ADHESIVE PATCH FOR TREATMENT OF TINEA UNGUIUM
    4.
    发明申请
    ADHESIVE PATCH FOR TREATMENT OF TINEA UNGUIUM 有权
    用于治疗TINEA UNGUIUM的胶粘剂

    公开(公告)号:US20120302644A1

    公开(公告)日:2012-11-29

    申请号:US13577110

    申请日:2011-02-07

    IPC分类号: A61K31/137 A61P31/10

    摘要: The present invention provides an adhesive patch for the treatment of tinea unguium intended to be applied once a day, comprising terbinafine and/or a pharmacologically acceptable salt thereof in an amount of 3 mg/cm2, wherein the adhesive patch is used so that the terbinafine concentration in nails may be 295±127 ng/mg and the terbinafine concentration in plasma may be 23 pg/mL or less, 8 weeks after the start of application, per cm2 of the patch size.

    摘要翻译: 本发明提供了一种用于治疗意图每天一次施用的癣的粘合剂贴剂,其包含3mg / cm 2的特比萘芬和/或其药理学上可接受的盐,其中使用粘合剂片剂使得特比萘芬 钉子中的浓度可以为295±127ng / mg,并且在施用开始后8周,每平方厘米的贴片尺寸,血浆中特比萘芬浓度可以为23pg / mL或更少。

    Adhesive patch for treatment of tinea unguium
    5.
    发明授权
    Adhesive patch for treatment of tinea unguium 有权
    用于治疗癣的粘合剂

    公开(公告)号:US08574621B2

    公开(公告)日:2013-11-05

    申请号:US13577110

    申请日:2011-02-07

    IPC分类号: A61F13/02 A61K31/135

    摘要: The present invention provides an adhesive patch for the treatment of tinea unguium intended to be applied once a day, comprising terbinafine and/or a pharmacologically acceptable salt thereof in an amount of 3 mg/cm2, wherein the adhesive patch is used so that the terbinafine concentration in nails may be 295±127 ng/mg and the terbinafine concentration in plasma may be 23 pg/mL or less, 8 weeks after the start of application, per cm2 of the patch size.

    摘要翻译: 本发明提供了一种用于治疗意图每天一次施用的癣的粘合剂贴剂,其包含3mg / cm 2的特比萘芬和/或其药理学上可接受的盐,其中使用粘合剂片剂使得特比萘芬 钉子中的浓度可以为295±127ng / mg,并且在施用开始后8周,每平方厘米的贴片尺寸,血浆中特比萘芬浓度可以为23pg / mL或更少。