Patent search ap:("University of Washington through its Center for Commercialization") AND inv:"Selvi Srinivasan" Page 1

1.

发明授权
Stimuli-responsive polymer diagnostic assay comprising magnetic nanoparticles and capture conjugates 有权
Title translation: 刺激响应性聚合物诊断测定，其包括磁性纳米颗粒和捕获缀合物

公开(公告)号：US09080933B2

公开(公告)日：2015-07-14

申请号：US13891005

申请日：2013-05-09

Applicant: University of Washington through its Center for Commercialization

Inventor： Patrick S. Stayton , Jriuan Lai , Barrett J. Nehilla , Selvi Srinivasan

IPC: G01N1/34 , C12Q1/68 , B82Y25/00 , G01N1/00 , B01D21/00 , C12N15/10 , G01N27/74 , G01N33/543 , B03C1/01 , B03C1/28 , G01N1/40

CPC classification number: G01N33/54306 , B01D21/0009 , B03C1/01 , B03C1/288 , B03C2201/18 , B03C2201/26 , B82Y25/00 , C12N15/1013 , C12Q1/6834 , G01N1/34 , G01N27/745 , G01N33/54333 , G01N33/54346 , G01N33/545 , G01N2001/4038 , G01N2001/4088 , G01N2446/20 , G01N2446/84 , Y02A50/53 , Y02A50/58 , Y10T436/00 , Y10T436/25 , Y10T436/255 , C12Q2563/143 , C12Q2563/155

Abstract: The present disclosure utilizes the aggregation of stimuli-responsive polymers to isolate a diagnostic target (e.g., an antigen) from a solution using magnetophoresis. Isolating the diagnostic target provides a route to identify the presence of the diagnostic target in the solution.

Abstract translation: 本公开使用刺激响应聚合物的聚集来使用磁电泳从溶液中分离诊断靶（例如抗原）。隔离诊断目标提供了一种路径，用于识别解决方案中诊断目标的存在。

2.

发明申请
STIMULI-RESPONSIVE POLYMER DIAGNOSTIC ASSAY COMPRISING MAGNETIC NANOPARTICLES AND CAPTURE CONJUGATES 审中-公开
Title translation: 包含磁性纳米颗粒和捕获结合物的刺激性聚合物诊断测定

公开(公告)号：US20150268236A1

公开(公告)日：2015-09-24

申请号：US14732428

申请日：2015-06-05

Applicant: University of Washington through its Center for Commercialization

Inventor： Patrick S. Stayton , Jriuan Lai , Barrett J. Nehilla , Selvi Srinivasan

IPC: G01N33/543 , G01N1/34

CPC classification number: G01N33/54306 , B01D21/0009 , B03C1/01 , B03C1/288 , B03C2201/18 , B03C2201/26 , B82Y25/00 , C12N15/1013 , C12Q1/6834 , G01N1/34 , G01N27/745 , G01N33/54333 , G01N33/54346 , G01N33/545 , G01N2001/4038 , G01N2001/4088 , G01N2446/20 , G01N2446/84 , Y02A50/53 , Y02A50/58 , Y10T436/00 , Y10T436/25 , Y10T436/255 , C12Q2563/143 , C12Q2563/155

Abstract: The present disclosure utilizes the aggregation of stimuli-responsive polymers to isolate a diagnostic target (e.g., an antigen) from a solution using magnetophoresis. Isolating the diagnostic target provides a route to identify the presence of the diagnostic target in the solution.

Abstract translation: 本公开使用刺激响应聚合物的聚集来使用磁电泳从溶液中分离诊断靶（例如抗原）。隔离诊断目标提供了一种路径，用于识别解决方案中诊断目标的存在。

3.

发明申请
RANDOM COPOLYMER THERAPEUTIC AGENT CARRIERS AND ASSEMBLIES THEREOF 审中-公开
Title translation: 随机共聚物治疗药物及其组合物

公开(公告)号：US20160279251A1

公开(公告)日：2016-09-29

申请号：US15035721

申请日：2014-11-12

Applicant: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION

Inventor： Patrick S. Stayton , Anthony Convertine , Daniel M. Ratner , Selvi Srinivasan , Debobrato Das , Fang-Yi Su , Jasmin Chen , David Yee-Shawn Chiu , Daniel Douglas Lane

IPC: A61K47/48 , A61K31/407 , A61K31/4745 , A61K31/7036 , A61K31/337 , A61K31/496

CPC classification number: A61K47/58 , A61K9/1075 , A61K9/1271 , A61K31/337 , A61K31/407 , A61K31/4745 , A61K31/496 , A61K31/7036 , A61K47/60 , A61K47/644 , A61K47/6907 , A61K47/6915

Abstract: Provided herein are particles assemblies including a shell surrounding a core. The shell includes a particle-stabilizing random copolymer. The core includes a core random copolymer. The particle assemblies have a biomimetic design in which the polymeric components containing discrete chemical and biological functionalities are designed to spontaneously self-assemble into particles. Also provided herein are random copolymers having conjugated therapeutic agents that can be cleaved from the copolymers by an enzyme or water.

Abstract translation: 本文提供了包括围绕芯的壳的颗粒组件。壳包括颗粒稳定的无规共聚物。核心包括核心无规共聚物。颗粒组件具有仿生设计，其中包含分立的化学和生物功能的聚合物组分被设计成自发地自组装成颗粒。本文还提供了具有共轭治疗剂的无规共聚物，其可以通过酶或水从共聚物中裂解。

4.

发明申请
STIMULI-RESPONSIVE POLYMER DIAGNOSTIC ASSAY COMPRISING MAGNETIC NANOPARTICLES AND CAPTURE CONJUGATES 审中-公开
Title translation: 包含磁性纳米颗粒和捕获结合物的刺激性聚合物诊断测定

公开(公告)号：US20170030900A1

公开(公告)日：2017-02-02

申请号：US15228548

申请日：2016-08-04

Applicant: University of Washington through its Center for Commercialization

Inventor： Patrick S. Stayton , Jriuan Lai , Barrett J. Nehilla , Selvi Srinivasan

IPC: G01N33/543 , B03C1/28 , B03C1/01 , G01N33/545 , C12Q1/68

CPC classification number: G01N33/54306 , B01D21/0009 , B03C1/01 , B03C1/288 , B03C2201/18 , B03C2201/26 , B82Y25/00 , C12N15/1013 , C12Q1/6834 , G01N1/34 , G01N27/745 , G01N33/54333 , G01N33/54346 , G01N33/545 , G01N2001/4038 , G01N2001/4088 , G01N2446/20 , G01N2446/84 , Y02A50/53 , Y02A50/58 , Y10T436/00 , Y10T436/25 , Y10T436/255 , C12Q2563/143 , C12Q2563/155

Abstract: The present disclosure utilizes the aggregation of stimuli-responsive polymers to isolate a diagnostic target (e.g., an antigen) from a solution using magnetophoresis. Isolating the diagnostic target provides a route to identify the presence of the diagnostic target in the solution.

Abstract translation: 本公开使用刺激响应聚合物的聚集来使用磁电泳从溶液中分离诊断靶（例如抗原）。隔离诊断目标提供了一种路径，用于识别解决方案中诊断目标的存在。