptide sequence of the form: X(Lys,Arg)XXXXX(Arg,Lys)X, wherein Lys and Arg are replaceable and X is preferably one or more of the following amino acids: hydrophobic amino acid residues (eg Pro, Leu, Met, Ile), basic amino acid residues or threonine; and wherein the sequence is capable of engaging Aβ and ameliorating its SOD activity and/or metal ion binding.

    摘要翻译： X（Lys，Arg）XXXXX（Arg，Lys）X的肽序列，其中Lys和Arg是可取代的，X优选为以下氨基酸中的一个或多个：疏水性氨基酸残基（例如Pro，Leu， Met，Ile），碱性氨基酸残基或苏氨酸; 并且其中所述序列能够接合Abeta并改善其SOD活性和/或金属离子结合。

    DISPENSING DEVICE AND METHOD OF MANUFACTURE
    3.
    发明申请
    DISPENSING DEVICE AND METHOD OF MANUFACTURE 审中-公开
    分配装置及其制造方法

    公开(公告)号：US20130104304A1

    公开(公告)日：2013-05-02

    申请号：US13698034

    申请日：2011-05-13

    申请人： Brian Wilson ,  Matthew Stevenson ,  Trevor Payne

    发明人： Brian Wilson ,  Matthew Stevenson ,  Trevor Payne

    IPC分类号： E03D9/03

    CPC分类号： E03D9/032 ,  E03D2009/024 ,  Y10T29/49826

    摘要： A toilet bowl treatment composition dispensing device, comprising a hanger and a treatment composition block. The hanger (20) comprises an elongate body portion (21) having a first end and a second end; a hook portion (22) at the first end for suspending the hanger (20) from a rim of a toilet bowl; and a block supporting portion (23) at the second end, the block supporting portion (23) having at least one finger (25) projecting from a surface of the supporting portion. Wherein the hook portion (22) and the at least one finger (25) project from one of the same longitudinal side of the body portion (21), and opposite longitudinal sides of the body portion (21), and the treatment composition block (10) is retained on the supporting portion (23) by said at least one finger inserted into a surface of said treatment composition block.

    摘要翻译： 一种马桶处理组合物分配装置，包括衣架和处理组合物块。 衣架（20）包括具有第一端和第二端的细长主体部分（21） 在第一端处的钩部分（22），用于将衣架（20）从马桶的边缘悬吊; 以及在第二端处的块支撑部分（23），所述块支撑部分（23）具有从所述支撑部分的表面突出的至少一个指状物（25）。 其中，所述钩部（22）和所述至少一个指状物（25）从所述主体部（21）的同一纵向侧和所述主体部（21）的相对的纵向侧和所述处理组合物块 10）通过插入到所述处理组合物块的表面中的所述至少一根手指保持在所述支撑部分（23）上。

    Improved Peptide Composition
    4.
    发明申请
    Improved Peptide Composition 有权
    改进的肽组成

    公开(公告)号：US20100173850A1

    公开(公告)日：2010-07-08

    申请号：US12514738

    申请日：2007-11-15

    申请人： Ralph Martins ,  Trevor Payne

    发明人： Ralph Martins ,  Trevor Payne

    IPC分类号： C07K7/06 ,  A61K38/08 ,  A61P25/28

    CPC分类号： C07K7/06 ,  A61K38/00 ,  G01N2800/2821

    摘要： A peptide sequence of the form: X(Lys,Arg)XXXXX(Arg,Lys)X, wherein Lys and Arg arc replaceable and X is preferably one or more of the following amino acids: hydrophobic amino acid residues (eg Pro, Leu. Met, Ile), basic amino acid residues or threonine; and wherein the sequence is capable of engaging Λβ and ameliorating its SOD activity and/or metal ion binding.

    摘要翻译： 具有以下形式的肽序列：X（Lys，Arg）XXXXX（Arg，Lys）X，其中Lys和Arg可替代，X优选为以下氨基酸中的一个或多个：疏水性氨基酸残基（例如Pro，Leu。 Met，Ile），碱性氨基酸残基或苏氨酸; 并且其中所述序列能够接合Λ和bgr; 并改善其SOD活性和/或金属离子结合。

    Cotton ginning apparatus
    5.
    发明授权
    Cotton ginning apparatus 失效
    棉花轧花机

    公开(公告)号：US08272106B2

    公开(公告)日：2012-09-25

    申请号：US12742695

    申请日：2007-11-16

    申请人： Trevor Payne

    发明人： Trevor Payne

    IPC分类号： D01B1/04

    CPC分类号： D01B1/04

    摘要： A driven conveyor having an upper surface for receiving and transporting seed cotton comprises a plurality of spaced apart slats, each extending transversely relative to the direction of travel. Each slat has a roughened surface to which cotton fiber will adhere. The transverse gaps between the respective slats facilitate severance of seed by a transverse blade that is in contact with the upper surface of the conveyor, while the cotton fiber adheres to the slatted upper surface and is pulled through the pinch point between the blade and the conveyor. An air flow chamber is arranged above the blade so that seed separated from the fiber at the pinch point can be removed. An air suction device is provided downstream of the blade for removal of the fiber from the upper surface. A blade mounting assembly resiliently biases the blade in floating contact with the upper surface of the conveyor.

