-
公开(公告)号：US20180201908A1
公开(公告)日：2018-07-19
申请号：US15315687
申请日：2015-06-19
申请人： UNIVERSITÉ D'AIX-MARSEILLE , INSERM
发明人： Antoine Nougairéde , Lauriane De Fabritus , Fabien Aubry , Xavier De Lamballerie , Ernest Andrew Gould
CPC分类号： C12N7/04 , A61K39/12 , A61K2039/525 , A61K2039/5254 , C12N7/00 , C12N15/1031 , C12N2770/24051 , C12N2770/24151 , Y02A50/383 , Y02A50/39 , Y02A50/396
摘要： The present invention harnesses the power of mutagenesis to produce an attenuated RNA virus in a very short period, i.e. as soon as the complete sequence of the target virus is known and an infectious genome can be produced.
-
公开(公告)号：US20200270584A1
公开(公告)日：2020-08-27
申请号：US16813179
申请日：2020-03-09
申请人： UNIVERSITÉ D'AIX-MARSEILLE , INSERM
发明人： Antoine Nougairéde , Lauriane De Fabritus , Fabien Aubry , Xavier De Lamballerie , Ernest Andrew Gould
摘要： The present invention harnesses the power of mutagenesis to produce an attenuated RNA virus in a very short period, i.e. as soon as the complete sequence of the target virus is known and an infectious genome can be produced.
-
公开(公告)号：US10407667B2
公开(公告)日：2019-09-10
申请号：US15315667
申请日：2015-06-19
申请人： UNIVERSITÉ D'AIX-MARSEILLE , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)
发明人： Fabien Aubry , Antoine Nougairéde , Gilles Quérat , Xavier De Lamballerie , Ernest Andrew Gould , Lauriane De Fabritus
摘要： The present invention relates to a method for rapid generation of an infectious RNA virus that completely eliminates the need of constructing a full-length c DNA, which covers the entire viral genome, cloning and propagating such full length c DNA.
-
公开(公告)号：US20180208907A1
公开(公告)日：2018-07-26
申请号：US15315667
申请日：2015-06-19
发明人： Fabien Aubry , Antoine Nougairéde , Gilles Quérat , Xavier De Lamballerie , Ernest Andrew Gould , Lauriane De Fabritus
IPC分类号： C12N7/02
CPC分类号： C12N7/02 , A61K2039/525 , C12N7/00 , C12N2770/24051 , C12N2770/24151 , C12N2999/007 , Y02A50/383 , Y02A50/386 , Y02A50/388 , Y02A50/39 , Y02A50/394 , Y02A50/396 , Y02A50/51
摘要： The present invention relates to a method for rapid generation of an infectious RNA virus that completely eliminates the need of constructing a full-length c DNA, which covers the entire viral genome, cloning and propagating such full length c DNA.
-
公开(公告)号：US10098879B2
公开(公告)日：2018-10-16
申请号：US15546362
申请日：2016-01-27
申请人： INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , Xavier Anglaret , UNIVERSITÉ DE BORDEAUX , CHU DE BOURDEAUX , TOYAMA CHEMICAL CO., LTD
发明人： Denis Malvy , Sylvain Baize , Xavier De Lamballerie , Hervé Raoul , Cédric Laouenan , Jeremie Guedj , France Mentre
IPC分类号： A61K31/4965 , C12Q1/70
摘要： The invention relates to methods and pharmaceutical compositions for the treatment of Ebola Virus Disease. In particular the present relates to a method of treating Ebola Virus Disease in a subject in need thereof comprising administering the subject with a therapeutically effective amount of Favipiravir.
-
-
-
-
搜索结果
5 条记录 (耗时 0.014 秒)