    摘要翻译： 具有用于接收和运输种子棉的上表面的从动输送机包括多个间隔开的板条，每个板条相对于行进方向横向延伸。 每个板条都有粗糙的表面，棉纤维将粘附在其上。 相应板条之间的横向间隙有助于通过与输送机上表面接触的横向叶片来切断种子，同时棉纤维粘附到板条上表面并被拉动通过叶片与输送机之间的夹点 。 气流室设置在叶片上方，从而可以除去在夹点处从纤维分离的种子。 空气抽吸装置设置在叶片的下游，用于从上表面移除纤维。 叶片安装组件弹性地偏压叶片与输送机的上表面浮动接触。

    COTTON GINNING APPARATUS
    6.
    发明申请
    COTTON GINNING APPARATUS 失效

    公开(公告)号：US20100269305A1

    公开(公告)日：2010-10-28

    申请号：US12742695

    申请日：2007-11-16

    申请人： Trevor Payne

    发明人： Trevor Payne

    IPC分类号： D01B1/04

    CPC分类号： D01B1/04

    摘要： A driven conveyor (10) having an upper surface for receiving and transporting seed cotton in a forward direction of travel A comprises a plurality of spaced apart slats (20), each extending transversely relative to the direction of travel. Each slat (20) has an upper layer (22) of surface roughened material to which cotton fibre will adhere. The slats (20) are preferably mounted between a pair of substantially parallel endless chains (24), each formed of plural chain links (26) and having rollers (28) mounted thereto whereby the chains are guided along respective guide tracks (16) at each side of the machine frame (12). The transverse gaps between the respective slats (20) facilitate severance of seed by a transverse blade (40) which has a lower surface in contact with the upper surface of the conveyor, while the cotton fibre adheres to the slatted upper surface and is pulled through the pinch point between the blade (40) and the conveyor (10). An air flow chamber (50) is arranged above the blade (40) so that seed separated from the fibre at the pinch point can be removed transversely of the direction of travel of the conveyor (10). An air suction device (52) is provided at a location downstream of the blade (40), for removal of the fibre from said upper surface. Also disclosed are a blade mounting assembly (42-48) which includes a fluid actuated piston (46) arranged to resiliently bias the blade (40) so that the lower surface of the blade remains in floating contact with the upper surface of the conveyor (10). Also disclosed is a seed cotton feed assembly mounted upstream of the blade (40) in which a cylinder (32) having a plurality of radially projecting spikes (36) distributed over its surface is rotatably mounted inside a housing (30) adjacent and parallel to a fixed breaker blade (34) mounted inside the housing with a small gap there between. The position of the cylinder relative to the breaker blade (34) and the length and spacing of the spikes (36) are selected to distribute seed cotton evenly and at a predetermined thickness across the upper surface of the conveyor (10).

    Cotton ginning apparatus and method
    7.
    发明授权
    Cotton ginning apparatus and method 失效
    棉花装置及方法

    公开(公告)号：US6122803A

    公开(公告)日：2000-09-26

    申请号：US65025

    申请日：1998-04-23

    申请人： Trevor Payne

    发明人： Trevor Payne

    IPC分类号： D01B1/06

    CPC分类号： D01B1/06

    摘要： A method and apparatus for ginning harvested seed cotton comprising the steps of: introducing harvested seed cotton including lint and seed on to the upper surface of a lower rotating plate (3); rotating said plate to thereby carry said harvested seed cotton towards the leading edge (29) of a knife positioned at a defined distance above said lower rotating plate such that the cotton seed is drawn/combed under the knife edge (27); extracting line separated from said harvested seed cotton from a rearward facing edge of said knife; and collecting said seed from the leading edge of the knife.

    摘要翻译： PCT No.PCT / GB97 / 01326 Sec。 371日期：1998年4月23日 102（e）日期1998年4月23日PCT提交1997年5月15日PCT公布。 第WO97 / 45572号公报 日期1997年12月4日一种用于轧制收获的种子棉的方法和装置，包括以下步骤：将收获的包括棉绒和种子的种子棉花引入下旋转板（3）的上表面; 旋转所述板，从而将所述收获的种子棉子朝向位于所述下部旋转板上方限定距离的刀的前缘（29）运送，使得棉籽在刀刃（27）下方被拉伸/梳理; 从所述收获的种子棉从所述刀的向后的边缘分离的提取线; 并从刀的前缘收集所述种子。